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  1. Atherosclerosis is the main cause of carotid artery stenosis (CAS) which mostly occurs in the elderly. In this paper, the expression level of miR-375-3p in asymptomatic CAS patients and its diagnostic value fo...

    Authors: Yuxia Yin, Zhen Cheng, Xiaoling Fu and Shishun Ji

    Citation: BMC Cardiovascular Disorders 2021 21:518

    Content type: Research

    Published on:

  2. Adipsin has been identified as a secreted adipokine that plays a critical pathogenic role in metabolic disorders. However, it is not clear regarding the association of circulating adipsin with cardiovascular d...

    Authors: Jinhua Zhang, Fei Teng, Lingling Pan, Dan Guo, Jianfang Liu, Kangli Li, Youwen Yuan, Wenyuan Li and Huijie Zhang

    Citation: BMC Cardiovascular Disorders 2021 21:517

    Content type: Research

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  3. The non-invasive quantitative evaluation of left ventricle (LV) function plays a critical role in clinical cardiology. This study proposes a novel ultrasonic biomechanics method by integrating both LV vortex a...

    Authors: Aohua Zhang, Min Pan, Long Meng, Fengshu Zhang, Wei Zhou, Yaonan Zhang, Rongqin Zheng, Lili Niu and Yanling Zhang

    Citation: BMC Cardiovascular Disorders 2021 21:516

    Content type: Research article

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  4. Pacific people experience a disproportionate burden of cardiovascular disease (CVD), whether they remain in their country of origin or migrate to higher-income countries, such as Australia, Aotearoa New Zealan...

    Authors: Julie Winter-Smith, Vanessa Selak, Matire Harwood, Shanthi Ameratunga and Corina Grey

    Citation: BMC Cardiovascular Disorders 2021 21:515

    Content type: Research article

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  5. Pulmonary hypertension (PH) is a common complication of bronchopulmonary dysplasia (BPD) in very-low-birth-weight infants (VLBWIs). Although recent studies have increased awareness that PH contributes signific...

    Authors: Junfang Sun, Bowen Weng, Xiaoyue Zhang, Xiaoyun Chu and Cheng Cai

    Citation: BMC Cardiovascular Disorders 2021 21:514

    Content type: Research

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  6. Atherosclerosis is the leading cause of cardiovascular disease with a high mortality worldwide. Understanding the atherosclerosis pathogenesis and identification of efficient diagnostic signatures remain major...

    Authors: Feng Zhu, Lili Zuo, Rui Hu, Jin Wang, Zhihua Yang, Xin Qi and Limin Feng

    Citation: BMC Cardiovascular Disorders 2021 21:513

    Content type: Research

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  7. To investigate the midterm effect of exercise capacity and quality of life (QoL) of adult patients who underwent transthoracic device closure of ventricular septal defects (VSDs) and explore the gap in the qua...

    Authors: Qiang Chen, Rong Yang, Yu-Qing Lei, Kai-Peng Sun and Hua Cao

    Citation: BMC Cardiovascular Disorders 2021 21:512

    Content type: Research

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  8. The prognostic value of human epididymis protein 4 (HE4) in patients with ischemic cardiomyopathy (ICM) is unknown.

    Authors: Yi Tang, Yinzhen Wang, Xiaoping Xu, Laura Yan Tu, Pei Huang, Xiaoyan Yang, Lihua Li, Juan Wu, Yan Zhang, Qinghua Fu, Yingli Yu, Zhaofen Zheng, Lixia Song and Yi Zhang

    Citation: BMC Cardiovascular Disorders 2021 21:511

    Content type: Research

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  9. The mortality of metabolic-obesity phenotypes has been thoroughly studied, but it is not known if or how the association between mortality and body mass index (BMI), waist circumference or a body shape index (...

    Authors: Vilde Lehne Michalsen, Sarah H. Wild, Kirsti Kvaløy, Johan Svartberg, Marita Melhus and Ann Ragnhild Broderstad

    Citation: BMC Cardiovascular Disorders 2021 21:510

    Content type: Research article

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  10. To investigate the risk factors for mortality in patients with acute kidney injury requiring continuous renal replacement therapy (AKI-CRRT) after cardiac surgery.

