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  1. Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are essential for the cardiac extracellular matrix (ECM) remodeling. We investigated differences in serum levels of these markers between pa...

    Authors: Andreas S Kalogeropoulos, Sotirios Tsiodras, Angelos G Rigopoulos, Eleftherios A Sakadakis, Andreas Triantafyllis, Dimitrios TH Kremastinos and Ioannis Rizos

    Citation: BMC Cardiovascular Disorders 2011 11:77

    Content type: Research article

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  2. Oral anticoagulant therapy (OAT) involves many health care disciplines. Even though collaboration between care professionals is assumed to improve the quality of OAT, very little research has been done into th...

    Authors: Hanneke W Drewes, Mattijs S Lambooij, Caroline A Baan, Bert R Meijboom, Wilco C Graafmans and Gert P Westert

    Citation: BMC Cardiovascular Disorders 2011 11:76

    Content type: Research article

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  3. Abdominal aortic calcifications (AAC) predict cardiovascular mortality. A new scoring model for AAC, the Morphological Atherosclerotic Calcification Distribution (MACD) index may contribute with additional inf...

    Authors: Natasha Barascuk, Melanie Ganz, Mads Nielsen, Thomas C Register, Lars M Rasmussen, Morten A Karsdal and Claus Christiansen

    Citation: BMC Cardiovascular Disorders 2011 11:75

    Content type: Research article

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  4. During percutaneous coronary intervention (PCI), dislodgement of atherothrombotic material from coronary lesions can result in distal embolization, and may lead to increased major adverse cardiovascular events...

    Authors: Diana M Sobieraj, C Michael White, Jeffrey Kluger, Vanita Tongbram, Jennifer Colby, Wendy T Chen, Sagar S Makanji, Soyon Lee, Ajibade Ashaye and Craig I Coleman

    Citation: BMC Cardiovascular Disorders 2011 11:74

    Content type: Research article

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  5. Mechanical chest compressions (CCs) have been shown capable of maintaining circulation in humans suffering cardiac arrest for extensive periods of time. Reports have documented a visually normalized coronary b...

    Authors: Henrik Wagner, Bjarne Madsen Hardig, Stig Steen, Trygve Sjoberg, Jan Harnek and Goran K Olivecrona

    Citation: BMC Cardiovascular Disorders 2011 11:73

    Content type: Research article

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  6. The mechanisms of benefit of mineralocorticoid receptors antagonists in congestive heart failure (CHF) are still debated. We hypothesized that aldosterone contributes to pulmonary remodelling and right ventric...

    Authors: Andreanne Chabot, Bao Hua Jiang, Yanfen Shi, Jean-Claude Tardif and Jocelyn Dupuis

    Citation: BMC Cardiovascular Disorders 2011 11:72

    Content type: Research article

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  7. The absence of the I allele of the angiotensin converting enzyme (ACE) gene has been associated with higher levels of circulating ACE, lower nitric oxide (NO) release and hypertension. The purposes of this stu...

    Authors: Hugo AP Santana, Sérgio R Moreira, Willson B Neto, Carla B Silva, Marcelo M Sales, Vanessa N Oliveira, Ricardo Y Asano, Foued S Espíndola, Otávio T Nóbrega, Carmen SG Campbell and Herbert G Simões

    Citation: BMC Cardiovascular Disorders 2011 11:71

    Content type: Research article

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  8. Coronary heart disease (CHD) is highly prevalent amongst the South Asian communities in Britain. The reasons for this excess CHD risk are multifactorial, but in part relate to a susceptibility to diabetes mell...

    Authors: Jeetesh V Patel, Elizabeth A Hughes, Gregory YH Lip and Paramjit S Gill

    Citation: BMC Cardiovascular Disorders 2011 11:70

    Content type: Study protocol

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  9. ST-elevation myocardial infarction (STEMI) patients have risk factors and co-morbidities and require procedures predisposing to healthcare acquired infections (HAIs). As few data exist on the extent and conseq...

    Authors: Michelle C Nash, Joel A Strom and Elizabeth B Pathak

    Citation: BMC Cardiovascular Disorders 2011 11:69

    Content type: Research article

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  10. The aims of this study were to evaluate the awareness of and attitudes towards the 2005 European Society of Cardiology (ESC) guidelines for Heart Failure (HF) of the cardiologists in Pakistan and assess barrie...

