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  1. The optimal duration of oral anticoagulant therapy for patients with venous thromboembolism (VTE) remains highly uncertain in clinical practice. It is essential to accurately assess the effect of anticoagulant...

    Authors: Wei Wang, Yang Su, Chunyan Wu, Yuxi Sun, Neng Dai, Wei Chen, Jie Zhang, Yawei Xu, Ralph G. Brindis, Dachun Xu and Jue Li

    Citation: BMC Cardiovascular Disorders 2020 20:53

    Content type: Research article

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  2. Three-dimensional electroanatomic mapping systems have demonstrated a significant reduction in radiation exposure during radiofrequency catheter ablation procedures. We aimed to investigate the safety, feasibi...

    Authors: Guangzhi Chen, Yan Wang, Riccardo Proietti, Xunzhang Wang, Feifan Ouyang, Chang Sheng Ma, Rong Hui Yu, Chunxia Zhao, Kezhong Ma, Jie Qiu, Qigong Liu and Dao Wen Wang

    Citation: BMC Cardiovascular Disorders 2020 20:48

    Content type: Research article

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  3. Cardiac surgery for prosthetic valve endocarditis (PVE) is associated with substantial mortality. We aimed to analyze 30-day and 1-year outcome in patients undergoing surgery for PVE and sought to identify pre...

    Authors: Carolyn Weber, Parwis B. Rahmanian, Melanie Nitsche, Asmae Gassa, Kaveh Eghbalzadeh, Stefanie Hamacher, Julia Merkle, Antje-Christin Deppe, Anton Sabashnikov, Elmar W. Kuhn, Oliver J. Liakopoulos and Thorsten Wahlers

    Citation: BMC Cardiovascular Disorders 2020 20:47

    Content type: Research article

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  4. The current diagnostic methods and treatments still fail to lower the incidence of anthracycline-induced cardiotoxicity effectively. In this study, we aimed to (1) analyze the cardiotoxicity-related genes afte...

    Authors: Wang Yadi, Chen Shurui, Zhang Tong, Chen Suxian, Tong Qing and He Dongning

    Citation: BMC Cardiovascular Disorders 2020 20:43

    Content type: Research article

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  5. We evaluated adherence to dosing criteria for patients with atrial fibrillation (AF) taking dabigatran or rivaroxaban and the impact of off-label dosing on thromboembolic and bleeding risk.

    Authors: Alexandros Briasoulis, Yubo Gao, Chakradhari Inampudi, Paulino Alvarez, Rabea Asleh, Elizabeth Chrischilles, Enrique C. Leira and Mary Vaughan-Sarrazin

    Citation: BMC Cardiovascular Disorders 2020 20:42

    Content type: Research article

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  6. Hypertension is a major cardiovascular illness worldwide with many underlying causes. The role of trace elements selenium, copper, and zinc in hypertension is uncertain. The objective of this study was to eval...

    Authors: Mrigendra M. Bastola, Craig Locatis, Richard Maisiak and Paul Fontelo

    Citation: BMC Cardiovascular Disorders 2020 20:45

    Content type: Research article

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  7. Endothelial dysfunction may play a key role in non-obstructive coronary artery atherosclerosis. Our study aimed to evaluate the vascular endothelial function and its influencing factors in patients with non-ob...

    Authors: Yin-Ping Li, Zhen-Xing Fan, Jing Gao, Xi-Peng Sun, Guo-Hua Zhu, Ying-Hua Zhang, Jin Si, Xue-Bing Zuo, Zhi Liu, Qi Hua and Jing Li

    Citation: BMC Cardiovascular Disorders 2020 20:40

    Content type: Research article

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  8. Although mineral metabolism disorder influences cardiac valvular calcification (CVC), few previous studies have examined the effects of non-calcium-containing and calcium-containing phosphate binders on CVC in...

