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  1. Familial hypercholesterolemia (FH) can lead to premature coronary heart disease. Anticardiolipin antibody may be a contributor for thrombosis. Here, we report an adult with possible FH suffered from premature ...

    Authors: Xin Su, Aqian Wang, Hai Zhu, Hongling Su, Yichao Duan, Shanlian Wu, Min Zhang, Yan Huang, Xing Zhou and Yunshan Cao

    Citation: BMC Cardiovascular Disorders 2019 19:156

    Content type: Case report

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  2. Genetic and environment play a significant role in the etiology of essential hypertension (EH). Recently STK39 rs3754777, ATP2B1 rs2681472 and rs17249754 have been associated with BP variation and hypertension. I...

    Authors: Herman Karim Sombié, Jonas Koudougou Kologo, Daméhan Tchelougou, Serge Yannick Ouédraogo, Abdoul Karim Ouattara, Tegwindé Rebecca Compaoré, Bolni Marius Nagalo, Abel Pegdwendé Sorgho, Issoufou Nagabila, Serge Théophile Soubeïga, Florencia Wendkuuni Djigma, Albert Théophane Yonli, Patrice Zabsonré, Hassanata Millogo and Jacques Simporé

    Citation: BMC Cardiovascular Disorders 2019 19:155

    Content type: Research article

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  3. We investigated changes of cortical thickness and its association with cognitive performance in patients with high-grade carotid artery stenosis without ischemic brain lesions.

    Authors: Alina Nickel, Simon Kessner, Andreas Niebuhr, Julian Schröder, Caroline Malherbe, Felix Fischer, Marlene Heinze, Bastian Cheng, Jens Fiehler, Hans Pinnschmidt, Axel Larena-Avellaneda, Christian Gerloff and Götz Thomalla

    Citation: BMC Cardiovascular Disorders 2019 19:154

    Content type: Research article

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  4. Fatty acid-binding protein 4 (FABP4) (also known as adipocyte FABP or adipocyte P2) is expressed in adipocytes, macrophages, and capillary endothelial cells. Previous studies have shown associations among plas...

    Authors: Chao-Ping Wang, Chia-Chang Hsu, Wei-Chin Hung, Teng-Hung Yu, Cheng-Ching Wu, I-Ting Tsai, Wei-Hua Tang, Fu-Mei Chung, Jer-Yiing Houng, Yau-Jiunn Lee and Yung-Chuan Lu

    Citation: BMC Cardiovascular Disorders 2019 19:153

    Content type: Research article

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  5. Contrast-induced nephropathy (CIN) is common after percutaneous coronary intervention (PCI) and always leads to a poor prognosis. Compared with conventional detection methods, either high-sensitivity C-reactiv...

    Authors: Guoqiang Gu, Xuechao Yuan, Yaqing Zhou, Demin Liu and Wei Cui

    Citation: BMC Cardiovascular Disorders 2019 19:152

    Content type: Research article

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  6. Continuous-flow left ventricular assist devices (LVADs) improve survival and morbidity in patients with stage D heart failure. Management of LVADs for longer durations is necessary in some clinical settings, a...

    Authors: Chie Bujo, Eisuke Amiya, Masaru Hatano, Masaki Tsuji, Hisataka Maki, Yumiko Hosoya, Emi Fujii, Tatsuya Kamon, Toshiya Kojima, Kan Nawata, Osamu Kinoshita, Mitsutoshi Kimura, Minoru Ono and Issei Komuro

    Citation: BMC Cardiovascular Disorders 2019 19:151

    Content type: Case report

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  7. Although invasively measured blood pressure (invBP) is regarded as a “gold standard” in critically ill cardiac patients, the non-invasive BP is still widely used, at least at the initiation of medical care. Th...

    Authors: Jitka Seidlerová, Pavlína Tůmová, Richard Rokyta and Milan Hromadka

    Citation: BMC Cardiovascular Disorders 2019 19:150

    Content type: Research article

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  8. The aim of this study was to investigate the relationship between Talin-1 and stability of carotid atherosclerosis plaque and also find out the role of miRNA, as an upstream regulator, in regulating the expres...

    Authors: Xiaolong Wei, Yudong Sun, Tonglei Han, Jiang Zhu, Yongfu Xie, Shiying Wang, Yani Wu, Yinxing Fan, Xiuli Sun, Jian Zhou, Zhiqing Zhao and Zaiping Jing

    Citation: BMC Cardiovascular Disorders 2019 19:149

    Content type: Research article

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  9. Cardiovascular disease (CVD) is the leading cause of mortality worldwide; however, the epidemiology of CVD among nationals from the United Arab Emirates (UAE) remains unknown. This study aimed to estimate the ...

