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  1. Ischemic heart disease (IHD) is the leading cause of premature death which poses public health challenges worldwide. Previous studies focused on the overall population in China. However, variations in temporal...

    Authors: Chenran Wang, Chunping Wang, Mi Liu, Zhe Chen and Shiwei Liu

    Citation: BMC Cardiovascular Disorders 2020 20:243

    Content type: Research article

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  2. Cardiac fibroblasts, regarded as the immunomodulatory hub of the heart, have been thought to play an important role during sepsis-induced cardiomyopathy (SIC). However, the detailed molecular mechanism and tar...

    Authors: Jingjing Ji, Zhifeng Liu, Xinxin Hong, Zheying Liu, Jinghua Gao and Jinghua Liu

    Citation: BMC Cardiovascular Disorders 2020 20:242

    Content type: Research article

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  3. Mean platelet volume (MPV) has been identified as an individual risk factor for stroke and thrombosis. Concurrently, ischaemic stroke caused by nonvalvular atrial fibrillation (AF) has attracted increasing att...

    Authors: Meifang Zheng, Shean Chen, Ye Zhu and Xiang Gu

    Citation: BMC Cardiovascular Disorders 2020 20:241

    Content type: Research article

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  4. This study aimed to investigate the regulatory effect of rno-microRNA-30c-5p (rno-miR-30c-5p) on myocardial ischemia reperfusion (IR) injury in rats and the underlying molecular mechanisms.

    Authors: Jianfeng Chen, Mingming Zhang, Shouyan Zhang, Junlong Wu and Shufeng Xue

    Citation: BMC Cardiovascular Disorders 2020 20:240

    Content type: Research article

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  5. This study evaluated the association of frequency of potato and rice consumption with cardiometabolic risk factors in children and adolescents.

    Authors: Fereshteh Baygi, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Gita Shafiee, Kourosh Nouri, Zeinab Ahadi, Armita Mahdavi-Gorab, Ramin Heshmat and Roya Kelishadi

    Citation: BMC Cardiovascular Disorders 2020 20:239

    Content type: Research article

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  6. Prevalence of coronary heart disease (CHD) risk factors are increasing in developing countries. The present study aimed to assess the prevalence of self-reported CHD and evaluate the role of various risk facto...

    Authors: Ali Ghaemian, Maryam Nabati, Majid Saeedi, Motahareh Kheradmand and Mahmood Moosazadeh

    Citation: BMC Cardiovascular Disorders 2020 20:238

    Content type: Research article

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  7. The current analysis was performed to estimate the percentage and number of Chinese adults with hypertension and the percentage and number of Chinese adults recommended to receive pharmacological antihypertens...

    Authors: Yundi Jiao, Zhaoqing Sun, Yanxia Xie, Jia Zheng, Zhao Li, Xiaofan Guo, Yue Dai, Liqiang Zheng and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2020 20:237

    Content type: Research article

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  8. Atrial fibrillation (AF) is the most common supra ventricular cardiac arrhythmia, which presents with variety of clinical symptoms. Hypertension increases risk of developing Atrial fibrillation by 1.5 fold. To...

    Authors: Smita Bhalia, Pedro Pallangyo, Abuu Dalidali, Saada Salum, Richard Kawajika, Edna Kajuna, Happiness Kusiima, Engerasiya Kifai, Peter Kisenge, Tatizo Waane and Mohamed Janabi

    Citation: BMC Cardiovascular Disorders 2020 20:235

    Content type: Research article

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  9. Cardiovascular disease (CVD) mortality is substantially higher in Russia than in neighbouring Norway. We aimed to compare blood pressure- and lipid-lowering medication use and proportion meeting treatment targ...

    Authors: Sarah Cook, Laila A. Hopstock, Anne Elise Eggen, Katie Bates, Olena Iakunchykova, Anna Kontsevaya, Martin McKee, Henrik Schirmer, Michael Voevoda, Alexander V. Kudryavtsev, Sofia Malyutina and David A. Leon

    Citation: BMC Cardiovascular Disorders 2020 20:234

    Content type: Research article

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  10. May-Thurner syndrome (MTS) or Cockett’s syndrome is a rare clinical syndrome, which refers to the compression of the left common iliac vein (LCIV) by right common iliac artery and vertebral body. Complications...

    Authors: Yan Meng, Hao Qin, Qiang Ma, Junbo Zhang, Bo Zhang, Honggang Pang, Qian Yin and Hongyan Tian

    Citation: BMC Cardiovascular Disorders 2020 20:233

    Content type: Case report

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  11. We performed a systematic review and meta-analysis of the Matrix metalloproteinases (MMP)-9 (C1562T), MMP-9 (R279Q), MMP-9 (P574R) and MMP-9 (R668Q) polymorphisms and risk of Coronary Artery Disease (CAD).

