Articles

The association between platelet-to-lymphocyte ratio with mortality among patients suffering from acute decompensated heart failure

Platelet-to-lymphocyte ratio (PLR) is an inflammation index suggested to have the prognostic capability in heart failure (HF). We sought to investigate the association of PLR with cardiovascular disease (CVD) ...

Authors: Maryam Heidarpour, Sepideh Bashiri, Mehrbod Vakhshoori, Kiyan Heshmat-Ghahdarijani, Farbod Khanizadeh, Shaghayegh Ferdowsian and Davood Shafie

Prognostic implications of valvular heart disease in patients with non-valvular atrial fibrillation

Valvular heart disease (VHD) in non-valvular atrial fibrillation (AF) is a puzzling clinical entity. The aim of this study was to evaluate the prognostic effect of significant VHD (sVHD) among patients with no...

Authors: Athanasios Samaras, Eleni Vrana, Anastasios Kartas, Dimitrios V. Moysidis, Andreas S. Papazoglou, Ioannis Doundoulakis, George Fotos, Georgios Rampidis, Dimitrios G. Tsalikakis, Georgios Efthimiadis, Haralambos Karvounis, Apostolos Tzikas and George Giannakoulas

A real-world study on diagnosis and prognosis of light-chain cardiac amyloidosis in Southern China

Light-chain cardiac amyloidosis (AL-CA) has been highly valued in developed countries, but in developing countries, the recognition and diagnosis of this condition is still limited. There are currently few rep...

Authors: Zhijian Wu, Muzheng Li, Tudahun Ilyas, Wei Li, Mu Zeng, Fang Li, Yanxia Liu, Mingxian Chen, Yaqin Chen, Qingyi Zhu, Nenghua Qi, Qiming Liu and Jianjun Tang

Delayed coronary artery occlusion after transcatheter aortic valve replacement and chimney stenting: a case report

Delayed coronary artery occlusion (CAO) is a rare but fatal complication after transcatheter aortic valve replacement, chimney stenting is the standard technique for established CAO or impending CAO.

Authors: Hui Li, Wenduo Zhang, Bo Xia, Fucheng Sun, Jiefu Yang and Huiping Zhang

Reverse remodeling of tricuspid valve morphology and function in chronic thromboembolic pulmonary hypertension patients following pulmonary thromboendarterectomy: a cardiac magnetic resonance imaging and invasive hemodynamic study

To investigate changes in tricuspid annulus (TA) and tricuspid valve (TV) morphology among chronic thromboembolic pulmonary hypertension (CTEPH) patients before and 12 months after pulmonary thromboendarterect...

Authors: Christian Alcaraz Frederiksen, Farhad Waziri, Steffen Ringgaard, Søren Mellemkjær, Tor Skibsted Clemmensen, Vibeke Elisabeth Hjortdal, Sten Lyager Nielsen and Steen Hvitfeldt Poulsen

Ruptured sinus of valsalva aneurysm presenting as syncope and hypotension: a case report

Unruptured sinus of valsalva aneurysm (SOVA) are typically asymptomatic, and hence can be easily ignored. Ruptured sinus of valsalva aneurysm (RSOVA) usually protrude into the right atrium or ventricular. Howe...

Authors: Guang Ying Zhuo, Pei Yong Zhang, Li Luo, Qian Tang and Tao Xiang

Proteome-scale profiling reveals MAFF and MAFG as two novel key transcription factors involved in palmitic acid-induced umbilical vein endothelial cell apoptosis

Vascular endothelial cell apoptosis is the leading risk factor of atherosclerosis (AS). The purpose of our study was to use a new generation high-throughput transcription factor (TF) detection method to identi...

Authors: Mangyuan Wang, Fen Liu, Binbin Fang, Qiang Huo and Yining Yang

Capnometric feedback training decreases 24-h blood pressure in hypertensive postmenopausal women

High normal resting pCO₂ is a risk factor for salt sensitivity of blood pressure (BP) in normotensive humans and has been associated with higher resting systolic BP in postmenopausal women. To date, however, no k...

Authors: David E. Anderson, Alexis N. Reeves, Wolf E. Mehling and Margaret A. Chesney

Risk factors for revascularization and in-stent restenosis in patients with triple-vessel disease after second-generation drug-eluting stent implantation: a retrospective analysis

Coronary artery disease (CAD) is a common cardiac disease with high morbidity and mortality, and triple-vessel disease (TVD) is a severe type of CAD. This study investigated risk factors for revascularization ...

