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  1. PCSK9 gene expression is associated with biological processes such as lipid metabolism, glucose metabolism, and inflammation. In the present study, our primary objective was to assess the association between t...

    Authors: Meng-Meng Wang, Chen-Fei Lu, Shi-qi Yan, Bao-Zhu Wang, Gulinazi Yesitayi, Yong-Liang Tian, Xiang-Ma and Yi-Tong Ma
    Citation: BMC Cardiovascular Disorders 2022 22:284
  2. The formation of advanced glycation end-products (AGEs) is a crucial risk factor for the pathogenesis of cardiovascular diseases in diabetes. We investigated whether N-epsilon-carboxymethyllysine (CML), a majo...

    Authors: Le-Ying Li, Shuai Chen, Fei-Fei Li, Zhi-Ming Wu, Ying Shen, Feng-Hua Ding, Xiao-Qun Wang, Wei-Feng Shen, Qiu-Jing Chen, Yang Dai and Lin Lu
    Citation: BMC Cardiovascular Disorders 2022 22:282
  3. Coronary heart disease (CHD) is one of the most common causes of morbidity and mortality in type 2 diabetes mellitus (T2DM). Oxidative stress is one of the important contributors to the pathogenesis of CHD. Se...

    Authors: Xue Tian, Yu Gao, Min Zhong, Mowei Kong, Lihua Zhao, Zengbin Feng, Qitian Sun, Jianqiu He and Xiaoyan Liu
    Citation: BMC Cardiovascular Disorders 2022 22:281
  4. Neuropsychiatric side effects of cardiac drugs such as nervousness, mood swings and agitation may be misinterpreted as symptoms of anxiety. Anxiety in cardiac patients is highly prevalent and associated with p...

    Authors: Camilla Rotvig, Anne Vinggaard Christensen, Knud Juel, Jesper Hastrup Svendsen, Martin Balslev Jørgensen, Trine Bernholdt Rasmussen, Britt Borregaard, Lars Thrysoee, Charlotte Brun Thorup, Rikke Elmose Mols and Selina Kikkenborg Berg
    Citation: BMC Cardiovascular Disorders 2022 22:280
  5. Left ventricular diastolic dysfunction (LVDD) is a recognized complication of diabetes mellitus that precedes and is a risk factor for heart failure. We aimed to determine the prevalence of LVDD and its associ...

    Authors: Boniface Amanee Elias Lumori, Edwin Nuwagira, Fardous Charles Abeya, Abdirahman Ali Araye, Godfrey Masette, Charles K. Mondo, Samson Okello, Conrad Muzoora and Anthony Muyingo
    Citation: BMC Cardiovascular Disorders 2022 22:279
  6. Familial hypertrophic cardiomyopathy (FHCM) is an autosomal dominant inherited disease caused by mutations in genes encoding cardiac sarcomere proteins. MicroRNAs (miRNAs) play an important role in the pathoge...

    Authors: Li-rong Lin, Xue-qun Hu, Li-hong Lu, Jia-zhen Dai, Ning-ning Lin, Re-hua Wang, Zhang-xin Xie and Xue-mei Chen
    Citation: BMC Cardiovascular Disorders 2022 22:278
  7. Acute thrombosis of an abdominal aortic aneurysm with acute limb ischaemia is an unusual complication and is associated with high mortality. Dislocation of the intrasaccular mural thrombus could be one of the ...

    Authors: Ying-Sheng Li and Ying-Ching Li
    Citation: BMC Cardiovascular Disorders 2022 22:277
  8. Hyponatremia is a common electrolyte abnormality that has been associated with poor outcomes in several conditions including acute myocardial infarction (AMI). However, those studies were performed in the era ...

    Authors: Andres Cordova Sanchez, Kunal Bhuta, Gary Shmorgon, Nicholas Angeloni, Ryan Murphy and Debanik Chaudhuri
    Citation: BMC Cardiovascular Disorders 2022 22:276
  9. Adherence to self-care recommendations in heart failure (HF) patients is essential to improve the patients’ quality of life, prevent hospital admission, and reduce mortality and morbidity. Nevertheless, poor a...

    Authors: Aemiro Baymot, Debela Gela and Tadesse Bedada
    Citation: BMC Cardiovascular Disorders 2022 22:275
  10. Left bundle branch pacing (LBBP) has become a hot topic in the field of physiological pacing. However, only a few studies have described the characteristics of the intrinsic intracardiac electrogram (EGM) whil...