    Authors: Saif Al-Shamsi, Dybesh Regmi and Romona D. Govender

    Citation: BMC Cardiovascular Disorders 2019 19:148

    Content type: Research article

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  10. Postoperative atrial fibrillation is the most common arrhythmia seen after cardiac surgery. We aimed to determine the effect of obesity and metabolic syndrome on postoperative atrial fibrillation, whether they...

    Authors: Ünsal Vural and Ahmet Arif Ağlar

    Citation: BMC Cardiovascular Disorders 2019 19:147

    Content type: Research article

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  11. Little is known about the ICD performance using enhanced detection algorithms in unselected, non-trial patients. Performance of recent generation ICD equipped with SmartShock™ technology (SST) for detection an...

    Authors: François Regoli, Denis Graf, Beat Schaer, Firat Duru, Peter Ammann, Lorenza Mangoni di S. Stefano, Barbara Naegli, Haran Burri, Rainer Zbinden, Nazmi Krasniqi and Martin Fromer

    Citation: BMC Cardiovascular Disorders 2019 19:146

    Content type: Research article

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  12. The relationship between vitamin D levels and peripheral arterial disease (PAD) remains unclear. We assessed the association of serum 25-hydroxyvitamin D (25(OH)D) levels with the prevalence of PAD in patients...

    Authors: Jing Yuan, Pu Jia, Lin Hua, Zhong Xin and Jin-Kui Yang

    Citation: BMC Cardiovascular Disorders 2019 19:145

    Content type: Research article

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  13. Using the current meta-analysis as well as systematic review, to determine the curative effect of Nicorandil in comparison of no Nicorandil after elective percutaneous coronary intervention(PCI) on patients.

    Authors: Xiao-Tao Zhao, Chun-Fei Zhang and Qing-Jie Liu

    Citation: BMC Cardiovascular Disorders 2019 19:144

    Content type: Research article

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  14. Cardiovascular diseases remain the top global killer, with nearly 80% of related mortalities occurring in developing countries. Over half of cardiovascular diseases’ mortality is due to coronary heart disease,...

    Authors: Mohannad Eid AbuRuz

    Citation: BMC Cardiovascular Disorders 2019 19:143

    Content type: Research article

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  15. Clinical trials have demonstrated that direct oral anticoagulants (DOACs) are at least non-inferior to warfarin in reducing the risk of stroke/systemic embolism (SE) among patients with non-valvular atrial fib...

    Authors: Kiran Gupta, Jeffrey Trocio, Allison Keshishian, Qisu Zhang, Oluwaseyi Dina, Jack Mardekian, Anagha Nadkarni and Thomas C Shank

    Citation: BMC Cardiovascular Disorders 2019 19:142

    Content type: Research article

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  16. CD36 is associated with regulation of lipid metabolism, atherosclerosis, and blood pressure. Moreover, its variation may be involved in the development of hypertension and/or coronary artery disease (CAD). The...

    Authors: Mohammad Amin Momeni-Moghaddam, Gholamreza Asadikaram, Hamed Akbari, Moslem Abolhassani, Mohammad Masoumi, Zahra Nadimy and Mohammad Khaksari

    Citation: BMC Cardiovascular Disorders 2019 19:140

    Content type: Research article

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  17. Biochemical marker has revolutionized the approach to the diagnosis of heart failure. However, it remains difficult to assess stability of the patient. As such, novel means of stratifying disease severity are ...

    Authors: Chao Gao, Shasha Zhao, Kun Lian, Baibing Mi, Rui Si, Zhijun Tan, Feng Fu, Shuai Wang, Rutao Wang, Xinliang Ma and Ling Tao

    Citation: BMC Cardiovascular Disorders 2019 19:139

    Content type: Research article

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  18. Catheter ablation (CA) and left atrial appendage closure (LAAC) have been combined into a novel one-stop procedure for patients with atrial fibrillation (AF). However, postoperative complications are relativel...

    Authors: Zhonglin Han, Xiang Wu, Zheng Chen, Wengqing Ji, Xuehua Liu, Yu Liu, Wencheng Di, Xiaohong Li, Hongsong Yu, Xinlin Zhang, Biao Xu, Rong Fang Lan and Wei Xu

    Citation: BMC Cardiovascular Disorders 2019 19:138

    Content type: Research article

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  19. Type 2 diabetes mellitus (T2DM) is one of the most prevalent cardiac and cerebrovascular risk factors. The study aimed to find a new way to investigate left ventricle (LV) systolic dysfunction in T2DM patients...