Authors: MengYing Zeng, XiaoWei Yan and Wei Wu

The role of brain natriuretic peptide in atrial fibrillation: a substudy of the Substrate Modification with Aggressive Blood Pressure Control for Atrial Fibrillation (SMAC-AF) trial

Catheter ablation is an established therapy for atrial fibrillation but is limited by recurrence; efforts have been made to identify biomarkers that predict recurrence. We investigated the effect of baseline N...

Authors: Willy Weng, Rajin Choudhury, John Sapp, Anthony Tang, Jeff S. Healey, Isabelle Nault, Lena Rivard, Isabelle Greiss, Jordan Bernick and Ratika Parkash

The impact of antihypertensive treatment initiation on health-related quality of life and cardiovascular risk factor levels: a prospective, interventional study

Effective prevention and treatment of hypertension is one of the most potential interventions in terms of preventing cardiovascular deaths and disabilities. However, the treatment control is often poor. This m...

Authors: Aapo Tahkola, Päivi Korhonen, Hannu Kautiainen, Teemu Niiranen and Pekka Mäntyselkä

Identification of key miRNAs and mRNAs related to coronary artery disease by meta-analysis

To illustrate the mechanism of miRNA and mRNA in coronary artery diseasen (CAD), differentially expressed microRNAs (DEmiRNAs) and genes (DEGs) were analyzed.

Authors: Long Liu, Jingze Zhang, Mei Wu and Haiming Xu

Left atrial appendage orifice area and morphology is closely associated with flow velocity in patients with nonvalvular atrial fibrillation

Thromboembolic events are the most serious complication of atrial fibrillation (AF), and the left atrial appendage (LAA) is the most important site of thrombosis in patients with AF. During the period of COVID...

Authors: Lei Chen, Changjiang Xu, Wensu Chen and Chaoqun Zhang

Interaction between gender and post resuscitation interventions on neurological outcome in an asphyxial rat model of cardiac arrest

Previous clinical studies have suggested an effect of gender on outcome after out-of-hospital cardiac arrest, but the results are conflicting and there is no uniform agreement regarding gender differences in s...

Authors: Jianjie Wang, Jingru Li, Bihua Chen, Yiming Shen, Juan Wang, Kaifa Wang, Changlin Yin and Yongqin Li

Resistance exercise affects catheter-related thrombosis in rats through miR-92a-3p, oxidative stress and the MAPK/NF-κB pathway

MiR-92a-3p and oxidative stress are associated with catheter-related thrombosis (CRT). As a kind of physical intervention, resistance exercise can effectively promote blood circulation. In this study, we inves...

Authors: Cui Wen, Yanping Ying, Huihan Zhao, Qingjuan Jiang, Xiao Gan, Yan Wei, Jiani Wei and Xinxin Huang

Predictive value of CHADS₂ and CHA₂DS₂-VASc scores for coronary artery lesions and in-hospital prognosis of patients with acute ST-segment elevation myocardial infarction

To evaluate the predictive value of CHADS₂ and CHA₂DS₂-VASc scores for coronary artery lesions and in-hospital prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI).

Authors: Xiaoli Li, Zhen Zeng, Xinchun Yang and Hongjiang Wang

Risk factors of in-stent restenosis among coronary artery disease patients with syphilis undergoing percutaneous coronary intervention: a retrospective study

The risk factors of in-stent restenosis (ISR) among coronary artery disease (CAD) patients with syphilis after percutaneous coronary intervention (PCI) are not fully understood. Therefore, this study aimed to ...

Authors: Ling Zhang, Yu Wang, Zhe Zhang, Hongyuan Liang, Liang Wu, Liang Ni, Guiju Gao, Di Yang, Hongxin Zhao and Jiang Xiao

Construction and investigation of a circRNA-associated ceRNA regulatory network in Tetralogy of Fallot

As the most frequent type of cyanotic congenital heart disease (CHD), tetralogy of Fallot (TOF) has a relatively poor prognosis without corrective surgery. Circular RNAs (circRNAs) represent a novel class of e...

Authors: Haifei Yu, Xinrui Wang and Hua Cao

Adhesion pathway proteins and risk of atrial fibrillation in the Multi-Ethnic Study of Atherosclerosis

The cellular adhesion pathway has been suggested as playing an important role in the pathogenesis of atrial fibrillation (AF). However, prior studies that have investigated the role of adhesion pathway protein...

