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  1. Correspondence

    Complexity of pathomechanisms leading to diastolic heart failure in diabetes mellitus - potential field for therapeutic interventions?

    Advanced glycation end products (AGE) have been implicated in diabetes associated complications. They have been suggested as potential mediators in the progression of diabetic heart failure and as a potential ...

    Michael Schwarzer, Michel Noutsias, Frank Spillmann, P. Christian Schulze, Torsten Doenst and Carsten Tschöpe

    BMC Cardiovascular Disorders 2017 17:253

    Published on: 21 September 2017

  2. Research article

    Aqua walking as an alternative exercise modality during cardiac rehabilitation for coronary artery disease in older patients with lower extremity osteoarthritis

    The purpose of this study was to examine the effects of aqua walking (AW) on coronary artery disease (CAD) and cardiorespiratory fitness in older adults with osteoarthritis in the lower extremity and compare i...

    Jong-Young Lee, Kee-Chan Joo and Peter H. Brubaker

    BMC Cardiovascular Disorders 2017 17:252

    Published on: 21 September 2017

  3. Research article

    Financial burden of survivors of medically-managed myocardial infarction and its association with selected social determinants and quality of life in a lower middle income country

    Burden from ischemic heart disease is rising in Sri Lanka due to the demographic and epidemiological transitions. Documented literature is scarce on quality of life, financial burden and its determinants in relat...

    P. K. B. Mahesh, M. W. Gunathunga, S. Jayasinghe, S. M. Arnold, D. S. V. Mallawarachchi, S. K. Perera and U. A. D. Wijesinghe

    BMC Cardiovascular Disorders 2017 17:251

    Published on: 19 September 2017

  4. Research article

    The association of sleep disordered breathing with left ventricular remodeling in CAD patients: a cross-sectional study

    There is still insufficient knowledge on the potential effect of mild to moderate sleep-disordered breathing (SDB) that is widely prevalent, often asymptomatic, and largely undiagnosed in patients with stable ...

    Audrius Alonderis, Nijole Raskauskiene, Vaidute Gelziniene, Narseta Mickuviene and Julija Brozaitiene

    BMC Cardiovascular Disorders 2017 17:250

    Published on: 18 September 2017

  5. Research article

    Medical therapy following hospitalization for heart failure with reduced ejection fraction and association with discharge to long-term care: a cross-sectional analysis of the REasons for Geographic And Racial Differences in Stroke (REGARDS) population

    Less intensive treatment for heart failure with reduced ejection fraction (HFrEF) may be appropriate for patients in long-term care settings because of limited life expectancy, frailty, comorbidities, and emph...

    Emily B. Levitan, Melissa K. Van Dyke, Ligong Chen, Raegan W. Durant, Todd M. Brown, J. David Rhodes, Olusola Olubowale, Oluwole Muyiwa Adegbala, Meredith L. Kilgore, Justin Blackburn, Karen C. Albright and Monika M. Safford

    BMC Cardiovascular Disorders 2017 17:249

    Published on: 16 September 2017

  6. Research article

    Anemia in severe heart failure patients: does it predict prognosis?

    Anemia is highly prevalent in heart failure (HF) patients. However, the prevalence, clinical impact and prognostic factor of anemia in heart failure patients is widely varies. The aim of this study was to eval...

    Tamrat Befekadu Abebe, Eyob Alemayehu Gebreyohannes, Akshaya Srikanth Bhagavathula, Yonas Getaye Tefera and Tadesse Melaku Abegaz

    BMC Cardiovascular Disorders 2017 17:248

    Published on: 16 September 2017

  7. Research article

    Nutrition in primary and secondary prevention of cardiovascular risk in the continental and Mediterranean regions of Croatia

    The aim of this observational study was to evaluate the effect of Mediterranean and continental nutrition on cardiovascular risk in patients with acute and chronic coronary heart disease in Croatia.

    Jozica Sikic, Mira Stipcevic, Hrvoje Vrazic, Jasna Cerkez Habek, Eduard Margetic and Dario Gulin

    BMC Cardiovascular Disorders 2017 17:247

    Published on: 16 September 2017

  8. Research article

    Resting heart rate and impaired glucose regulation in middle-aged and elderly Chinese people: a cross-sectional analysis

    Elevated resting heart rate (RHR) has been reported to be associated with metabolic syndrome and type 2 diabetes. The aim of this study was to explore whether a positive relationship exists between RHR and imp...