    Authors: Kentaro Watanabe, Hideki Fujii, Keiji Kono, Shunsuke Goto and Shinichi Nishi

    Citation: BMC Cardiovascular Disorders 2020 20:39

    Content type: Research article

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  9. Patients with cancer admitted for an acute coronary syndrome (ACS) and/or percutaneous coronary intervention (PCI) represent a growing and high-risk population. The influence of co-existing cancer on mortality...

    Authors: Vincent Roule, Laurine Verdier, Katrien Blanchart, Pierre Ardouin, Adrien Lemaitre, Mathieu Bignon, Rémi Sabatier, Joachim Alexandre and Farzin Beygui

    Citation: BMC Cardiovascular Disorders 2020 20:38

    Content type: Research article

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  10. The combined effects of diabetes mellitus (DM), admission plasma glucose (APG), and glycated hemoglobin (HbA1c) levels on predicting long-term clinical outcomes in patients with ST-segment elevation myocardial...

    Authors: Yan Li, Xiaowen Li, Yinhua Zhang, Leimin Zhang, Qingqing Wu, Zhaorun Bai, Jin Si, Xuebing Zuo, Ning Shi, Jing Li and Xi Chu

    Citation: BMC Cardiovascular Disorders 2020 20:36

    Content type: Research article

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  11. Although, in-part through an impact on left ventricular mass (LVM), resistin (an adipokine) may contribute to heart failure, whether this is explained by the adverse effects of resistin on aortic stiffness and...

    Authors: Glenda Norman, Gavin R. Norton, Vernice Peterson, Monica Gomes, Carlos D. Libhaber, Pinhas Sareli and Angela J. Woodiwiss

    Citation: BMC Cardiovascular Disorders 2020 20:35

    Content type: Research article

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  12. Aortic stenosis (AS) causes left ventricular (LV) pressure overload, leading to adverse LV remodeling and dysfunction. Identifying early subclinical markers of LV dysfunction in patients with significant AS is...

    Authors: Xiaojun Bi, Darwin F. Yeung, Husam M. Salah, Maria C. Arciniegas Calle, Jeremy J. Thaden, Lara F. Nhola, Hartzell V. Schaff, Sorin V. Pislaru, Patricia A. Pellikka, Alberto Pochettino, Kevin L. Greason, Vuyisile T. Nkomo and Hector R. Villarraga

    Citation: BMC Cardiovascular Disorders 2020 20:33

    Content type: Research article

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  13. Atrial fibrillation with symptomatic bradycardia, higher grade atrioventricular block, and sinus node disease are all common indications for permanent pacemaker implantation. The most frequent causes of sinus ...

    Authors: Jörg Reifart, Marlene Tschernatsch, Christian W. Hamm, Johannes Sperzel and Andreas Hain

    Citation: BMC Cardiovascular Disorders 2020 20:30

    Content type: Case report

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  14. The Starr-Edwards ball valve prosthesis was successfully introduced in 1961–62 and largely used for aortic and mitral valve replacement. Even if Starr-Edwards valves have been widely replaced in clinical pract...

    Authors: Andrea Ponsiglione, Gianrico Spagnuolo, Gabriella Spagnuolo, Arnaldo Stanzione, Carmela Nappi, Serena Dell’Aversana, Antonio Spagnuolo, Alberto Cuocolo and Massimo Imbriaco

    Citation: BMC Cardiovascular Disorders 2020 20:37

    Content type: Case report

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  15. The gut microbiome plays an important role in various cardiovascular diseases, such as atherosclerosis and hypertension, which are associated with abdominal aortic aneurysms (AAAs).

    Authors: Jiahe Xie, Weiling Lu, Lintao Zhong, Yuhua Hu, Qingrui Li, Rongming Ding, Zhonggao Zhong, Ziyou Liu, Hai Xiao, Dongming Xie, Guofu Zheng, Bo Ye, Yiming Zhong and Zuheng Liu

    Citation: BMC Cardiovascular Disorders 2020 20:32

    Content type: Research article

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  16. Evidence-based recommendations about anticoagulation in acute type B aortic dissection (TBAD) are completely missing, but there is a diffuse conviction that it could prevent the healing process of the dissecte...