    Authors: Reza Hassanzadeh-Makoui, Bahman Razi, Saeed Aslani, Danyal Imani and Seyedeh Samaneh Tabaee

    Citation: BMC Cardiovascular Disorders 2020 20:232

    Content type: Research article

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  12. Children with congenital heart disease (CHD) have an elevated risk of future cardiovascular disease but the underlying mechanisms are unclear. Abdominal obesity (measured as waist circumference) is a risk fact...

    Authors: Erin Barbour-Tuck, Natasha G. Boyes, Corey R. Tomczak, Dana S. Lahti, Chantelle L. Baril, Charissa Pockett, Shonah Runalls, Ashok Kakadekar, Scott Pharis, Timothy J. Bradley, Kristi D. Wright and Marta C. Erlandson

    Citation: BMC Cardiovascular Disorders 2020 20:231

    Content type: Research article

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  13. Preoperative risk prediction in patients at elevated cardiovascular risk shows limited accuracy. Platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) indicate systemic inflammation. Both...

    Authors: Jan Larmann, Jessica Handke, Anna S. Scholz, Sarah Dehne, Christoph Arens, Hans-Jörg Gillmann, Florian Uhle, Johann Motsch, Markus A. Weigand and Henrike Janssen

    Citation: BMC Cardiovascular Disorders 2020 20:230

    Content type: Research article

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  14. To explore why bicuspid aortic stenosis has certain clinical differences from the tricuspid morphology, we evaluated the metabolomics profile involved in bicuspid aortic valve (BAV) aortic stenosis prior to an...

    Authors: Tian-Yuan Xiong, Chang Liu, Yan-Biao Liao, Wen Zheng, Yi-Jian Li, Xi Li, Yuanweixiang Ou, Zi-Jie Wang, Xi Wang, Chang-Ming Li, Zhen-Gang Zhao, Yuan Feng, Xiao-Jing Liu and Mao Chen

    Citation: BMC Cardiovascular Disorders 2020 20:229

    Content type: Research article

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  15. Inflammation and skeletal muscle wasting often coexist in elderly populations, but few studies have examined their relationship in elderly heart failure (HF) patients. This study examined the relationship betw...

    Authors: Masayuki Koshikawa, Masahide Harada, Shunsuke Noyama, Ken Kiyono, Yuji Motoike, Yoshihiro Nomura, Asuka Nishimura, Hideo Izawa, Eiichi Watanabe and Yukio Ozaki

    Citation: BMC Cardiovascular Disorders 2020 20:228

    Content type: Research article

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  16. As a result of advances in pediatric care and diagnostic testing, there is a growing population of adults with congenital heart disease (ACHD). The purpose of this study was to better define the epidemiology a...

    Authors: Sang-Yun Lee, Gi-Beom Kim, Hye-Won Kwon, Mi-kyoung Song, Eun Jung Bae, Sungkyu Cho, Jae Gun Kwak, Hong-Gook Lim, Woong-Han Kim and Jeong-Ryul Lee

    Citation: BMC Cardiovascular Disorders 2020 20:227

    Content type: Research article

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  17. We aimed to investigate the association of lesion-specific epicardial adipose tissue (EAT) volume and density with the presence of myocardial ischemia.

    Authors: Yu Du, Lin Yang, Yan Liu, Bangguo Yang, Sai Lv, Chenping Hu, Yong Zhu, Hongkai Zhang, Qian Ma, Zhijian Wang, Yuyang Liu, Dongmei Shi, Yingxin Zhao, Lei Xu and Yujie Zhou

    Citation: BMC Cardiovascular Disorders 2020 20:226

    Content type: Research article

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  18. There are limited data regarding the impact of bioresorbable polymer drug eluting stent (BP-DES) compared to durable polymer drug eluting stent (DP-DES) in patients treated with percutaneous coronary intervent...

    Authors: Mario Iannaccone, Umberto Barbero, Michele De Benedictis, Yoichi Imori, Giorgio Quadri, Daniela Trabattoni, Nicola Ryan, Giuseppe Venuti, Andrea Montabone, Wojciech Wojakowski, Andrea Rognoni, Gerard Helft, Radoslaw Parma, Leonardo De Luca, Michele Autelli, Giacomo Boccuzzi…

    Citation: BMC Cardiovascular Disorders 2020 20:225

    Content type: Research article

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  19. Timely restoration of bloodflow acute ST-segment elevation myocardial infarction (STEMI) reduces myocardial damage and improves prognosis. The objective of this study was describe the association of demographi...

