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  1. Endovascular treatment of patients with Marfan syndrome (MFS) is not recommended. Hybrid procedures such as frozen elephant trunk (FET), which combines stent-graft deployment with an integrated non-stented fab...

    Authors: Kazimierz Jan Widenka, Monika Kosiorowska, Heinz Jakob, Davide Pacini, Wolfgang Hemmer, Martin Grabenwoeger, Thanos Sioris, Anton Moritz and Konstantinos Tsagakis
    Citation: BMC Cardiovascular Disorders 2022 22:333
  2. Rumpel Leede sign (RLS) is a clinical presentation observed at the extremities due to pressure applied externally. The appearance ranges from scattered pin-point rashes to an entire arm covered with petechial ...

    Authors: Yang Gui, JingYa Wang, Lifang Ye, GuangXin Pen and Lihong Wang
    Citation: BMC Cardiovascular Disorders 2022 22:332
  3. Sleep apnea is a risk factor for atrial fibrillation (AF) but it is underdiagnosed. Whether obstructive sleep apnea (OSA) is correlated with thrombotic risk in AF remains unclear. The aim of the present study ...

    Authors: Wei Xu, Yan-min Yang, Jun Zhu, Shuang Wu, Juan Wang, Han Zhang, Xing-hui Shao, Ran Mo, Jiang-shan Tan and Jing-yang Wang
    Citation: BMC Cardiovascular Disorders 2022 22:331
  4. More than 50% of patients admitted for acute heart failure are discharged with residual pulmonary congestion. Residual pulmonary congestion at discharge is associated with rehospitalization and death within 6 ...

    Authors: I. Rattarasarn, T. Yingchoncharoen and T. Assavapokee
    Citation: BMC Cardiovascular Disorders 2022 22:330
  5. Traditional angiography only displays two-dimensional images of the coronary arteries during stent implantation. However, intravascular imaging can show the structure of the vascular wall, plaque characteristi...

    Authors: Ying Niu, Nan Bai, Ying Ma, Peng-Yu Zhong, Yao-Sheng Shang and Zhi-Lu Wang
    Citation: BMC Cardiovascular Disorders 2022 22:327
  6. Percutaneous left atrial appendage (LAA) occlusion is effective for stroke prevention in patients with atrial fibrillation. LAA can have a complex anatomy, such as multiple lobes or a large orifice, which may ...

    Authors: Hong-Da Zhang, Ming Yang, Yang-Bo Xing, Si-Xian Weng, Lei Ding, Xiao-Tong Ding, Li-Xing Hu, Ying-Jie Qi, Feng-Yuan Yu, Jing-Tao Zhang, Pi-Hua Fang, Wei Hua, Shu Zhang and Min Tang
    Citation: BMC Cardiovascular Disorders 2022 22:326
  7. X-ray fluoroscopy has been the primary cardiac imaging modality in permanent pacemaker implantation (PPI) operations, but it inevitably results in radiation exposure for both operators and patients. Fluoroscop...

    Authors: Peng Wang, Guang-Sheng Wei, Jun-Hua Wang, Yan-Jie Cao, Wei-Wei Zhu, Hang Shen, Zhi-Yue Zhang, Li Ai and Meng Wang
    Citation: BMC Cardiovascular Disorders 2022 22:325
  8. Authors: Tal Abu, Amos Levi, David Hasdai, Mordechai R. Kramer, Tamir Bental, Tali Bdolah‑Abram, Arthur Shiyovich, Abed Samara, Hana Vaknin‑Assa, Leor Perl, Dror Rosengarten, Yaron Shapira, Ran Kornowski and Keren Skalsky
    Citation: BMC Cardiovascular Disorders 2022 22:324

    The original article was published in BMC Cardiovascular Disorders 2022 22:53

  9. Disseminated intravascular coagulation (DIC) is a critical and rare complication after thoracic endovascular aortic repair (TEVAR) of type B aortic dissection. The optimal treatment of aortic dissection-relate...

    Authors: Hanbo Liu, Yi Liu and Jifu Lai
    Citation: BMC Cardiovascular Disorders 2022 22:323
  10. Studies involving the association of blood albumin with prognosis in patients with chronic kidney disease (CKD) during intensive care unit (ICU) were scarce.