    Authors: Pier Paolo Bocchino, Ovidio De Filippo, Francesco Piroli, Paolo Scacciatella, Massimo Imazio, Fabrizio D’Ascenzo and Gaetano Maria De Ferrari

    Citation: BMC Cardiovascular Disorders 2020 20:29

    Content type: Case report

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  17. TAB2 is an activator of MAP 3 K7/TAK1, which is required for the IL-1 induced signal pathway. Microdeletions encompassing TAB2 have been detected in various patients with congenital heart defects (CHD), indicatin...

    Authors: Jia Chen, Huizhen Yuan, Kang Xie, Xinrong Wang, Linglong Tan, Yongyi Zou, Yan Yang, Lu Pan, Junfang Xiao, Ge Chen and Yanqiu Liu

    Citation: BMC Cardiovascular Disorders 2020 20:27

    Content type: Case report

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  18. Sarcoidosis is a systemic granulomatous disease that may affect the myocardium. This study evaluated the diagnostic and prognostic value of 2-dimensional speckle tracking echocardiography in cardiac sarcoidosi...

    Authors: Cristina Di Stefano, Giulia Bruno, Maria C. Arciniegas Calle, Gayatri A. Acharya, Lynn M. Fussner, Patompong Ungprasert, Leslie T. Cooper Jr, Lori A. Blauwet, Jay H. Ryu, Patricia A. Pellikka, Eva M. Carmona Porquera and Hector R. Villarraga

    Citation: BMC Cardiovascular Disorders 2020 20:21

    Content type: Research article

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  19. Acute heart failure is a rapid onset of new or worsening of signs and symptoms of heart failure that requires hospitalization or a visit to the emergency department. The aim of this study was to evaluate treat...

    Authors: Mulubirhan Tirfe, Teshome Nedi, Desalew Mekonnen and Alemseged Beyene Berha

    Citation: BMC Cardiovascular Disorders 2020 20:16

    Content type: Research article

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  20. Both acute myocardial infarction and acute pulmonary embolism are distinct medical urgencies while they may conincide. Leriche’s syndrome is a relatively rare aortoiliac occlusive disease characterized by clau...

    Authors: Xuanqi An, Rui Fu, Zhihui Zhao, Xinhai Ni, Changming Xiong, Xiansheng Cheng and Zhihong Liu

    Citation: BMC Cardiovascular Disorders 2020 20:26

    Content type: Case report

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  21. Most reported cases of right anomalous coronary artery from the opposite sinus (R-ACAOS) have benign clinical outcomes. However, patients with left ACAOS (L-ACAOS) and some of the patients with R-ACAOS are mor...

    Authors: Kai-yue Diao, Qin Zhao, Yue Gao, Ke Shi, Min Ma, Hua-yan Xu, Ying-kun Guo and Zhi-gang Yang

    Citation: BMC Cardiovascular Disorders 2020 20:25

    Content type: Research article

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  22. Longitudinal stent deformation (LSD) is an infrequent complication of percutaneous coronary intervention (PCI), and it may lead to catastrophic clinical outcomes. However, reports of cardiac adverse events ass...

    Authors: Daoyuan Si, Yaliang Tong, Bo Yu, Yuquan He and Guohui Liu

    Citation: BMC Cardiovascular Disorders 2020 20:24

    Content type: Case report

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  23. Cardiorenal syndrome (CRS) is a group of pathophysiological disorders affecting heart and kidneys.