    Authors: Sana Shoukat, Saqib A Gowani, Ather M Taqui, Rameez Ul Hassan, Zain A Bhutta, Anum I Malik, Sajjad A Sherjeel, Quratulanne Sheheryar and Sajid H Dhakam

    Citation: BMC Cardiovascular Disorders 2011 11:68

    Content type: Research article

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  11. The aim was to investigate the extent to which it is possible to diagnose suspected carotid calcification from dental panoramic radiography (PR) and to establish an association to periodontal risk.

    Authors: Ralph Tiller, Wolfgang Bengel, Sven Rinke and Dirk Ziebolz

    Citation: BMC Cardiovascular Disorders 2011 11:67

    Content type: Research article

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  12. Susceptibility variants identified by genome-wide association studies (GWAS) have modest effect sizes. Whether such variants provide incremental information in assessing risk for common 'complex' diseases is u...

    Authors: Keyue Ding, Kent R Bailey and Iftikhar J Kullo

    Citation: BMC Cardiovascular Disorders 2011 11:66

    Content type: Research article

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  13. Hypertension is a cardiovascular disorder rapidly emerging as a major public health problem in developing countries. However, the acknowledgement of the prevalence and the significant impact of hypertension in...

    Authors: Sonia Hammami, Sounira Mehri, Said Hajem, Nadia Koubaa, Mohamed A Frih, Samy Kammoun, Mohamed Hammami and Fathi Betbout

    Citation: BMC Cardiovascular Disorders 2011 11:65

    Content type: Research article

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  14. Pulmonary artery aneurysms are a rare condition, frequently associated with pulmonary hypertension. However, the evolution and treatment of this pathology is still not clear.

    Authors: Inês Araújo, Pilar Escribano, María Jesus Lopez-Gude, Carmen Jimenez Lopez-Guarch, Maria Antonia Sanchez, Maria J Ruiz-Cano, Juan Delgado and Jose Cortina

    Citation: BMC Cardiovascular Disorders 2011 11:64

    Content type: Case report

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  15. Mortality and complications after percutaneous coronary intervention is higher when performed after regular duty hours due to challenging patient characteristics, inferior processes of care and limited resourc...

    Authors: Ann Coumbe, Ranjit John, Michael Kuskowski, Mehmet Agirbasli, Edward O McFalls and Selcuk Adabag

    Citation: BMC Cardiovascular Disorders 2011 11:63

    Content type: Research article

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  16. Cardiac inflammation and generation of oxidative stress are known to contribute to trastuzumab (herceptin) induced cardiac toxicity. Toll-like receptors (TLRs) are a part of the innate immune system and are in...

    Authors: Nasser Ghaly Yousif and Fadhil G Al-amran

    Citation: BMC Cardiovascular Disorders 2011 11:62

    Content type: Research article

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  17. Cardiovascular risk functions fail to identify more than 50% of patients who develop cardiovascular disease. This is especially evident in the intermediate-risk patients in which clinical management becomes di...

    Authors: Ruth Martí, Dídac Parramon, Luís García-Ortiz, Fernando Rigo, Manuel A Gómez-Marcos, Irene Sempere, Natividad García-Regalado, Jose I Recio-Rodriguez, Cristina Agudo-Conde, Natalia Feuerbach, Maria Garcia-Gil, Anna Ponjoan, Miquel Quesada and Rafel Ramos

    Citation: BMC Cardiovascular Disorders 2011 11:61

    Content type: Study protocol

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  18. Cardiac rehabilitation has a beneficial effect on the prognosis and quality of life of cardiac patients, and has been found to be cost-effective. This report describes a comprehensive and low cost educational ...

    Authors: Rachel Dankner, Galit Geulayov, Arnona Ziv, Ilia Novikov, Uri Goldbourt and Yaakov Drory

    Citation: BMC Cardiovascular Disorders 2011 11:60

    Content type: Study protocol

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  19. The PANDORA study has recently examined the prevalence of low ankle brachial index (ABI) in subjects with moderate risk of cardiovascular disease. This sub-analysis of the PANDORA study examines the prevalence...

    Authors: Guido Sanna, Donatella Alesso, Malek Mediati, Claudio Cimminiello, Claudio Borghi, Amalia Lucia Fazzari and Mario Mangrella

    Citation: BMC Cardiovascular Disorders 2011 11:59

    Content type: Research article

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  20. Reasons for race and gender differences in controlling elevated low density lipoprotein (LDL) cholesterol may be related to variations in prescribed lipid-lowering therapy. We examined the effect of lipid-lowe...