    Authors: Fengming Huang, Jinmao Fan, Xin Wan, Huogen Liu, Yundi Shi, Hailin Shu, Ying Liu, Tongan Lu, Zhenbin Gong and Ling Gu
    Citation: BMC Cardiovascular Disorders 2022 22:322
  11. Endothelial and microvascular dysfunction are pivotal causes of major adverse cardiac events predicted by coronary flow reserve (CFR). Extracellular Vesicles (EVs) have been studied extensively in the pathophy...

    Authors: Kreema James, Paulina Bryl-Gorecka, Björn Olde, Olof Gidlof, Kristina Torngren and David Erlinge
    Citation: BMC Cardiovascular Disorders 2022 22:321
  12. The pathogenic mechanism of dilated cardiomyopathy (DCM) remains to be defined. This study aimed to identify hub genes and immune cells that could serve as potential therapeutic targets for DCM.

    Authors: Chenggang Fang, Zhan Lv, Zhimin Yu, Kexin Wang, Chengkai Xu, Yixuan Li and Yanggan Wang
    Citation: BMC Cardiovascular Disorders 2022 22:320
  13. China has experienced a continuing increase in hypertension prevalence over the past few decades, especially in rural areas. The paper aims to examine the variation of urban–rural disparities in hypertension p...

    Authors: Haozhe Cheng, Yiran Gu, Xiaochen Ma, Haoqing Tang and Xiaoyun Liu
    Citation: BMC Cardiovascular Disorders 2022 22:319
  14. The increase of low-density lipoprotein cholesterol (LDL-C) is widely accepted as an important factor in the occurrence of atherosclerosis. In recent years, the guidelines have recommended non-high density lip...

    Authors: Po Gao, Xiang Wen, Qiaoyun Ou and Jing Zhang
    Citation: BMC Cardiovascular Disorders 2022 22:318
  15. The efficacy and validity of excimer laser ablation (ELA) in the in-stent restenosis (ISR) has been confirmed. However, its application in de novo atherosclerotic lesions of lower extremity artery disease (LEA...

    Authors: Xiaolang Jiang, Longhua Fan, Bin Chen, Junhao Jiang, Jianjun Liu, Guanyu Qiao, Shuai Ju, Yun Shi, Tao Ma, Changpo Lin, Gang Fang, Daqiao Guo, Xin Xu, Zhihui Dong and Weiguo Fu
    Citation: BMC Cardiovascular Disorders 2022 22:317
  16. Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the...

    Authors: Mohammadreza Edraki, Mohammadjavad Nobakhti, Amir Naghshzan, Hamid Amoozgar, Ahmadali Amirghofran, Bahram Ghasemzadeh, Elahe Nirooie, Nima Mehdizadegan, Hamid Mohammadi and Kambiz Keshavarz
    Citation: BMC Cardiovascular Disorders 2022 22:315

    The Correction to this article has been published in BMC Cardiovascular Disorders 2022 22:382

  17. The prevalence and mortality of cardiovascular diseases remain ranked first worldwide. Myocardial infarction (MI) is the central cause of death from cardiovascular diseases, seriously endangering human health....

    Authors: Ming-Jie Li, Shi-Bai Yan, Hao Dong, Zhi-Guang Huang, Dong-Ming Li, Yu-lu Tang, Yan-Fang Pan, Zhen Yang, Hong-Bo Pan and Gang Chen
    Citation: BMC Cardiovascular Disorders 2022 22:314
  18. Several studies have reported that NFKB1 gene rs28362491 polymorphism was associated with susceptibility to coronary heart disease in populations of different genetic backgrounds. To date, there have been no stud...

    Authors: Jun-Yi Luo, Fen Liu, Tong Zhang, Ting Tian, Fan Luo, Xiao-Mei Li and Yi-Ning Yang
    Citation: BMC Cardiovascular Disorders 2022 22:313
  19. Hybrid activation mapping is a novel tool to correct for spatial displacement of the mapping catheter due to asymmetrical contraction of myocardium during premature ventricular contractions (PVC). The aim of t...

