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  1. Studies have suggested that the prevention and treatment of coronary heart disease may not have been as effective in women as in men. Therefore, we aimed to examine whether the incidence, attack rate and morta...

    Authors: Hanna-Riikka Lehto, Seppo Lehto, Aki S Havulinna, Matti Ketonen, Aapo Lehtonen, Y Antero Kesäniemi, Juhani Airaksinen and Veikko Salomaa
    Citation: BMC Cardiovascular Disorders 2007 7:35
  2. Little is known about the impact of severity of hypertension on the association of genes with high blood pressure, which may cause the inconsistently reported associations of peroxisome proliferator-activated ...

    Authors: Gaoqiang Xie, Dongshuang Guo, Ying Li, Shengying Liang and Yangfeng Wu
    Citation: BMC Cardiovascular Disorders 2007 7:33
  3. Coronary artery disease (CAD) is a leading cause of mortality, morbidity, and disability with high health care cost in Iran. It accounts for nearly 50 percent of all deaths per year. Yet little is known about ...

    Authors: ZN Hatmi, S Tahvildari, A Gafarzadeh Motlag and A Sabouri Kashani
    Citation: BMC Cardiovascular Disorders 2007 7:32
  4. Serum aminotransferase concentrations are reportedly strongly associated with insulin resistance, an established cardiovascular risk factor that is not routinely assessed in clinical practice. We therefore exp...

    Authors: Patrick H Dessein, Angela J Woodiwiss, Barry I Joffe and Gavin R Norton
    Citation: BMC Cardiovascular Disorders 2007 7:31
  5. Data accumulated from mouse studies and in vitro studies of human arteries support the notion that soluble intercellular adhesion molecule-1 (sICAM-1) and monocyte chemoattractant protein-1 (MCP-1) play import...

    Authors: Weihong Tang, James S Pankow, J Jeffrey Carr, Russell P Tracy, Suzette J Bielinski, Kari E North, Paul N Hopkins, Aldi T Kraja and Donna K Arnett
    Citation: BMC Cardiovascular Disorders 2007 7:30
  6. The study was designed to investigate the effect of different measuring methodologies on the estimation of P wave duration. The recording length required to ensure reproducibility in unfiltered, signal-average...

    Authors: Fredrik Holmqvist, Pyotr G Platonov, Rasmus Havmöller and Jonas Carlson
    Citation: BMC Cardiovascular Disorders 2007 7:29
  7. Unstable angina (UA) patients have lower mortality and reinfarction risks than ST-elevation (STEMI) or non-ST elevation myocardial infarction (NSTEMI) patients and, accordingly, receive less aggressive treatme...

    Authors: Thomas M Maddox, Kimberly J Reid, John S Rumsfeld and John A Spertus
    Citation: BMC Cardiovascular Disorders 2007 7:28
  8. Cardiovascular diseases (CVD) are the leading cause of death and the third cause of disability in Europe. Prevention programmes should include interventions aimed at a reduction of medical risk factors (hypert...

    Authors: Neree Claes and Nele Jacobs
    Citation: BMC Cardiovascular Disorders 2007 7:27
  9. Cardiac arrest survivors may experience hypoxic brain injury that results in cognitive impairments which frequently remain unrecognised. This may lead to limitations in daily activities and participation in so...

    Authors: Véronique RMP Moulaert, Jeanine A Verbunt, Caroline M van Heugten, Wilbert GM Bakx, Anton PM Gorgels, Sebastiaan CAM Bekkers, Marc CFTM de Krom and Derick T Wade
    Citation: BMC Cardiovascular Disorders 2007 7:26
  10. Chronic congestive heart failure (CHF) is a complex disease with rising prevalence, compromised quality of life (QoL), unplanned hospital admissions, high mortality and therefore high burden of illness. The de...

    Authors: Frank Peters-Klimm, Thomas Müller-Tasch, Dieter Schellberg, Jochen Gensichen, Christiane Muth, Wolfgang Herzog and Joachim Szecsenyi
    Citation: BMC Cardiovascular Disorders 2007 7:25
  11. Studies have shown patients who are delayed for surgical cardiac revascularization are faced with increased risks of symptom deterioration and death. This could explain the observation that operative mortality...