    Authors: Chang Liu, Hai-Tao Zhang, Li-Jun Yue, Ze-Shi Li, Ke Pan, Zhong Chen, Su-Ping Gu, Tuo Pan, Jun Pan and Dong-Jin Wang

    Citation: BMC Cardiovascular Disorders 2021 21:509

    Content type: Research

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  11. Catheter ablation is an established therapy for atrial fibrillation (AF), but recurrence after ablation remains a great challenge. Additionally, little is known about the effect of renal function on the effici...

    Authors: Jing Zheng, Deling Zu, Keyun Cheng, Yunlong Xia, Yingxue Dong and Zhenyan Gao

    Citation: BMC Cardiovascular Disorders 2021 21:508

    Content type: Research

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  12. Atrial remodeling is the main developmental cause of atrial arrhythmias (AA), which may induce atrial fibrillation, atrial flutter, atrial tachycardia, and frequent premature atrial beats in acute myocardial i...

    Authors: Wenkai Liao, Li Xu, Yuxia Pan, Jie Wei, Peijia Wang, Xinchun Yang, Mulei Chen and Yuanfeng Gao

    Citation: BMC Cardiovascular Disorders 2021 21:507

    Content type: Research

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  13. Currently, the accepted effective method for assessing blood volume status, such as measuring central venous pressure (CVP) and mean pulmonary artery pressure (mPAP), is invasive. The purpose of this study was...

    Authors: Zhihang Ma, Jiaxin Gai, Yinghan Sun, Yunpeng Bai, Hongyi Cai, Lei Wu, Lixiu Sun, Junyan Liu, Li Xue and Bingchen Liu

    Citation: BMC Cardiovascular Disorders 2021 21:506

    Content type: Research

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  14. Relatively high rates of adherence to myocardial infarction (MI) secondary prevention medications have been reported, but register-based, objective real-world data is scarce. We aimed to analyse adherence to g...

    Authors: Piret Lõiveke, Toomas Marandi, Tiia Ainla, Krista Fischer and Jaan Eha

    Citation: BMC Cardiovascular Disorders 2021 21:505

    Content type: Research

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  15. In the present work, research was carried out to explore the correlation between the high-density lipoprotein cholesterol (HDL-C)/apolipoprotein A-I (apoA-I) ratio and serum free triiodothyronine (FT3) and the...

    Authors: Li Li, Gaojun Cai, Wei Lu, Feng Li, Lei Yu and Jianqiang Xiao

    Citation: BMC Cardiovascular Disorders 2021 21:504

    Content type: Research

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  16. Rheumatic heart disease (RHD) remains the leading cause of cardiac-related deaths and disability in children and young adults worldwide. In The Gambia, the RHD burden is thought to be high although no data are...

    Authors: Lamin E. S. Jaiteh, Lamin Drammeh, Suzanne T. Anderson, John Mendy, Samba Ceesay, Umberto D’Alessandro, Jonathan Carapetis, Mariana Mirabel and Annette Erhart

    Citation: BMC Cardiovascular Disorders 2021 21:503

    Content type: Research

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  17. Leadless pacemaker was a promising innovation than traditional transvenous pacemaker, the procedural complications were prone to be bleeding-related. However, very few reports also concerned about the thrombus...

    Authors: Qiang Chen, Yong Jiang Ma, Chun Hong Zhang and Li Wei Zhang

    Citation: BMC Cardiovascular Disorders 2021 21:502

    Content type: Case report

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  18. Despite numerous studies supporting the outperformance of ultrathin-strut bioresorbable polymer sirolimus-eluting stent (Orsiro SES, Biotronik AG), the generalizability of the study results remains unclear in ...

    Authors: Pannipa Suwannasom, Siriporn Athiksakul, Tasalak Thonghong, Vorarit Lertsuwunseri, Jarkarpun Chaipromprasit, Suphot Srimahachota, Wasan Udayachalerm, Srun Kuanprasert and Wacin Buddhari

    Citation: BMC Cardiovascular Disorders 2021 21:501

    Content type: Research

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  19. Renal denervation with radiofrequency ablation has become an accepted treatment for drug-resistant hypertension. However, there is a continuing need to develop new catheters for high-accuracy, targeted ablatio...

    Authors: Noel Pérez, Karl Muffly and Stephen E. Saddow

    Citation: BMC Cardiovascular Disorders 2021 21:500

    Content type: Research

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  20. Machine learning (ML) can include more diverse and more complex variables to construct models. This study aimed to develop models based on ML methods to predict the all-cause mortality in coronary artery disea...

