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  1. Leadless pacemaker has been acknowledged as a promising pacing strategy to prevent pocket and lead-related complications. Although rare, cardiac perforation remains a major safety concern for implantation of M...

    Authors: Xueying Chen, Jingfeng Wang, Yixiu Liang, Yangang Su and Junbo Ge

    Citation: BMC Cardiovascular Disorders 2021 21:461

    Content type: Case report

    Published on:

  2. Preoperative coronary artery disease risk factors (CADRFs) distribution and pattern may also have an important role in determining major adverse cardiovascular events (MACEs). In this study, we aimed to evalua...

    Authors: Babak Sattartabar, Ali Ajam, Mina Pashang, Arash Jalali, Saeed Sadeghian, Hamideh Mortazavi, Soheil Mansourian, Jamshid Bagheri, Abbas-Ali Karimi and Kaveh Hosseini

    Citation: BMC Cardiovascular Disorders 2021 21:460

    Content type: Research

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  3. Women do not participate in cardiac rehabilitation (CR) to the same degree as men; women-focused CR may address this. This systematic review investigated the: (1) nature, (2) availability, as well as (3a) util...

    Authors: Taslima Mamataz, Gabriela L. M. Ghisi, Maureen Pakosh and Sherry L. Grace

    Citation: BMC Cardiovascular Disorders 2021 21:459

    Content type: Research

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  4. There has not been a well-accepted prognostic model to predict the mortality of aortic aneurysm patients in intensive care unit after open surgery repair. Otherwise, our previous study found that anion gap was...

    Authors: Yijing Gao, Zilin Hong, Runnan Shen, Shiran Zhang, Guochang You, Jie Chen, Xushun Guo, Senyi Peng and Kai Huang

    Citation: BMC Cardiovascular Disorders 2021 21:458

    Content type: Research

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  5. Spinal artery ischemia (SCI) events can result from over coverage of the descending thoracic aorta with a coated stent during Thoracic Endovascular Aortic Repair (TEVAR). The aim of this study was to determine...

    Authors: Xunqiang Liu, Wenkai Ji, Min Tian, Huanjun Chen, Cuihong Li, Liqiong Zhang, Ying Yang, Jifeng Wang, Min Ji, Chunxin Yang, Enshuai Zhu, Lei Cong, Xili Zhang, Xiaona Zhou, Hailong Liu, Jiaping Wang…

    Citation: BMC Cardiovascular Disorders 2021 21:457

    Content type: Research

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  6. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) lower cardiovascular events in type 2 diabetes mellitus (T2DM) patients, although the mechanisms underlying these benefits are not clearly understood. Our aim...

    Authors: Sergio Gamaza-Chulián, Enrique Díaz-Retamino, Fátima González-Testón, José Carlos Gaitero, María José Castillo, Raquel Alfaro, Elías Rodríguez, Eva González-Caballero and Antonio Martín-Santana

    Citation: BMC Cardiovascular Disorders 2021 21:456

    Content type: Research article

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  7. To investigate the relationship between ST-segment resolution (STR) and myocardial scar thickness after percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STE...

    Authors: Qian Dong, Xuesong Wen, Guanglei Chang, Rui Xia, Sihang Wang, Yunjing Yang, Yi Tao, Dongying Zhang and Shu Qin

    Citation: BMC Cardiovascular Disorders 2021 21:455

    Content type: Research

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  8. Platelet-to-lymphocyte ratio (PLR) is an inflammation index suggested to have the prognostic capability in heart failure (HF). We sought to investigate the association of PLR with cardiovascular disease (CVD) ...

    Authors: Maryam Heidarpour, Sepideh Bashiri, Mehrbod Vakhshoori, Kiyan Heshmat-Ghahdarijani, Farbod Khanizadeh, Shaghayegh Ferdowsian and Davood Shafie

    Citation: BMC Cardiovascular Disorders 2021 21:454

    Content type: Research

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  9. Valvular heart disease (VHD) in non-valvular atrial fibrillation (AF) is a puzzling clinical entity. The aim of this study was to evaluate the prognostic effect of significant VHD (sVHD) among patients with no...

