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  1. Genetic variants near/within the ALDH2 gene encoding the mitochondrial aldehyde dehydrogenase 2 have been associated with blood pressure and hypertension in several case–control association studies in East Asian ...

    Authors: Yi-Cheng Chang, Yen-Feng Chiu, I-Te Lee, Low-Tone Ho, Yi-Jen Hung, Chao A Hsiung, Thomas Quertermous, Timothy Donlon, Wei-Jei Lee, Po-Chu Lee, Che-Hong Chen, Daria Mochly-Rosen and Lee-Ming Chuang
    Citation: BMC Cardiovascular Disorders 2012 12:58
    Content type: Research article Published on:

  2. The data are inconsistent regarding whether extreme N-terminal fragment pro-B-type natriuretic peptide (NT pro-BNP) levels are associated with impaired renal function. Furthermore, the relationship between ext...

    Authors: Hua Cui, Guoliang Huo, Lin Liu, Li Fan, Ping Ye, Jian Cao, Yongyi Bai, Fan Wang and Yixin Hu
    Citation: BMC Cardiovascular Disorders 2012 12:57
    Content type: Research article Published on:

  3. Health promotion is a key component for primary prevention of cardiovascular disease (CVD). This study evaluated the impact of healthy lifestyle promotion campaigns on CVD risk factors (CVDRF) in the general p...

    Authors: Quang Ngoc Nguyen, Son Thai Pham, Viet Lan Nguyen, Lars Weinehall, Stig Wall, Ruth Bonita and Peter Byass
    Citation: BMC Cardiovascular Disorders 2012 12:56
    Content type: Research article Published on:

  4. p21-activated kinase (PAK) has been implicated in the inflammatory activation of endothelial cells by disturbed fluid shear stress, which is the initiating stimulus in atherosclerosis. The study addresses whet...

    Authors: K A Jhaveri, P Debnath, J Chernoff, J Sanders and M A Schwartz
    Citation: BMC Cardiovascular Disorders 2012 12:55
    Content type: Research article Published on:

  5. The present study was conducted to assess the nature of sympathovagal imbalance (SVI) in prehypertensives by short-term analysis of heart rate variability (HRV) to understand the alteration in autonomic modula...

    Authors: Gopal Krushna Pal, Adithan Chandrasekaran, Ananthanarayanan Palghat Hariharan, Tarun Kumar Dutta, Pravati Pal, Nivedita Nanda and Lalitha Venugopal
    Citation: BMC Cardiovascular Disorders 2012 12:54
    Content type: Research article Published on:

  6. To evaluate the frequency of positive coronary arteries calcium (CAC) scores in a unique population of asymptomatic first degree relatives (FDRs) of patients with angiographically confirmed early onset of coro...

    Authors: Catalin Taraboanta, Cameron J Hague, GB John Mancini, Bruce B Forster and Jiri Frohlich
    Citation: BMC Cardiovascular Disorders 2012 12:53
    Content type: Research article Published on:

  7. The impact of serum uric acid (SUA) on arteries of hypertensive subjects remains to be fully established. This study investigated the relationship between SUA and carotid structural and hemodynamic parameters ...

    Authors: José Alexandre Addeo Cipolli, Maria Carolina Ferreira-Sae, Rafael Prado Martins, José Alexandre Pio-Magalhães, Vera Regina Bellinazzi, José Roberto Matos-Souza and Wilson Nadruz Junior
    Citation: BMC Cardiovascular Disorders 2012 12:52
    Content type: Research article Published on:

  8. Studies have demonstrated that inflammation has a key role in the pathogenesis of atherosclerosis due to the abnormal gene expressions of multiple cytokines. We established an accurate and precise method to ob...

    Authors: Xingwang Jia, Haiyue Ju, Li Yang and Yaping Tian
    Citation: BMC Cardiovascular Disorders 2012 12:51
    Content type: Research article Published on:

  9. In recent years, catheter ablation has increasingly been used for ablation of idiopathic premature ventricular complexes (PVCs) or ventricular tachycardias (IVTs). However, the mapping and catheter ablation of...

    Authors: Li Yue-Chun, Zhang Wen-Wu, Zhou Na-Dan, Zhang Teng, Wang Pin-Xiao, Ge Bei, Li Jia, Ji Kang-Ting and Lin Jia-Feng
    Citation: BMC Cardiovascular Disorders 2012 12:32
    Content type: Research article Published on:

  10. Cardiac rehabilitation is very important for the recovery and the secondary prevention of cardiovascular disease, and one of its main strategies is to increase the level of physical activity. Internet and mobi...

