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  1. Gigantic left atrium is defined in the current literature as an excessive dilatation of the left atrium above 65mm. Chronic mitral valve disease is associated with the development of thrombus in the left atriu...

    Authors: Lucia Masarova, Jan Novak, Martin Pesl, Jiri Ondrasek, Jiri Semenka, Eva Simarova and Roman Panovsky

    Citation: BMC Cardiovascular Disorders 2020 20:86

    Content type: Case report

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  2. Sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly which has potential for spontaneous rupture into other cardiac chambers or the pericardial space (depending on its location). A ruptured SVA has a ver...

    Authors: Ata Doost, Julie-Ann Craig and Siang Yong Soh

    Citation: BMC Cardiovascular Disorders 2020 20:84

    Content type: Case report

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  3. The current guidelines recommend both repeat stenting and drug-coated balloons (DCB) for in-stent restenosis (ISR) lesions, if technically feasible. However, real-world clinical data on the interventional stra...

    Authors: Hyungdon Kook, Hyung Joon Joo, Jae Hyoung Park, Soon Jun Hong, Cheol Woong Yu and Do-Sun Lim

    Citation: BMC Cardiovascular Disorders 2020 20:83

    Content type: Research article

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  4. The effects of whole grain diet on cardiovascular risks in obese and overweight adults is not well established. Our goal was to conduct a systematic review and meta-analysis on the effect of whole grain diet o...

    Authors: Weihao Wang, Jianan Li, Xiaoxi Chen, Miao Yu, Qi Pan and Lixin Guo

    Citation: BMC Cardiovascular Disorders 2020 20:82

    Content type: Research article

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  5. Coronary microembolization (CME) has a poor prognosis, with ventricular arrhythmia being the most serious consequence. Understanding the underlying mechanisms could improve its management. We investigated the ...

    Authors: Weiwei Wang, Shuhua Ye, Lutao Zhang, Qiong Jiang, Jianhua Chen, Xuehai Chen, Feilong Zhang and Hangzhou Wu

    Citation: BMC Cardiovascular Disorders 2020 20:85

    Content type: Research article

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  6. Tanshinone IIA (TS IIA), a multi-pharmaceutical compound from traditional Chinese herb, is effective for treatment of atherothrombosis. However, the underlying mechanisms of TS IIA-mediated anti-platelet activ...

    Authors: Hua Wang, Lin Zhong, Shaohua Mi, Nianpeng Song, Wei Zhang and Ming Zhong

    Citation: BMC Cardiovascular Disorders 2020 20:81

    Content type: Research article

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  7. Contrast-induced encephalopathy (CIE) is a rare complication of cardiac catheterization; clinical manifestations include cortical blindness, seizures and focal neurological deficits. In general, recurrent epil...

    Authors: Pingping Lei, Weiping He, Quan Shi, Meiying Sun and Zhigang Sun

    Citation: BMC Cardiovascular Disorders 2020 20:79

    Content type: Case report

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  8. Percutaneous closure (LAAC) of the left atrial appendage (LAA) is an efficacious preventive procedure for patients with non-valvular atrial fibrillation (NVAF) and considerable bleeding risk. We sought to syst...

    Authors: Muhammad Ali, Angelos G. Rigopoulos, Mammad Mammadov, Abdelrahman Torky, Andrea Auer, Marios Matiakis, Elena Abate, Constantinos Bakogiannis, Stergios Tzikas, Boris Bigalke, Daniel Sedding and Michel Noutsias

    Citation: BMC Cardiovascular Disorders 2020 20:78

    Content type: Review

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  9. Identification of early signs of atherosclerosis in young adults have the potential to guide early interventions to prevent later cardiovascular disease. We therefore analyzed measures of vascular structure an...

    Authors: Paul Pettersson-Pablo, Yang Cao, Torbjörn Bäckström, Torbjörn K. Nilsson and Anita Hurtig-Wennlöf

    Citation: BMC Cardiovascular Disorders 2020 20:77

    Content type: Research article

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  10. Long-term exposure to pollution has been shown to increase risk of cardiovascular disease (CVD) and mortality, and may contribute to the increased risk of CVD among individuals with higher social risk.

    Authors: Ann Canterbury, Justin B. Echouffo-Tcheugui, Daniel Shpilsky, Aryan Aiyer, Steven E. Reis and Sebhat Erqou

    Citation: BMC Cardiovascular Disorders 2020 20:76

    Content type: Research article

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  11. Exercise training is known as a practical way to increase cardioprotection against stress, and it seems that stem cell recruitment is one of its mechanisms. The purpose of the present study was to investigate ...