    Authors: Athanasios Samaras, Eleni Vrana, Anastasios Kartas, Dimitrios V. Moysidis, Andreas S. Papazoglou, Ioannis Doundoulakis, George Fotos, Georgios Rampidis, Dimitrios G. Tsalikakis, Georgios Efthimiadis, Haralambos Karvounis, Apostolos Tzikas and George Giannakoulas

    Citation: BMC Cardiovascular Disorders 2021 21:453

    Content type: Research

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  10. Light-chain cardiac amyloidosis (AL-CA) has been highly valued in developed countries, but in developing countries, the recognition and diagnosis of this condition is still limited. There are currently few rep...

    Authors: Zhijian Wu, Muzheng Li, Tudahun Ilyas, Wei Li, Mu Zeng, Fang Li, Yanxia Liu, Mingxian Chen, Yaqin Chen, Qingyi Zhu, Nenghua Qi, Qiming Liu and Jianjun Tang

    Citation: BMC Cardiovascular Disorders 2021 21:452

    Content type: Research

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  11. Delayed coronary artery occlusion (CAO) is a rare but fatal complication after transcatheter aortic valve replacement, chimney stenting is the standard technique for established CAO or impending CAO.

    Authors: Hui Li, Wenduo Zhang, Bo Xia, Fucheng Sun, Jiefu Yang and Huiping Zhang

    Citation: BMC Cardiovascular Disorders 2021 21:451

    Content type: Case report

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  12. To investigate changes in tricuspid annulus (TA) and tricuspid valve (TV) morphology among chronic thromboembolic pulmonary hypertension (CTEPH) patients before and 12 months after pulmonary thromboendarterect...

    Authors: Christian Alcaraz Frederiksen, Farhad Waziri, Steffen Ringgaard, Søren Mellemkjær, Tor Skibsted Clemmensen, Vibeke Elisabeth Hjortdal, Sten Lyager Nielsen and Steen Hvitfeldt Poulsen

    Citation: BMC Cardiovascular Disorders 2021 21:450

    Content type: Research article

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  13. Unruptured sinus of valsalva aneurysm (SOVA) are typically asymptomatic, and hence can be easily ignored. Ruptured sinus of valsalva aneurysm (RSOVA) usually protrude into the right atrium or ventricular. Howe...

    Authors: Guang Ying Zhuo, Pei Yong Zhang, Li Luo, Qian Tang and Tao Xiang

    Citation: BMC Cardiovascular Disorders 2021 21:449

    Content type: Case report

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  14. Vascular endothelial cell apoptosis is the leading risk factor of atherosclerosis (AS). The purpose of our study was to use a new generation high-throughput transcription factor (TF) detection method to identi...

    Authors: Mangyuan Wang, Fen Liu, Binbin Fang, Qiang Huo and Yining Yang

    Citation: BMC Cardiovascular Disorders 2021 21:448

    Content type: Research article

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  15. High normal resting pCO2 is a risk factor for salt sensitivity of blood pressure (BP) in normotensive humans and has been associated with higher resting systolic BP in postmenopausal women. To date, however, no k...

    Authors: David E. Anderson, Alexis N. Reeves, Wolf E. Mehling and Margaret A. Chesney

    Citation: BMC Cardiovascular Disorders 2021 21:447

    Content type: Research

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  16. Coronary artery disease (CAD) is a common cardiac disease with high morbidity and mortality, and triple-vessel disease (TVD) is a severe type of CAD. This study investigated risk factors for revascularization ...

    Authors: MengYing Zeng, XiaoWei Yan and Wei Wu

    Citation: BMC Cardiovascular Disorders 2021 21:446

    Content type: Research

    Published on:

  17. Catheter ablation is an established therapy for atrial fibrillation but is limited by recurrence; efforts have been made to identify biomarkers that predict recurrence. We investigated the effect of baseline N...

    Authors: Willy Weng, Rajin Choudhury, John Sapp, Anthony Tang, Jeff S. Healey, Isabelle Nault, Lena Rivard, Isabelle Greiss, Jordan Bernick and Ratika Parkash

    Citation: BMC Cardiovascular Disorders 2021 21:445

    Content type: Research

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  18. Effective prevention and treatment of hypertension is one of the most potential interventions in terms of preventing cardiovascular deaths and disabilities. However, the treatment control is often poor. This m...

    Authors: Aapo Tahkola, Päivi Korhonen, Hannu Kautiainen, Teemu Niiranen and Pekka Mäntyselkä

    Citation: BMC Cardiovascular Disorders 2021 21:444

    Content type: Research

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  20. Thromboembolic events are the most serious complication of atrial fibrillation (AF), and the left atrial appendage (LAA) is the most important site of thrombosis in patients with AF. During the period of COVID...