    Authors: Konstantinos Antypas and Silje C Wangberg
    Citation: BMC Cardiovascular Disorders 2012 12:50
    Content type: Study protocol Published on:

  11. As the management of patients treated with anticoagulants and antiplatelet drugs entails balancing coagulation levels, we evaluated the net clinical benefit of warfarin and aspirin on stroke in a large cohort ...

    Authors: Laurent Azoulay, Sophie Dell’Aniello, Teresa A Simon, David Langleben, Christel Renoux and Samy Suissa
    Citation: BMC Cardiovascular Disorders 2012 12:49
    Content type: Research article Published on:

  12. Large artery stiffening and wave reflections are independent predictors of adverse events. To date, their assessment has been limited to specialised techniques and settings. A new, more practical method allowi...

    Authors: David Nunan, Siegfried Wassertheurer, Daniel Lasserson, Bernhard Hametner, Susannah Fleming, Alison Ward and Carl Heneghan
    Citation: BMC Cardiovascular Disorders 2012 12:48
    Content type: Research article Published on:

  13. Cardiovascular disease (CVD) is the leading cause of death worldwide. Secondary prevention is essential, but participation rates for cardiac rehabilitation are low. Furthermore, current programmes do not accom...

    Authors: Chantal J Leemrijse, Liset van Dijk, Harald T Jørstad, Ron J G Peters and Cindy Veenhof
    Citation: BMC Cardiovascular Disorders 2012 12:47
    Content type: Study protocol Published on:

  14. Left ventricular (LV) rotation is increasingly examined in those with heart disease. The available evidence measuring LV rotation in those with heart diseases has not been systematically reviewed.

    Authors: Aaron A Phillips, Anita T Cote, Shannon SD Bredin and Darren ER Warburton
    Citation: BMC Cardiovascular Disorders 2012 12:46
    Content type: Research article Published on:

  15. Spain, a Mediterranean country with relatively low rates of coronary heart disease, has a high prevalence of traditional cardiovascular risk factors and is experiencing a severe epidemic of overweight/obesity....

    Authors: José A Casasnovas, Victor Alcaide, Fernando Civeira, Eliseo Guallar, Borja Ibañez, Jesús Jiménez Borreguero, Martin Laclaustra, Montserrat León, José Luis Peñalvo, José M Ordovás, Miguel Pocovi, Ginés Sanz and Valentín Fuster
    Citation: BMC Cardiovascular Disorders 2012 12:45
    Content type: Study protocol Published on:

  16. Fragmented QRS (fQRS) complexes are novel electrocardiographic signals, which reflect myocardial conduction delays in patients with coronary artery disease (CAD). The importance of fQRS complexes in identifyin...

    Authors: Rong Guo, Yuanmin Li, Yawei Xu, Kai Tang and Weimin Li
    Citation: BMC Cardiovascular Disorders 2012 12:44
    Content type: Research article Published on:

  17. In response to the short-term negative inotropic and chronotropic effects of β-blockers, heart failure (HF) guidelines recommend initiating β-blockers at low dose with gradual uptitration as tolerated to doses...

    Authors: Larry A Allen, David J Magid, Chan Zeng, Pamela N Peterson, Christina L Clarke, Susan Shetterly, David W Brand and Frederick A Masoudi
    Citation: BMC Cardiovascular Disorders 2012 12:43
    Content type: Research article Published on:

  18. The purpose of the present study was to assess the trends in the use of ECV following published studies that had compared rhythm and rate control strategies on atrial fibrillation (AF), and the recommendations...

    Authors: Josep M Alegret, Xavier Viñolas, César Romero-Menor, Silvia Pons, Roger Villuendas, Naiara Calvo, Jordi Pérez-Rodon and Xavier Sabaté
    Citation: BMC Cardiovascular Disorders 2012 12:42
    Content type: Research article Published on:

  21. Fabry disease (FD) is a hereditary metabolic disorder caused by the partial or total inactivation of a lysosomal hydrolase, the enzyme α-galactosidase A (GLA). This inactivation is responsible for the storage ...

    Authors: Antonio Pisani, Massimo Imbriaco, Carmela Zizzo, Giuseppe Albeggiani, Paolo Colomba, Riccardo Alessandro, Francesco Iemolo and Giovanni Duro
    Citation: BMC Cardiovascular Disorders 2012 12:39
    Content type: Case report Published on:

  22. Inflammation processes are important participants in the pathophysiology of hypertension and cardiovascular diseases. The role of the alpha7 nicotinic acetylcholine receptor (α7nAChR) in inflammation has recen...