    Authors: Lee K. Taylor, Michael A. Nelson, Marianne Gale, Judy Trevena, David B. Brieger, Scott Winch, Michelle A. Cretikos, Leah A. Newman, Hai N. Phung, Steven C. Faddy, Paul M. Kelly and Kerry Chant

    Citation: BMC Cardiovascular Disorders 2020 20:224

    Content type: Research Article

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  20. Although hospital readmission for heart failure (HF) is an issue for both men and women, little is known about differences in readmission rates by sex. Consequently, strategies to optimize readmission reductio...

    Authors: Amy Hoang-Kim, Camilla Parpia, Cassandra Freitas, Peter C. Austin, Heather J. Ross, Harindra C. Wijeysundera, Karen Tu, Susanna Mak, Michael E. Farkouh, Louise Y. Sun, Michael J. Schull, Robin Mason, Douglas S. Lee and Paula A. Rochon

    Citation: BMC Cardiovascular Disorders 2020 20:223

    Content type: Research article

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  21. Uncertainty still remains on the correlation of methylenetetrahydrofolate reductase (MTHFR) variant C677T with risk of carotid atherosclerosis (CAS), and there is a lack of reports on C677T/MTHFR in the Asian pop...

    Authors: Xulei Peng, Yongli Zhou, Xiaoxing Wu, Xiaolin Wang, Huili Bai, Yongqiang Li, Zhichao Wang, Xuan Chen and Yonghong Wang

    Citation: BMC Cardiovascular Disorders 2020 20:222

    Content type: Research article

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  22. Atrial fibrillation (AF), one of the most common comorbidities of heart failure (HF), is associated with worse long-term prognosis in HF patients receiving cardiac resynchronization therapy (CRT). However, the...

    Authors: Minsi Cai, Wei Hua, Nixiao Zhang, Shengwen Yang, Yiran Hu, Min Gu, Hongxia Niu and Shu Zhang

    Citation: BMC Cardiovascular Disorders 2020 20:221

    Content type: Research article

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  23. The lesions of aberrant right subclavian artery, Kommerell’s diverticulum and type A aortic intramural hematoma are rare, and we usually treat them with open surgery. In some cases patients have increased risk...

    Authors: Sizheng Xiong, Daoquan Wang and Jun Li

    Citation: BMC Cardiovascular Disorders 2020 20:220

    Content type: Case report

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  24. Atrioesophageal fistula (AEF) is the most fatal complication associated with catheter ablation for atrial fibrillation and cannot be easily detected when thoracic contrast-enhanced computed tomography (CT) is ...

    Authors: Bing Rong, Xiquan Zhang, Hui Tian, Hongyu Zhang, Ning Zhong and Jingquan Zhong

    Citation: BMC Cardiovascular Disorders 2020 20:219

    Content type: Case report

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  25. Abnormal glucose metabolism has been suggested to be involved in the development of hypertension. This study investigated the effect of the association and potential interaction of glycosylated hemoglobin (HbA...

    Authors: Jian Song, Nana Wei, Yingying Zhao, Yuhong Jiang, Xuesen Wu and Huaiquan Gao

    Citation: BMC Cardiovascular Disorders 2020 20:218

    Content type: Research article

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  26. Prior studies have shown insulin resistance is associated with reduced cardiac autonomic function measured at rest, but few studies have determined whether insulin resistance is associated with reduced cardiac...

    Authors: Anna K. Poon, Eric A. Whitsel, Gerardo Heiss, Elsayed Z. Soliman, Lynne E. Wagenknecht, Takeki Suzuki and Laura Loehr

    Citation: BMC Cardiovascular Disorders 2020 20:217

    Content type: Research article

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  27. Exclusive use of Del Nido cardioplegia administration in all adult patients undergoing cardiac surgery has been studied for operative, postoperative and myocardial protection outcomes.

    Authors: Mohamed Marzouk, Valerie Lafreniere-Bessi, Stephanie Dionne, Serge Simard, Christian Pigeon, François Dagenais, Niv Ad and Frederic Jacques

    Citation: BMC Cardiovascular Disorders 2020 20:215

    Content type: Research article

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  28. Epicardial adipose tissue (EAT) remodeling and adipocytokines are associated with structural remodeling in atrial fibrillation (AF). However, the role of omentin-1, a novel adipocytokine, in structural remodel...