    Authors: Lei Chen, Changjiang Xu, Wensu Chen and Chaoqun Zhang

    Citation: BMC Cardiovascular Disorders 2021 21:442

    Content type: Research

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  21. Previous clinical studies have suggested an effect of gender on outcome after out-of-hospital cardiac arrest, but the results are conflicting and there is no uniform agreement regarding gender differences in s...

    Authors: Jianjie Wang, Jingru Li, Bihua Chen, Yiming Shen, Juan Wang, Kaifa Wang, Changlin Yin and Yongqin Li

    Citation: BMC Cardiovascular Disorders 2021 21:441

    Content type: Research

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  22. MiR-92a-3p and oxidative stress are associated with catheter-related thrombosis (CRT). As a kind of physical intervention, resistance exercise can effectively promote blood circulation. In this study, we inves...

    Authors: Cui Wen, Yanping Ying, Huihan Zhao, Qingjuan Jiang, Xiao Gan, Yan Wei, Jiani Wei and Xinxin Huang

    Citation: BMC Cardiovascular Disorders 2021 21:440

    Content type: Research

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  23. To evaluate the predictive value of CHADS2 and CHA2DS2-VASc scores for coronary artery lesions and in-hospital prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI).

    Authors: Xiaoli Li, Zhen Zeng, Xinchun Yang and Hongjiang Wang

    Citation: BMC Cardiovascular Disorders 2021 21:439

    Content type: Research

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  24. The risk factors of in-stent restenosis (ISR) among coronary artery disease (CAD) patients with syphilis after percutaneous coronary intervention (PCI) are not fully understood. Therefore, this study aimed to ...

    Authors: Ling Zhang, Yu Wang, Zhe Zhang, Hongyuan Liang, Liang Wu, Liang Ni, Guiju Gao, Di Yang, Hongxin Zhao and Jiang Xiao

    Citation: BMC Cardiovascular Disorders 2021 21:438

    Content type: Research

    Published on:

  26. The cellular adhesion pathway has been suggested as playing an important role in the pathogenesis of atrial fibrillation (AF). However, prior studies that have investigated the role of adhesion pathway protein...

    Authors: Israel J. Mendez, Sheila M. Manemann, Elizabeth J. Bell, Nicholas B. Larson, Paul A. Decker, Marco A. Guerrero, Naomi Q. Hanson, Susan R. Heckbert, James S. Pankow, Michael Y. Tsai and Suzette J. Bielinski

    Citation: BMC Cardiovascular Disorders 2021 21:436

    Content type: Research

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  27. This study aimed to develop and validate a nomogram to predict probability of in-stent restenosis (ISR) in patients undergoing percutaneous coronary intervention (PCI).

    Authors: Wenbo He, Changwu Xu, Xiaoying Wang, Jiyong Lei, Qinfang Qiu, Yingying Hu and Da Luo

    Citation: BMC Cardiovascular Disorders 2021 21:435

    Content type: Research

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  28. The coronavirus-disease 2019 (COVID-19) pandemic imposed an unprecedented burden on the provision of cardiac surgical services. The reallocation of workforce and resources necessitated the postponement of elec...

    Authors: Dimitrios Vlastos, Ishaansinh Chauhan, Kwabena Mensah, Maria Cannoletta, Athanasios Asonitis, Ahmed Elfadil, Mario Petrou, Anthony De Souza, Cesare Quarto, Sunil K. Bhudia, Ulrich Rosendahl, John Pepper and George Asimakopoulos

    Citation: BMC Cardiovascular Disorders 2021 21:434

    Content type: Research

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  29. A high level of total cholesterol is associated with several lipid metabolism disorders, including atherosclerosis and cardiovascular diseases. ATP-binding cassette (ABC) transporter A1 (ABCA1) and miR-33-5p p...

    Authors: Qiong Xie, Jianqiang Peng, Ying Guo and Feng Li

    Citation: BMC Cardiovascular Disorders 2021 21:433

    Content type: Research

    Published on:

  30. Considering the inconsistencies in the cardiovascular effects of dietary acid load and the impact of dietary acidity on the acid–base homeostasis within the body, we aimed to assess the association of dietary ...