    Zhen Yang, Weiwei Zhang, Lingfei Zhu, Ning Lin, Yixin Niu, Xiaoyong Li, Shuai Lu, Hongmei Zhang, Xuanchun Wang, Jie Wen, Guang Ning, Li Qin and Qing Su

    BMC Cardiovascular Disorders 2017 17:246

    Published on: 13 September 2017

  9. Research article

    Determination of risk factors affecting the in-hospital prognosis of patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention

    To determine the factors affecting the in-hospital prognosis of patients with acute ST segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI), and to establish its progn...

    Rui Wang, Biqi Mei, Xinlong Liao, Xia Lu, Lulu Yan, Man Lin, Yao Zhong, Yili Chen and Tianhui You

    BMC Cardiovascular Disorders 2017 17:243

    Published on: 12 September 2017

  10. Research article

    Barriers to lifestyle changes for prevention of cardiovascular disease – a survey among 40–60-year old Danes

    Elimination of modifiable risk factors including unhealthy lifestyle has the potential for prevention of 80% of cardiovascular disease cases. The present study focuses on disclosing barriers for maintaining sp...

    Jesper Bo Nielsen, Anja Leppin, Dort e Gyrd-Hansen, Dorte Ejg Jarbøl, Jens Søndergaard and Pia Veldt Larsen

    BMC Cardiovascular Disorders 2017 17:245

    Published on: 12 September 2017

  11. Case report

    One symptom, two arrhythmias: the rare and the even rarer

    Wolff-Parkinson-White (WPW) syndrome and idiopathic left ventricular tachycardia (ILVT) are rare and up to now the coexistence of both entities has rarely been reported.

    Florian Zauner, Jan-Thorben Sieweke, Stephan Hohmann, David Duncker, Christian Riehle, L. Christian Napp, Ulrike Flierl, Thorben König and Christian Veltmann

    BMC Cardiovascular Disorders 2017 17:244

    Published on: 12 September 2017

  12. Research article

    Long-term outcomes of coronary artery bypass grafting versus stent-PCI for unprotected left main disease: a meta-analysis

    Coronary artery bypass graft (CABG) surgery has traditionally represented the standard of care for left main coronary artery (LMCA) disease. However, percutaneous coronary intervention with stent implantation ...

    Salvatore De Rosa, Alberto Polimeni, Jolanda Sabatino and Ciro Indolfi

    BMC Cardiovascular Disorders 2017 17:240

    Published on: 6 September 2017

  13. Research article

    Medical and sociodemographic factors predict persistent smoking after coronary events

    Understanding the determinants of persistent smoking after a coronary event constitutes the basis of modelling interventions of smoking cessation in secondary prevention programs. We aim to identify the potent...

    Elise Sverre, Jan Erik Otterstad, Erik Gjertsen, Lars Gullestad, Einar Husebye, Toril Dammen, Torbjørn Moum and John Munkhaugen

    BMC Cardiovascular Disorders 2017 17:241

    Published on: 6 September 2017

  14. Research article

    Comparative effectiveness of rivaroxaban versus warfarin or dabigatran for the treatment of patients with non-valvular atrial fibrillation

    Rivaroxaban is an oral anticoagulant approved in the US for prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF). We determined the effectiveness and associated r...

    Faye L. Norby, Lindsay G.S. Bengtson, Pamela L. Lutsey, Lin Y. Chen, Richard F. MacLehose, Alanna M. Chamberlain, Ian Rapson and Alvaro Alonso

    BMC Cardiovascular Disorders 2017 17:238

    Published on: 6 September 2017

  15. Research article

    Adherence and outcomes to direct oral anticoagulants among patients with atrial fibrillation: findings from the veterans health administration

    The direct oral anticoagulants (DOACs) reduce the risk of stroke in moderate to high-risk patients with non-valvular atrial fibrillation (AF). Yet, concerns remain regarding its routine use in real world pract...

    Ryan T. Borne, Colin O’Donnell, Mintu P. Turakhia, Paul D. Varosy, Cynthia A. Jackevicius, Lucas N. Marzec, Frederick A. Masoudi, Paul L. Hess, Thomas M. Maddox and P. Michael Ho

    BMC Cardiovascular Disorders 2017 17:236

    Published on: 2 September 2017

  16. Research article

    The top tertile of hematocrit change during hospitalization is associated with lower risk of mortality in acute heart failure patients

    Hemoconcentration has been proposed as surrogate for changes in volume status among patients hospitalized with acute heart failure (AHF) and is associated with a favorable outcome. However, there is a dearth o...

