Articles

Clinical characteristics and therapeutic strategy of frequent accelerated idioventricular rhythm

Accelerated idioventricular rhythm (AIVR) is often transient, considered benign and requires no treatment. This observational study aims to investigate the clinical manifestations, treatment, and prognosis of ...

Authors: Lan Wang, Hailei Liu, Chao Zhu, Kai Gu, Gang Yang, Hongwu Chen, Weizhu Ju, Mingfang Li, Fengxiang Zhang, Bing Yang, Dao Wu Wang and Minglong Chen

Relationship between serum lipid levels and ischemic stroke in patients with atrial fibrillation: a nested case–control study based on the China Atrial Fibrillation Registry

Atrial fibrillation (AF) is an important risk factor for acute ischemic stroke.

Authors: Fei Li, Xin Du, Liu He, Chao Jiang, Shijun Xia, Changsheng Ma and Jianzeng Dong

Clinical prediction scores and early anticoagulation therapy for new-onset atrial fibrillation in critical illness: a post-hoc analysis

This study sought to describe the epidemiology of anticoagulation therapy for critically ill patients with new-onset atrial fibrillation (NOAF) according to CHA2DS2-VASc and HAS-BLED scores and to assess the e...

Authors: Masaaki Sakuraya, Takuo Yoshida, Yusuke Sasabuchi, Shodai Yoshihiro and Shigehiko Uchino

Accuracy of neutrophil to lymphocyte and monocyte to lymphocyte ratios as new inflammatory markers in acute coronary syndrome

Inflammation plays a key role in the development of atherosclerosis and in the pathogenesis of acute coronary syndrome (ACS). Leukocytes and leukocytes ratios were recognized as inflammatory markers in predict...

Authors: Ahmed Mohammed Shumilah, Arwa Mohammed Othman and Anwar Kasim Al-Madhagi

Is obstructive sleep apnoea associated with hypoxaemia and prolonged ICU stay after type A aortic dissection repair? A retrospective study in Chinese population

Although obstructive sleep apnoea (OSA) is prevalent among patients with aortic dissection, its prognostic impact is not yet determined in patients undergoing major vascular surgery. We aimed to investigate th...

Authors: Xin Xi, Yu Chen, Wei-Guo Ma, Jiang Xie, Yong-Min Liu, Jun-Ming Zhu, Ming Gong, Guang-Fa Zhu and Li-Zhong Sun

Individual and combined association analysis of famine exposure and serum uric acid with hypertension in the mid-aged and older adult: a population-based cross-sectional study

Malnutrition in early life may affect health in later life. The associations between malnutrition and serum uric acid (SUA) and hypertension were inconsistent. The present study aimed to investigate the indivi...

Authors: Lin Zhang, Liu Yang, Congzhi Wang, Ting Yuan, Dongmei Zhang, Huanhuan Wei, Jing Li, Yunxiao Lei, Lu Sun, Xiaoping Li, Ying Hua, Hengying Che and Yuanzhen Li

Predicting the 10-year risk of cardiovascular diseases and its relation to healthy diet indicator in Iranian military personnel

Epidemiological studies indicate increased prevalence of cardiovascular disease (CVD) among military personnel. Accordingly, identification of at-risk individuals and lifestyle modification such as improving d...

Authors: Karim Parastouei, Mojtaba Sepandi and Eslam Eskandari

Perioperative risk factors for new-onset postoperative atrial fibrillation after coronary artery bypass grafting: a systematic review

Postoperative atrial fibrillation (POAF) is the most common cardiac dysrhythmia to occur after coronary artery bypass grafting (CABG). However, the risk factors for new-onset POAF after CABG during the periope...

Authors: Eun Ji Seo, Joonhwa Hong, Hyeon-Ju Lee and Youn-Jung Son

Prediction of cardiovascular risk in patients with chronic obstructive pulmonary disease: a study of the National Health and Nutrition Examination Survey database

Cardiovascular disease (CVD) is a common comorbidity associated with chronic obstructive pulmonary disease (COPD), but few studies have been conducted to identify CVD risk in COPD patients. This study was to d...

Authors: Yun Shi, Jing Zhang and Yingshuo Huang

Exploring the diagnostic effectiveness for myocardial ischaemia based on CCTA myocardial texture features

To explore the characteristics of myocardial textures on coronary computed tomography angiography (CCTA) images in patients with coronary atherosclerotic heart disease, a classification model was established, ...