    Authors: Parvin Mirmiran, Zeinab Houshialsadat, Zahra Bahadoran, Sajjad Khalili‑Moghadam, Mohammad Karim Shahrzad and Fereidoun Azizi

    Citation: BMC Cardiovascular Disorders 2021 21:432

    Content type: Research

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  31. Hyperlactatemia may be caused by increased production due to tissue hypoxia or non-hypoxia. The aim of this study was first to identify risk factors for postoperative hyperlactatemia (POHL) after Stanford type...

    Authors: Su Wang, Dashuai Wang, Xiaofan Huang, Hongfei Wang, Sheng Le, Jinnong Zhang and Xinling Du

    Citation: BMC Cardiovascular Disorders 2021 21:431

    Content type: Research

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  32. Dyspnea is a common symptom in patients presenting to the emergency department. It has a variety of causes that range from non-urgent to life-threatening. One episode of dyspnea in a healthy young person is ea...

    Authors: Sung Eun Lee, Seung-Hyun Yoon, Hyo Jung Kang and Jung Hwan Ahn

    Citation: BMC Cardiovascular Disorders 2021 21:430

    Content type: Case report

    Published on:

  33. Homocysteine (Hcy) is considered to be a risk factor for cardiovascular and cerebrovascular diseases. Few studies have evaluated the distribution of Hcy on a large-scale health examination. Accordingly, this s...

    Authors: Fang Bao, Ming Cui, Xiuying Shi, Shaoqing Ju and Hui Cong

    Citation: BMC Cardiovascular Disorders 2021 21:429

    Content type: Research article

    Published on:

  34. Mycotic aortic aneurysm is a rare and potentially life-threatening lesion, and endovascular repair has become increasingly accepted for intervention. Fenestrated endografts are available options to treat aneur...

    Authors: Siting Li, Mengyin Chen, Yuehong Zheng, Zhili Liu and Rong Zeng

    Citation: BMC Cardiovascular Disorders 2021 21:428

    Content type: Case report

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  35. Acute perimyocarditis is a rare extra-intestinal manifestation in Crohn’s disease which required multimodality imaging to confirm the diagnosis. Here we present a case of acute perimyocarditis as the first pre...

    Authors: Hawani Sasmaya Prameswari, Iswaree Devi Balakrishnan, Chun Yuan Khoo, Loon Yee Teo, Lihua Laura Chan and Choon Ta Ng

    Citation: BMC Cardiovascular Disorders 2021 21:427

    Content type: Case report

    Published on:

  36. Cannabis is increasingly used for therapeutic purpose. However, its safety profile is not well known. This study assessed the risk of cardiovascular-related emergency department (ED) visit and hospitalization ...

    Authors: Arsene Zongo, Cerina Lee, Jason R. B. Dyck, Jihane El-Mourad, Elaine Hyshka, John G. Hanlon and Dean T. Eurich

    Citation: BMC Cardiovascular Disorders 2021 21:426

    Content type: Research

    Published on:

  37. Accelerated idioventricular rhythm (AIVR) is often transient, considered benign and requires no treatment. This observational study aims to investigate the clinical manifestations, treatment, and prognosis of ...

    Authors: Lan Wang, Hailei Liu, Chao Zhu, Kai Gu, Gang Yang, Hongwu Chen, Weizhu Ju, Mingfang Li, Fengxiang Zhang, Bing Yang, Dao Wu Wang and Minglong Chen

    Citation: BMC Cardiovascular Disorders 2021 21:425

    Content type: Research

    Published on:

  39. This study sought to describe the epidemiology of anticoagulation therapy for critically ill patients with new-onset atrial fibrillation (NOAF) according to CHA2DS2-VASc and HAS-BLED scores and to assess the e...

    Authors: Masaaki Sakuraya, Takuo Yoshida, Yusuke Sasabuchi, Shodai Yoshihiro and Shigehiko Uchino

    Citation: BMC Cardiovascular Disorders 2021 21:423

    Content type: Research article

    Published on:

  40. Inflammation plays a key role in the development of atherosclerosis and in the pathogenesis of acute coronary syndrome (ACS). Leukocytes and leukocytes ratios were recognized as inflammatory markers in predict...

    Authors: Ahmed Mohammed Shumilah, Arwa Mohammed Othman and Anwar Kasim Al-Madhagi

    Citation: BMC Cardiovascular Disorders 2021 21:422

    Content type: Research

    Published on:

  41. Although obstructive sleep apnoea (OSA) is prevalent among patients with aortic dissection, its prognostic impact is not yet determined in patients undergoing major vascular surgery. We aimed to investigate th...