    Authors: Reza Ghanimati, Hamid Rajabi, Fatemeh Ramezani, Maral Ramez, Mohsen Bapiran and Farinaz Nasirinezhad

    Citation: BMC Cardiovascular Disorders 2020 20:75

    Content type: Research article

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  12. Arrhythmogenic cardiomyopathy (AC) is one of the leading causes for sudden cardiac death (SCD). Recent studies have identified mutations in cardiac desmosomes as key players in the pathogenesis of AC. However,...

    Authors: Xiaoping Lin, Yuankun Ma, Zhejun Cai, Qiyuan Wang, Lihua Wang, Zhaoxia Huo, Dan Hu, Jian’an Wang and Meixiang Xiang

    Citation: BMC Cardiovascular Disorders 2020 20:74

    Content type: Research article

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  13. Metabolic syndrome (MS) is a disorder, characterized by clusters of cardiovascular risk factors such as central obesity, insulin resistance, dyslipidemia and hypertension. Patients with MS may have a higher pl...

    Authors: Xu Yang, Wei Luo, Shan Han, Lei Zha, Jing Zhang, Xiaowei Li, Hui Zhao, Shuo Liang and Ru Zhao

    Citation: BMC Cardiovascular Disorders 2020 20:73

    Content type: Research article

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  14. Adherence to medication regimens is essential for preventing and reducing adverse outcomes among patients with coronary artery disease (CAD). Greater understanding of the relation between negative illness perc...

    Authors: Patricia Thomson, Gordon F. Rushworth, Federico Andreis, Neil J. Angus, Andrea R. Mohan and Stephen J. Leslie

    Citation: BMC Cardiovascular Disorders 2020 20:71

    Content type: Research article

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  15. Prediction of major adverse cardiovascular events (MACEs) may offer great benefits for patients with coronary artery disease (CAD). Von Willebrand factor (vWF) is stored in endothelial cells and released into ...

    Authors: Mengge Fan, Xia Wang, Xun Peng, Shuo Feng, Junyu Zhao, Lin Liao, Yong Zhang, Yinglong Hou and Ju Liu

    Citation: BMC Cardiovascular Disorders 2020 20:72

    Content type: Research article

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  16. “After publication of our article [1] we became aware that we had not obtained permission to reproduce the questions from the eight-item Morisky’s Medication Adherence Scale.

    Authors: Rasaq Adisa, Olumide Ayodeji Ilesanmi and Titilayo Oyelola Fakeye

    Citation: BMC Cardiovascular Disorders 2020 20:68

    Content type: Correction

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    The original article was published in BMC Cardiovascular Disorders 2018 18:194

  17. Cardiac tamponade is a rare but serious complication of Takotsubo cardiomyopathy (TC). Two cases of cardiac tamponade subsequent to TC have been reported. The pericardial effusion in these cases was hemorrhagi...

    Authors: Yuta Nagamori, Takuto Hamaoka, Hisayoshi Murai, Shinichiro Takashima, Takeshi Kato, Soichiro Usui, Kenji Sakata, Hiroshi Furusho, Masaaki Kawashiri and Masayuki Takamura

    Citation: BMC Cardiovascular Disorders 2020 20:67

    Content type: Case report

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  18. Tobacco smoke is one of the most significant risk factors for cardiovascular diseases and damages in the myocardial tissue directly. Cardiac magnetic resonance (CMR) has been used and is a promising tool to ev...

    Authors: Ana Natália Ribeiro Batista, Thais Garcia, Estefânia Aparecida Thomé Franco, Paula Schmidt Azevedo, Mauricio Fregonesi Barbosa, Leonardo Antonio Mamede Zornoff, Marcos Ferreira Minicucci, Sergio Alberto Rupp de Paiva, José William Zucchi, Irma de Godoy and Suzana Erico Tanni

    Citation: BMC Cardiovascular Disorders 2020 20:66

    Content type: Research article

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  19. The performance of drug-coated balloons (DCBs) in femoropopliteal interventions has been proven through randomized trials in short lesions and lesions with relatively low proportion of occlusions. There is lim...

