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  1. Rheumatic heart disease (RHD) is the most common acquired heart disease occurring in children and adolescents. RHD is associated with significant morbidity and mortality particularly in low and middle- income ...

    Authors: Parvina Titus Kazahura, Theophylly L. Mushi, Pedro Pallangyo, Mohamed Janabi, Rodrick Kisenge, Mazen Albaghdadi, Naizihijwa Majani and Edward Kija
    Citation: BMC Cardiovascular Disorders 2021 21:610
  2. Although the pathophysiology of coronary slow flow (CSF) has not been fully elucidated, emerging data increasingly support potential role for subclinical diffuse atherosclerosis in the etiology of CSF. We aime...

    Authors: Abdulmecit Afsin, Hakan Kaya, Arif Suner, Kader Eliz Uzel, Nurbanu Bursa, Yusuf Hosoglu, Fethi Yavuz and Ramazan Asoglu
    Citation: BMC Cardiovascular Disorders 2021 21:608
  3. Despite several therapies, pulmonary hypertension (PH) is still a severe disease which can lead to right heart failure. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are ...

    Authors: Adriana Marc, Calin Pop, Adela-Viviana Sitar-Taut, Liviuta Budisan, Ioana Berindan-Neagoe and Dana Pop
    Citation: BMC Cardiovascular Disorders 2021 21:607
  4. Ventricular septal rupture (VSR) is a rare but severe complication of acute myocardial infarction (AMI). For such cases, surgical repair is recommended by major guidelines, but not always possible for such cases.

    Authors: Chuan Yang, Yong Sun, Deling Zou, Zhaoqing Sun, Xinzhong Zhang, Guangsheng Su, Jing Qi and Wenyue Pang
    Citation: BMC Cardiovascular Disorders 2021 21:605
  5. Histidine-tryptophan-ketoglutarate (HTK) and del Nido (DN) cardioplegia are intracellular-type and extracellular-type solution respectively, both can provide a long period of myocardial protection with single-...

    Authors: Lian Duan, Guo-huang Hu, E. Wang, Cheng-liang Zhang, Ling-jin Huang and Yan-ying Duan
    Citation: BMC Cardiovascular Disorders 2021 21:604
  6. Exposure to glyoxal, the smallest dialdehyde, is associated with several diseases; humans are routinely exposed to glyoxal because of its ubiquitous presence in foods and the environment. The aim of this study...

    Authors: Ming-Zhang Xie, Chun Guo, Jia-Qi Dong, Jie Zhang, Ke-Tao Sun, Guang-Jian Lu, Lei Wang, De-Ying Bo, Lu-Yang Jiao and Guo-An Zhao
    Citation: BMC Cardiovascular Disorders 2021 21:603
  7. Obesity is a risk factor for several cardiovascular diseases (CVDs), including atrial fibrillation (AF). However, it is less clear whether overall fat or abdominal fat distribution are most important for risk ...

    Authors: Isac Zia, Linda Johnson, Ensieh Memarian, Yan Borné and Gunnar Engström
    Citation: BMC Cardiovascular Disorders 2021 21:602
  8. Growth differentiation factor (GDF)-15 is linked to inflammation, cancer, and atherosclerosis. GDF-15 is expressed in most tissues but is extremely induced under pathological conditions. Elevated serum levels ...

    Authors: G. A. Bonaterra, N. Struck, S. Zuegel, A. Schwarz, L. Mey, H. Schwarzbach, J. Strelau and R. Kinscherf
    Citation: BMC Cardiovascular Disorders 2021 21:601
  9. Despite established guidelines on secondary prevention of cardiovascular disease, practical implementation of treatment targets is deficient even in high-income countries. This study compared long-term hospita...

    Authors: Anete Kaldal, Serena Tonstad and Jarle Jortveit
    Citation: BMC Cardiovascular Disorders 2021 21:600
  10. To investigate the frequencies and patterns of cardiovascular diseases (CVDs), including rheumatic and congenital heart diseases, among patients with abnormal hearts assessed by echocardiographic examination.