Authors: Israel J. Mendez, Sheila M. Manemann, Elizabeth J. Bell, Nicholas B. Larson, Paul A. Decker, Marco A. Guerrero, Naomi Q. Hanson, Susan R. Heckbert, James S. Pankow, Michael Y. Tsai and Suzette J. Bielinski

Development and validation of a risk prediction nomogram for in-stent restenosis in patients undergoing percutaneous coronary intervention

This study aimed to develop and validate a nomogram to predict probability of in-stent restenosis (ISR) in patients undergoing percutaneous coronary intervention (PCI).

Authors: Wenbo He, Changwu Xu, Xiaoying Wang, Jiyong Lei, Qinfang Qiu, Yingying Hu and Da Luo

The impact of COVID-19 pandemic on aortic valve surgical service: a single centre experience

The coronavirus-disease 2019 (COVID-19) pandemic imposed an unprecedented burden on the provision of cardiac surgical services. The reallocation of workforce and resources necessitated the postponement of elec...

Authors: Dimitrios Vlastos, Ishaansinh Chauhan, Kwabena Mensah, Maria Cannoletta, Athanasios Asonitis, Ahmed Elfadil, Mario Petrou, Anthony De Souza, Cesare Quarto, Sunil K. Bhudia, Ulrich Rosendahl, John Pepper and George Asimakopoulos

MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1

A high level of total cholesterol is associated with several lipid metabolism disorders, including atherosclerosis and cardiovascular diseases. ATP-binding cassette (ABC) transporter A1 (ABCA1) and miR-33-5p p...

Authors: Qiong Xie, Jianqiang Peng, Ying Guo and Feng Li

Dietary acid load and risk of cardiovascular disease: a prospective population-based study

Considering the inconsistencies in the cardiovascular effects of dietary acid load and the impact of dietary acidity on the acid–base homeostasis within the body, we aimed to assess the association of dietary ...

Authors: Parvin Mirmiran, Zeinab Houshialsadat, Zahra Bahadoran, Sajjad Khalili‑Moghadam, Mohammad Karim Shahrzad and Fereidoun Azizi

Risk factors and in-hospital mortality of postoperative hyperlactatemia in patients after acute type A aortic dissection surgery

Hyperlactatemia may be caused by increased production due to tissue hypoxia or non-hypoxia. The aim of this study was first to identify risk factors for postoperative hyperlactatemia (POHL) after Stanford type...

Authors: Su Wang, Dashuai Wang, Xiaofan Huang, Hongfei Wang, Sheng Le, Jinnong Zhang and Xinling Du

Takotsubo syndrome as an overlooked and elusive cause of a single episode of dyspnea in young women: a case report

Dyspnea is a common symptom in patients presenting to the emergency department. It has a variety of causes that range from non-urgent to life-threatening. One episode of dyspnea in a healthy young person is ea...

Authors: Sung Eun Lee, Seung-Hyun Yoon, Hyo Jung Kang and Jung Hwan Ahn

Distribution characteristics and influencing factors of homocyteine in an apparently healthy examined population

Homocysteine (Hcy) is considered to be a risk factor for cardiovascular and cerebrovascular diseases. Few studies have evaluated the distribution of Hcy on a large-scale health examination. Accordingly, this s...

Authors: Fang Bao, Ming Cui, Xiuying Shi, Shaoqing Ju and Hui Cong

Custom-made fenestrated stent for mycotic aortic aneurysms: a report of two cases

Mycotic aortic aneurysm is a rare and potentially life-threatening lesion, and endovascular repair has become increasingly accepted for intervention. Fenestrated endografts are available options to treat aneur...

Authors: Siting Li, Mengyin Chen, Yuehong Zheng, Zhili Liu and Rong Zeng

The role of multimodality imaging in diagnosing acute perimyocarditis secondary to Crohn’s disease

Acute perimyocarditis is a rare extra-intestinal manifestation in Crohn’s disease which required multimodality imaging to confirm the diagnosis. Here we present a case of acute perimyocarditis as the first pre...

Authors: Hawani Sasmaya Prameswari, Iswaree Devi Balakrishnan, Chun Yuan Khoo, Loon Yee Teo, Lihua Laura Chan and Choon Ta Ng

Medical cannabis authorization and the risk of cardiovascular events: a longitudinal cohort study

Cannabis is increasingly used for therapeutic purpose. However, its safety profile is not well known. This study assessed the risk of cardiovascular-related emergency department (ED) visit and hospitalization ...