    Authors: Yubin Chen, Fen Liu, Fei Han, Lizhi Lv, Can-e Tang, Zhongshang Xie and Fanyan Luo

    Citation: BMC Cardiovascular Disorders 2020 20:214

    Content type: Research article

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  29. There is a paucity of evidence on the combination of the SYNTAX score II (SSII) and erythrocyte sedimentation rate (ESR) in assessing the long-term prognosis of patients with ST-elevated myocardial infarction ...

    Authors: Chuang Li, Qian Zhang, Qianhui Wang, Jiuchang Zhong, Lefeng Wang, Kuibao Li and Xinchun Yang

    Citation: BMC Cardiovascular Disorders 2020 20:213

    Content type: Research article

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  30. We aimed to investigate the natural course of coronary artery calcium progression in an Asian population with a baseline coronary artery calcium (CAC) score of zero, and to determine subclinical coronary ather...

    Authors: Yi-Wen Shen, Yun-Ju Wu, Yi-Chi Hung, Chia-Chi Hsiao, Shan-Ho Chan, Guang-Yuan Mar, Ming-Ting Wu and Fu-Zong Wu

    Citation: BMC Cardiovascular Disorders 2020 20:212

    Content type: Research article

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  31. Lipid infiltration and inflammatory response run through the occurrence of atherosclerosis. Differentiation into macrophages and foam cell formation are the key steps of AS. Aim of this study was that the diff...

    Authors: Zikai Song, Shijie Lv, Haidi Wu, Ling Qin, Hongyan Cao, Bo Zhang and Shuping Ren

    Citation: BMC Cardiovascular Disorders 2020 20:211

    Content type: Research article

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  32. Right free wall accessory pathways (AP) are difficult to treat with catheter ablation as ablation catheter (AC) instability at the tricuspid annulus often precludes successful procedure.

    Authors: Matevž Jan, Tine Prolič Kalinšek, Jernej Štublar, Matija Jelenc, Andrej Pernat, David Žižek and Nikola Lakič

    Citation: BMC Cardiovascular Disorders 2020 20:210

    Content type: Research article

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  33. Aortic stenosis (AS) is a common cardiac condition whose prevalence increases with age. The symptom burden associated with severe aortic stenosis (AS) can introduce significant lifestyle disruptions and if lef...

    Authors: Rima Styra, Michelle Dimas, Kathy Svitak, Mamta Kapoor, Mark Osten, Maral Ouzounian, Gerald Devins, Amy Deckert and Eric Horlick

    Citation: BMC Cardiovascular Disorders 2020 20:209

    Content type: Research article

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  34. Early reperfusion of the coronary artery has become the first choice for patients with ST-segment elevation myocardial infarction (STEMI). How to deal with patients who miss the time window for early reperfusi...

    Authors: Qixin Guo, Jinyu Huang, Yong Shen, Guoxin Tong, Hong Li and Shasha Meng

    Citation: BMC Cardiovascular Disorders 2020 20:207

    Content type: Research article

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  35. In recent years, the field of cardio-oncology has grown worldwide, bringing benefits to cancer patients in terms of survival and quality of life. This study reports the experience of a pioneer cardio-oncology ...

    Authors: Isabela B. S. da S. Costa, Cristina S. Bittar, Silvia M. R. Fonseca, Carolina M. P. D. e Silva, Marilia H. H. dos Santos Rehder, Stéphanie I. Rizk, Cecilia B. B. V. Cruz, Clara S. Figueiredo, Fernanda T. de A. Andrade, Ludmila de A. Barberino, Fernanda A. de S. Costa, Letticya P. Machado, Thalita B. González, Marcel P. C. Almeida, Julia T. Fukushima, Roberto Kalil Filho…

    Citation: BMC Cardiovascular Disorders 2020 20:206

    Content type: Research article

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  36. Non-ischemic cardiomyopathy (NICM) has been associated with a better left ventricle reverse remodeling response and improved clinical outcomes after cardiac resynchronization therapy (CRT). The aims of our stu...

    Authors: Shengwen Yang, Zhimin Liu, Yiran Hu, Ran Jing, Min Gu, Hongxia Niu, Ligang Ding, Anlu Xing, Shu Zhang and Wei Hua

    Citation: BMC Cardiovascular Disorders 2020 20:205

    Content type: Research article

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  37. Heart failure (HF) is relatively common cardiovascular disease with high mortality and morbidity. Although it is associated with many cardiovascular risk factors, the association between nonalcoholic fatty liv...

