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  1. To investigate the relationship between obstructive sleep apnea (OSA) severity and high-sensitivity C-reactive protein (Hs-CRP), and their respective impact on the clinical outcomes in patients undergoing off-...

    Authors: Mingxin Gao, Kangjun Fan, Wenyuan Yu, Hongli Liu, Yongxiang Wei and Yang Yu
    Citation: BMC Cardiovascular Disorders 2021 21:366
    Content type: Research article Published on:

  2. Cardiac arrest (CA) in children is a major public health problem. Thanks to advances in cardiopulmonary resuscitation (CPR) guidelines and teaching skills, results in children have improved. However, pediatric...

    Authors: Jimena del Castillo, Débora Sanz, Laura Herrera and Jesús López-Herce
    Citation: BMC Cardiovascular Disorders 2021 21:365
    Content type: Study protocol Published on:

  3. In terms of cardiovascular magnetic resonance are haematocrit values required for calculation of extracellular volume fraction (ECV). Previously published studies have hypothesized that haematocrit could be ca...

    Authors: Lukas Opatril, Roman Panovsky, Jan Machal, Tomas Holecek, Lucia Masarova, Vera Feitova, Vladimir Kincl, Marek Hodejovsky and Lenka Spinarova
    Citation: BMC Cardiovascular Disorders 2021 21:363
    Content type: Research Published on:

  4. Previous studies proposed that chronic inflammation in diabetes has a role in abnormal collagen production and elastin degradation, which promotes arterial stiffness. Monocyte-to-High Density Lipoprotein chole...

    Authors: Dyah Samti Mayasari, Nahar Taufiq and Hariadi Hariawan
    Citation: BMC Cardiovascular Disorders 2021 21:362
    Content type: Research article Published on:

  5. In recent years, there has been greater recognition of the important role of community health volunteers in many countries and their important role informs many health programs. This include health education, ...

    Authors: Elvis Safary, Micrina Mwandeti, Beatrice Matanje, Claudia Beiersmann, Caroline Mtaita, Veronica Shiroya, Volker Winkler, Andreas Deckert, Pratap Kumar, Sam Phiri and Florian Neuhann
    Citation: BMC Cardiovascular Disorders 2021 21:361
    Content type: Research Published on:

  6. The interventional treatment of calcified lesions with severe tortuosity in the left anterior descending artery (LAD) was challenging and the report of rotational atherectomy with mother-and-child technique ha...

    Authors: Taichi Kato, Masashi Fujino, Kensuke Takagi and Teruo Noguchi
    Citation: BMC Cardiovascular Disorders 2021 21:360
    Content type: Case report Published on:

  7. It is difficult to evaluate the risk of patients with severe renal dysfunction before surgery due to various limitations despite high postoperative cardiac events. This study aimed to investigate the value of ...

    Authors: Hyun Jun Cho, Namkyun Kim, Hyeon Jeong Kim, Bo Eun Park, Hong Nyun Kim, Se Yong Jang, Myung Hwan Bae, Jang Hoon Lee, Dong Heon Yang, Hun Sik Park, Yongkeun Cho and Shung Chull Chae
    Citation: BMC Cardiovascular Disorders 2021 21:359
    Content type: Research Published on:

  8. Transcatheter aortic valve replacement (TAVR) has gained increasing acceptance for patients with aortic disease. Both transfemoral (TF-TAVR) and transapical (TA-TAVR) approach were widely adopted while their p...

    Authors: Ruikang Guo, Minghui Xie, Wai Yen Yim, Wenconghui Wu, Weiwei Jiang, Yin Wang and Xingjian Hu
    Citation: BMC Cardiovascular Disorders 2021 21:358
    Content type: Review Published on:

  9. Many patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) are discharged without a known aetiology for their clinical presentation. This study sought to assess the effect of this...

    Authors: T. F. S. Pustjens, A. Meerman, N. P. A. Vranken, A. W. Ruiters, B. Gho, M. Stein, M. Ilhan, L. Veenstra, P. Winkler, Á. Lux, S. Rasoul and A. W. J. van ‘t Hof
    Citation: BMC Cardiovascular Disorders 2021 21:357
    Content type: Research Published on:

  10. Activating transcription factor 3 (ATF3) is an early response gene that is activated in response to atherosclerotic stimulation and may be an important factor in inhibiting the progression of atherosclerosis. ...