Authors: Arsene Zongo, Cerina Lee, Jason R. B. Dyck, Jihane El-Mourad, Elaine Hyshka, John G. Hanlon and Dean T. Eurich

Clinical characteristics and therapeutic strategy of frequent accelerated idioventricular rhythm

Accelerated idioventricular rhythm (AIVR) is often transient, considered benign and requires no treatment. This observational study aims to investigate the clinical manifestations, treatment, and prognosis of ...

Authors: Lan Wang, Hailei Liu, Chao Zhu, Kai Gu, Gang Yang, Hongwu Chen, Weizhu Ju, Mingfang Li, Fengxiang Zhang, Bing Yang, Dao Wu Wang and Minglong Chen

Relationship between serum lipid levels and ischemic stroke in patients with atrial fibrillation: a nested case–control study based on the China Atrial Fibrillation Registry

Atrial fibrillation (AF) is an important risk factor for acute ischemic stroke.

Authors: Fei Li, Xin Du, Liu He, Chao Jiang, Shijun Xia, Changsheng Ma and Jianzeng Dong

Clinical prediction scores and early anticoagulation therapy for new-onset atrial fibrillation in critical illness: a post-hoc analysis

This study sought to describe the epidemiology of anticoagulation therapy for critically ill patients with new-onset atrial fibrillation (NOAF) according to CHA2DS2-VASc and HAS-BLED scores and to assess the e...

Authors: Masaaki Sakuraya, Takuo Yoshida, Yusuke Sasabuchi, Shodai Yoshihiro and Shigehiko Uchino

Accuracy of neutrophil to lymphocyte and monocyte to lymphocyte ratios as new inflammatory markers in acute coronary syndrome

Inflammation plays a key role in the development of atherosclerosis and in the pathogenesis of acute coronary syndrome (ACS). Leukocytes and leukocytes ratios were recognized as inflammatory markers in predict...

Authors: Ahmed Mohammed Shumilah, Arwa Mohammed Othman and Anwar Kasim Al-Madhagi

Is obstructive sleep apnoea associated with hypoxaemia and prolonged ICU stay after type A aortic dissection repair? A retrospective study in Chinese population

Although obstructive sleep apnoea (OSA) is prevalent among patients with aortic dissection, its prognostic impact is not yet determined in patients undergoing major vascular surgery. We aimed to investigate th...

Authors: Xin Xi, Yu Chen, Wei-Guo Ma, Jiang Xie, Yong-Min Liu, Jun-Ming Zhu, Ming Gong, Guang-Fa Zhu and Li-Zhong Sun

Individual and combined association analysis of famine exposure and serum uric acid with hypertension in the mid-aged and older adult: a population-based cross-sectional study

Malnutrition in early life may affect health in later life. The associations between malnutrition and serum uric acid (SUA) and hypertension were inconsistent. The present study aimed to investigate the indivi...

Authors: Lin Zhang, Liu Yang, Congzhi Wang, Ting Yuan, Dongmei Zhang, Huanhuan Wei, Jing Li, Yunxiao Lei, Lu Sun, Xiaoping Li, Ying Hua, Hengying Che and Yuanzhen Li

Predicting the 10-year risk of cardiovascular diseases and its relation to healthy diet indicator in Iranian military personnel

Epidemiological studies indicate increased prevalence of cardiovascular disease (CVD) among military personnel. Accordingly, identification of at-risk individuals and lifestyle modification such as improving d...

Authors: Karim Parastouei, Mojtaba Sepandi and Eslam Eskandari

Perioperative risk factors for new-onset postoperative atrial fibrillation after coronary artery bypass grafting: a systematic review

Postoperative atrial fibrillation (POAF) is the most common cardiac dysrhythmia to occur after coronary artery bypass grafting (CABG). However, the risk factors for new-onset POAF after CABG during the periope...

Authors: Eun Ji Seo, Joonhwa Hong, Hyeon-Ju Lee and Youn-Jung Son

Prediction of cardiovascular risk in patients with chronic obstructive pulmonary disease: a study of the National Health and Nutrition Examination Survey database

Cardiovascular disease (CVD) is a common comorbidity associated with chronic obstructive pulmonary disease (COPD), but few studies have been conducted to identify CVD risk in COPD patients. This study was to d...

Authors: Yun Shi, Jing Zhang and Yingshuo Huang

Exploring the diagnostic effectiveness for myocardial ischaemia based on CCTA myocardial texture features

To explore the characteristics of myocardial textures on coronary computed tomography angiography (CCTA) images in patients with coronary atherosclerotic heart disease, a classification model was established, ...