    Authors: Ji-Kuai Chen, Ting Zhao, Min Ni, Dong-Jie Li, Xia Tao and Fu-Ming Shen
    Citation: BMC Cardiovascular Disorders 2012 12:38
    Content type: Research article Published on:

  23. The present study was designed to evaluate the relationship between high-sensitivity C-reactive protein (hs-CRP) and arterial stiffness according to sex in patients with arterial hypertension.

    Authors: Manuel A Gomez-Marcos, Jose I Recio-Rodríguez, Maria C Patino-Alonso, Cristina Agudo-Conde, Leticia Gomez-Sanchez, Emiliano Rodriguez-Sanchez, Marta Gomez-Sanchez, Vicente Martinez-Vizcaino and Luis Garcia-Ortiz
    Citation: BMC Cardiovascular Disorders 2012 12:37
    Content type: Research article Published on:

  24. Involving stakeholders and consumers throughout the content and study design ensures interventions are engaging and relevant for end-users. The aim of this paper is to present the content development process f...

    Authors: Leila Pfaeffli, Ralph Maddison, Robyn Whittaker, Ralph Stewart, Andrew Kerr, Yannan Jiang, Geoff Kira, Karen Carter and Lance Dalleck
    Citation: BMC Cardiovascular Disorders 2012 12:36
    Content type: Research article Published on:

  25. YKL-40, a proposed marker of inflammation and endothelial dysfunction, is associated with atherosclerosis and an increased cardiovascular mortality in the general population. However, the relationship between ...

    Authors: Wei-hong Ma, Xiu-ling Wang, Yi-meng Du, Yi-biao Wang, Yan Zhang, De-e Wei, Lin-lin Guo and Pei-Li Bu
    Citation: BMC Cardiovascular Disorders 2012 12:35
    Content type: Research article Published on:

  26. Considerable proportion of patients does not respond to the cardiac resynchronization therapy (CRT). This study investigated clinical relevance of left ventricular electrode local electrogram delay from the be...

    Authors: Rostislav Polasek, Pavel Kucera, Pavel Nedbal, Tomas Roubicek, Tomas Belza, Jana Hanuliakova, David Horak, Dan Wichterle and Josef Kautzner
    Citation: BMC Cardiovascular Disorders 2012 12:34
    Content type: Research article Published on:

  27. There is no more effective intervention for secondary prevention of coronary heart disease than smoking cessation. Yet, evidence about the (cost-)effectiveness of smoking cessation treatment methods for cardia...

    Authors: Nadine Berndt, Catherine Bolman, Lilian Lechner, Aart Mudde, Freek WA Verheugt and Hein de Vries
    Citation: BMC Cardiovascular Disorders 2012 12:33
    Content type: Study protocol Published on:

  28. Older age, as a factor we cannot affect, is consistently one of the main negative prognostic values in patients with acute myocardial infarction. One of the most powerful factors that improves outcomes in pati...

    Authors: Petr Kala, Jan Kanovsky, Richard Rokyta, Michal Smid, Jan Pospisil, Jiri Knot, Filip Rohac, Martin Poloczek, Tomas Ondrus, Maria Holicka, Jindrich Spinar, Jiri Jarkovsky and Ladislav Dusek
    Citation: BMC Cardiovascular Disorders 2012 12:31
    Content type: Research article Published on:

  29. Hypertension is a common comorbidity in patients with heart failure and may contribute to development and course of disease, but the importance of a history of hypertension in patients with prevalent heart fai...

    Authors: Charlotte Andersson, Gunnar H Gislason, Peter Weeke, Jesper Kjaergaard, Christian Hassager, Dilek Akkan, Jacob E Møller, Lars Køber and Christian Torp-Pedersen
    Citation: BMC Cardiovascular Disorders 2012 12:30
    Content type: Research article Published on:

  30. The arterial wall possesses several functional and structural properties that define arterial health. Once they become impaired, cardiovascular risk increases. We aimed to ascertain the pattern of correlations...

    Authors: Mojca Lunder, Miodrag Janic, Natasa Kejzar and Miso Sabovic
    Citation: BMC Cardiovascular Disorders 2012 12:29
    Content type: Research article Published on:

  31. Cardiac tamponade is a rare but severe complication of pericardial effusion with a poor prognosis. Prompt diagnosis using transthoracic echocardiography allows guiding initial therapeutic management. Although ...