    Authors: Xiaojie Cai, Longfu Jiang, Shanshan Zhuo and Hao Wu
    Citation: BMC Cardiovascular Disorders 2022 22:274
  11. Dyslipidemia is one of independent risk factors for coronary atherosclerotic heart disease (CAHD). We determined whether the LDL/HDL ratio is better than LDL-C or HDL-C alone in predicting the severity of CAHD.

    Authors: Ting Sun, Mengyun Chen, Huanhuan Shen, PingYin, Li Fan, Xin Chen, Jun Wu, Zuojun Xu and Junfeng Zhang
    Citation: BMC Cardiovascular Disorders 2022 22:273
  12. The aim of this study is to assess the burden of AF-related hospitalizations inclusive of inflation-adjusted cost-of-care and length-of-stay (LOS) among cancer patients and the impact of direct current cardiov...

    Authors: Avirup Guha, Anubhav Jain, Ankita Aggarwal, Amit K. Dey, Sourbha Dani, Sarju Ganatra, Francis E. Marchlinski, Daniel Addison and Michael G. Fradley
    Citation: BMC Cardiovascular Disorders 2022 22:272
  13. Various randomized multicenter studies have shown that percutaneous left atrial appendage closure (LAAC) is not inferior in stroke prevention compared to vitamin K antagonists (VKA) and can be performed safely...

    Authors: Lucie Kretzler, Christoph Mues, Carsten Wunderlich, Anke Langbein, S. G. Spitzer, Ulrich Gerk, Sebastian Schellong, Thomas Ketteler, Hans Neuser, Marcus Schwefer, Ruth Strasser, Karim Ibrahim, Steffen Schoen and Marian Christoph
    Citation: BMC Cardiovascular Disorders 2022 22:271
  14. Cardiac rehabilitation for heart failure continues to be greatly underused worldwide despite being a Class I recommendation in international clinical guidelines and uptake is low in women and patients with men...

    Authors: Paulina Daw, Alexander Harrison, Patrick J. Doherty, Jet J. C. S. Veldhuijzen van Zanten, Hasnain M. Dalal, Rod S. Taylor, Samantha B. van Beurden, Sinéad T. J. McDonagh and Colin J. Greaves
    Citation: BMC Cardiovascular Disorders 2022 22:270
  15. The causal association between educational attainment (EA) and stroke remains unclear. Hence, a novel multivariable Mendelian randomization (MVMR) approach was applied to solve this issue.

    Authors: Weihao Zhang, Yuanjin Li, Yuming Li, Kai Zheng, Shenghui Zou, Xing Jia and Hua Yang
    Citation: BMC Cardiovascular Disorders 2022 22:269
  16. The rest-only single photon emission computerized tomography (SPECT) myocardial perfusion imaging (MPI) had low sensitivity in diagnosing obstructive coronary artery disease (CAD). Improving the efficacy of re...

    Authors: Bao Liu, Wenji Yu, Jianfeng Wang, Xiaoliang Shao, Feifei Zhang, Mingge Zhou, Yunmei Shi, Bing Wang, Yiduo Xu and Yuetao Wang
    Citation: BMC Cardiovascular Disorders 2022 22:268
  17. A better understanding of how cardiorespiratory fitness (CRF) and adiposity interact to associate with arterial blood pressure over time remains inconclusive. Thus, the aim of the present study was to examine ...

    Authors: Caroline Brand, Ana Paula Sehn, Camila Felin Fochesatto, João Francisco de Castro Silveira, Jorge Mota, David Martinez Gomez, Anelise Reis Gaya, Cézane Priscila Reuter and Jane Dagmar Pollo Renner
    Citation: BMC Cardiovascular Disorders 2022 22:267
  18. Rheumatic heart disease (RHD) is the most commonly acquired heart disease in children and young people in low and middle-income settings. Fragile health systems and scarcity of data persist to limit the unders...

    Authors: Panduleni Penipawa Shimanda, Stefan Söderberg, Scholastika Ndatinda Iipinge, Ebba Mwalundouta Neliwa, Fenny Fiindje Shidhika and Fredrik Norström
    Citation: BMC Cardiovascular Disorders 2022 22:266
  19. Left ventricular diastolic dysfunction (LVDD) is common in hypertension and is a predictor of increased cardiovascular risk, however the effect of LVDD, detected by new guideline, on major adverse cardiac even...