    Authors: M. Nies, R. Schleberger, L. Dinshaw, N. Klatt, P. Muenkler, C. Jungen, L. Rottner, M. D. Lemoine, B. Reißmann, A. Rillig, A. Metzner, P. Kirchhof and C. Meyer
    Citation: BMC Cardiovascular Disorders 2022 22:312
  20. Non-valvular atrial fibrillation (NVAF) significantly increases the risk of stroke. Although there is availability of prediction models, their ability to predict the risk of stroke in NVAF patients remains sub...

    Authors: Shikun Sun, Bo Su, Jia Lin, Caiming Zhao and Changsheng Ma
    Citation: BMC Cardiovascular Disorders 2022 22:311
  21. The molecular mechanisms of protective effect of metformin (Met) on ischemic myocardium have not been fully understood. This study aims to evaluate the cardioprotective effect of metformin on myocardial ischem...

    Authors: Hang Su, Diyu Lu, Mingkui Shen, Li Feng and Chuangye Xu
    Citation: BMC Cardiovascular Disorders 2022 22:310
  22. Cardiovascular diseases (CVDs) were the number one cause of death in Iran. The main risk factors of CVDs include unhealthy lifestyles, insulin resistance, hypertension (HTN), and hyperlipidemia. Given that the...

    Authors: Nader Saki, Majid Karandish, Bahman Cheraghian, Habib Heybar, Seyed Jalal Hashemi and Maryam Azhdari
    Citation: BMC Cardiovascular Disorders 2022 22:309
  23. Inflammation plays a critical role in acute myocardial infarction (AMI). Recent studies have shown the value of hematologic indicators in MI risk stratification and prognostic assessment. However, the associat...

    Authors: Yuanyuan Zhao, Chunshu Hao, Xiangwei Bo, Zhengri Lu, Hao Qian and Lijuan Chen
    Citation: BMC Cardiovascular Disorders 2022 22:308
  24. Few prognostic risk scores (PRSs) have been routinely used in acute decompensated heart failure (ADHF). We, therefore, externally validated three published PRSs (3A3B, AHEAD, and OPTIME-CHF) and derived a new ...

    Authors: Hong-Liang Zhao, Xiao-Li Gao, Ying-Hua Liu, Sen-Lin Li, Qi Zhang, Wei-Chao Shan, Qun Zheng, Jiang Zhou, Yong-Zheng Liu, Li Liu, Nan Guo, Hong-Sen Tian, Qing-Min Wei, Xi-Tian Hu, Ying-Kai Cui, Xue Geng…
    Citation: BMC Cardiovascular Disorders 2022 22:307
  25. Postoperative pneumonia (PP) is one of the most common complications after cardiac surgery. This study was designed to access the diagnostic value of interleukin-6 (IL-6) for pneumonia within the first 5 days ...

    Authors: Wei Chen, Kai Zhong, Yan Guan, Hai Tao Zhang, He Zhang, Tuo Pan, Jun Pan and Dong Jin Wang
    Citation: BMC Cardiovascular Disorders 2022 22:306
  26.  Mitral valve prolapse (MVP) is an etiologically heterogeneous disorder. Early diagnosis and prompt treatment of the underlying disease are of great significance. Herein, we present a rare case of MVP caused b...

    Authors: Xuefeng Wang, Xiaorong Xia, Weiyi Huang, Xin Li and Yingcai Liu
    Citation: BMC Cardiovascular Disorders 2022 22:304
  27. The variant of ALDH2 was thought to be associated with Acute Myocardial Infarction (AMI) due to the consumption of alcohol. This study focused on how ALDH2 variant acts as an independent risk factor for AMI, r...

    Authors: Qixia Jiang, Xiaoguang Li, Rukun Chen, Chuhong Wang, Xin Liu and Xingyu Wang
    Citation: BMC Cardiovascular Disorders 2022 22:303
  28. One-staged surgical treatment of aortic coarctation combined with cardiac anomalies is challenging. We aim to evaluate the feasibility of bilateral aortofemoral bypass technique in one-staged surgery treating ...

    Authors: Hongyuan Lin, Yi Chang, Xiangyang Qian, Cuntao Yu and Xiaogang Sun
    Citation: BMC Cardiovascular Disorders 2022 22:302
  29. In the setting of ST-segment elevation myocardial infarction (STEMI), the faster and stronger antiplatelet action of ticagrelor compared to clopidogrel, as well as its pleiotropic effects, could result in a gr...