    Haobin Zhou, Tianyu Xu, Yuli Huang, Qiong Zhan, Xingfu Huang, Qingchun Zeng and Dingli Xu

    BMC Cardiovascular Disorders 2017 17:235

    Published on: 2 September 2017

  17. Research article

    PR interval prolongation in coronary patients or risk equivalent: excess risk of ischemic stroke and vascular pathophysiological insights

    Whether PR prolongation independently predicts new-onset ischemic events of myocardial infarction and stroke was unclear. Underlying pathophysiological mechanisms of PR prolongation leading to adverse cardiova...

    Yap-Hang Chan, Jo Jo Hai, Kui-Kai Lau, Sheung-Wai Li, Chu-Pak Lau, Chung-Wah Siu, Kai-Hang Yiu and Hung-Fat Tse

    BMC Cardiovascular Disorders 2017 17:233

    Published on: 24 August 2017

  18. Research article

    Efficacy and safety of transcatheter aortic valve replacement in aortic stenosis patients at low to moderate surgical risk: a comprehensive meta-analysis

    Recently, transcatheter aortic valve replacement (TAVR) has become the procedure of choice in high surgical risk patients with aortic stenosis (AS). However, its value is still debated in operable AS cases. We...

    Ahmed Elmaraezy, Ammar Ismail, Abdelrahman Ibrahim Abushouk, Moutaz Eltoomy, Soha Saad, Ahmed Negida, Osama Mahmoud Abdelaty, Ahmed Ramadan Abdallah, Ahmed Magdy Aboelfotoh, Hossam Mahmoud Hassan, Aya Gamal Elmaraezy, Mahmoud Morsi, Farah Althaher, Moath Althaher and Ammar M. AlSafadi

    BMC Cardiovascular Disorders 2017 17:234

    Published on: 24 August 2017

  19. Research article

    2-Dimensional Speckle Tracking Echocardiography predicts severe coronary artery disease in women with normal left ventricular function: a case-control study

    Women who have coronary artery disease (CAD) often present with atypical symptoms that may lead to misdiagnosis. We assessed strain, systolic strain rate and left ventricular dyssynchrony with 2- dimensional- ...

    Ryan T. Hubbard, Maria C. Arciniegas Calle, Sergio Barros-Gomes, Joyce A. Kukuzke, Patricia A. Pellikka, Rajiv Gulati and Hector R. Villarraga

    BMC Cardiovascular Disorders 2017 17:231

    Published on: 24 August 2017

  20. Research article

    Persistence with antihypertensives in uncomplicated treatment-naïve very elderly patients: a nationwide population-based study

    Limited studies have evaluated the medication-taking behavior in very elderly hypertensive patients. The aim of this study was to evaluate the persistence and adherence with antihypertensive agents in treatmen...

    Kyung Hee Choi, Yun Mi Yu, Young-Mi Ah, Min Jung Chang and Ju-Yeun Lee

    BMC Cardiovascular Disorders 2017 17:232

    Published on: 24 August 2017

  21. Study protocol

    Does dapagliflozin regress left ventricular hypertrophy in patients with type 2 diabetes? A prospective, double-blind, randomised, placebo-controlled study

    Patients with diabetes have a two to fourfold increased risk for development of and death from cardiovascular disease [CVD]. The current oral hypoglycaemic agents result in limited reduction in this cardiovasc...

    Alexander J.M. Brown, Chim Lang, Rory McCrimmon and Allan Struthers

    BMC Cardiovascular Disorders 2017 17:229

    Published on: 23 August 2017

  22. Study protocol

    Better Indigenous Risk stratification for Cardiac Health study (BIRCH) protocol: rationale and design of a cross-sectional and prospective cohort study to identify novel cardiovascular risk indicators in Aboriginal Australian and Torres Strait Islander adults

    Of the estimated 10–11 year life expectancy gap between Indigenous (Aboriginal and Torres Strait Islander people) and non-Indigenous Australians, approximately one quarter is attributable to cardiovascular dis...

    Marc G. W. Rémond, Simon Stewart, Melinda J. Carrington, Thomas H. Marwick, Bronwyn A. Kingwell, Peter Meikle, Darren O’Brien, Nathaniel S. Marshall and Graeme P. Maguire

    BMC Cardiovascular Disorders 2017 17:228

    Published on: 23 August 2017

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