    Authors: Gökhan Alıcı and Ömer Genç
    Citation: BMC Cardiovascular Disorders 2021 21:599
  11. Women with atrial fibrillation (AF) experience greater symptomatology, worse quality of life, and have a higher risk of stroke as compared to men, but are less likely to receive rhythm control treatment. Wheth...

    Authors: Vinita Subramanya, J’Neka S. Claxton, Pamela L. Lutsey, Richard F. MacLehose, Lin Y. Chen, Alanna M. Chamberlain, Faye L. Norby and Alvaro Alonso
    Citation: BMC Cardiovascular Disorders 2021 21:598
  12. The association between the presence of a diagonal earlobe crease (DEC) and coronary artery disease has been prescribed earlier. However, it is unclear whether patients with acute myocardial infarction (AMI) a...

    Authors: Christian Thilo, Christine Meisinger, Margit Heier, Wolfgang von Scheidt and Inge Kirchberger
    Citation: BMC Cardiovascular Disorders 2021 21:597
  13. To compare clinical and psychological factors among patients with self-perceived statin-associated muscle symptoms (SAMS), confirmed SAMS, and refuted SAMS in coronary heart disease patients (CHD).

    Authors: Kari Peersen, John Munkhaugen, Elise Sverre, Oscar Kristiansen, Morten Fagerland, Nils Tore Vethe, Joep Perk, Einar Husebye and Toril Dammen
    Citation: BMC Cardiovascular Disorders 2021 21:596
  14. The health belief model is one of the applicable methods of training health preventive behaviors, especially in patients with cardiovascular diseases. Therefore, this study aimed to determine the effect of pat...

    Authors: Hossein Habibzadeh, Aynaz Bagherzadi, Alireza Didarloo and Hamidreza Khalkhali
    Citation: BMC Cardiovascular Disorders 2021 21:595
  15. Coarctation of the Aorta (CoA) is a relatively common cardiovascular disorder. The present study aimed to evaluate the effect of COA anatomy and high versus low-pressure balloons on the outcome of balloon angi...

    Authors: Hamid Amoozgar, Narjes Nouri, Sajad Shabanpourhaghighi, Neda Bagherian, Nima Mehdizadegan, Mohammad Reza Edraki, Amir Naghshzan, Hamid Mohammadi, Gholamhossein Ajami and Ashkan Abdollahi
    Citation: BMC Cardiovascular Disorders 2021 21:594
  16. The extent to which the risk of atherosclerotic cardiovascular disease (ACVD) is increased among people living with HIV (PLWH) in sub-Saharan Africa remains unknown.

    Authors: Prossy Bibangambah, Linda C. Hemphill, Moses Acan, Alexander C. Tsai, Ruth N. Sentongo, June-Ho Kim, Isabelle T. Yang, Mark J. Siedner and Samson Okello
    Citation: BMC Cardiovascular Disorders 2021 21:593
  17. COVID-19 and Fontan physiology have each been associated with an elevated risk of venous thromboembolism (VTE), however little is known about the risks and potential consequences of having both.

    Authors: Neema Jamshidi, Weiyi Tan, Dingle Foote, Leigh Reardon, Gentian Lluri, Jamil Aboulhosn, John Moriarty and Jeannette Lin
    Citation: BMC Cardiovascular Disorders 2021 21:592
  18. SYNTAX score (SS) was shown to positively correlate with postprocedural myocardial injury in patients after elective coronary artery intervention, but evidence about the association of SS with myocardial salva...

    Authors: Guangren Gao, Lianrong Feng, Jinguo Fu, Yi Li, Zhaoyang Huo, Lei Zhang, Lei Wang, Heping Niu, Liqing Kang and Jun Zhang
    Citation: BMC Cardiovascular Disorders 2021 21:591
  19. Optimal projection is essential for valve deployment during transcatheter aortic valve implantation (TAVI). The purpose of this study was to propose an approach to predict optimal projection in TAVI candidates...

    Authors: Xi Wang, Fei Chen, Tian-Yuan Xiong, Yi-Jian Li, Yuan-Weixiang Ou, Qiao Li, Yong Peng, Jia-Fu Wei, Sen He, Mao Chen and Yuan Feng
    Citation: BMC Cardiovascular Disorders 2021 21:590
  20. Nutritional factors have been identified as preventable risk factors for cardiovascular disease; this study aimed to investigate the application of the Theory of Planned Behavior (TPB) in nutritional behaviors...