    Authors: Dan Zhou, Mengqi Yan, Qi Cheng, Xiaoxuan Feng, Songtao Tang and Yingqing Feng
    Citation: BMC Cardiovascular Disorders 2022 22:265
  20. Our study aimed to investigate the association between epicardial adipose tissue (EAT) and atrial fibrillation (AF) recurrence risk after catheter ablation.

    Authors: Jun Chen, Ziwei Mei, Yang Yang, Chuxing Dai, Yimin Wang, Rui Zeng and Qiang Liu
    Citation: BMC Cardiovascular Disorders 2022 22:264
  21. Metabolic syndrome (MetS) increases the risk of new diabetes and cardiovascular disease. Night shift work (NSW) may influence metabolic disturbance and lead to MetS. This study aims to investigate the associat...

    Authors: Chaohui Dong, Honglian Zeng, Bo Yang, Yi Zhang and Zhitao Li
    Citation: BMC Cardiovascular Disorders 2022 22:263
  22. Previous studies have observed inconsistent associations between coronavirus disease 2019 (COVID-19) and heart failure (HF), but these studies were prone to bias based on reverse causality and residual confoun...

    Authors: Huachen Wang, Zheng Guo, Yulu Zheng and Bing Chen
    Citation: BMC Cardiovascular Disorders 2022 22:262
  23. More and more evidence indicates sodium-glucose co-transporter 2 inhibitors (SGLT2is) may display clinical benefits for heart failure with preserved ejection fraction (HFpEF). However, the mechanisms of the ac...

    Authors: Bo Liang, Yi Liang and Ning Gu
    Citation: BMC Cardiovascular Disorders 2022 22:261
  24. The lack of dystrophin in cardiomyocytes in Duchenne muscular dystrophy (DMD) is associated with progressive decline in cardiac function eventually leading to death by 20–40 years of age. The aim of this prosp...

    Authors: Abhinandan Batra, Alison M. Barnard, Donovan J. Lott, Rebecca J. Willcocks, Sean C. Forbes, Saptarshi Chakraborty, Michael J. Daniels, Jannik Arbogast, William Triplett, Erik K. Henricson, Jonathan G. Dayan, Carsten Schmalfuss, Lee Sweeney, Barry J. Byrne, Craig M. McDonald, Krista Vandenborne…
    Citation: BMC Cardiovascular Disorders 2022 22:260
  25. The effect of bone marrow-derived mononuclear cells (BM-MNCs) after acute myocardial infarction (AMI) on myocardial function indices such as left ventricular ejection fraction has been widely studied. However,...

    Authors: Armin Attar, Alireza Hosseinpour, Hamidreza Hosseinpour and Asma Kazemi
    Citation: BMC Cardiovascular Disorders 2022 22:259
  26. Although Blood urea nitrogen (BUN) and serum creatinine concentration (Cr) has been widely measured in daily clinical practice, BUN-to-Cr ratio (BCR) for prognosis among patients admitted with cardiogenic shoc...

    Authors: Di Sun, Changmin Wei and Zhen Li
    Citation: BMC Cardiovascular Disorders 2022 22:258
  27. Immune abnormalities and inflammatory responses play critical roles in progression of hypertension. Basic studies have confirmed that Th17 cell and related cytokines are important in promoting hypertension-med...

    Authors: Zhuoqun Wang, Jiannan Wang, Pengfei Yang, Xiwen Song and Yongle Li
    Citation: BMC Cardiovascular Disorders 2022 22:257
  28. Spontaneous coronary artery dissection (SCAD) is now recognized as an important cause of acute coronary syndrome (ACS), which is thought to be more prevalent in women. However, the male patients, on the other ...

    Authors: Yongjun Li, Mingming Yang, Xi Chen, Xiaoguo Zhang, Rui Zhang, Pengfei Zuo, Lei Jiang and Genshan Ma
    Citation: BMC Cardiovascular Disorders 2022 22:256
  29. Thoracic aortic aneurysm (TAA), is a pathological dilatation of the aortic segment with the tendency to expand, dissect or rupture, and risk of mortality. The progression rate is mainly slow. As the risk of ru...