    Authors: J. Peng, C. Y. Le, B. Xia, J. W. Wang, J. J. Liu, Z. Li, Q. J. Zhang, Q. Zhang, J. Wang and C. W. Wan
    Citation: BMC Cardiovascular Disorders 2021 21:356
    Content type: Research Published on:

  11. Rheumatic heart disease (RHD) is still a concerning issue in developing countries. Among delayed RHD presentations, rheumatic mitral valve stenosis (MS) remains a prevalent finding. Percutaneous transvenous mi...

    Authors: Yahya Dadjo, Maryam Moshkani Farahani, Reza Nowshad, Mohsen Sadeghi Ghahrodi, Alireza Moaref and Javad Kojuri
    Citation: BMC Cardiovascular Disorders 2021 21:355
    Content type: Research article Published on:

  12. This study aimed to assess the rate of concordance, and to investigate sources of non-concordance of recommendations in the management of hypertension across CPGs in Southeast Asia, with internationally reputa...

    Authors: Chia Siang Kow, Syed Shahzad Hasan, Pei Se Wong and Rohit Kumar Verma
    Citation: BMC Cardiovascular Disorders 2021 21:354
    Content type: Research Published on:

  13. Indoleamine 2,3 dioxygenase (IDO), the rate-limiting enzyme in the kynurenine (Kyn) pathway of tryptophan (Trp) degradation, is modulated by inflammation, and is regarded as a key molecule driving immunotolera...

    Authors: Nattawut Wongpraparut, Ploy Pengchata, Sudarat Piyophirapong, Pariya Panchavinnin, Rungtiwa Pongakasira, Noppadol Arechep, Kanda Kasetsinsombat and Kittipong Maneechotesuwan
    Citation: BMC Cardiovascular Disorders 2021 21:353
    Content type: Research article Published on:

  14. We examined the relationship between ratios of select biomarkers of kidney and liver function on all-cause and coronary heart disease (CHD) mortality, both in isolation, and in combination with metabolic syndr...

    Authors: Akinkunle Oye-Somefun, Jennifer L. Kuk and Chris I. Ardern
    Citation: BMC Cardiovascular Disorders 2021 21:352
    Content type: Research Published on:

  15. CVD is the leading cause of death in T2DM patients. However, few biomarkers have been identified to detect and diagnose CVD in the early stage of T2DM. The aim of our study was to identify the important mRNAs,...

    Authors: Zhiyuan Fan, Wenjuan Peng, Zhiwen Wang, Ling Zhang and Kuo Liu
    Citation: BMC Cardiovascular Disorders 2021 21:351
    Content type: Research Published on:

  17. Authors: Nan Ye, Lijiao Yang, Guoqin Wang, Weijing Bian, Fengbo Xu, Changsheng Ma, Dong Zhao, Jing Liu, Yongchen Hao, Jun Liu, Na Yang and Hong Cheng
    Citation: BMC Cardiovascular Disorders 2021 21:349
    Content type: Correction Published on:

    The original article was published in BMC Cardiovascular Disorders 2020 20:380

  19. Sodium-glucose cotransporter 2 inhibitor (SGLT2i) reduces the risk of the composite renal endpoint and weakens the progressive decline in renal function in patients with chronic heart failure (HF). However, a ...

    Authors: Masaki Nakagaito, Teruhiko Imamura, Shuji Joho, Ryuichi Ushijima, Makiko Nakamura and Koichiro Kinugawa
    Citation: BMC Cardiovascular Disorders 2021 21:347
    Content type: Research article Published on:

  20. The relationship between the characteristics of cardiac implantable electronic device (CIED) leads and subclinical cardiac perforations remains unclear. This study aimed to evaluate the incidence of subclinica...

    Authors: Yeong-Min Lim, Jae-Sun Uhm, Min Kim, In-Soo Kim, Moo-Nyun Jin, Hee Tae Yu, Tae-Hoon Kim, Hye-Jeong Lee, Young-Jin Kim, Boyoung Joung, Hui-Nam Pak and Moon-Hyoung Lee
    Citation: BMC Cardiovascular Disorders 2021 21:346
    Content type: Research Published on:

  21. Atrial fibrillation (AF) is the most common cardiac arrhythmia in patients with chronic kidney disease (CKD) and acute coronary syndrome (ACS). This study aimed to explore the frequency and impact of AF on cli...

    Authors: Lijiao Yang, Nan Ye, Guoqin Wang, Weijing Bian, Fengbo Xu, Dong Zhao, Jing Liu, Yongchen Hao, Jun Liu, Na Yang and Hong Cheng
    Citation: BMC Cardiovascular Disorders 2021 21:345
    Content type: Research article Published on:

  22. Myocardial infarction (MI) contributes to high mortality and morbidity and can also accelerate atherosclerosis, thus inducing recurrent event due to status changing of coronary artery walls or plaques. The res...