Authors: Hengyu Zhao, Lijie Yuan, Zhishang Chen, Yuting Liao and Jiangzhou Lin

Evaluation of Tp-e interval, Tp-e/QT ratio and index of cardiac-electrophysiological balance in patients with tinnitus

Tinnitus is a common auditory symptom. Dysfunction in the autonomic nervous system (ANS) is an essential part of the etiopathogenesis of tinnitus. ANS regulates heart rate and heart rhythm and can lead to vent...

Authors: Hakan Kaya, Arif Suner, Mehtap Koparal, S. Cem Yucetas and Safiye Kafadar

Clinical characteristics and prognostic implications of diabetes and myocardial injury in patients admitted to the emergency room

This study aimed to investigate the clinical features and prognosis of diabetes and myocardial injury in patients admitted to the emergency department.

Authors: Gil Bonet, Anna Carrasquer, Óscar M. Peiró, Raul Sanchez-Gimenez, Nisha Lal-Trehan, Victor del-Moral-Ronda, Isabel Fort-Gallifa and Alfredo Bardají

Aortic root aortopathy in bicuspid aortic valve associated with high genetic risk

The bicuspid aortic valve (BAV) is prone to ascending aortic dilatation (AAD) involving both the tubular segment and the aortic root. The genetic factor was proposed as one of the most important mechanisms for...

Authors: Mingjia Ma, Zongzhe Li, Mohamed Abdulkadir Mohamed, Ligang Liu and Xiang Wei

Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison

Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain.

Authors: Ali Sheikhy, Aida Fallahzadeh, Saeed Sadeghian, Khalil Forouzannia, Jamshid Bagheri, Abbas Salehi-Omran, Masih Tajdini, Arash Jalali, Mina Pashang and Kaveh Hosseini

Health status measured by Kansas City Cardiomyopathy Questionnaire-12 in primary prevention implantable cardioverter defibrillator patients with heart failure

Self-reported health status as measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ) in patients with primary prevention implantable cardioverter defibrillators (ICDs) has mainly been reported from r...

Authors: Gustav Mattsson, Marita Wallhagen and Peter Magnusson

Cardiology providers’ recommendations for treatments and use of patient decision aids for multivessel coronary artery disease

Rates of recommending percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) vary across clinicians. Whether clinicians agree on preferred treatment options for multivessel coronar...

Authors: Elizabeth L. Nichols, Glyn Elwyn, Anthony DiScipio, Mandeep S. Sidhu, A. James O’Malley, Daniel D. Matlock, Shama Alam, Cathy S. Ross, Megan Coylewright, David J. Malenka and Jeremiah R. Brown

Outcomes of women with congenital heart disease admitted to acute-care hospitals for delivery in Japan: a retrospective cohort study using nationwide Japanese diagnosis procedure combination database

The number of women with congenital heart disease (CHD) who are of childbearing age is increasing due to advancements in medical management. Nonetheless, data on the outcomes of delivery in women with CHD rema...

Authors: Manabu Nitta, Sayuri Shimizu, Makoto Kaneko, Kiyohide Fushimi and Shinichiro Ueda

Case report: Diagnosis and emergency surgery on a young patient with extensive aortic dissection without any risk factors

Type A aortic dissection is a very dangerous, fatal, and emergency condition for surgery. Acute aortic dissection is a rare condition, such that many patients will not survive without reconstructive surgery.

Authors: Masoud Shafiee, Mohsen Shafiee, Noorollah Tahery, Omid Azadbakht, Zeinab Nassari and Reza Baghbani

Implementation of a zero fluoroscopic workflow using a simplified intracardiac echocardiography guided method for catheter ablation of atrial fibrillation, including repeat procedures

Pulmonary vein isolation (PVI) is the cornerstone of the interventional treatment of atrial fibrillation (AF). Traditionally, during these procedures the catheters are guided by fluoroscopy, which poses a risk...

Authors: Tamas Tahin, Adam Riba, Barnabas Nemeth, Ferenc Arvai, Geza Lupkovics, Gabor Szeplaki and Laszlo Geller

Correction to: Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7

Authors: Elisabeth Pedersen, Beate Hennie Garcia, Kjell H. Halvorsen, Anne Elise Eggen, Henrik Schirmer and Marit Waaseth

Giant right atrium, what does it hide? Case presentation

Malformation of the right atrium is a rare cardiac abnormality and is usually reported as isolated malformation in the literature.

Authors: María Martín Talavera, Israel Valverde Pérez and Begoña Manso García

Association of thrombocytopenia and infection in patients with ST-elevation myocardial infarction undergoing percutaneous coronary intervention

The impact of thrombocytopenia on infection in patients with ST-elevation myocardial infarction (STEMI) remains poorly understood.