    Authors: Adrian R Levy, Boris G Sobolev, Lisa Kuramoto, Robert Hayden and Stuart M MacLeod
    Citation: BMC Cardiovascular Disorders 2007 7:24
  12. Diagnosing heart failure and left ventricular systolic dysfunction is difficult on clinical grounds alone. We sought to determine the accuracy of a heart failure register in a single primary care practice, and...

    Authors: Gurbir S Bhatia, Michael D Sosin, Jane Stubley, Jeetesh V Patel, Elizabeth A Hughes, Rebecca Gibbs and Russell C Davis
    Citation: BMC Cardiovascular Disorders 2007 7:23
  13. We have previously documented significant differences in orthogonal P wave morphology between patients with and without paroxysmal atrial fibrillation (PAF). However, there exists little data concerning normal...

    Authors: Rasmus Havmoller, Jonas Carlson, Fredrik Holmqvist, Alberto Herreros, Carl J Meurling, Bertil Olsson and Pyotr Platonov
    Citation: BMC Cardiovascular Disorders 2007 7:22
  14. Post thrombotic syndrome (PTS) is a burdensome and costly complication of deep venous thrombosis (DVT) that develops in 20–40% of patients within 1–2 years after symptomatic DVT. Affected patients have chronic...

    Authors: Susan R Kahn, Hadia Shbaklo, Stan Shapiro, Philip S Wells, Michael J Kovacs, Marc A Rodger, David R Anderson, Jeffrey S Ginsberg, Mira Johri and Vicky Tagalakis
    Citation: BMC Cardiovascular Disorders 2007 7:21
  15. Low dietary intake of the essential nutrient choline and its metabolite betaine may increase atherogenesis both through effects on homocysteine methylation pathways as well as through choline's antioxidants pr...

    Authors: Aurelian Bidulescu, Lloyd E Chambless, Anna Maria Siega-Riz, Steven H Zeisel and Gerardo Heiss
    Citation: BMC Cardiovascular Disorders 2007 7:20
  16. Asymptomatic subjects at intermediate coronary risk may need diagnostic testing for risk stratification. Both measurement of coronary calcium scores and exercise testing are well established tests for this pur...

    Authors: Christiane A Geluk, Riksta Dikkers, Jan A Kors, René A Tio, Riemer HJA Slart, Rozemarijn Vliegenthart, Hans L Hillege, Tineke P Willems, Paul E de Jong, Wiek H van Gilst, Matthijs Oudkerk and Felix Zijlstra
    Citation: BMC Cardiovascular Disorders 2007 7:19
  17. Electrical neurostimulation can be used to treat patients with refractory angina, it reduces angina and ischemia. Previous data have suggested that electrical neurostimulation may alleviate myocardial ischaemi...

    Authors: Jessica de Vries, Rutger L Anthonio, Mike JL DeJongste, Gillian A Jessurun, Eng-Shiong Tan, Bart JGL de Smet, Ad FM van den Heuvel, Michiel J Staal and Felix Zijlstra
    Citation: BMC Cardiovascular Disorders 2007 7:18
  18. We aimed to assess whether we could identify a graded association between increasing number of components of the metabolic syndrome and cardiac structural and functional abnormalities independently of predicte...

    Authors: Ana Azevedo, Paulo Bettencourt, Pedro B Almeida, Ana C Santos, Cassiano Abreu-Lima, Hans-Werner Hense and Henrique Barros
    Citation: BMC Cardiovascular Disorders 2007 7:17
  19. Cardiac asthma is common, but has been poorly investigated. The objective was to compare the characteristics and outcome of cardiac asthma with that of classical congestive heart failure (CHF) in elderly patie...

    Authors: Stéphane Jorge, Marie-Hélène Becquemin, Samuel Delerme, Mohamed Bennaceur, Richard Isnard, Rony Achkar, Bruno Riou, Jacques Boddaert and Patrick Ray
    Citation: BMC Cardiovascular Disorders 2007 7:16
  20. Sirolimus (SRL, Rapamycin) has been used successfully to inhibit restenosis both in drug eluting stents (DES) and after systemic application. The current study reports on the effects of SRL in various human in...