    Authors: Ali Khani Jeihooni, Hanieh Jormand, Negin Saadat, Mahmood Hatami, Rosliza Abdul Manaf and Pooyan Afzali Harsini
    Citation: BMC Cardiovascular Disorders 2021 21:589
  21. Although the levels of plasma fibrinogen and albumin have been proven to be in relation to coronary heart disease (CHD), the association between fibrinogen-to-albumin ratio (FAR) and acute coronary syndrome (A...

    Authors: Zhenzhen Duan, Chaodi Luo, Bowen Fu and Dan Han
    Citation: BMC Cardiovascular Disorders 2021 21:588
  22. In patients with atrial fibrillation (AF) and functional mitral regurgitation (MR), catheter ablation reduces the severity of MR and improves cardiac remodeling. However, its effects on prognosis are uncertain.

    Authors: Jin-Tao Wu, Dan-Qing Zhao, Fu-Tao Zhang, Xiao-Jie Liu, Juan Hu, Lei-Ming Zhang, Xian-Wei Fan, Hai-Tao Yang, Li-Jie Yan, Jing-Jing Liu and Shan-Ling Wang
    Citation: BMC Cardiovascular Disorders 2021 21:587
  23. Epidemiological studies have repeatedly observed a markedly higher risk for coronary artery disease (CAD) in Scotland as compared to England. Up to now, it is unclear whether environmental or genetic factors m...

    Authors: Chuhua Yang, Fabian Starnecker, Shichao Pang, Zhifen Chen, Ulrich Güldener, Ling Li, Matthias Heinig and Heribert Schunkert
    Citation: BMC Cardiovascular Disorders 2021 21:586
  24. Cardiovascular Diseases (CVDs) are the first leading cause of death worldwide. The present study aimed to investigate the relationship between demographics, anthropometrics, sleep duration, physical activity, ...

    Authors: Alireza Mirahmadizadeh, Mojtaba Farjam, Mehdi Sharafi, Hossein Fatemian, Maryam Kazemi, Kiarash Roustai Geraylow, Azizallah Dehghan, Zahra Amiri and Sima Afrashteh
    Citation: BMC Cardiovascular Disorders 2021 21:585
  25. There are less studies focusing on the sedative therapy of acute myocardial infarction (AMI) critical patients. This study aim to compare the impact on the prognosis of AMI critical patients of using midazolam...

    Authors: Xiaowei Jiang and Min Yan
    Citation: BMC Cardiovascular Disorders 2021 21:584
  26. Cardiovascular disease in particular acute coronary syndrome (ACS) is remained one of the most cause of morbidity and mortality, annually. Considering inflammatory pathway of atherosclerosis, colchicine as an ...

    Authors: Mehdi Akrami, Peyman Izadpanah, Mehdi Bazrafshan, Unes Hatamipour, Navid Nouraein, Hamed Bazrafshan Drissi and Alireza Manafi
    Citation: BMC Cardiovascular Disorders 2021 21:583
  27. To estimate the association between the aggregation and pair-wise combination of selected cardiovascular risk factors (CVRF) and 10-year all-cause mortality.

    Authors: Janina Bazalar-Palacios, J. Jaime Miranda, Rodrigo M. Carrillo-Larco, Robert H. Gilman, Liam Smeeth and Antonio Bernabe-Ortiz
    Citation: BMC Cardiovascular Disorders 2021 21:582
  28. High-Frequency Irreversible Electroporation (H-FIRE) is a novel technology for non-thermal ablation. Different from Irreversible electroporation (IRE), H-FIRE delivers bipolar electrical pulses without muscle ...

    Authors: Jing Li, Jingjing Wang, Xiaobo Zhang, Xiao Zhang, Hongmei Gao and Yueyong Xiao
    Citation: BMC Cardiovascular Disorders 2021 21:581
  29. Conventional cardiac magnetic resonance (CCMR) imaging is usually performed with breath-holding (BH), which is adverse in patients with BH limitations. We explored the ability of a free-breathing CMR (fCMR) pr...