    Authors: Stylianos Petousis, Michalis Hamilos, Konstantinos Pagonidis, Panos Vardas, Georgios Lazopoulos, Ioannis Anastasiou, Evangelos Zacharis, George Kochiadakis and Emmanouil Skalidis
    Citation: BMC Cardiovascular Disorders 2022 22:301
  30. Mounting evidence indicates an association between endothelial dysfunction and the coronary slow flow phenomenon (CSFP). In the present study, we aimed to evaluate the possible role of endothelial nitric oxide...

    Authors: Yeganeh Karimi, Fatemeh Sehati, Ali Sarreshtedari, Mina Mirzad, Yasaman Khalili, Reza Kiani, Elham Taheri Bajgan, Maryam Hosseini Moghadam, Farzaneh Mehrvarz, Hooman Bakhshandeh, Maryam Parham, Mahshid Malakootian and Parham Sadeghipour
    Citation: BMC Cardiovascular Disorders 2022 22:300
  31. Postoperative delirium is a common complication of cardiac surgery associated with higher morbidity, longer hospital stay, risk of cognitive decline, dementia, and mortality. Geriatric patients, patients under...

    Authors: Monika Sadlonova, Jonathan Vogelgsang, Claudia Lange, Irina Günther, Adriana Wiesent, Charlotte Eberhard, Julia Ehrentraut, Mareike Kirsch, Niels Hansen, Hermann Esselmann, Charles Timäus, Thomas Asendorf, Benedict Breitling, Mohammed Chebbok, Stephanie Heinemann, Christopher Celano…
    Citation: BMC Cardiovascular Disorders 2022 22:299
  32. Coronary artery disease (CAD) is the most common heart disease. Several studies have shown association between some polymorphism in different genes with CAD. Finding this association can be used in order to ea...

    Authors: Sima Rayat, Nasim Ramezanidoraki, Nima Kazemi, Mohammad H. Modarressi, Masoumeh Falah, Safoura Zardadi and Saeid Morovvati
    Citation: BMC Cardiovascular Disorders 2022 22:298
  33. The association between prothrombin time-international normalized ratio (PT-INR) and long-term prognosis among patients with coronary artery disease (CAD) without atrial fibrillation or anticoagulant therapy w...

    Authors: Liwei Liu, Ming Ying, Shiqun Chen, Qiang Li, Guanzhong Chen, Huanqiang Li, Ziling Mai, Yibo He, Bo Wang, Danyuan Xu, Zhidong Huang, Xiaoming Yan, Ning Tan, Zhujun Chen, Jin Liu and Yong Liu
    Citation: BMC Cardiovascular Disorders 2022 22:297
  34. The primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy for ST-segment elevation myocardial infarction (STEMI). The pharmacoinvasive strategy (PIs) is a reasonable alternati...

    Authors: Manuel Chacón-Diaz, Piero Custodio-Sánchez, Paol Rojas De la Cuba, Germán Yábar-Galindo, René Rodríguez-Olivares, David Miranda-Noé, Luis Marcos López-Rojas and Akram Hernández-Vásquez
    Citation: BMC Cardiovascular Disorders 2022 22:296
  35. The benefits of cardiac rehabilitation (CR) after acute coronary syndrome (ACS) are well established. However, the relative benefit of CR in those with comorbidities, including diabetes, is not well understood...

    Authors: Birgitte Bitsch Gadager, Lars Hermann Tang, Maiken Bay Ravn, Patrick Doherty, Alexander Harrison, Jan Christensen, Rod S. Taylor, Ann-Dorthe Zwisler and Thomas Maribo
    Citation: BMC Cardiovascular Disorders 2022 22:295
  36. Little is known about the evolution of peripheral arterial disease (PAD) since diagnosis and its association with glycemic and lipid control in patients with Type 2 Diabetes Mellitus (T2DM).

    Authors: João Soares Felício, Franciane Trindade Cunha de Melo, Giovana Miranda Vieira, Vitória Teixeira de Aquino, Fernanda de Souza Parente, Wanderson Maia da Silva, Nivin Mazen Said, Emanuele Rocha da Silva, Ana Carolina Contente Braga de Souza, Maria Clara Neres Iunes de Oliveira, Gabriela Nascimento de Lemos, Ícaro José Araújo de Souza, Angélica Leite de Alcântara, Lorena Vilhena de Moraes, João Felício Abrahão Neto, Natércia Neves Marques de Queiroz…
    Citation: BMC Cardiovascular Disorders 2022 22:294
  37. Hypertension is defined as two or more measurements of systolic blood pressure equal to or greater than 130 mm Hg or diastolic blood pressure equal to or greater than 80 mm Hg. At the community level, symptoms...