    Authors: Jae-Hyung Roh, Jae-Hyeong Park, Hanbyul Lee, Yong-Hoon Yoon, Minsu Kim, Yong-Giun Kim, Gyung-Min Park, Jae-Hwan Lee and In-Whan Seong

    Citation: BMC Cardiovascular Disorders 2020 20:204

    Content type: Research article

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  38. The effectiveness of a 2015–17 community intervention to reduce cardiovascular disease (CVD) and type 2 diabetes (T2DM) risk factors is assessed in a Sri Lanka adult population, using a before-and-after study ...

    Authors: L. Gamlath, S. Nandasena, P. de Silva, S. Morrell, C. Linhart, S. Lin, A. Sharpe, S. Nathan and R. Taylor

    Citation: BMC Cardiovascular Disorders 2020 20:203

    Content type: Research Article

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  39. Heart failure (HF) represents an accumulated burden of systemic vascular damage and is the fastest growing form of cardiovascular disease (CVD). Due to increasing HF-attributable mortality rates, we sought to ...

    Authors: Alexander C. Razavi, Kaitlin S. Potts, Tanika N. Kelly, Jiang He, Camilo Fernandez, Marie Krousel-Wood, Amanda H. Anderson, Joshua Bundy, Seamus P. Whelton, Roger S. Blumenthal, Donald Lloyd-Jones and Lydia A. Bazzano

    Citation: BMC Cardiovascular Disorders 2020 20:202

    Content type: Research article

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  40. Statin remains a mainstay in the prevention and treatment of cardiovascular diseases. Statin utilization has evolved over time in many countries, but data on this topic from China are quite limited. This study...

    Authors: Yujuan Liu, Xiaoqun Lv, Ning Xie, Zhonghong Fang, Weifang Ren, Yuan Gong, Yan Jin and Jun Zhang

    Citation: BMC Cardiovascular Disorders 2020 20:201

    Content type: Research article

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  41. Exercise intolerance is a common finding in heart failure that generates a vicious cycle in which the individual starts to limit his activities even more due to progressive fatigue. Regular physical exercise c...

    Authors: Daniela Meirelles do Nascimento, Karina Costa Machado, Patrícia Martins Bock, Marco Aurélio Lumertz Saffi, Livia Adams Goldraich, Anderson Donelli Silveira, Nadine Clausell and Beatriz D. Schaan

    Citation: BMC Cardiovascular Disorders 2020 20:200

    Content type: Study protocol

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  42. The Global Registry of Acute Coronary Events (GRACE) score is recommended for stratifying chest pain. However, there are six formulas used to calculate the GRACE score for different outcomes of acute coronary ...

    Authors: Wen Zheng, Guangmei Wang, Jingjing Ma, Shuo Wu, He Zhang, Jiaqi Zheng, Feng Xu, Jiali Wang and Yuguo Chen

    Citation: BMC Cardiovascular Disorders 2020 20:199

    Content type: Research article

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  43. Heat shock protein 27 (HSP27) has been proposed as a vital protective factor in atherosclerosis. The objective of the present study was to evaluate the association between circulating HSP27 and carotid intima–...

    Authors: Xinru Wang, Jie Shi, Bin Lu, Weiwei Zhang, Yehong Yang, Jie Wen, Renming Hu, Zhen Yang and Xuanchun Wang

    Citation: BMC Cardiovascular Disorders 2020 20:198

    Content type: Research article

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  44. Previous studies have found that impaired global myocardial systolic strain is associated with cardiovascular events in T2DM patients. However, the effect of hypertension (HT) on left atrial (LA), right ventri...

    Authors: Guozhu Shao, Yukun Cao, Yue Cui, Xiaoyu Han, Jia Liu, Yumin Li, Na Li, Tong Liu, Jie Yu and Heshui Shi

    Citation: BMC Cardiovascular Disorders 2020 20:196

    Content type: Research article

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  45. Advanced glycation end products (AGEs) are associated with aging, diabetes mellitus (DM), and other chronic diseases. Recently, the accumulation of AGEs can be evaluated by skin autofluorescence (SAF). However...

    Authors: Mitsuhiro Kunimoto, Kazunori Shimada, Miho Yokoyama, Tomomi Matsubara, Tatsuro Aikawa, Shohei Ouchi, Megumi Shimizu, Kosuke Fukao, Tetsuro Miyazaki, Tomoyasu Kadoguchi, Kei Fujiwara, Abidan Abulimiti, Akio Honzawa, Miki Yamada, Akie Shimada, Taira Yamamoto…

    Citation: BMC Cardiovascular Disorders 2020 20:195

    Content type: Research article

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