Authors: Litao Wang, Weijiang Su, Jinhua Xue, Xiao Gong, Yining Dai, Jiyan Chen, Ling Xue, Pengcheng He, Yuanhui Liu and Ning Tan

Abnormalities in lysine degradation are involved in early cardiomyocyte hypertrophy development in pressure-overloaded rats

Cardiomyocyte metabolism changes before cardiac remodeling, but its role in early cardiac hypertrophy detection remains unclear. This study investigated early changes in plasma metabolomics in a pressure-overl...

Authors: Jialing Liu, Junhao Hu, Lanlan Tan, Qi Zhou and Xiaojing Wu

Association of stent diameter and target vessel revascularization in patients undergoing percutaneous coronary intervention: a secondary retrospective analysis based on a Chinese cohort study

In the treatment of coronary heart disease, target vessel revascularization (TVR) has attracted increasing attention as an efficient means of percutaneous coronary intervention (PCI). The purpose of this study...

Authors: Tiancheng Xu, Beili Feng, Zaixing Zheng, Licheng Li, Weifang Zeng, Dongjuan Wang, Lin Zhang and Hengdong Li

Correction to: Myocardial bridging of the left anterior descending coronary artery as a risk factor for atrial fibrillation in patients with hypertrophic obstructive cardiomyopathy: a matched case–control study

An amendment to this paper has been published and can be accessed via the original article.

Authors: Changrong Nie, Changsheng Zhu, Qiulan Yang, Minghu Xiao, Yanhai Meng and Shuiyun Wang

Plasma carbohydrate antigen-125 for prediction of atrial fibrillation recurrence after radiofrequency catheter ablation

Elevated plasma carbohydrate antigen-125 (CA-125) levels are strongly associated with new-onset atrial fibrillation (AF) and heart failure, but the relationship between plasma CA-125 level and AF recurrence fo...

Authors: Qingya Wang, Chengjing Dang, Haoyu Liu and Jie Hui

The therapeutic effects of excimer laser coronary atherectomy therapy for in-stent restenosis chronic total occlusions

To evaluate the safety and efficacy of excimer laser coronary atherectomy (ELCA) in patients with in-stent restenosis chronic total occlusions (ISR CTOs).

Authors: Hui Li, Hu Ai, Le Li, Naixin Zheng, Guodong Tang, Guojian Yang, Ying Zhao, Fucheng Sun and Huiping Zhang

Validity and reliability of the Italian version of the cardiac quality of life questionnaire for pediatric patients with heart disease (PedsQLTM)

Congenital heart disease (CHD) accounts for nearly a third of all major congenital anomalies. Advances in pediatric cardiology shifted attention from mortality to morbidity and health-related quality of life (...

Authors: Teresa Grimaldi Capitello, Francesca Bevilacqua, Roberta Vallone, Anna Maria Dall’Oglio, Francesca Santato, Salvatore Giannico, Giulio Calcagni, Simone Piga, Marta Ciofi degli Atti, Simonetta Gentile and Angela Rossi

Electrocardiographic and electrophysiological characteristics of idiopathic ventricular arrhythmias with acute successful ablation at the superior portion of the mitral annulus

We sought to identify the electrocardiographic and electrophysiological characteristics of ventricular arrhythmias (VAs), including idiopathic ventricular tachycardia (VT) and premature ventricular contraction...

Authors: Chengye Di, Konstantinos P. Letsas, Peng Gao, Qun Wang, Yanxi Wu and Wenhua Lin

Increased ratio of sST2/LVMI predicted cardiovascular mortality and heart failure rehospitalization in heart failure with reduced ejection fraction patients: a prospective cohort study

Inflammation is one of the principal triggering mechanisms for left ventricular fibrosis and remodeling in heart failure, leading to adverse clinical outcomes. Soluble suppression of tumorigenicity 2 (sST2), a...

Authors: Fuhai Li, Mengying Xu, Mingqiang Fu, Xiaotong Cui, Zhexun Lian, Hui Xin, Jingmin Zhou and Junbo Ge

Adhesion of monocytes and endothelial cells isolated from the human aorta suppresses by miRNA-PEI particles

Knowledge of stenosis in coronary arteries requires an understanding of the cellular and molecular processes that occur throughout the leukocyte rolling process. In this study, the roles of miR-125a-5p and miR...