    Authors: Rainer Voisard, Svenja Zellmann, Fabian Müller, Felicitas Fahlisch, Lutz von Müller, Regine Baur, Jürgen Braun, Jürgen Gschwendt, Margaratis Kountides, Vinzenz Hombach and Joachim Kamenz
    Citation: BMC Cardiovascular Disorders 2007 7:15
  21. High blood pressure is an important determinant of cardiovascular disease risk. Treated hypertensives do not attain a risk level equivalent to normotensives. This may be a consequence of suboptimal blood press...

    Authors: Hari K Parthasarathy, Khamis Alhashmi, Alex D McMahon, Allan D Struthers, John MC Connell, Gordon T McInnes, Ian Ford and Thomas M MacDonald
    Citation: BMC Cardiovascular Disorders 2007 7:14
  22. We have developed a rat cell model for studying collagen type I production in coronary artery adventitial fibroblasts. Increased deposition of adventitial collagen type I leads to stiffening of the blood vesse...

    Authors: Cathleen Jenkins, Amy Milsted, Kathleen Doane, Gary Meszaros, Jonathan Toot and Daniel Ely
    Citation: BMC Cardiovascular Disorders 2007 7:13
  23. There have been few prospective studies examining the utility of routine exercise treadmill testing (ETT) early after percutaneous coronary intervention (PCI). The objective of this study was to examine the im...

    Authors: Mohan N Babapulle, Jean G Diodati, James C Blankenship, Thao Huynh, Sabrina Cugno, Radha Puri, Phuong A Nguyen and Mark J Eisenberg
    Citation: BMC Cardiovascular Disorders 2007 7:12
  24. In order to establish a consistent method for brachial artery reactivity assessment, we analyzed commonly used approaches to the test and their effects on the magnitude and time-course of flow mediated dilatio...

    Authors: Alon Peretz, Daniel F Leotta, Jeffrey H Sullivan, Carol A Trenga, Fiona N Sands, Mary R Aulet, Marla Paun, Edward A Gill and Joel D Kaufman
    Citation: BMC Cardiovascular Disorders 2007 7:11
  25. Studies suggest that Goal Directed Therapy (GDT) results in improved outcome following major surgery. However, there is concern that pre-emptive use of inotropic therapy may lead to an increased incidence of m...

    Authors: Rupert M Pearse, Deborah Dawson, Jayne Fawcett, Andrew Rhodes, R Michael Grounds and David Bennett
    Citation: BMC Cardiovascular Disorders 2007 7:10
  26. Exercise has been shown to be beneficial for selected patients with heart failure, but questions remain over its effectiveness, cost-effectiveness and uptake in a real world setting. This paper describes the d...

    Authors: Kate Jolly, Rod S Tayor, Gregory YH Lip, Sheila M Greenfield, Michael K Davies, Russell C Davis, Jonathan W Mant, Sally J Singh, Jackie T Ingram, Jane Stubley and Andrew J Stevens
    Citation: BMC Cardiovascular Disorders 2007 7:9
  27. The worse prognosis in patients without ST-elevation (non-STEMI) as compared to ST-elevation myocardial infarction (STEMI), may be due to treatment differences. We aimed to evaluate the differences in characte...

    Authors: Saman Rasoul, Jan Paul Ottervanger, Jan-Henk E Dambrink, Menko-Jan de Boer, Jan CA Hoorntje, AT Marcel Gosselink, Felix Zijlstra, Harry Suryapranata and Arnoud WJ van't Hof
    Citation: BMC Cardiovascular Disorders 2007 7:8
  28. Previous studies have shown that lesions in proximal left anterior descending coronary artery (LAD) may develop more restenosis after balloon angioplasty than lesions in other coronary segments. However, stent...

    Authors: Mohammad Alidoosti, Mojtaba Salarifar, Ali Mohammad Haji Zeinali, Seyed Ebrahim Kassaian and Maria Raissi Dehkordi
    Citation: BMC Cardiovascular Disorders 2007 7:7
  29. Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats that had the SHR Y chromosome locus crossed into their genome (SHR/y rat). A potential...