Authors: Hengyu Zhao, Lijie Yuan, Zhishang Chen, Yuting Liao and Jiangzhou Lin

Evaluation of Tp-e interval, Tp-e/QT ratio and index of cardiac-electrophysiological balance in patients with tinnitus

Tinnitus is a common auditory symptom. Dysfunction in the autonomic nervous system (ANS) is an essential part of the etiopathogenesis of tinnitus. ANS regulates heart rate and heart rhythm and can lead to vent...

Authors: Hakan Kaya, Arif Suner, Mehtap Koparal, S. Cem Yucetas and Safiye Kafadar

Clinical characteristics and prognostic implications of diabetes and myocardial injury in patients admitted to the emergency room

This study aimed to investigate the clinical features and prognosis of diabetes and myocardial injury in patients admitted to the emergency department.

Authors: Gil Bonet, Anna Carrasquer, Óscar M. Peiró, Raul Sanchez-Gimenez, Nisha Lal-Trehan, Victor del-Moral-Ronda, Isabel Fort-Gallifa and Alfredo Bardají

Aortic root aortopathy in bicuspid aortic valve associated with high genetic risk

The bicuspid aortic valve (BAV) is prone to ascending aortic dilatation (AAD) involving both the tubular segment and the aortic root. The genetic factor was proposed as one of the most important mechanisms for...

Authors: Mingjia Ma, Zongzhe Li, Mohamed Abdulkadir Mohamed, Ligang Liu and Xiang Wei

Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison

Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain.

Authors: Ali Sheikhy, Aida Fallahzadeh, Saeed Sadeghian, Khalil Forouzannia, Jamshid Bagheri, Abbas Salehi-Omran, Masih Tajdini, Arash Jalali, Mina Pashang and Kaveh Hosseini

Health status measured by Kansas City Cardiomyopathy Questionnaire-12 in primary prevention implantable cardioverter defibrillator patients with heart failure

Self-reported health status as measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ) in patients with primary prevention implantable cardioverter defibrillators (ICDs) has mainly been reported from r...

Authors: Gustav Mattsson, Marita Wallhagen and Peter Magnusson

Cardiology providers’ recommendations for treatments and use of patient decision aids for multivessel coronary artery disease

Rates of recommending percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) vary across clinicians. Whether clinicians agree on preferred treatment options for multivessel coronar...

Authors: Elizabeth L. Nichols, Glyn Elwyn, Anthony DiScipio, Mandeep S. Sidhu, A. James O’Malley, Daniel D. Matlock, Shama Alam, Cathy S. Ross, Megan Coylewright, David J. Malenka and Jeremiah R. Brown

Outcomes of women with congenital heart disease admitted to acute-care hospitals for delivery in Japan: a retrospective cohort study using nationwide Japanese diagnosis procedure combination database

The number of women with congenital heart disease (CHD) who are of childbearing age is increasing due to advancements in medical management. Nonetheless, data on the outcomes of delivery in women with CHD rema...

Authors: Manabu Nitta, Sayuri Shimizu, Makoto Kaneko, Kiyohide Fushimi and Shinichiro Ueda

Case report: Diagnosis and emergency surgery on a young patient with extensive aortic dissection without any risk factors

Type A aortic dissection is a very dangerous, fatal, and emergency condition for surgery. Acute aortic dissection is a rare condition, such that many patients will not survive without reconstructive surgery.

Authors: Masoud Shafiee, Mohsen Shafiee, Noorollah Tahery, Omid Azadbakht, Zeinab Nassari and Reza Baghbani

Implementation of a zero fluoroscopic workflow using a simplified intracardiac echocardiography guided method for catheter ablation of atrial fibrillation, including repeat procedures

Pulmonary vein isolation (PVI) is the cornerstone of the interventional treatment of atrial fibrillation (AF). Traditionally, during these procedures the catheters are guided by fluoroscopy, which poses a risk...

Authors: Tamas Tahin, Adam Riba, Barnabas Nemeth, Ferenc Arvai, Geza Lupkovics, Gabor Szeplaki and Laszlo Geller

Correction to: Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7

Authors: Elisabeth Pedersen, Beate Hennie Garcia, Kjell H. Halvorsen, Anne Elise Eggen, Henrik Schirmer and Marit Waaseth

Giant right atrium, what does it hide? Case presentation

Malformation of the right atrium is a rare cardiac abnormality and is usually reported as isolated malformation in the literature.

Authors: María Martín Talavera, Israel Valverde Pérez and Begoña Manso García