    Authors: Xinyun Liu, Jicheng Jiang, Lili Wei, Wenlu Xing, Hailong Shang, Guangan Liu and Feng Liu

    Citation: BMC Cardiovascular Disorders 2021 21:499

    Content type: Research

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  21. Vascular endothelial dysfunction, arteriosclerosis and atherosclerotic plaque are well-known risk factors for cardiovascular disease (CVD). Studies on vascular health markers have been well-established, howeve...

    Authors: Huan Liu, Xiaohua Zhou, Jinbo Liu, Wei Huang, Na Zhao and Hongyu Wang

    Citation: BMC Cardiovascular Disorders 2021 21:498

    Content type: Study protocol

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  22. Complement activation has been associated with atherosclerosis, atherosclerotic plaque destabilization and increased risk of cardiovascular events. Complement component 7 (CC7) binds to the C5bC6 complex which...

    Authors: Reidun Aarsetøy, Thor Ueland, Pål Aukrust, Annika E. Michelsen, Ricardo Leon de la Fuente, Heidi Grundt, Harry Staines, Ottar Nygaard and Dennis W. T. Nilsen

    Citation: BMC Cardiovascular Disorders 2021 21:496

    Content type: Research

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  23. Arterial medial calcification (AMC) is associated with a high incidence of cardiovascular risk in patients with type 2 diabetes and chronic kidney disease. Here, we tested whether hydrogen sulfide (H2S) can preve...

    Authors: Fang-Zheng Wang, Hong Zhou, Hong-Yu Wang, Hang-Bing Dai, Qing Gao, Pei Qian and Ye-Bo Zhou

    Citation: BMC Cardiovascular Disorders 2021 21:495

    Content type: Research

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  24. Type 1 Brugada syndrome (BrS) is a hereditary arrhythmogenic disease showing peculiar electrocardiographic (ECG) patterns, characterized by ST-segment elevation in the right precordial leads, and risk of Sudde...

    Authors: M. A. Morales, M. Piacenti, M. Nesti, G. Solarino, P. Pieragnoli, G. Zucchelli, S. Del Ry, M. Cabiati and F. Vozzi

    Citation: BMC Cardiovascular Disorders 2021 21:494

    Content type: Study protocol

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  25. Non-Vitamin K antagonist oral anticoagulants (NOACs) emerged as an alternative with comparable or superior efficacy and safety to vitamin K antagonists (VKAs) for stroke prevention in patients with non-valvula...

    Authors: Arthur Shiyovich, Varda Shalev, Gabriel Chodick, Matanya Tirosh, Amos Katz, Miriam M. Klar, Mony Shuvy, David Pereg and Sa’ar Minha

    Citation: BMC Cardiovascular Disorders 2021 21:493

    Content type: Research article

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  26. In the Southern African countries, cardiovascular disease burden is increasing and the second most prevalent cause of death after infectious diseases. The sustainable primary prevention of cardiovascular disea...

    Authors: Mbuyiselo Douglas, Nancy Kgatla, Tholene Sodi, Geofrey Musinguzi, Tebogo Mothiba, Linda Skaal, Mpsanyana Makgahlela and Hilde Bastiaens

    Citation: BMC Cardiovascular Disorders 2021 21:492

    Content type: Research article

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  27. To provide multivariable prognostic models for severe complications prediction after heart valve surgery, including low cardiac output syndrome (LCOS), acute kidney injury requiring hemodialysis (AKI-rH) and m...

    Authors: Yunqi Liu, Jiefei Xiao, Xiaoying Duan, Xingwei Lu, Xin Gong, Jiantao Chen, Mai Xiong, Shengli Yin, Xiaobo Guo and Zhongkai Wu

    Citation: BMC Cardiovascular Disorders 2021 21:491

    Content type: Research

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  28. Several studies have recently addressed the importance of glycemic variability (GV) in patients with acute coronary syndrome (ACS). Although daily GV measures, such as mean amplitude of glycemic excursions, ar...

    Authors: Machiko Miyoshi, Hiroyasu Uzui, Tomohiro Shimizu, Takayoshi Aiki, Yuichiro Shiomi, Minoru Nodera, Hiroyuki Ikeda, Naoto Tama, Kanae Hasegawa, Tetsuji Morishita, Kentaro Ishida, Shinsuke Miyazaki and Hiroshi Tada

    Citation: BMC Cardiovascular Disorders 2021 21:490

    Content type: Research

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  29. We aimed to investigate the predictive value of recently updated ACEF II score on major adverse cardiac and cerebrovascular events (MACCE) in patients with multi-vessel coronary artery disease (MVCAD) undergoi...