    Authors: Daniel Ely, Amy Milsted, Jason Bertram, Mat Ciotti, Gail Dunphy and Monte E Turner
    Citation: BMC Cardiovascular Disorders 2007 7:6
  30. In experimentally induced myocardial infarction, mild hypothermia (33–35°C) is beneficial if applied prior to ischemia or reperfusion. Hypothermia, when applied after reperfusion seems to confer little or no b...

    Authors: Goran K Olivecrona, Matthias Götberg, Jan Harnek, Jesper Van der Pals and David Erlinge
    Citation: BMC Cardiovascular Disorders 2007 7:5
  31. Endothelial dysfunction (ED) is functionally characterized by decreased vasorelaxation, increased thrombosis, increased inflammation, and altered angiogenic potential, has been intimately associated with the p...

    Authors: Chandrashekhar D Kamat, Jessica E Thorpe, Satyendra S Shenoy, Antonio Ceriello, Dixy E Green, Linda A Warnke and Michael A Ihnat
    Citation: BMC Cardiovascular Disorders 2007 7:4
  32. Peripheral arterial disease (PAD), defined by a low ankle-brachial index (ABI), is associated with an increased risk of cardiovascular events, but the risk of coronary heart disease (CHD) over the range of the...

    Authors: Beth D Weatherley, Jeanenne J Nelson, Gerardo Heiss, Lloyd E Chambless, A Richey Sharrett, F Javier Nieto, Aaron R Folsom and Wayne D Rosamond
    Citation: BMC Cardiovascular Disorders 2007 7:3
  33. Atherosclerosis is the leading cause of death in western societies and cigarette smoke is among the factors that strongly contribute to the development of this disease. The early events in atherogenesis are st...

    Authors: Hongwei Yuan, Lina S Wong, Monideepa Bhattacharya, Chongze Ma, Mohammed Zafarani, Min Yao, Matthias Schneider, Robert E Pitas and Manuela Martins-Green
    Citation: BMC Cardiovascular Disorders 2007 7:1
  34. Death of smooth muscle cells in the atherosclerotic plaques makes the plaques more prone to rupture, which can initiate an acute ischemic event. The development of atherosclerosis includes the migration of imm...

    Authors: Cristina D Ciornei, Hans Tapper, Anders Bjartell, Nils H Sternby and Mikael Bodelsson
    Citation: BMC Cardiovascular Disorders 2006 6:49
  35. Patients with diabetes and ischemic heart disease (IHD) are at high risk for adverse cardiac outcomes. Clinical practice guidelines recommend multiple cardioprotective medications to reduce recurrent events. W...

    Authors: P Michael Ho, David J Magid, Frederick A Masoudi, David L McClure and John S Rumsfeld
    Citation: BMC Cardiovascular Disorders 2006 6:48
  36. Cardiac mortality in Duchenne muscular dystrophy (DMD) has recently become important, because risk of respiratory failure has been reduced due to widespread use of the respirator. The cardiac involvement is ch...

    Authors: Naoko Yugeta, Nobuyuki Urasawa, Yoko Fujii, Madoka Yoshimura, Katsutoshi Yuasa, Michiko R Wada, Masao Nakura, Yoshiki Shimatsu, Masayuki Tomohiro, Akio Takahashi, Noboru Machida, Yoshito Wakao, Akinori Nakamura and Shin'ichi Takeda
    Citation: BMC Cardiovascular Disorders 2006 6:47
  37. Testosterone deficiency is a common occurrence in men with chronic heart failure (CHF) and may underpin features of advanced disease, including reduced skeletal muscle mass and fatigue. It is positively correl...

    Authors: John M Saxton, Irena Zwierska, Atish Mathur and Kevin S Channer
    Citation: BMC Cardiovascular Disorders 2006 6:46
  38. In the United States, over one-third of premature cardiac deaths occur outside of a hospital, without any transport prior to death. Transport prior to death is a strong, valid indicator of help-seeking behavio...