    Authors: Tadele Lankrew Ayalew, Belete Gelaw Wale and Bitew Tefera Zewudie
    Citation: BMC Cardiovascular Disorders 2022 22:293
  38. Patients who undergo heart surgery are exposed to mental and physical difficulties after discharge from hospital. They often need support and follow-up after discharge. The use of educational approaches or sol...

    Authors: Leila Shahmoradi, Nafiseh Rezaei, Sorayya Rezayi, Mitra Zolfaghari and Babak Manafi
    Citation: BMC Cardiovascular Disorders 2022 22:292
  39. Device-associated thrombus are potential causes for thromboembolic events post left atrial appendage closure (LAAC), and correlated with the complete endothelialization of the device surface. Our aim was to ev...

    Authors: Xiaoxia Wu, Dongxing Ma, Tao Wan, Yuezhi Meng, Yilong Chen, Yejia Shen and Wei Huang
    Citation: BMC Cardiovascular Disorders 2022 22:291
  40. This prospective, multi-center, intensive monitoring study aimed to systematically assess the occurrence of adverse events (AEs) and adverse drug reactions (ADRs), especially thrombocytopenia and bleeding, as ...

    Authors: Haijun Zheng, Zhonghua Wang, Qi Li, Yingxin Zhao, Yin Liu, Aiming Chen, Jianping Deng and Guohai Su
    Citation: BMC Cardiovascular Disorders 2022 22:290
  41. We lack data on the effect of single premature ventricular contractions (PVCs) on the clinical and echocardiographic response after cardiac resynchronization therapy (CRT) device implantation. We aimed to asse...

    Authors: Eperke Dóra Merkel, András Mihaly Boros, Walter Richárd Schwertner, Anett Behon, Attila Kovács, Bálint Károly Lakatos, László Gellér, Annamária Kosztin and Béla Merkely
    Citation: BMC Cardiovascular Disorders 2022 22:289
  42. Acute kidney injury (AKI) stage 3, one of the most severe complications in patients with heart transplantation (HT), is associated with substantial morbidity and mortality. We aimed to develop a machine learni...

    Authors: Tingyu Li, Yuelong Yang, Jinsong Huang, Rui Chen, Yijin Wu, Zhuo Li, Guisen Lin, Hui Liu and Min Wu
    Citation: BMC Cardiovascular Disorders 2022 22:288
  43. Mechanical damage plays an essential role in the progression of atherosclerosis. Piezo1 is a new mechanically sensitive ion channel. The present study investigated the vascular smooth muscle cells (VSMCs) apop...

    Authors: Qing Yin, Guangyao Zang, Nannan Li, Chenchen Sun and Rongzeng Du
    Citation: BMC Cardiovascular Disorders 2022 22:287
  44. Circulating microRNAs (miRNAs) are considered a hot spot of research that can be employed for monitoring and/or diagnostic purposes in coronary artery disease (CAD). Since different disease features might be r...

    Authors: Hoda Y. Abdallah, Ranya Hassan, Ahmed Fareed, Mai Abdelgawad, Sally Abdallah Mostafa and Eman Abdel-Moemen Mohammed
    Citation: BMC Cardiovascular Disorders 2022 22:286
  45. Cardiovascular disease is the world major cause of death. There is sufficient evidence that patients with coronary heart disease (CHD) experience poor quality of life. Health literacy and self efficacy are mod...

    Authors: Shaoying Du, Zhimin Feng, Wen Wang, Licong Tian and Yan Wang
    Citation: BMC Cardiovascular Disorders 2022 22:285
  46. This study aims to construct a reliable diagnostic model for coronary artery disease (CAD) patients and explore its potential mechanism by consensus molecular subtypes of ferroptosis-related genes.

    Authors: Lina Ding, Fei Long, Dan An, Jing Liu and Guannan Zhang
    Citation: BMC Cardiovascular Disorders 2022 22:283

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