    Authors: E. Hryniewiecka, T. Hryniewiecki, J. Różański, T. Pilecki, R. Zagożdżon, T. Orłowski, M. Gołębiowski, L. Pączek, K. Mucha and B. Foroncewicz

    Citation: BMC Cardiovascular Disorders 2020 20:20

    Content type: Case report

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  24. Patients with acute coronary syndrome (ACS) who present to hospitals without interventional facilities frequently require transfer to another hospital equipped with a cardiac catheterization laboratory. This r...

    Authors: Michał Czapla, Dorota Zyśko, Tom Quinn and Piotr Karniej

    Citation: BMC Cardiovascular Disorders 2020 20:19

    Content type: Research article

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  25. Radiofrequency catheter ablation is an established procedure with a high success rate for treating Wolff–Parkinson–White (WPW) syndrome. Rare complications post-ablation may nonetheless occur particularly asso...

    Authors: Mei-fang Zheng, Zhen Wang and Zheng-yu Bao

    Citation: BMC Cardiovascular Disorders 2020 20:18

    Content type: Case report

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  26. Extracorporeal cardiopulmonary resuscitation (ECPR) can be associated with increased survival and neurologic benefits in selected patients with out-of-hospital cardiac arrest (OHCA). However, there remains ins...

    Authors: Kei Hayashida, Takahiro Kinoshita, Kazuma Yamakawa, Santiago J. Miyara, Lance B. Becker and Satoshi Fujimi

    Citation: BMC Cardiovascular Disorders 2020 20:23

    Content type: Correspondence

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  27. It has been reported that oral anticoagulation (OAC) is underused among Chinese patients with non-valvular atrial fibrillation (NVAF). Non-vitamin K antagonist oral anticoagulants (NOAC) have been recommended ...

    Authors: Ting Liu, Hui-li Yang, Lan Gu, Jie Hui, Ojo Omorogieva, Meng-xiao Ren and Xiao-hua Wang

    Citation: BMC Cardiovascular Disorders 2020 20:22

    Content type: Research article

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  28. Retrograde type A aortic dissection (RTAD) is a fatal aortic disease secondary to descending aortic dissection, and might be misdiagnosed due to its atypical symptoms lead to catastrophic outcomes.

    Authors: Yongle Ruan, Zhiwei Wang, Zhiyong Wu, Wei Ren, Zongli Ren, Anfeng Yu and Mohamed Rahouma

    Citation: BMC Cardiovascular Disorders 2020 20:17

    Content type: Case report

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  29. Platelets in patients with type 2 diabetes mellitus (DM2) are characterized by increased activation and aggregation, which tends to be associated with a high morbidity and mortality due to cardiovascular disea...

    Authors: Ai-ming Zhou, Yi-jia Xiang, En-qian Liu, Chang-hong Cai, Yong-hui Wu, Le-bing Yang and Chun-lai Zeng

    Citation: BMC Cardiovascular Disorders 2020 20:15

    Content type: Research article

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  30. This study aims to evaluate the ADL(activity of daily living) of patients with acute cerebral infarction through BI scoring, in order to observe its predictive value in the prognosis of these patients.

    Authors: Qun-Xi Li, Xiao-Jing Zhao, Yan Wang, Da-Li Wang, Jiang Zhang, Tie-Jun Liu, Yan-Bo Peng, Hai-Yan Fan and Fu-Xia Zheng

    Citation: BMC Cardiovascular Disorders 2020 20:14

    Content type: Research article

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  31. Liver disorders may be associated with normal pulmonary hemodynamic, hepatopulmonary syndrome (HPS), or portopulmonary hypertension (POPH). In this study, we aimed to investigate the effect of the severity of ...

    Authors: Ali Sepehrinezhad, Amirreza Dehghanian, Ali Rafati and Farzaneh Ketabchi

    Citation: BMC Cardiovascular Disorders 2020 20:13

    Content type: Research article

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  32. End-stage renal disease (ESRD) patients are at high cardiovascular risk, and myocardial fibrosis (MF) accounts for most of their cardiac events. The purpose of this study is to investigate the prognostic value...