    Authors: Yanyan Li, Chuang Li, Dejing Feng, Qian Zhang, Kuibao Li, Yu Liu, Xinchun Yang and Lefeng Wang

    Citation: BMC Cardiovascular Disorders 2021 21:489

    Content type: Research

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  30. Primary percutaneous coronary intervention is the treatment of choice in ST-segment elevation myocardial infarction and no-reflow phenomenon is still an unsolved problem.

    Authors: Ning Geng, Li Ren, Lisheng Xu, Deling Zou and Wenyue Pang

    Citation: BMC Cardiovascular Disorders 2021 21:488

    Content type: Research

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  31. Atrial fibrillation (AF) may cause cerebral and systemic embolism. An increased D-dimer level indicates hyperactivation of secondary fibrinolysis, resulting in predilection for thrombosis. To clarify the diffe...

    Authors: Tetsuya Watanabe, Koichi Tachibana, Yukinori Shinoda, Tomoko Minamisaka, Hidetada Fukuoka, Hirooki Inui, Keisuke Ueno, Souki Inoue, Kentaro Mine and Shiro Hoshida

    Citation: BMC Cardiovascular Disorders 2021 21:487

    Content type: Research article

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  32. Multi-parameter diagnostic devices can simplify cardiometabolic disease diagnosis. However, existing devices may not be suitable for use in low-resource settings, where the burden of non-communicable diseases ...

    Authors: Beatrice Vetter, David Beran, Philippa Boulle, Arlene Chua, Roberto de la Tour, Lucy Hattingh, Pablo Perel, Gojka Roglic, Rangarajan Sampath, Michael Woodman and Sigiriya Aebischer Perone

    Citation: BMC Cardiovascular Disorders 2021 21:486

    Content type: Research

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  33. Left ventricular hypertrophy is a pathophysiological response often due to chronic uncontrolled hypertension. Our primary aim was to investigate the magnitude, correlates and outcomes of left ventricular hyper...

    Authors: Sarah Shali Matuja, Patricia Munseri, Candida Moshiro, Khuzeima Khanbhai and Karim Mahawish

    Citation: BMC Cardiovascular Disorders 2021 21:485

    Content type: Research

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  34. The prevalence of coronary artery disease (CAD) continues to increase among young Chinese adults. Current smoking has been recognized as a major risk factor for premature CAD, and hyperhomocysteinaemia (HHcy) ...

    Authors: Jiayin Sun, Wei Han, Sijing Wu, Shuo Jia, Zhenxian Yan, Yonghe Guo, Yingxin Zhao, Yujie Zhou and Xiaoli Liu

    Citation: BMC Cardiovascular Disorders 2021 21:484

    Content type: Research

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  35. Early recurrences of atrial arrhythmias (ERAA) after atrial fibrillation (AF) catheter ablation do not predict procedural failure. A well-demarcated homogeneous lesion delivered by cryoballoon is less arrhythm...

    Authors: Karapet V. Davtyan, Arpi H. Topchyan, Hakob A. Brutyan, Elena N. Kalemberg, Maria S. Kharlap, Georgiy Yu. Simonyan, Andrey A. Kalemberg and Maria V. Kuznetsova

    Citation: BMC Cardiovascular Disorders 2021 21:483

    Content type: Research

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  36. Growing evidence indicates that poor sleep harms health. Early to bed and early to rise is considered as a healthy lifestyle in Chinese population. The current study aimed to examine the effects of sleep habit...

    Authors: Xiaoqing Lian, Jie Gu, Sibo Wang, Jianjun Yan, Xiaowen Chen, Mingwei Wang, Yuqing Zhang and Liansheng Wang

    Citation: BMC Cardiovascular Disorders 2021 21:481

    Content type: Research article

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  37. Timely acquisition of 12-lead Electrocardiogram (ECG) in the emergency department (ED) is crucial and recommended by current guidelines.

    Authors: Lukas Andreas Heger, Tina Glück, Klaus Kaier, Marcus Hortmann, Marina Rieder, Patrick M. Siegel, Philipp Diehl, Tobias Wengenmayer, Christoph B. Olivier, Christoph Bode, Hans-Joerg Busch, Daniel Duerschmied and Ingo Ahrens

    Citation: BMC Cardiovascular Disorders 2021 21:480

    Content type: Research

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  38. Stable coronary artery disease (CAD) patients with myocardial damage have a poor prognosis compared to those without myocardial damage. Recently, malnutrition has been reported to affect the prognosis of cardi...