    Authors: Jun Huang, Hai-Ling Hu, Zi-Ning Yan, Li Fan, Yi-Fei Rui, Dan Shen and Jie Li

    Citation: BMC Cardiovascular Disorders 2019 19:137

    Content type: Research article

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  20. The purpose of this review is to examine the effect of Omega-3 Fatty acids on mortality, morbidity, and adverse events in patients with acute myocardial infarction (AMI).

    Authors: Federico Popoff, Giselle Balaciano, Ariel Bardach, Daniel Comandé, Vilma Irazola, Hugo Norberto Catalano and Ariel Izcovich

    Citation: BMC Cardiovascular Disorders 2019 19:136

    Content type: Research article

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  21. Effects of β-blockers on outcomes in patients with chronic heart failure (CHF) and atrial fibrillation (AF) is still in controversy.

    Authors: Tianyu Xu, Yuli Huang, Haobin Zhou, Yujia Bai, Xingfu Huang, Yunzhao Hu, Dingli Xu, Yuhui Zhang and Jian Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:135

    Content type: Research article

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  22. Treating patients in cardiac arrest (CA) with mechanical chest compressions (MCC) during percutaneous coronary intervention (PCI) is now routine in many coronary catheterization laboratories (cath-lab) and mor...

    Authors: Bjarne Madsen Hardig, Karl B. Kern and Henrik Wagner

    Citation: BMC Cardiovascular Disorders 2019 19:134

    Content type: Research article

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  23. After publication of the original article [1], the authors have notified us of a typing error in spelling Dr. Kabat’s name. The original publication has been corrected.

    Authors: Magdalena Fraczek-Jucha, Katarzyna Zbierska-Rubinkiewicz, Małgorzata Kabat, Krzysztof Plens, Radoslaw Rychlak, Jadwiga Nessler and Andrzej Gackowski

    Citation: BMC Cardiovascular Disorders 2019 19:133

    Content type: Correction

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    The original article was published in BMC Cardiovascular Disorders 2019 19:105

  24. Historically, the majority of insertable cardiac monitor (ICM) procedures were performed in the cardiac catheterization (cath) lab, electrophysiology (EP) lab, or operating room (OR). The miniaturization of IC...

    Authors: Prashanthan Sanders, Christopher Piorkowski, Johannes A. Kragten, Grahame K. Goode, Satish R. Raj, Trang Dinh, M. Rizwan Sohail, Rishi Anand, Angel Moya-Mitjans, Noreli Franco, Kurt Stromberg and John D. Rogers

    Citation: BMC Cardiovascular Disorders 2019 19:132

    Content type: Technical advance

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  25. Bone morphogenetic protein9 (BMP9) has been reported to have a role in vascular development. However, there is still a lack of information regarding the association between circulating BMP9 levels and cardiova...

    Authors: Rui Liu, Wenjing Hu, Xiaoqiang Li, Danlan Pu, Gangyi Yang, Hua Liu, Minghong Tan and Danping Zhu

    Citation: BMC Cardiovascular Disorders 2019 19:131

    Content type: Research article

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  26. Gamma-glutamyltransferase (GGT) is a new predictor of cardiovascular diseases. In this study, we aimed to determine its association with ventricular arrhythmias (VAs) in implantable cardioverter-defibrillator ...

    Authors: You Zhou, Shuang Zhao, Keping Chen, Wei Hua and Shu Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:129

    Content type: Research article

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  27. The association between mean platelet volume (MPV) and coronary plaque vulnerability in patients with non-ST-elevation ACS (NSTE-ACS) has not been investigated. We performed a retrospective study to evaluate t...

    Authors: Jun Wang, Xing Li, Jun Pu, Siyu Jin, Lu Jia, Xiaomei Li, Fen Liu and Yining Yang

    Citation: BMC Cardiovascular Disorders 2019 19:128

    Content type: Research article

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  28. Loop diuretics are recommended by clinical practice guidelines to treat volume overload in acute decompensated heart failure (ADHF). The effectiveness of switching furosemide to torsemide versus optimizing the...

    Authors: Alaa Rahhal, Mohamed Omar Saad, Kawthar Tawengi, Abed Al Raouf Assi, Masa Habra and Dalia Ahmed

    Citation: BMC Cardiovascular Disorders 2019 19:127

    Content type: Research article

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  29. Information on the role of intermittent fasting (IF) on pathologic cardiac remodeling is scarce. We compared the effects of IF before and after myocardial infarction (MI) on rat cardiac remodeling and survival.