    Authors: Elizabeth Barnett, Steven Reader, Beverly G Ward and Michele L Casper
    Citation: BMC Cardiovascular Disorders 2006 6:45
  39. Chronic therapy with nitroglycerin (GTN) results in a rapid development of nitrate tolerance which is associated with an increased production of reactive oxygen species (ROS). According to recent studies, mito...

    Authors: Hanke Mollnau, Philip Wenzel, Matthias Oelze, Nicolai Treiber, Andrea Pautz, Eberhard Schulz, Swenja Schuhmacher, Kurt Reifenberg, Dirk Stalleicken, Karin Scharffetter-Kochanek, Hartmut Kleinert, Thomas Münzel and Andreas Daiber
    Citation: BMC Cardiovascular Disorders 2006 6:44
  40. Heart failure is the most common cause of hospitalization among adults over 65. Over 60% of patients die within 10 years of first onset of symptoms. The objective of this study is to determine the effectivenes...

    Authors: Aleksandra Jovicic, Jayna M Holroyd-Leduc and Sharon E Straus
    Citation: BMC Cardiovascular Disorders 2006 6:43
  41. Cigarette smoking is an established causal factor for atherosclerosis. However, the smoking effect on different echogenic components of carotid arterial wall measured by ultrasound is not well elucidated.

    Authors: Amy Z Fan, Maura Paul-Labrador, C Noel Bairey Merz, Carlos Iribarren and James H Dwyer
    Citation: BMC Cardiovascular Disorders 2006 6:42
  42. Diabetes is an important predictor of mortality patients with ACS. However, little is known about the association between diabetes and health status after ACS. The objective of this study was to examine the as...

    Authors: Pamela N Peterson, John A Spertus, David J Magid, Fredrick A Masoudi, Kimberly Reid, Richard F Hamman and John S Rumsfeld
    Citation: BMC Cardiovascular Disorders 2006 6:41
  43. Hormone therapy, oral contraceptives, and tamoxifen increase the risk of thrombotic disease. These compounds also reduce plasma content of tissue factor pathway inhibitor-1 (TFPI), which is the physiological i...

    Authors: Anders EA Dahm, Nina Iversen, Baard Birkenes, Anne Hansen Ree and Per Morten Sandset
    Citation: BMC Cardiovascular Disorders 2006 6:40
  44. The coexistence of type 2 diabetes mellitus and hypertension increases the risk of cardiovascular diseases. The U.K. Prospective Diabetes Study has shown that blood pressure control as well as blood glucose co...

    Authors: Ryuzo Kawamori, Hiroyuki Daida, Yasushi Tanaka, Katsumi Miyauchi, Akira Kitagawa, Dobun Hayashi, Junji Kishimoto, Shunya Ikeda, Yutaka Imai and Tsutomu Yamazaki
    Citation: BMC Cardiovascular Disorders 2006 6:39
  45. Hyperhomocysteinemia is known as an independent risk factor of atherosclerosis, but the probable role of hyperhomocysteinemia in premature Coronary Artery Disease (CAD) is not well studied. The aim of this stu...

    Authors: Saeed Sadeghian, Faramarz Fallahi, Mojtaba Salarifar, Gholamreza Davoodi, Mehran Mahmoodian, Nader Fallah, Soodabeh Darvish and Abbasali Karimi
    Citation: BMC Cardiovascular Disorders 2006 6:38
  46. Incomplete drug regimen compliance (DRC) and white-coat hypertension are two of several possible causes of uncontrolled hypertension. Therefore the aim of the present study was to compare DRC in hypertensives ...

    Authors: Thomas Mengden, Hans Vetter, Eric Tousset and Sakir Uen
    Citation: BMC Cardiovascular Disorders 2006 6:36
  47. Impaired vascular function occurs early in atherogenesis. Brachial flow mediated dilatation (FMD) is a non-invasive measure of vascular function and may be an important marker of preclinical atherosclerosis. D...

    Authors: Tatjana Rundek, Rameet Hundle, Elizabeth Ratchford, Romel Ramas, Robert Sciacca, Marco R Di Tullio, Bernadette Boden-Albala, Yumiko Miyake, Mitchell SV Elkind, Ralph L Sacco and Shunichi Homma
    Citation: BMC Cardiovascular Disorders 2006 6:35

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