    Authors: Ryo Arikawa, Daisuke Kanda, Yoshiyuki Ikeda, Akihiro Tokushige, Takeshi Sonoda, Kazuhiro Anzaki and Mitsuru Ohishi

    Citation: BMC Cardiovascular Disorders 2021 21:479

    Content type: Research

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  39. Heart failure is a common and chronic heart condition with high prevalence and mortality rates. This debilitating disease as an important predictor of health outcomes is directly related to patients' quality o...

    Authors: Hossein Habibzadeh, Akram Shariati, Farshad Mohammadi and Salman Babayi

    Citation: BMC Cardiovascular Disorders 2021 21:478

    Content type: Research

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  40. Coronary artery disease (CAD) is a universal public health challenge, more prominently so in the low- and middle-income countries. In this study, we aimed to determine prevalence and trends of CAD risk factors...

    Authors: Kaveh Hosseini, Seyedeh Hamideh Mortazavi, Saeed Sadeghian, Aryan Ayati, Mahdi Nalini, Arya Aminorroaya, Hamed Tavolinejad, Mojtaba Salarifar, Hamidreza Pourhosseini, Afsaneh Aein, Arash Jalali, Ali Bozorgi, Mehdi Mehrani and Farin Kamangar

    Citation: BMC Cardiovascular Disorders 2021 21:477

    Content type: Research

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  41. The study sought to compare Coronary Artery Disease Reporting and Data System (CAD-RADS) classification with traditional coronary artery disease (CAD) classifications and Duke Prognostic CAD Index for predicti...

    Authors: Zengfa Huang, Shutong Zhang, Nan Jin, Yun Hu, Jianwei Xiao, Zuoqin Li, Yang Yang, Ruihong Sun, Zheng Wang, Xiang Li, Yuanliang Xie and Xiang Wang

    Citation: BMC Cardiovascular Disorders 2021 21:476

    Content type: Research

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  42. HSCR, a colonic neurocristopathy affecting 1/5000 births, is suggested to associate with cardiac septal defects and conotruncal malformations. However, we question subtle cardiac changes maybe more commonly pr...

    Authors: Ko-Chin Chen, Ko-Chien Chen, Zan-Min Song and Geoffrey D. Croaker

    Citation: BMC Cardiovascular Disorders 2021 21:475

    Content type: Research article

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  43. Recent evidence has shown that the pathogenesis of ischaemic stroke associated with atrial fibrillation (AF) is complex and involves other factors in addition to arrhythmias. The purpose of this study was to i...

    Authors: Boqun Shi, Demin Liu, Qian Wang, Xue Geng, Qian Hou, Guoqiang Gu, Ruiqin Xie and Wei Cui

    Citation: BMC Cardiovascular Disorders 2021 21:474

    Content type: Research article

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  44. Trimetazidine (TMZ) pretreatment protects cardiomyocytes during cardiac surgery. TMZ may protect elderly patients with ischaemic heart disease (IHD) undergoing non-cardiac surgery.

    Authors: Zhong-Liang Dai, Yi-Feng Song, Ya Tian, Yin Li, Miao Lin, Juan Lin, Qi Wang, Ping Wang and Wen-Li Gao

    Citation: BMC Cardiovascular Disorders 2021 21:473

    Content type: Research

    Published on:

  45. High blood pressure is a well-recognized risk factor for cardiovascular events, and the incidence of hypertension is increasing among young people. This study investigated the relationship between ALT and AST ...

    Authors: Lijun Zhu, Zhengmei Fang, Yuelong Jin, Weiwei Chang, Mengyun Huang, Lianping He, Yan Chen and Yingshui Yao

    Citation: BMC Cardiovascular Disorders 2021 21:472

    Content type: Research

    Published on:

  46. The association between anxiety and atrial fibrillation (AF) remains unclear. Moreover, this association has rarely been studied in Chinese individuals aged 60 years or older. This study investigated the assoc...

    Authors: Zhu-Xia Shen, Yu-Min Sun, Hui-Hui Gu, Yan Zhang, Zhi-Wen Shen, Xiao-Niu Liang, Ding Ding and Jun Wang

    Citation: BMC Cardiovascular Disorders 2021 21:471

    Content type: Research

    Published on:

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