Authors: Adeleh Poursaleh, Farnaz Sadegh Beigee, Golnaz Esfandiari and Mohammad Najafi

Post cardiac injury syndrome successfully treated with medications: a report of two cases

Post cardiac injury syndrome (PCIS) is induced by myocardial infarction or cardiac surgery, as well as minor insults to the heart such as percutaneous coronary intervention (PCI), or insertion of a pacing lead...

Authors: Mu-Shiang Huang, Yan-Hua Su and Ju-Yi Chen

Hypertriglyceridemia impact on arterial parameters in patients with metabolic syndrome

The development of metabolic syndrome (MS) augments risk for atherosclerotic cardiovascular disease (CVD), but pathophysiological mechanisms of this relation are still under discussion. Overlapping CVD risk fa...

Authors: Egidija Rinkūnienė, Vilma Dženkevičiūtė, Žaneta Petrulionienė, Eglė Majauskienė, Ligita Ryliškytė, Roma Puronaitė, Jolita Badarienė, Rokas Navickas and Aleksandras Laucevičius

Clinical features and risk factors of postoperative in-hospital mortality following surgical repair of Stanford type A acute aortic dissection

To investigate the clinical features of patients with Stanford type A acute aortic dissection (AAD) and analyze the risk factors affecting postoperative in-hospital mortality rate.

Authors: Chen Ke, Hao Wu, Min Xi, Wei Shi, Qihong Huang and Guirong Lu

Association between cytochrome P450 2C19 polymorphism and clinical outcomes in clopidogrel-treated Uygur population with acute coronary syndrome: a retrospective study

Acute coronary syndrome (ACS) has become a vital disease with high mortality in the Uygur populations. Clopidogrel plays an important role in reducing the risk of recurrent cardiovascular events after ACS; how...

Authors: Luhai Yu, Tingting Wang, Huidong Bai, Weijiang Zhu, Yanju Li, Jianhua Wu, Wenli Liu, Li Sun, Aiping Yu and Hongjian Li

Declined ELABELA plasma levels in hypertension patients with atrial fibrillation: a case control study

Atrial fibrillation (AF) is a common arrhythmia in patients with hypertension. ELABELA, which has cardioprotective effects, is decreased in the plasma of patients with hypertension and might be associated with...

Authors: Zheng Ma, Lei Zhao, Ye-ping Zhang, Jiu-chang Zhong and Xin-chun Yang

Left ventricular inflow obstruction due to a coronary arteriovenous fistula: a paediatric case report

We report a rare case of left ventricular inflow obstruction from a branch of the left circumflex coronary artery to the right atrium caused by a coronary arteriovenous fistula (CAVF) in a young Japanese male ...

Authors: Ayako Chida-Nagai, Hirokuni Yamazawa, Takao Tsujioka, Kota Taniguchi, Osamu Sasaki, Gaku Izumi, Nobuyasu Kato and Atsuhito Takeda

Renal denervation in a patient with a highly tortuous renal artery using a guide extension catheter: a case report

Catheter-based renal denervation (RDN) has been introduced to treat resistant hypertension. Although the technology of RDN has been largely improved, denervation of tortuous renal arteries remains challenging.

Authors: Peijiang Wang, Jindong Wan, Jixin Hou, Sen Liu and Fei Ran

Comparison of lesion characteristics between conventional and high-power short-duration ablation using contact force-sensing catheter in patients with paroxysmal atrial fibrillation

Transmural lesion creation is essential for effective atrial fibrillation (AF) ablation. Lesion characteristics between conventional energy and high-power short-duration (HPSD) setting in contact force-guided ...

Authors: Chun-Chao Chen, Po-Tseng Lee, Vu Van Ba, Chieh-Mao Chuang, Yenn-Jiang Lin, Li-Wei Lo, Yu-Feng Hu, Fa-Po Chung, Chin-Yu Lin, Ting-Yung Chang, Jennifer Jeanne Vicera, Ting-Chun Huang, Chih-Min Liu, Cheng-I Wu, Isaiah C. Lugtu, Ankit Jain…

Comparative effect of statin intensity between prediabetes and type 2 diabetes mellitus after implanting newer-generation drug-eluting stents in Korean acute myocardial infarction patients: a retrospective observational study

Comparative studies regarding the long-term clinical outcomes of statin intensity between acute myocardial infarction (AMI) patients with prediabetes and those with type 2 diabetes mellitus (T2DM), after succe...