    Authors: Barbara J Turner, Christopher S Hollenbeak, Mark Weiner and Simon SK Tang

    Citation: BMC Cardiovascular Disorders 2011 11:58

    Content type: Research article

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  21. Several mechanisms are involved in the pathophysiology of the Acute Coronary Syndrome (ACS). We have addressed whether B-type natriuretic peptide (BNP) and high-sensitive C-reactive protein (hsCRP) in admissio...

    Authors: Ricardo León de la Fuente, Patrycja A Naesgaard, Stein Tore Nilsen, Leik Woie, Torbjoern Aarsland, Patricio Gallo, Heidi Grundt, Harry Staines and Dennis WT Nilsen

    Citation: BMC Cardiovascular Disorders 2011 11:57

    Content type: Research article

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  22. Failure to adhere to cardiac medications after acute myocardial infarction (AMI) is associated with increased mortality. Language barriers and preference for traditional medications may predispose certain ethn...

    Authors: Emily J Lai, Maja Grubisic, Anita Palepu, Hude Quan, Kathryn M King and Nadia A Khan

    Citation: BMC Cardiovascular Disorders 2011 11:56

    Content type: Research article

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  23. More than one third of adult population in Estonia has problems with elevated blood pressure (BP). The Hypertension in Estonia (HYPEST) study represents the country's first hypertension-targeted sample collection...

    Authors: Elin Org, Gudrun Veldre, Margus Viigimaa, Peeter Juhanson, Margus Putku, Mai Rosenberg, Kärt Tomberg, Tiina Uuetoa and Maris Laan

    Citation: BMC Cardiovascular Disorders 2011 11:55

    Content type: Research article

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  24. As previously reported there is evidence for a reduction in right to left shunt (RLS) in stroke patients with patent foramen ovale (PFO). This occurs predominantly in patients with cryptogenic stroke (CS). We ...

    Authors: Christian Tanislav, Maximilian Puille, Mathias Grebe, Nicole Sieweke, Jens Allendörfer, Wolfgang Pabst, Manfred Kaps and Frank Reichenberger

    Citation: BMC Cardiovascular Disorders 2011 11:54

    Content type: Research article

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  25. Recent guidelines stressed the need to adopt different values of waist circumference (WC) measurements to define abdominal obesity in different ethnic groups. The aim of this study is to identify WC cutoff poi...

    Authors: M Mohsen Ibrahim, Ahmed A Elamragy, Hanan Girgis and Mona A Nour

    Citation: BMC Cardiovascular Disorders 2011 11:53

    Content type: Research article

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  26. An increasing number of septua- and octogenarians undergo cardiac surgery. Acute kidney injury (AKI) still is a frequent complication after surgery. We examined the incidence of AKI and its impact on 30-day mo...

    Authors: Michael Ried, Thomas Puehler, Assad Haneya, Christof Schmid and Claudius Diez

    Citation: BMC Cardiovascular Disorders 2011 11:52

    Content type: Research article

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  27. A cardio-ankle vascular index (CAVI) has been developed to represent the extent of arteriosclerosis throughout the aorta, femoral artery and tibial artery independent of blood pressure. To practically use CAVI...

    Authors: Tsukasa Namekata, Kenji Suzuki, Norio Ishizuka and Kohji Shirai

    Citation: BMC Cardiovascular Disorders 2011 11:51

    Content type: Research article

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  28. Endothelial function has been shown to be a highly sensitive marker for the overall cardiovascular risk of an individual. Furthermore, there is evidence of important sex differences in endothelial function tha...

    Authors: Simon L Bacon, Kim L Lavoie, André Arsenault, Jocelyn Dupuis, Louise Pilote, Catherine Laurin, Jennifer Gordon, Denyse Gautrin and Alain Vadeboncoeur

    Citation: BMC Cardiovascular Disorders 2011 11:50

    Content type: Study protocol

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  29. Left coronary artery arising from the right sinus of Valsalva is an uncommon congenital coro-nary anomaly that seems to be associated with sudden death in young patients.

    Authors: Bruno C Huber, Franz von Ziegler, Fabian Bamberg, Wolfgang-Michael Franz and Alexander Becker

    Citation: BMC Cardiovascular Disorders 2011 11:49

    Content type: Case report

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  30. The prediction of neurological outcome in comatose patients after cardiac arrest has major ethical and socioeconomic implications. The purpose of this study was to assess the capability of serum neuron-specifi...