    Authors: Keyan Wang, Wenbo Zhang, Shuman Li, Xiaoming Bi, Michaela Schmidt, Jing An, Jie Zheng and Jingliang Cheng
    Citation: BMC Cardiovascular Disorders 2021 21:580
  30. It was recently shown that new-onset diabetes patients without previous cardiovascular disease have experienced a markedly reduced risk of adverse cardiovascular events from 1996 to 2011. However, it remains u...

    Authors: Esben Skov Jensen, Kevin Kris Warnakula Olesen, Christine Gyldenkerne, Pernille Gro Thrane, Lisette Okkels Jensen, Bent Raungaard, Per Løgstrup Poulsen, Reimar Wernich Thomsen and Michael Maeng
    Citation: BMC Cardiovascular Disorders 2021 21:579
  31. The present investigation was developed for the exploration of the association between IL-6 levels and acute coronary syndrome (ACS) findings upon angiographic evaluation.

    Authors: Yang Ling, Hairong Weng and Shengxing Tang
    Citation: BMC Cardiovascular Disorders 2021 21:578
  32. The pathogenic mechanisms of venous thromboembolism (VT) remain to be defined. This study aimed to identify differentially expressed genes (DEGs) that could serve as potential therapeutic targets for VT.

    Authors: Guoju Fan, Zhihai Jin, Kaiqiang Wang, Huitang Yang, Jun Wang, Yankui Li, Bo Chen and Hongwei Zhang
    Citation: BMC Cardiovascular Disorders 2021 21:577
  33. Increased waist circumference (WC) is one of the cardiovascular disease (CVD) risk factors used to predict cardiovascular events. Waist circumference cut-off values for predicting metabolic syndrome and other ...

    Authors: M. C. Ringane and S. S. R. Choma
    Citation: BMC Cardiovascular Disorders 2021 21:575
  34. We performed a meta-analysis sought to investigate the risk of stroke with antiplatelet and anticoagulant therapies among patients with coronary artery disease (CAD).

    Authors: Qiao Yu Shao, Zhi Jian Wang, Xiao Teng Ma, Xu Ze Lin, Liu Pan and Yu Jie Zhou
    Citation: BMC Cardiovascular Disorders 2021 21:574
  35. The relationship between obesity indices and arterial stiffness (AS) has not been fully discovered nor has it been studied in depth in large hypertensive patient populations. The aim of this study was to explo...

    Authors: Feng Hu, Rihua Yu, Fengyu Han, Juan Li, Wei Zhou, Tao Wang, Lingjuan Zhu, Xiao Huang, Huihui Bao and Xiaoshu Cheng
    Citation: BMC Cardiovascular Disorders 2021 21:573
  36. Data on the relationship of baseline serum uric acid (SUA) with development of low-density lipoprotein cholesterol (LDL-C) level in patients with first acute myocardial infarction (AMI) are limited. The presen...

    Authors: Yang Chen, Congcong Ding, Longlong Hu, Yuehua Ruan, Kai Zou, Cong Dai, Yanhui Liao, Hanhui Liao, Yi Xia, Yuanbin Zhao and Renqiang Yang
    Citation: BMC Cardiovascular Disorders 2021 21:572
  37. We sought to describe the tendency and extent of high-sensitivity cardiac troponin I (hs-cTnI) changes in patients with fulminant myocarditis (FM) after admission and to explore the relationship between the in...

    Authors: Chao Liu, Zhongqin Wang, Kengquan Chen, Guanglin Cui, Chen Chen, Luyun Wang and Jiangang Jiang
    Citation: BMC Cardiovascular Disorders 2021 21:571
  38. Irisin is a novel myokine associated with obesity, which is a traditional cardiovascular risk factor (CVRF). The present study aimed to investigate the association between serum irisin and a single CVRF as wel...

    Authors: Ruoyi Liu, Qiao Zhang, Nianchun Peng, Shujing Xu, Miao Zhang, Ying Hu, Zhengyi Chen, Kun Tang, Xi He, Yi Li and Lixin Shi
    Citation: BMC Cardiovascular Disorders 2021 21:570
  39. The platelet-lymphocyte ratio (PLR), a novel inflammatory marker, is generally associated with increased in-hospital mortality risk. We aimed to investigate the association between PLR and postoperative in-hos...