    Authors: Mohammadbagher Sharifkazemi, Mohammadhassan Nemati, Seyed Mohammad Owji and Leila Ahmadi
    Citation: BMC Cardiovascular Disorders 2022 22:254
  30. Pressure–volume (PV) loops provide comprehensive information of cardiac function, but commonly implies an invasive procedure under general anesthesia. A novel technique has made it possible to non-invasively e...

    Authors: Pia Sjöberg, Petru Liuba, Håkan Arheden, Einar Heiberg and Marcus Carlsson
    Citation: BMC Cardiovascular Disorders 2022 22:253
  31. Commotio cordis is an event in which a blunt, non-penetrating blow to the chest occurs, triggering a life-threatening arrhythmia and often sudden death. This phenomenon is often seen in young, male athletes an...

    Authors: Neha Patel, Clarissa Pena, Zeid Nesheiwat, Fnu Zafrullah and Ehab Eltahawy
    Citation: BMC Cardiovascular Disorders 2022 22:252
  32. Endothelial dysfunction appears early in the development of cardiovascular disease and is associated with type 2 diabetes. We, therefore, tested the hypothesis that endothelial dysfunction is already present i...

    Authors: Yingwei Wang, Guangxia Li, Jing Qi, Ting Gong, Xiudong Li, Fanghe Liu, Xuejing Bi, Yang Zhao, Meihua Liang, Xiaodong Zheng and Yuandong Qiao
    Citation: BMC Cardiovascular Disorders 2022 22:251
  33. Few studies examined the relationship between triglyceride/glucose index (TyG index) and atherosclerosis in Japanese adults. Therefore, this study evaluated their relationship, as measured based on the brachia...

    Authors: Xingping Yang, Zhao Gao, Xuming Huang, Mingxing Zhang and Zhuoming Chen
    Citation: BMC Cardiovascular Disorders 2022 22:250
  34. Blood lipids are strong risk factors for the progression of atherosclerotic plaques. However, data on gender-specific associations are limited.

    Authors: Sumaya Al Helali, Muhammad Abid Hanif, Ahmad Al Majed, Nura Alshugair, Abdullah Belfageih, Hamad Al Qahtani and Sameer Al Dulikan
    Citation: BMC Cardiovascular Disorders 2022 22:249
  35. Cellular and animal studies have shown that endoplasmic reticulum protein B (Nogo-B) is associated with hypertension, but that association has not been fully studied in humans. Therefore, the expression levels...

    Authors: Shunuo Li, Jianmeng Zheng, Xiaoxia Dong, Shasha Bi, Liqin Duan, Wei Zheng and Peishi Yan
    Citation: BMC Cardiovascular Disorders 2022 22:248
  36. The relationship between ambulatory arterial stiffness index (AASI) and left ventricular diastolic dysfunction (LVDD) in patients with heart failure with preserved ejection fraction (HFpEF) is unknown. We aime...

    Authors: Hanwen Zhang, Weiwei Hu, Yu Wang, Jie Liu, Linna You, Qian Dong, Guanglei Chang, Xiaocheng Cheng, Zhiqiang Liu and Dongying Zhang
    Citation: BMC Cardiovascular Disorders 2022 22:246
  37. Knowing of perception of the illness, and cardiovascular risk factors in patients with myocardial infarction is crucial in engaging in effective secondary prevention. This study aimed to examine illness percep...

    Authors: Aysan Thagizadeh, Akram Ghahramanian, Vahid Zamanzadeh, Naser Aslanabadi, Tonia C. Onyeka and Nargess Ramazanzadeh
    Citation: BMC Cardiovascular Disorders 2022 22:245
  38. The prevalence of cardiovascular disease (CVD) is rapidly increasing in the world. The present study aimed to assess the prevalence and Predictors factors of CVD based on the data of Kherameh cohort study.

    Authors: Najibullah Baeradeh, Masoumeh Ghoddusi Johari, Leila Moftakhar, Ramin Rezaeianzadeh, Seyed Vahid Hosseini and Abbas Rezaianzadeh
    Citation: BMC Cardiovascular Disorders 2022 22:244
  39. Authors: Hamid Sharif Nia, Ozkan Gorgulu, Navaz Naghavi, Erika Sivarajan Froelicher, Fatemeh Khoshnavay Fomani, Amir Hossein Goudarzian, Saeed Pahlevan Sharif, Roghiyeh Pourkia and Ali Akbar Haghdoost
    Citation: BMC Cardiovascular Disorders 2022 22:243

    The original article was published in BMC Cardiovascular Disorders 2021 21:563

  40. The COVID-19 outbreak represents a significant challenge to international health. Several studies have reported a substantial decrease in the number of patients attending emergency departments with acute coron...