    Authors: Xin Xi, Yu Chen, Wei-Guo Ma, Jiang Xie, Yong-Min Liu, Jun-Ming Zhu, Ming Gong, Guang-Fa Zhu and Li-Zhong Sun

    Citation: BMC Cardiovascular Disorders 2021 21:421

    Content type: Research article

    Published on:

  42. Malnutrition in early life may affect health in later life. The associations between malnutrition and serum uric acid (SUA) and hypertension were inconsistent. The present study aimed to investigate the indivi...

    Authors: Lin Zhang, Liu Yang, Congzhi Wang, Ting Yuan, Dongmei Zhang, Huanhuan Wei, Jing Li, Yunxiao Lei, Lu Sun, Xiaoping Li, Ying Hua, Hengying Che and Yuanzhen Li

    Citation: BMC Cardiovascular Disorders 2021 21:420

    Content type: Research

    Published on:

  43. Epidemiological studies indicate increased prevalence of cardiovascular disease (CVD) among military personnel. Accordingly, identification of at-risk individuals and lifestyle modification such as improving d...

    Authors: Karim Parastouei, Mojtaba Sepandi and Eslam Eskandari

    Citation: BMC Cardiovascular Disorders 2021 21:419

    Content type: Research

    Published on:

  44. Postoperative atrial fibrillation (POAF) is the most common cardiac dysrhythmia to occur after coronary artery bypass grafting (CABG). However, the risk factors for new-onset POAF after CABG during the periope...

    Authors: Eun Ji Seo, Joonhwa Hong, Hyeon-Ju Lee and Youn-Jung Son

    Citation: BMC Cardiovascular Disorders 2021 21:418

    Content type: Research article

    Published on:

  45. Cardiovascular disease (CVD) is a common comorbidity associated with chronic obstructive pulmonary disease (COPD), but few studies have been conducted to identify CVD risk in COPD patients. This study was to d...

    Authors: Yun Shi, Jing Zhang and Yingshuo Huang

    Citation: BMC Cardiovascular Disorders 2021 21:417

    Content type: Research

    Published on:

  46. To explore the characteristics of myocardial textures on coronary computed tomography angiography (CCTA) images in patients with coronary atherosclerotic heart disease, a classification model was established, ...

    Authors: Hengyu Zhao, Lijie Yuan, Zhishang Chen, Yuting Liao and Jiangzhou Lin

    Citation: BMC Cardiovascular Disorders 2021 21:416

    Content type: Research article

    Published on:

  47. Tinnitus is a common auditory symptom. Dysfunction in the autonomic nervous system (ANS) is an essential part of the etiopathogenesis of tinnitus. ANS regulates heart rate and heart rhythm and can lead to vent...

    Authors: Hakan Kaya, Arif Suner, Mehtap Koparal, S. Cem Yucetas and Safiye Kafadar

    Citation: BMC Cardiovascular Disorders 2021 21:415

    Content type: Research

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  48. This study aimed to investigate the clinical features and prognosis of diabetes and myocardial injury in patients admitted to the emergency department.

    Authors: Gil Bonet, Anna Carrasquer, Óscar M. Peiró, Raul Sanchez-Gimenez, Nisha Lal-Trehan, Victor del-Moral-Ronda, Isabel Fort-Gallifa and Alfredo Bardají

    Citation: BMC Cardiovascular Disorders 2021 21:414

    Content type: Research article

    Published on:

  49. The bicuspid aortic valve (BAV) is prone to ascending aortic dilatation (AAD) involving both the tubular segment and the aortic root. The genetic factor was proposed as one of the most important mechanisms for...

    Authors: Mingjia Ma, Zongzhe Li, Mohamed Abdulkadir Mohamed, Ligang Liu and Xiang Wei

    Citation: BMC Cardiovascular Disorders 2021 21:413

    Content type: Research

    Published on:

  50. Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain.

    Authors: Ali Sheikhy, Aida Fallahzadeh, Saeed Sadeghian, Khalil Forouzannia, Jamshid Bagheri, Abbas Salehi-Omran, Masih Tajdini, Arash Jalali, Mina Pashang and Kaveh Hosseini

    Citation: BMC Cardiovascular Disorders 2021 21:412

    Content type: Research

    Published on:

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