    Authors: Xi Xie, Xiangjie Fu, Yawen Zhang, Wanting Huang, Lingjin Huang, Ying Deng, Danyang Yan, Run Yao and Ning Li
    Citation: BMC Cardiovascular Disorders 2021 21:569
  40. The aim of the study was to analyze the impact of concomitant coronary artery disease (CAD) assessed by the SYNTAX score (SS) and periprocedural percutaneous coronary intervention (PCI) on outcomes after trans...

    Authors: Tilman Stephan, Eva Thoma, Manuel Rattka, Dominik Felbel, Dominik Buckert, Wolfgang Rottbauer, Birgid Gonska and Sinisa Markovic
    Citation: BMC Cardiovascular Disorders 2021 21:568
  41. Coronary artery fistula refers to an abnormal communication between a coronary artery and great vessel, a cardiac chamber or other structure. The left circumflex artery (LCX) pericardia fistula combined with h...

    Authors: Zhiyan Shen, Kun Xia, Xinfeng Liu and Rongpin Wang
    Citation: BMC Cardiovascular Disorders 2021 21:567
  42. Recent studies have focused on the potential role of epicardial adipose tissue (EAT) in the development of coronary artery disease (CAD). ABCA1 and ABCG1 transporters regulate cell cholesterol content and reve...

    Authors: Valentina V. Miroshnikova, Alexandra A. Panteleeva, Irina A. Pobozheva, Natalia D. Razgildina, Ekaterina A. Polyakova, Anton V. Markov, Olga D. Belyaeva, Olga A. Berkovich, Elena I. Baranova, Maria S. Nazarenko, Valery P. Puzyrev and Sofya N. Pchelina
    Citation: BMC Cardiovascular Disorders 2021 21:566
  43. The diagnosis of malignant pericardial effusion (MPE) is often associated with a poor prognosis, but due to the complexity and unspecific nature of MPE patients' clinical manifestations, imaging often performs...

    Authors: Shucai Wang, Jiazheng Zhao, Chanchan Wang and Ning Zhang
    Citation: BMC Cardiovascular Disorders 2021 21:565
  44. Although various studies have been conducted on the effects of seasonal climate changes or emotional variables on the risk of AMI, many of them have limitations to determine the predictable model. The currents...

    Authors: Hamid Sharif Nia, Ozkan Gorgulu, Navaz Naghavi, Erika Sivarajan Froelicher, Fatemeh Khoshnavay Fomani, Amir Hossein Goudarzian, Saeed Pahlevan Sharif, Roghiyeh Pourkia and Ali Akbar Haghdoost
    Citation: BMC Cardiovascular Disorders 2021 21:563

    The Correction to this article has been published in BMC Cardiovascular Disorders 2022 22:243

  45. Aberrant right subclavian artery (ARSA) with associated Kommerell diverticulum (KD) is a rare congenital aortic disease. KD patients have a high risk of rupture, dissection, and compression of adjacent structu...

    Authors: Tieyan Li, Lin Zou, Yunzhen Feng, Guoliang Fan and Yuanfeng Xin
    Citation: BMC Cardiovascular Disorders 2021 21:562
  46. Constrictive pericarditis (CP) is characterized by scarring and loss of elasticity of the pericardium. This case demonstrates that mixed martial arts (MMA) is a previously unrecognized risk factor for CP, diag...

    Authors: Meganne N. Ferrel, Sentia Iriana, I. Raymond Thomason, Christy L. Ma, Katsiaryna Tsarova, Brent D. Wilson, Stephen H. McKellar and John J. Ryan
    Citation: BMC Cardiovascular Disorders 2021 21:561
  47. Takayasu arteritis is a chronic inflammatory disease involving the aorta and its major branches. Acute myocardial infarction rarely but not so much presents in patients with Takayasu arteritis, and the prefera...

    Authors: Shiqiang Zhou, Chao Gao and Fei Li
    Citation: BMC Cardiovascular Disorders 2021 21:560

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