    Authors: Qiang Zhang, Yue Zheng, Meng Ning and Tong Li
    Citation: BMC Cardiovascular Disorders 2021 21:344
    Content type: Research article Published on:

  23. Serum free fatty acid (FFA) concentrations are associated with coronary heart disease and diabetes mellitus (DM). Few studies focused on the relationship between serum FFA levels and coronary artery calcificat...

    Authors: Yangxun Xin, Junfeng Zhang, Yuqi Fan and Changqian Wang
    Citation: BMC Cardiovascular Disorders 2021 21:343
    Content type: Research article Published on:

  24. Health systems are increasingly using standardized social needs screening and response protocols including the Protocol for Responding to and Assessing Patients’ Risks, Assets, and Experiences (PRAPARE) to imp...

    Authors: Connor Drake, Tyler Lian, Justin G. Trogdon, David Edelman, Howard Eisenson, Morris Weinberger, Kristin Reiter and Christopher M. Shea
    Citation: BMC Cardiovascular Disorders 2021 21:342
    Content type: Research article Published on:

  25. Catheter ablation is widely used in atrial fibrillation (AF) management. In this study, we are aimed to investigate the incidence of postprocedural cognitive decline in a larger population undergoing AF ablati...

    Authors: Jing Zhang, Shi-Jun Xia, Xin Du, Chao Jiang, Yi-Wei Lai, Yu-Feng Wang, Zhao-Xu Jia, Liu He, Ri-Bo Tang, Jian-Zeng Dong and Chang-Sheng Ma
    Citation: BMC Cardiovascular Disorders 2021 21:341
    Content type: Research article Published on:

  26. Mobile health-based individualized interventions have shown potential effects in managing cardiovascular risk factors. This study aims to assess whether or not mHealth based individualized interventions delive...

    Authors: Yuling Chen, Meihua Ji, Ying Wu, Ying Deng, Fangqin Wu and Yating Lu
    Citation: BMC Cardiovascular Disorders 2021 21:340
    Content type: Study protocol Published on:

  27. The epidemiology of valvular heart disease (VHD) has changed markedly over the last 50 years worldwide, and the prevalence and features of VHD in China are unknown. The objective of this study was to investiga...

    Authors: Ying Yang, Zengwu Wang, Zuo Chen, Xin Wang, Linfeng Zhang, Suning Li, Congyi Zheng, Yuting Kang, Linlin Jiang, Zhenhui Zhu and Runlin Gao
    Citation: BMC Cardiovascular Disorders 2021 21:339
    Content type: Research Published on:

  28. Early adoption of a healthy lifestyle has positive effects on cardiovascular health (CVH) in adulthood. In this study, we aimed to assess CVH metrics in a cohort of healthy teenagers with focus on differences ...

    Authors: C. Hochmayr, J. P. Ndayisaba, N. Gande, A. Staudt, B. Bernar, K. Stock, R. Geiger, M. Knoflach and U. Kiechl-Kohlendorfer
    Citation: BMC Cardiovascular Disorders 2021 21:338
    Content type: Research Published on:

  29. Predictive value of creatine kinase MB (CK-MB) for contrast-induced acute kidney injury (CI-AKI) among myocardial infarction (MI) patients has rarely been reported. We aim to evaluate the predictive value of C...

    Authors: Wen Wei, Lingyu Zhang, Yunhan Zhang, Ronghui Tang, Miao Zhao, Zhidong Huang, Jin Liu, Danyuan Xu, Yibo He, Bo Wang, Haozhang Huang, Qiang Li, Mengfei Lin, Yong Liu, Kaihong Chen and Shiqun Chen
    Citation: BMC Cardiovascular Disorders 2021 21:337
    Content type: Research Published on:

  30. Cardiovascular disease (CVD) is the leading cause of death among non-communicable diseases in South Africa. Several metabolic risk factors contribute to the development of CVD. Informal workers such as waste p...

    Authors: Felix Made, Engelbert A. Nonterah, Nonhlanhla Tlotleng, Vusi Ntlebi and Nisha Naicker
    Citation: BMC Cardiovascular Disorders 2021 21:336
    Content type: Research article Published on:

  31. Isolated splenic artery dissection (SAD) is extremely rare, life-threatening, and particularly difficult to diagnose. Moreover, SAD presenting as digestive hemorrhage has not been reported.