    Authors: Zhichao Lai, Xin Zhang, Jiang Shao, Kang Li, Lijing Fang, Leyin Xu, Xiaoxi Yu, Jingjing Wang, Xiu Liu, Jinsong Lei and Bao Liu

    Citation: BMC Cardiovascular Disorders 2020 20:65

    Content type: Research article

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  20. The relative importance of lifestyle, medical and psychosocial factors on the risk of recurrent major cardiovascular (CV) events (MACE) in coronary patients’ needs to be identified. The main objective of this ...

    Authors: E. Sverre, K. Peersen, H. Weedon-Fekjær, J. Perk, E. Gjertsen, E. Husebye, L. Gullestad, T. Dammen, J. E. Otterstad and J. Munkhaugen

    Citation: BMC Cardiovascular Disorders 2020 20:61

    Content type: Research article

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  21. Malignant ventricular arrhythmia (VA) is the most common cause of death associated with acute myocardial infarction (MI). Recent studies have revealed direct involvement of the paraventricular nucleus (PVN) in...

    Authors: Meng Gao, Dechun Yin, Jugang Chen and Xiufen Qu

    Citation: BMC Cardiovascular Disorders 2020 20:60

    Content type: Research article

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  22. According to the World Health Organization, cardiovascular diseases (CVDs) are the leading non-communicable cause of death. Awareness of the individual risk profile is crucial to implement a healthy lifestyle ...

    Authors: Benoît Bernar, Nina Gande, Katharina A. Stock, Anna Staudt, Raimund Pechlaner, Ralf Geiger, Andrea Griesmacher, Stefan Kiechl, Michael Knoflach and Ursula Kiechl-Kohlendorfer

    Citation: BMC Cardiovascular Disorders 2020 20:59

    Content type: Study protocol

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  23. Several inherited cardiac diseases may lead to sudden cardiac death (SCD) a devastating event in the families. It is crucial to establish a post mortem diagnosis to facilitate relevant work-up and treatment of...

    Authors: Puriya Daniel Yazdanfard, Alex Hørby Christensen, Jacob Tfelt-Hansen, Henning Bundgaard and Bo Gregers Winkel

    Citation: BMC Cardiovascular Disorders 2020 20:58

    Content type: Research article

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  24. Although the Melanocortin-4 Receptor (MC4R) gene rs17782313 C/T has been consistently related to obesity risk, the interaction between MC4R polymorphism and diet quality indices on cardio-metabolic risk factor...

    Authors: Mahdieh Khodarahmi, Houman Kahroba, Mohammad Asghari Jafarabadi, Mehran Mesgari-Abbasi and Mahdieh Abbasalizad Farhangi

    Citation: BMC Cardiovascular Disorders 2020 20:57

    Content type: Research article

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  25. Autophagy plays a crucial role in the pathological process of cardiovascular diseases. However, little is known about the pathological mechanism underlying autophagy regulation in dilated cardiomyopathy (DCM).

    Authors: Bo Jin, Haiming Shi, Jun Zhu, Bangwei Wu and Quzhen Geshang

    Citation: BMC Cardiovascular Disorders 2020 20:56

    Content type: Research article

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  26. The optimal duration of oral anticoagulant therapy for patients with venous thromboembolism (VTE) remains highly uncertain in clinical practice. It is essential to accurately assess the effect of anticoagulant...

    Authors: Wei Wang, Yang Su, Chunyan Wu, Yuxi Sun, Neng Dai, Wei Chen, Jie Zhang, Yawei Xu, Ralph G. Brindis, Dachun Xu and Jue Li

    Citation: BMC Cardiovascular Disorders 2020 20:53

    Content type: Research article

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  27. The etiology of Takayasu arteritis (TA) is unknown; however, a possible relationship between streptococcal infection and TA has been proposed. This study aimed to identify the clinical features and cardiac val...

    Authors: Lili Pan, Juan Du, Junming Zhu, Zhiyu Qiao, Yanlong Ren, Xinsheng Huang, Shichao Guo and Na Gao

    Citation: BMC Cardiovascular Disorders 2020 20:52

    Content type: Research article

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  28. Aortic valve regurgitation (AR) results in left ventricle (LV) volume overload (VO) leading to its dilation and hypertrophy (H). We study a rat model of severe AR induced by puncturing one or two leaflets usin...

    Authors: Elisabeth Walsh-Wilkinson, Marie-Claude Drolet, Marie Arsenault and Jacques Couet

    Citation: BMC Cardiovascular Disorders 2020 20:51

    Content type: Research article

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  29. Previous studies demonstrated impaired lipid metabolism and augmented aerobic glycolysis in AF. The authors aimed to investigate whether the use of metformin, an AMPK activator, could reverse this metabolic re...