    Authors: K. Okoshi, M. D. M. Cezar, M. A. M. Polin, J. R. Paladino Jr, P. F. Martinez, S. A. Oliveira Jr, A. R. R. Lima, R. L. Damatto, S. A. R. Paiva, L. A. M. Zornoff and M. P. Okoshi

    Citation: BMC Cardiovascular Disorders 2019 19:126

    Content type: Research article

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  30. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are assumed to be prognostic factors in many diseases such as inflammatory diseases, cardiovascular diseases and cancer. However, NLR...

    Authors: Lishan Wu, Shan Zou, Cantian Wang, Xuerui Tan and Min Yu

    Citation: BMC Cardiovascular Disorders 2019 19:125

    Content type: Research article

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  31. Guidelines recommend tight systolic blood pressure (SBP) control for favorable outcomes of type B aortic dissection (BAD) but are still limited by the optimal cut-off value of SBP. The purpose of this study wa...

    Authors: Nan Lu, Xiaojing Ma, Tan Xu, Zhuoqiao He, Bayi Xu, Qingfeng Xiong and Xuerui Tan

    Citation: BMC Cardiovascular Disorders 2019 19:124

    Content type: Research article

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  32. Despite currently available treatments, the burden of myocardial infarction (MI) morbidity and mortality remains prominent. The aim of this was to investigate the risk of developing subsequent cardiovascular e...

    Authors: Ville Kytö, Tuire Prami, Houssem Khanfir, Pål Hasvold, Eeva Reissell and Juhani Airaksinen

    Citation: BMC Cardiovascular Disorders 2019 19:123

    Content type: Research article

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  33. Postoperative atrial fibrillation (POAF) is a common complication in patients with obstructive hypertrophic cardiomyopathy (HOCM) who undergo surgical myectomy. POAF is associated with poor outcome. The role o...

    Authors: Changpeng Song, Shengwei Wang, Ying Guo, Xinxin Zheng, Jie Lu, Xiaonan Fang, Shuiyun Wang and Xiaohong Huang

    Citation: BMC Cardiovascular Disorders 2019 19:122

    Content type: Research article

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  34. Despite the availability and improvement in diagnostic and therapeutic interventions with proven benefits in reducing cardiovascular morbidity and mortality, control rates of hypertension remain poor and gross...

    Authors: Gebrewahd Bezabh Gebremichael, Kalayou Kidanu Berhe and Teklewoini Mariye Zemichael

    Citation: BMC Cardiovascular Disorders 2019 19:121

    Content type: Research article

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  35. Atrial fibrillation (AF) is caused by different mechanisms but current treatment strategies do not target these mechanisms. Stratified therapy based on mechanistic drivers and biomarkers of AF have the potenti...

    Authors: Winnie Chua, Christina L. Easter, Eduard Guasch, Alice Sitch, Barbara Casadei, Harry J. G. M. Crijns, Doreen Haase, Stéphane Hatem, Stefan Kääb, Lluis Mont, Ulrich Schotten, Moritz F. Sinner, Karla Hemming, Jonathan J. Deeks, Paulus Kirchhof and Larissa Fabritz

    Citation: BMC Cardiovascular Disorders 2019 19:120

    Content type: Study protocol

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  36. Emerging evidence suggests that patients with coronary artery disease carry an increased risk of developing malignancy, with deleterious effects on long-term prognosis. Our aim was to ascertain whether baselin...

    Authors: Giuseppe Berton, Rocco Cordiano, Fiorella Cavuto, Francesco Bagato, Heba Talat Mahmoud and Mattia Pasquinucci

    Citation: BMC Cardiovascular Disorders 2019 19:119

    Content type: Research article

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  37. Myocardial ischemia-reperfusion (IR) injury is a leading cause of death all over the world, so developing practical approaches to promote cardioprotection against IR injury is essential. Exercise training is a...

    Authors: Maral Ramez, Hamid Rajabi, Fatemeh Ramezani, Nasim Naderi, Amir Darbandi-Azar and Farinaz Nasirinezhad

    Citation: BMC Cardiovascular Disorders 2019 19:118

    Content type: Research article

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  38. Postoperative bleeding in cardiovascular surgery is a frequent and complicated situation for the surgical team, and may also be responsible for significant hospital expenditures. Fibrin glue are indicated in s...