    Authors: Jianjun Jiang, Yang Liu and Xiangjiu Ding
    Citation: BMC Cardiovascular Disorders 2021 21:335
    Content type: Case report Published on:

  32. Previous studies have validated the capability of SYNTAX score (SS) and clinical SYNTAX score (CSS) in the prediction of clinical outcomes in patients who have undergone PCI; however, studies on comparison of ...

    Authors: Xiao-Qin Li, Chun Yin, Xiao-Li Li, Wen-Li Wu and Kun Cui
    Citation: BMC Cardiovascular Disorders 2021 21:334
    Content type: Research Published on:

  34. Recently, we face a surge in the fast-forward Coronavirus Disease 2019 (COVID-19) pandemic with nearly 170 million confirmed cases and almost 3.5 million confirmed deaths at the end of May 2021. Obesity, also ...

    Authors: Jacek Bil and Olga Możeńska
    Citation: BMC Cardiovascular Disorders 2021 21:332
    Content type: Commentary Published on:

  35. It is widely recognized that metabolic disorder is associated with pulmonary hypertension (PH). It is known that hypoxia-induced elevated pulmonary artery pressure in mice returns to normal pressure during reo...

    Authors: Koichi Sugimoto, Tetsuro Yokokawa, Tomofumi Misaka, Takashi Kaneshiro, Akiomi Yoshihisa, Kazuhiko Nakazato and Yasuchika Takeishi
    Citation: BMC Cardiovascular Disorders 2021 21:331
    Content type: Research Published on:

  37. Heart failure (HF) is a heterogeneous clinical syndrome and affects millions of people all over the world. HF occurs when the cardiac overload and injury, which is a worldwide complaint. The aim of this study ...

    Authors: Vijayakrishna Kolur, Basavaraj Vastrad, Chanabasayya Vastrad, Shivakumar Kotturshetti and Anandkumar Tengli
    Citation: BMC Cardiovascular Disorders 2021 21:329
    Content type: Research Published on:

  38. Little is known about the clinical value of Insulin-like growth factor-binding protein-7 (IGFBP7), a cellular senescence marker, in an elderly general population with multiple co-morbidities and high prevalenc...

    Authors: Jennifer M. T. A. Meessen, Giulia Cesaroni, Gian F. Mureddu, Alessandro Boccanelli, Ursula-Henrike Wienhues-Thelen, Peter Kastner, Luisa Ojeda-Fernandez, Deborah Novelli, Gianfranco Bazzoni, Maurizio Mangiavacchi, Nera Agabiti, Serge Masson, Lidia Staszewsky and Roberto Latini
    Citation: BMC Cardiovascular Disorders 2021 21:328
    Content type: Research article Published on:

  39. The relative association between cardiovascular (CV) risk factors, such as diabetes and hypertension, established CV disease (CVD), and susceptibility to CV complications or mortality in COVID-19 remains unclear.

    Authors: Kevin O’Gallagher, Anthony Shek, Daniel M. Bean, Rebecca Bendayan, Alexandros Papachristidis, James T. H. Teo, Richard J. B. Dobson, Ajay M. Shah and Rosita Zakeri
    Citation: BMC Cardiovascular Disorders 2021 21:327
    Content type: Research article Published on:

  40. Drug-coated balloons (DCBs) have shown superiority in the endovascular treatment of short femoropopliteal artery disease. Few studies have focused on outcomes in long lesions. This study aimed to evaluate the ...

    Authors: Xiaoxi Yu, Xin Zhang, Zhichao Lai, Jiang Shao, Rong Zeng, Wei Ye, Yuexin Chen, Bihui Zhang, Bo Ma, Wenteng Cao, Xiaolong Liu, Jinghui Yuan, Yuehong Zheng, Min Yang, Zhidong Ye and Bao Liu
    Citation: BMC Cardiovascular Disorders 2021 21:326
    Content type: Research Published on:

  41. This study was performed to investigate the clinical significance of combined evaluation of both coronary artery disease (CAD) and high-sensitivity cardiac troponin T (hs-cTnT) for prediction of major adverse ...

    Authors: Hang Liao, Huay Cheem Tan, Ziqiong Wang, Xiaoping Chen, Yong He and Sen He
    Citation: BMC Cardiovascular Disorders 2021 21:325
    Content type: Research article Published on:

  42. Treatment of heart failure with reduced ejection fraction (HFrEF) has been revolutionized by angiotensin receptor/neprilysin inhibitor (ARNI). ARNI has been shown to significantly reduce morbidity and mortalit...