    Authors: Mingliang Zuo, Shoubo Xiang, Sanjib Bhattacharyya, Qiuyi Chen, Jie Zeng, Chunmei Li, Yan Deng, Chungwah Siu and Lixue Yin
    Citation: BMC Cardiovascular Disorders 2022 22:242
  41. There are many studies on high-sensitivity C-reactive protein (hs-CRP) association with cardiovascular disease (CVD); however, just a few studies investigated whether the low-density lipoprotein cholesterol (L...

    Authors: Amirhossein Nafari, Noushin Mohammadifard, Fahimeh Haghighatdoost, Shima Nasirian, Jamshid Najafian, Masoumeh Sadeghi, Hamidreza Roohafza and Nizal Sarrafzadegan
    Citation: BMC Cardiovascular Disorders 2022 22:241
  42. Restrictive cardiomyopathy (RCM) presents a high risk for sudden cardiac death in pediatric patients. Constrictive pericarditis (CP) exhibits a similar clinical presentation to RCM and requires differential di...

    Authors: Min Zheng, Hong Huang, Xu Zhu, Harvey Ho, Liling Li and Xiaojuan Ji
    Citation: BMC Cardiovascular Disorders 2022 22:240
  43. Spontaneous isolated superior mesenteric artery (SMA) dissection (SISMAD) is a rare disease with a potentially fatal pathology. Due to the lack of specificity of clinical characteristics and laboratory tests, ...

    Authors: Yuanli Lei, Jinying Liu, Yi Lin, Huiping Li, Wenxing Song, Zhangping Li, Weijia Huang and Shouquan Chen
    Citation: BMC Cardiovascular Disorders 2022 22:239
  44. The prevalence and burden of coronary heart disease (CHD) has increased substantially in India, accompanied with increasing need for percutaneous coronary interventions (PCI). Although a large government-funde...

    Authors: Shuqi Zhang, Mithlesh Chourase, Nupur Sharma, Sujata Saunik, Mona Duggal, Goodarz Danaei and Bhanu Duggal
    Citation: BMC Cardiovascular Disorders 2022 22:238
  45. Non-communicable diseases like systemic arterial hypertension (SAH) and dyslipidemia are poorly studied in terms of patient journey aspects. This semi-systematic review provides evidence synthesis for the mana...

    Authors: Jose Rocha Faria-Neto, Carlos Yarleque, Luiz Fernando Vieira, Eliane Naomi Sakane and Raul D. Santos
    Citation: BMC Cardiovascular Disorders 2022 22:237
  46. We aimed to investigate the effect of the triglyceride glucose (TyG) index on the association between diabetes and cardiovascular disease (CVD).

    Authors: Zixiang Ye, Enmin Xie, Siqi Jiao, Yanxiang Gao, Peizhao Li, Yimin Tu, Ziyu Guo, Qing Li, Yaxin Wu, Xiaozhai Yu, Yike Li, Changan Yu, Jingyi Ren and Jingang Zheng
    Citation: BMC Cardiovascular Disorders 2022 22:236
  47. To elucidate the value of texture analysis (TA) in detecting and differentiating myocardial tissue alterations on T2-weighted CMR (cardiovascular magnetic resonance imaging) in patients with cardiac amyloidosi...

    Authors: Shan Huang, Ke Shi, Yi Zhang, Wei-Feng Yan, Ying-Kun Guo, Yuan Li and Zhi-Gang Yang
    Citation: BMC Cardiovascular Disorders 2022 22:235
  48. Heart failure (HF) is a global illness and is a leading cause of hospitalizations. Recurrent HF hospitalization (HFH) is associated with increased risk of cardiovascular (CV) and all-cause mortality, thereby b...

    Authors: Raquel Lahoz, Ailís Fagan, Martin McSharry, Clare Proudfoot, Stefano Corda and Rachel Studer
    Citation: BMC Cardiovascular Disorders 2022 22:234

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