    Authors: Amine Cheikh, Mohamed Rida Ajaja, Hicham Rhazali, Mustapha Bouatia, Ali Benomar, Anas Slaoui, Yahia Cherrah, Redouane Abouqal, Amine El Hassani and Younes Cheikhaoui

    Citation: BMC Cardiovascular Disorders 2019 19:117

    Content type: Research article

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  39. In recent years, studies have indicated that vitamin D [25(OH)D3] and other calcium-phosphate (Ca-P) metabolism parameters and their disturbances might be potential new factors that may influence health-related q...

    Authors: Olga Mozenska, Jacek Bil, Agnieszka Segiet and Dariusz A. Kosior

    Citation: BMC Cardiovascular Disorders 2019 19:116

    Content type: Research article

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  40. Previous studies reported that low level of oestradiol (E2) was associated with higher risk of cardiovascular disease (CVD). However, little study examined the relationship between E2 and CVD in longevous wome...

    Authors: Qiao Zhu, Yao Yao, Chao-Xue Ning, Xiao-Ping Chen, Fu-Xin Luan, Liang Liu, Qiong Liu, Na Wang, Fu Zhang and Ya-Li Zhao

    Citation: BMC Cardiovascular Disorders 2019 19:115

    Content type: Research article

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  41. Peripartum cardiomyopathy (PPCM) is a rare but potentially life-threatening complication of pregnancy. There is limited data regarding the predictors of persistent left ventricular (LV) systolic dysfunction. R...

    Authors: Firdevs Aysenur Ekizler and Serkan Cay

    Citation: BMC Cardiovascular Disorders 2019 19:114

    Content type: Research article

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  42. Warfarin is the standard of care and NOAC (Novel oral anticoagulants) are a group of newer drugs for such purposes. NOAC has a generally better profile (Clear interaction, less side effect, require less monito...

    Authors: Qiyu He, Chun-Yat Sze, Tin-Yau Shum, Guang Hao, Nga-Yin Belinda Wong, Tat-Hang Sin, Wei Wei and Sujian Xia

    Citation: BMC Cardiovascular Disorders 2019 19:113

    Content type: Research article

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  43. Impaired renal function increases the bleeding risk, leading to a conservative prescription and frequent discontinuation of oral anticoagulation in atrial fibrillation patients with chronic kidney disease (CKD...

    Authors: Blerim Luani, Conrad Genz, Joerg Herold, Andreas Mitrasch, Julius Mitusch, Marcus Wiemer, Alexander Schmeißer, Rüdiger C. Braun-Dullaeus and Thomas Rauwolf

    Citation: BMC Cardiovascular Disorders 2019 19:112

    Content type: Research article

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  44. Inflammation in myocardial infarction has a complex immunogenic origin and is suspected to be closely involved in its aetio-pathogenesis as well as outcome. In this study the objective was to further elucidate...

    Authors: Mitrakrishnan Rayno Navinan, Sepalika Mendis, Sumudu Wickramasinghe, Ambiga Kathirgamanathan, Tharanga Fernando and Jevon Yudhisdran

    Citation: BMC Cardiovascular Disorders 2019 19:111

    Content type: Research article

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  45. The rational length of stay following non-complicated percutaneous coronary intervention (PCI) for Non-ST elevation myocardial infarction (NSTEMI) patients remains controversial. Few studies have examined the ...

    Authors: Guozhong Wang, Quanming Zhao, Qing Cheng, Xiaoxia Zhang, Lei Tian and Xiaofan Wu

    Citation: BMC Cardiovascular Disorders 2019 19:109

    Content type: Research article

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  46. Coronary artery disease (CAD) is associated with poorer outcomes after aortic valve replacement (AVR). For high-risk patients with complex CAD, combined transcatheter aortic valve replacement (TAVR) plus off-p...

    Authors: Hardy Baumbach, Eva R. Schairer, Kristina Wachter, Christian Rustenbach, Samir Ahad, Alina Stan, Stephan Hill, Peter Bramlage, Ulrich F. W. Franke and Tim Schäufele

    Citation: BMC Cardiovascular Disorders 2019 19:108

    Content type: Research article

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  47. Recent studies have indicated that monocyte chemoattractant protein-1 (MCP-1) plays an important role in the initiation and progression of ischaemic heart disease. However, no previous research has investigate...

    Authors: Yong Zhu, Chengping Hu, Yu Du, Jianwei Zhang, Jinxing Liu, Hongya Han and Yingxin Zhao

    Citation: BMC Cardiovascular Disorders 2019 19:107

    Content type: Research article

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