    Authors: Yaozhong Liu, Fan Bai, Na Liu, Baojian Zhang, Fen Qin, Tao Tu, Biao Li, Jiayi Li, Yingxu Ma, Feifan Ouyang and Qiming Liu

    Citation: BMC Cardiovascular Disorders 2020 20:50

    Content type: Research article

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  30. Three-dimensional electroanatomic mapping systems have demonstrated a significant reduction in radiation exposure during radiofrequency catheter ablation procedures. We aimed to investigate the safety, feasibi...

    Authors: Guangzhi Chen, Yan Wang, Riccardo Proietti, Xunzhang Wang, Feifan Ouyang, Chang Sheng Ma, Rong Hui Yu, Chunxia Zhao, Kezhong Ma, Jie Qiu, Qigong Liu and Dao Wen Wang

    Citation: BMC Cardiovascular Disorders 2020 20:48

    Content type: Research article

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  31. Cardiac surgery for prosthetic valve endocarditis (PVE) is associated with substantial mortality. We aimed to analyze 30-day and 1-year outcome in patients undergoing surgery for PVE and sought to identify pre...

    Authors: Carolyn Weber, Parwis B. Rahmanian, Melanie Nitsche, Asmae Gassa, Kaveh Eghbalzadeh, Stefanie Hamacher, Julia Merkle, Antje-Christin Deppe, Anton Sabashnikov, Elmar W. Kuhn, Oliver J. Liakopoulos and Thorsten Wahlers

    Citation: BMC Cardiovascular Disorders 2020 20:47

    Content type: Research article

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  32. The ‘My Experience of Taking Medicines’ (MYMEDS) questionnaire is a self-reporting tool for identifying modifiable adherence barriers among individuals prescribed post-myocardial infarction (MI) secondary prev...

    Authors: Rani Khatib, Nasrin Patel and Alistair S. Hall

    Citation: BMC Cardiovascular Disorders 2020 20:46

    Content type: Research article

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  33. To investigate the influence of hyperhomocysteinemia (HHcy) and metabolic syndrome (MetS) on left ventricular hypertrophy (LVH) in residents in rural Northeast China.

    Authors: Shasha Yu, Yintao Chen, Hongmei Yang, Xiaofan Guo, Liqiang Zheng and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2020 20:44

    Content type: Research article

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  34. The current diagnostic methods and treatments still fail to lower the incidence of anthracycline-induced cardiotoxicity effectively. In this study, we aimed to (1) analyze the cardiotoxicity-related genes afte...

    Authors: Wang Yadi, Chen Shurui, Zhang Tong, Chen Suxian, Tong Qing and He Dongning

    Citation: BMC Cardiovascular Disorders 2020 20:43

    Content type: Research article

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  35. We evaluated adherence to dosing criteria for patients with atrial fibrillation (AF) taking dabigatran or rivaroxaban and the impact of off-label dosing on thromboembolic and bleeding risk.

    Authors: Alexandros Briasoulis, Yubo Gao, Chakradhari Inampudi, Paulino Alvarez, Rabea Asleh, Elizabeth Chrischilles, Enrique C. Leira and Mary Vaughan-Sarrazin

    Citation: BMC Cardiovascular Disorders 2020 20:42

    Content type: Research article

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  36. Hypertension is a major cardiovascular illness worldwide with many underlying causes. The role of trace elements selenium, copper, and zinc in hypertension is uncertain. The objective of this study was to eval...

    Authors: Mrigendra M. Bastola, Craig Locatis, Richard Maisiak and Paul Fontelo

    Citation: BMC Cardiovascular Disorders 2020 20:45

    Content type: Research article

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  37. Endothelial dysfunction may play a key role in non-obstructive coronary artery atherosclerosis. Our study aimed to evaluate the vascular endothelial function and its influencing factors in patients with non-ob...

    Authors: Yin-Ping Li, Zhen-Xing Fan, Jing Gao, Xi-Peng Sun, Guo-Hua Zhu, Ying-Hua Zhang, Jin Si, Xue-Bing Zuo, Zhi Liu, Qi Hua and Jing Li

    Citation: BMC Cardiovascular Disorders 2020 20:40

    Content type: Research article

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  38. Although mineral metabolism disorder influences cardiac valvular calcification (CVC), few previous studies have examined the effects of non-calcium-containing and calcium-containing phosphate binders on CVC in...