    Authors: Hua-yan Xu, Zhi-gang Yang, Yi Zhang, Wan-lin Peng, Chun-chao Xia, Zhen-lin Li, Yong He, Rong Xu, Li Rao, Ying Peng, Yu-ming Li, Hong-ling Gao and Ying-kun Guo

    Citation: BMC Cardiovascular Disorders 2020 20:12

    Content type: Research article

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  33. Perioperative bleeding during cardiac surgery are known to make patients susceptible to adverse outcomes and several bleeding classifications have been developed to stratify the severity of bleeding events. Fu...

    Authors: Ziwei Xi, Yanan Gao, Zhenxian Yan, Yu-Jie Zhou and Wei Liu

    Citation: BMC Cardiovascular Disorders 2020 20:3

    Content type: Research article

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  34. This study investigated the value of layer-specific strain analysis by two-dimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in mainten...

    Authors: Chang Liu, Zi-Ning Yan, Li Fan, Jun Huang, Dan Shen and Xiang-Ting Song

    Citation: BMC Cardiovascular Disorders 2020 20:126

    Content type: Research article

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  35. Postcardiotomy cardiogenic shock (PCS) that is refractory to inotropic support remains a major concern in cardiac surgery and is almost universally fatal unless treated with mechanical support. While reported ...

    Authors: Mariusz Kowalewski, Giuseppe Maria Raffa, Kamil Zieliński, Musab Alanazi, Martijn Gilbers, Sam Heuts, Ehsan Natour, Elham Bidar, Rick Schreurs, Thijs Delnoij, Rob Driessen, Jan-Willem Sels, Marcel van de Poll, Paul Roekaerts, Paolo Meani, Jos Maessen…

    Citation: BMC Cardiovascular Disorders 2020 20:10

    Content type: Research article

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  36. Inflammatory reaction is an essential factor in the occurrence, development and prognosis of femoropopliteal disease (FPD). The ratio of platelets to lymphocytes (PLR) is a new indicator reflecting platelet ag...

    Authors: Yanhua Zhen, Zhihui Chang, Zhaoyu Liu and Jiahe Zheng

    Citation: BMC Cardiovascular Disorders 2020 20:9

    Content type: Research article

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  37. Ischemic cardiomyopathy is a high-cost, resource-intensive public health burden that is associated with a 1-year mortality rate of about 16% in western population. Different in patient ethnicity and pattern of...

    Authors: Nattawut Wongpraparut, Sarawut Siwamogsatham, Tomorn Thongsri, Pornchai Ngamjanyaporn, Arintaya Phrommintikul, Kompoj Jirajarus, Tarinee Tangcharoen, Kid Bhumimuang, Pinij Kaewsuwanna, Rungroj Krittayaphong, Rungtiwa Pongakasira and Harvey D. White

    Citation: BMC Cardiovascular Disorders 2020 20:8

    Content type: Research article

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  38. Previous clinical studies have suggested that trimethylamine-N-oxide (TMAO) could contribute to the development of atherosclerosis cardiovascular disease. However, the synthetic analysis in coronary heart dise...

    Authors: Miao-En Yao, Peng-Da Liao, Xu-Jie Zhao and Lei Wang

    Citation: BMC Cardiovascular Disorders 2020 20:7

    Content type: Research article

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  39. Kidney transplant patients suffer from vascular abnormalities and high cardiovascular event rates, despite initial improvements post-transplantation. The nature of the progression of vascular abnormalities in ...

    Authors: Joey Junarta, Nina Hojs, Robin Ramphul, Racquel Lowe-Jones, Juan C. Kaski and Debasish Banerjee

    Citation: BMC Cardiovascular Disorders 2020 20:6

    Content type: Research article

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  40. Left ventricular pseudoaneurysm is a very rare complication following acute myocardial infarction, which results from a free wall rupture. Hemopericardium and cardiac tamponade caused by rupture of the free wa...