    Authors: Cédric Daubin, Charlotte Quentin, Stéphane Allouche, Olivier Etard, Cathy Gaillard, Amélie Seguin, Xavier Valette, Jean-Jacques Parienti, Fabrice Prevost, Michel Ramakers, Nicolas Terzi, Pierre Charbonneau and Damien du Cheyron

    Citation: BMC Cardiovascular Disorders 2011 11:48

    Content type: Research article

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  31. Cardiovascular diseases(CVD), specifically ischaemic heart disease(IHD), are the main causes of death in industrialized countries. Statins are not usually prescribed in the most appropriate way. To ensure the ...

    Authors: Rosa Dalmau, Miriam Boira, Carina Aguilar, Carlos López, Dolors Rodríguez, Delicia Gentille, Domingo Bofill, Eduard Diogene and Josep M Pepió

    Citation: BMC Cardiovascular Disorders 2011 11:47

    Content type: Study protocol

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  32. While the factors for poor adherence for treatment with statins have been highlighted, the impact of their combination on adherence is not clear.

    Authors: Philippe Latry, Mathieu Molimard, Bernard Dedieu, Thierry Couffinhal, Bernard Bégaud and Karin Martin-Latry

    Citation: BMC Cardiovascular Disorders 2011 11:46

    Content type: Research article

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  33. Psychosocial stress has been identified as a risk factor in association with cardiovascular disease but less attention has been paid to heterogeneity in vulnerability to stress. The serial Color Word Test (CWT...

    Authors: Lena André-Petersson, Mona Schlyter, Gunnar Engström, Patrik Tydén and Bo Hedblad

    Citation: BMC Cardiovascular Disorders 2011 11:45

    Content type: Research article

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  34. Directed ultrasonic screening for carotid stenosis is cost-effective in populations with > 5% prevalence of the diagnosis. Occasionally, calcifications in the area of the carotid arteries are incidentally dete...

    Authors: Elias P Johansson, Jan Ahlqvist, Maria Garoff, Kjell Karp, Eva Levring Jäghagen and Per Wester

    Citation: BMC Cardiovascular Disorders 2011 11:44

    Content type: Research article

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  35. Nitric oxide (NO) has been noted to produce ischemic preconditioning (IPC)-mediated cardioprotection. Caveolin is a negative regulator of NO, which inhibits endothelial nitric oxide synthase (eNOS) by making c...

    Authors: Preeti Ajmani, Harlokesh N Yadav, Manjeet Singh and Pyare L Sharma

    Citation: BMC Cardiovascular Disorders 2011 11:43

    Content type: Research article

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  36. High-quality systems have adopted a comprehensive approach to preventive care instead of diagnosis or procedure driven care. The current emphasis on prescribing medications to prevent complications of coronary...

    Authors: Steven M Bradley, Chris L Bryson, Charles Maynard, Thomas M Maddox and Stephan D Fihn

    Citation: BMC Cardiovascular Disorders 2011 11:42

    Content type: Research article

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  37. High sensitive troponin T (hsTnT) and heart fatty acid binding protein (hFABP) are both markers of myocardial injury and predict adverse outcome in patients with systolic heart failure (SHF). We tested whether...

    Authors: Wilfried Dinh, Werner Nickl, Reiner Füth, Mark Lankisch, Georg Hess, Dietmar Zdunek, Thomas Scheffold, Michael Coll Barroso, Klaus Tiroch, Dan Ziegler and Melchior Seyfarth

    Citation: BMC Cardiovascular Disorders 2011 11:41

    Content type: Research article

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  38. To determine if recommended treatment targets, as specified in clinical practice guidelines for the management of cardiovascular disease, reduces the risk of renal complications in high risk patient populations.

    Authors: Sharmini Selvarajah, Yolanda vD Graaf, Frank LJ Visseren and Michiel L Bots

    Citation: BMC Cardiovascular Disorders 2011 11:40

    Content type: Research article

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  39. More women than men have PAD with exception for the stage intermittent claudication (IC). The purpose of this study was to evaluate differences in disease characteristics between men and women when using curre...

    Authors: Birgitta Sigvant, Fredrik Lundin, Bo Nilsson, David Bergqvist and Eric Wahlberg

    Citation: BMC Cardiovascular Disorders 2011 11:39

    Content type: Research article

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  40. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a predictor of cardiovascular events that has been shown to vary with race. The objective of this study was to examine factors associated with this racial vari...