Authors: Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong and Yangsoo Jang

Association between eNOS rs1799983 polymorphism and hypertension: a meta-analysis involving 14,185 cases and 13,407 controls

Essential hypertension is a complex disease determined by the interaction of genetic and environmental factors, eNOS is considered to be one of the susceptible genes for hypertension. Our study aimed to evaluate ...

Authors: Jikang Shi, Siyu Liu, Yanbo Guo, Sainan Liu, Jiayi Xu, Lingfeng Pan, Yueyang Hu, Yawen Liu and Yi Cheng

Demographic, clinical, and functional determinants of antithrombotic treatment in patients with nonvalvular atrial fibrillation

This study assessed the sociodemographic, functional, and clinical determinants of antithrombotic treatment in patients with nonvalvular atrial fibrillation (NVAF) attended in the internal medicine setting.

Authors: Jose María Mostaza, Carmen Suarez, Jose María Cepeda, Luis Manzano and Demetrio Sánchez

Non-specific pain and 30-day readmission in acute coronary syndromes: findings from the TRACE-CORE prospective cohort

Patients with acute coronary syndromes often experience non-specific (generic) pain after hospital discharge. However, evidence about the association between post-discharge non-specific pain and rehospitalizat...

Authors: Jinying Chen, Catarina I. Kiefe, Marc Gagnier, Darleen Lessard, David McManus, Bo Wang and Thomas K. Houston

Myocardial bridging of the left anterior descending coronary artery as a risk factor for atrial fibrillation in patients with hypertrophic obstructive cardiomyopathy: a matched case–control study

Myocardial bridging (MB) is associated with various forms of arrhythmia. However, whether MB is a risk factor for atrial fibrillation (AF) in patients with hypertrophic obstructive cardiomyopathy (HOCM) remain...

Authors: Changrong Nie, Changsheng Zhu, Qiulan Yang, Minghu Xiao, Yanhai Meng and Shuiyun Wang

The correlation between patent foramen ovale and brain ischemia in plateau residents

It has been suggested that patent foramen ovale (PFO) contributes to the majority of cryptogenic stroke cases in young people, however, the direct link is still undetermined. Here we analyzed the correlation b...

Authors: Gang Liu, Zhao Feng, Fan Feng, Changju Xue, Fei Liu and Xiaoting Xie

Chest pain in a mid-aged woman, not simply myopericarditis: a case report of anti-Ku positive polymyositis

Anti-Ku is a rare antibody which can be positive in some rheumatic diseases and it might be related to cardiac involvement. Polymyositis is an inflammatory myopathy, and its cardiac involvement seldom presents...

Authors: Weiping Tan, Bin Dong, Jincui Gu, Yang Peng and Ruicong Xue

Time-to-event prediction analysis of patients with chronic heart failure comorbid with atrial fibrillation: a LightGBM model

Chronic heart failure (CHF) comorbid with atrial fibrillation (AF) is a serious threat to human health and has become a major clinical burden. This prospective cohort study was performed to design a risk strat...

Authors: Chu Zheng, Jing Tian, Ke Wang, Linai Han, Hong Yang, Jia Ren, Chenhao Li, Qing Zhang, Qinghua Han and Yanbo Zhang

The elevated expression of TLR4 and MMP9 in human abdominal aortic aneurysm tissues and its implication

Toll-like receptor 4 (TLR4) and matrix metalloproteinase 9 (MMP9) have been investigated to play significant roles in the formation of abdominal aortic aneurysm (AAA). But the reports on the expression pattern...

Authors: Tan Li, Xintong Li, Xiaozheng Liu, Jun Yang and Chunyan Ma

Rare double orifice mitral valve malformation associated with bicuspid aortic valve in Turner syndrome: diagnosed by a series of novel three-dimensional echocardiography and literature review

Patients with both double orifice mitral valve (DOMV) and bicuspid aortic valve (BAV) malformation are rare. Although DOMV or BAV can be detected in some genetic syndromes, it has not been reported to simultan...

Authors: Feifei Sun, Xueying Tan, Aijiao Sun, Xintong Zhang, Yanxiao Liang and Weidong Ren

Perimyocarditis following first dose of the mRNA-1273 SARS-CoV-2 (Moderna) vaccine in a healthy young male: a case report

Half of U.S. adults have received at least one dose of the COVID-19 vaccines produced by either Pfizer, Moderna, or Johnson and Johnson, which represents a major milestone in the ongoing pandemic. Given the em...

Authors: Ammar A. Hasnie, Usman A. Hasnie, Nirav Patel, Muhammad U. Aziz, Min Xie, Steven G. Lloyd and Sumanth D. Prabhu