    Authors: Kentaro Watanabe, Hideki Fujii, Keiji Kono, Shunsuke Goto and Shinichi Nishi

    Citation: BMC Cardiovascular Disorders 2020 20:39

    Content type: Research article

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  39. Patients with cancer admitted for an acute coronary syndrome (ACS) and/or percutaneous coronary intervention (PCI) represent a growing and high-risk population. The influence of co-existing cancer on mortality...

    Authors: Vincent Roule, Laurine Verdier, Katrien Blanchart, Pierre Ardouin, Adrien Lemaitre, Mathieu Bignon, Rémi Sabatier, Joachim Alexandre and Farzin Beygui

    Citation: BMC Cardiovascular Disorders 2020 20:38

    Content type: Research article

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  40. The combined effects of diabetes mellitus (DM), admission plasma glucose (APG), and glycated hemoglobin (HbA1c) levels on predicting long-term clinical outcomes in patients with ST-segment elevation myocardial...

    Authors: Yan Li, Xiaowen Li, Yinhua Zhang, Leimin Zhang, Qingqing Wu, Zhaorun Bai, Jin Si, Xuebing Zuo, Ning Shi, Jing Li and Xi Chu

    Citation: BMC Cardiovascular Disorders 2020 20:36

    Content type: Research article

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  41. Although, in-part through an impact on left ventricular mass (LVM), resistin (an adipokine) may contribute to heart failure, whether this is explained by the adverse effects of resistin on aortic stiffness and...

    Authors: Glenda Norman, Gavin R. Norton, Vernice Peterson, Monica Gomes, Carlos D. Libhaber, Pinhas Sareli and Angela J. Woodiwiss

    Citation: BMC Cardiovascular Disorders 2020 20:35

    Content type: Research article

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  42. Aortic stenosis (AS) causes left ventricular (LV) pressure overload, leading to adverse LV remodeling and dysfunction. Identifying early subclinical markers of LV dysfunction in patients with significant AS is...

    Authors: Xiaojun Bi, Darwin F. Yeung, Husam M. Salah, Maria C. Arciniegas Calle, Jeremy J. Thaden, Lara F. Nhola, Hartzell V. Schaff, Sorin V. Pislaru, Patricia A. Pellikka, Alberto Pochettino, Kevin L. Greason, Vuyisile T. Nkomo and Hector R. Villarraga

    Citation: BMC Cardiovascular Disorders 2020 20:33

    Content type: Research article

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  43. Atrial fibrillation with symptomatic bradycardia, higher grade atrioventricular block, and sinus node disease are all common indications for permanent pacemaker implantation. The most frequent causes of sinus ...

    Authors: Jörg Reifart, Marlene Tschernatsch, Christian W. Hamm, Johannes Sperzel and Andreas Hain

    Citation: BMC Cardiovascular Disorders 2020 20:30

    Content type: Case report

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  44. The Starr-Edwards ball valve prosthesis was successfully introduced in 1961–62 and largely used for aortic and mitral valve replacement. Even if Starr-Edwards valves have been widely replaced in clinical pract...

    Authors: Andrea Ponsiglione, Gianrico Spagnuolo, Gabriella Spagnuolo, Arnaldo Stanzione, Carmela Nappi, Serena Dell’Aversana, Antonio Spagnuolo, Alberto Cuocolo and Massimo Imbriaco

    Citation: BMC Cardiovascular Disorders 2020 20:37

    Content type: Case report

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  45. The gut microbiome plays an important role in various cardiovascular diseases, such as atherosclerosis and hypertension, which are associated with abdominal aortic aneurysms (AAAs).

    Authors: Jiahe Xie, Weiling Lu, Lintao Zhong, Yuhua Hu, Qingrui Li, Rongming Ding, Zhonggao Zhong, Ziyou Liu, Hai Xiao, Dongming Xie, Guofu Zheng, Bo Ye, Yiming Zhong and Zuheng Liu

    Citation: BMC Cardiovascular Disorders 2020 20:32

    Content type: Research article

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  46. This study investigated the value of layer-specific strain analysis by two-dimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in mainten...

    Authors: Chang Liu, Zi-Ning Yan, Li Fan, Jun Huang, Dan Shen and Xiang-Ting Song

    Citation: BMC Cardiovascular Disorders 2020 20:1324

    Content type: Research article

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