    Authors: Keane K Lee, Stephen P Fortmann, Ann Varady, Joan M Fair, Alan S Go, Thomas Quertermous, Mark A Hlatky and Carlos Iribarren

    Citation: BMC Cardiovascular Disorders 2011 11:38

    Content type: Research article

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  41. Renal function is an important predictor of mortality in patients with myocardial infarction (MI), but changes in the impact over time have not been well described.

    Authors: Thomas Kümler, Gunnar H Gislason, Lars Kober, Finn Gustafsson, Morten Schou and Christian Torp-Pedersen

    Citation: BMC Cardiovascular Disorders 2011 11:37

    Content type: Research article

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  42. Erectile dysfunction (ED), impaired arterial elasticity, elevated resting heart rate as well as increased levels of oxidized LDL and fibrinogen associate with future cardiovascular events. Physical activity is...

    Authors: Hanna Pohjantähti-Maaroos, Ari Palomäki and Juha Hartikainen

    Citation: BMC Cardiovascular Disorders 2011 11:36

    Content type: Research article

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  43. Troponins (highly sensitive biomarkers of myocardial damage) increase counts of myocardial infarction (MI) in clinical practice, but their impact on trends in admission rates for MI in National statistics is u...

    Authors: Frank M Sanfilippo, Michael ST Hobbs, Matthew W Knuiman, Stephen C Ridout, Pamela J Bradshaw, Judith C Finn, Jamie M Rankin, Peter C Sprivulis and Joseph Hung

    Citation: BMC Cardiovascular Disorders 2011 11:35

    Content type: Research article

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  44. Patients with ST-elevation myocardial infarction (STEMI) treated with fibrinolysis are increasingly, and ever earlier, referred for routine coronary angiography and where feasible, undergo percutaneous coronar...

    Authors: Peter Bogaty, Kristian B Filion and James M Brophy

    Citation: BMC Cardiovascular Disorders 2011 11:34

    Content type: Research article

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  45. Growing evidence exists that living with an ICD can lead to fear and avoidance behaviour including the avoidance of physical activity. It has been suggested that psychological stress can increase the risk of s...

    Authors: Selina K Berg, Jesper H Svendsen, Ann-Dorthe Zwisler, Birthe D Pedersen, Pernille Preisler, Lone Siersbæk-Hansen, Mette B Hansen, Rune H Nielsen and Preben U Pedersen

    Citation: BMC Cardiovascular Disorders 2011 11:33

    Content type: Study protocol

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  46. This systematic review summarized recent evidence pertaining to the clinical effectiveness of 64-slice or higher computed tomography angiography (CTA) in patients with suspected coronary artery disease (CAD). ...

    Authors: Daniel C Paech and Adèle R Weston

    Citation: BMC Cardiovascular Disorders 2011 11:32

    Content type: Research article

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  47. Angiogenesis is up-regulated in myocardial ischemia. However, limited data exist assessing the value of circulating angiogenic biomarkers in predicting future incidence of acute myocardial infarction (AMI). Ou...

    Authors: Carlos Iribarren, Bruce H Phelps, Jeanne A Darbinian, Edward R McCluskey, Charles P Quesenberry, Evangelos Hytopoulos, Joseph H Vogelman and Norman Orentreich

    Citation: BMC Cardiovascular Disorders 2011 11:31

    Content type: Research article

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  48. To elucidate the mechanism by which local delivery of 3-morpholino-sydnonimine (SIN-1) affects intimal hyperplasia after percutaneous transluminal coronary angioplasty (PTCA).

    Authors: Jan Harnek, Evita Zoucas, Valéria Perez de Sá, Eva Ekblad, Anders Arner and Unne Stenram

    Citation: BMC Cardiovascular Disorders 2011 11:30

    Content type: Research article

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  49. Epidemiologic evidence suggests a heritable component to risk for sudden cardiac arrest independent of risk for myocardial infarction. Recent candidate gene association studies for community sudden cardiac arr...

    Authors: Bradley E Aouizerat, Eric Vittinghoff, Stacy L Musone, Ludmila Pawlikowska, Pui-Yan Kwok, Jeffrey E Olgin and Zian H Tseng

    Citation: BMC Cardiovascular Disorders 2011 11:29

    Content type: Research article

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  50. Socioeconomic status (SES) predicts coronary heart disease independently of the traditional risk factors included in the Framingham risk score. However, it is unknown whether changes in Framingham risk score vari...

    Authors: Peter Franks, Paul C Winters, Daniel J Tancredi and Kevin A Fiscella

    Citation: BMC Cardiovascular Disorders 2011 11:28

    Content type: Research article

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