    Authors: Xin Li, Yu Wang, Dong Wang, Chaohui Lai and Chenxin Wang

    Citation: BMC Cardiovascular Disorders 2020 20:5

    Content type: Case report

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  41. Preclinical studies indicate iron deficiency (ID) plays an important role in cardiac remodelling. However, the relationship between ID and cardiac remodelling remains unknown in clinical setting. This retrospe...

    Authors: Yan Chen, Jing Wan, Haidan Xia, Ya Li, Yufeng Xu, Haiyan Lin and Hassah Iftikhar

    Citation: BMC Cardiovascular Disorders 2020 20:4

    Content type: Research article

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  42. While rheumatic mitral stenosis has been effectively treated percutaneously for more than 20 years, mitral and tricuspid regurgitation treatment appear as a contemporary unmet need. The advent of transcatheter...

    Authors: Pavel Overtchouk, Nicolo Piazza, Juan Granada, Osama Soliman, Bernard Prendergast and Thomas Modine

    Citation: BMC Cardiovascular Disorders 2020 20:1

    Content type: Review

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  43. Chymase is the major angiotensin II (Ang II)-forming enzyme in cardiovascular tissue, with an important role in atrial remodeling. This study aimed to examine the association between chymase 1 gene (CMA1) polymor...

    Authors: Dongchen Zhou, Yuewei Chen, Jiaxin Wu, Jiabo Shen, Yushan Shang, Liangrong Zheng and Xudong Xie

    Citation: BMC Cardiovascular Disorders 2019 19:321

    Content type: Research article

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  44. A number of published literature has reported that, physiologically, heart rate variability (HRV) in patients with postural orthostatic tachycardia syndrome (POTS) to be greatly confounded by age, sex, race, p...

    Authors: Joel Swai, Zixuan Hu, Xiexiong Zhao, Tibera Rugambwa and Gui Ming

    Citation: BMC Cardiovascular Disorders 2019 19:320

    Content type: Research article

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  45. Serum immunoglobulins (Igs) play a critical role in modulating the immune response by neutralizing pathogens, although little is known about the effect of Igs in development of atherosclerotic cardiovascular d...

    Authors: Dee Lin, Mary Barna Bridgeman and Luigi Brunetti

    Citation: BMC Cardiovascular Disorders 2019 19:319

    Content type: Research article

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  46. Ticagrelor and clopidogrel, P2Y12 receptor antagonists, can prevent thrombotic events and are used to treat cardiovascular diseases such as acute coronary syndrome and chronic obstructive pulmonary disease, in wh...

    Authors: Zhuyin Jia, Yiwei Huang, Xiaojun Ji, Jiaju Sun and Guosheng Fu

    Citation: BMC Cardiovascular Disorders 2019 19:318

    Content type: Research article

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  47. Non-cardiac surgery for hypertrophic obstructive cardiomyopathy (HOCM) is considered to require meticulous perioperative care. β-blockers are considered the first-line drugs for patients with HOCM, and they pl...

    Authors: Yoichi Imori, Hitoshi Takano, Hiroshi Mase, Junya Matsuda, Hideto Sangen, Yuki Izumi, Yukichi Tokita, Takeshi Yamamoto and Wataru Shimizu

    Citation: BMC Cardiovascular Disorders 2019 19:316

    Content type: Research article

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  48. Transesophageal echocardiography may be used to assess pulmonary veins for atrial fibrillation ablation. No study focused on the role of transthoracic echocardiography (TTE) in evaluating the diameter and anat...

    Authors: Qing-Qing Dong, Wen-Yi Yang, Ya-Ping Sun, Qian Zhang, Guang Chu, Gen-Qing Zhou, Gang Chen, Song-Wen Chen, Shao-Wen Liu and Fang Wang

    Citation: BMC Cardiovascular Disorders 2019 19:315

    Content type: Research article

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