    Authors: Wipharak Rattanavipanon, Thanyaluck Sotananusak, Fairus Yamaae, Arisa Chandrsawang, Pitchapa Kaewkan, Surakit Nathisuwan and Teerapat Yingchoncharoen
    Citation: BMC Cardiovascular Disorders 2021 21:324
    Content type: Research Published on:

  43. Self-expanding nitinol stent (SENS) implantation is commonly oversized in the superficial femoral artery (SFA), and leads to chronic outward force (COF) and in-stent restenosis (ISR). This study aimed to inves...

    Authors: Hu Li, Seung-Woon Rha, Byoung Geol Choi, Se Yeon Choi, Sang Ki Moon, Won Young Jang, Woohyeun Kim, Ji Hun Ahn, Sang-Ho Park, Woong Gil Choi, Rui Feng Yang, Wen Wei Bai, Cheol Ung Choi, Yang gi Ryu, Man Jong Baek and Dong Joo Oh
    Citation: BMC Cardiovascular Disorders 2021 21:323
    Content type: Research article Published on:

  44. The risk of cardiovascular diseases (CVDs) is becoming more prevalent in pregnant women though not much data is available for pregnant women with human immunodeficiency virus (HIV). Foetoplacental vascular end...

    Authors: Benedicta Ngwenchi Nkeh-Chungag, Godwill Azeh Engwa, Charles Businge, Mziwohlanga Mdondolo, Magdevy Pajaro Medina and Nandu Goswami
    Citation: BMC Cardiovascular Disorders 2021 21:322
    Content type: Study protocol Published on:

  45. Congenital heart disease (CHD) is the leading cause of mortality from birth defects. In adult CHD patients with successful surgical repair, cardiac complications including heart failure develop at late stage, ...

    Authors: Dongchen Fan, Shuchao Pang, Jing Chen, Jiping Shan, Qianjin Cheng and Bo Yan
    Citation: BMC Cardiovascular Disorders 2021 21:321
    Content type: Research article Published on:

  46. There appears to be an inequality in the risk of cardio-metabolic disease between those from a South Asian (SA) background when compared to those of White Europeans (WE) descendance, however, this association ...

    Authors: Munerah Almulhem, Joht Singh Chandan, Krishna Gokhale, Nicola J. Adderley, Rasiah Thayakaran, Kamlesh Khunti, Abd A. Tahrani, Wasim Hanif and Krishnarajah Nirantharakumar
    Citation: BMC Cardiovascular Disorders 2021 21:320
    Content type: Research article Published on:

  47. Since the early descriptions of large series of accessory atrioventricular pathway ablations in adults and adolescents over 20 years ago, there have been limited published reports based on more recent experien...

    Authors: Charlie Young, Annie Kwan, Lisa Yepez, Meghan McCarty, Amanda Chan, Dora Hsu, Jennifer Han, Taresh Taneja, Shirley Park, Robert Hayward and Taylor I. Liu
    Citation: BMC Cardiovascular Disorders 2021 21:319
    Content type: Research article Published on:

  48. Recent trials have revealed that sodium-glucose co-transporter 2 inhibitors (SGLT2-i) are effective against hyperglycemia and also reduce micro- and macro-vascular complications in patients with type 2 diabete...

    Authors: Sepehr Gohari, Tara Reshadmanesh, Hadi Khodabandehloo, Mojtaba Fathi, Hassan Ahangar, Shahram Arsang-Jang, Faramarz Ismail-Beigi, Samin Ghanbari, Mohsen Dadashi, Muhammad Javad Muhammadi, Sheida Gohari and Saeid Ghaffari
    Citation: BMC Cardiovascular Disorders 2021 21:318
    Content type: Study protocol Published on:

  49. Arterial calcification, the hallmark of arteriosclerosis, has a widespread distribution in the human body with only moderate correlation among sites. Hitherto, a single measure capturing the systemic burden of...

    Authors: Lieke M. Kuiper, M. Kamran Ikram, Maryam Kavousi, Meike W. Vernooij, M. Arfan Ikram and Daniel Bos
    Citation: BMC Cardiovascular Disorders 2021 21:317
    Content type: Research article Published on:

  50. There are relatively limited data regarding real-world outcomes in very old patients with three-vessel disease (3VD) receiving different therapeutic strategies. This study aimed to perform analysis of long-ter...

    Authors: Deshan Yuan, Sida Jia, Ce Zhang, Lin Jiang, Lianjun Xu, Yin Zhang, Jingjing Xu, Ru Liu, Bo Xu, Rutai Hui, Runlin Gao, Zhan Gao, Lei Song and Jinqing Yuan
    Citation: BMC Cardiovascular Disorders 2021 21:316
    Content type: Research article Published on:
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BMC Cardiovascular Disorders

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