    Authors: Anne Cypierre, Francis Pesteil, Claude Cassat, François Parraf, Rémy Bellier, Lionel Ursulet, Claire Eveno, Philippe Vignon and Bruno François
    Citation: BMC Cardiovascular Disorders 2012 12:28
    Content type: Case report Published on:

  32. Predicting response to cardiac resynchronization therapy (CRT) remains a challenge. We evaluated the role of baseline QRS pattern to predict response in terms of improvement in biventricular ejection fraction ...

    Authors: Giulia Domenichini, Haran Burri, Cinzia Valzania, Gilberto Gavaruzzi, Francesco Fallani, Mauro Biffi, Henri Sunthorn, Igor Diemberger, Cristian Martignani, Huberdine Foulkes, Eric Fleury and Giuseppe Boriani
    Citation: BMC Cardiovascular Disorders 2012 12:27
    Content type: Research article Published on:

  33. Hypertension is one of the leading causes of cardiovascular disease (CVD). A range of antihypertensive drugs exists, and their prices vary widely mainly due to patent rights. The objective of this study was to...

    Authors: Torbjørn Wisløff, Randi M Selmer, Sigrun Halvorsen, Atle Fretheim, Ole F Norheim and Ivar Sønbø Kristiansen
    Citation: BMC Cardiovascular Disorders 2012 12:26
    Content type: Research article Published on:

  34. The risk of experiencing an acute myocardial infarction (AMI) increases with age and Canada's population is aging. The objective of this analysis was to examine trends in the AMI hospitalization rate in Canada...

    Authors: Nigel SB Rawson, Rong Chu, Afisi S Ismaila and Jorge Alfonso Ross Terres
    Citation: BMC Cardiovascular Disorders 2012 12:25
    Content type: Research article Published on:

  35. Accelerated atherosclerosis is the main cause of late aortocoronary vein graft failure. We aimed to develop a large animal model for the study of pathogenesis and treatment of vein graft atherosclerosis.

    Authors: Troels Thim, Mette Kallestrup Hagensen, Arne Hørlyck, Ludovic Drouet, William P Paaske, Hans Erik Bøtker and Erling Falk
    Citation: BMC Cardiovascular Disorders 2012 12:24
    Content type: Research article Published on:

  36. Maternal mortality in South Africa is rising, and heart conditions currently account for 41 per cent of indirect causes of deaths. Little is known about the burden of heart disease in pregnant South Africans.

    Authors: David A Watkins, Motshedisi Sebitloane, Mark E Engel and Bongani M Mayosi
    Citation: BMC Cardiovascular Disorders 2012 12:23
    Content type: Research article Published on:

  37. Cigarette exposure increases brain oxidative stress. The literature showed that increased brain oxidative stress affects cardiovascular regulation. However, no previous study investigated the involvement of br...

    Authors: Vitor E Valenti, Luiz Carlos de Abreu, Monica A Sato, Celso Ferreira, Fernando Adami, Fernando LA Fonseca, Valdelias Xavier, Moacir Godoy, Carlos B Monteiro, Luiz Carlos M Vanderlei and Paulo HN Saldiva
    Citation: BMC Cardiovascular Disorders 2012 12:22
    Content type: Research article Published on:

  38. Atrioventricular block (AVB) is a well-reported complication after closure of perimembranous ventricular septal defects (VSDs). To report the occurrence of AVB either during or following closure of perimembran...

    Authors: Qiang Chen, Hua Cao, Gui-Can Zhang, Liang-Wan Chen, Qian-Zhen Li and Zhi-Huang Qiu
    Citation: BMC Cardiovascular Disorders 2012 12:21
    Content type: Research article Published on:

  39. Studies from Sweden have reported association between immigrant status and incidence of cardiovascular diseases. The nature of this relationship is unclear. We investigated the relationship between immigrant s...

    Authors: Yan Borné, Gunnar Engström, Birgitta Essén and Bo Hedblad
    Citation: BMC Cardiovascular Disorders 2012 12:20
    Content type: Research article Published on:

  40. We investigated the association between heart rate and its variability with the parameters that assess vascular, renal and cardiac target organ damage.

    Authors: Ángel García-García, Manuel A Gómez-Marcos, José I Recio-Rodríguez, Maria C Patino-Alonso, Emiliano Rodríguez-Sánchez, Cristina Agudo-Conde and Luis García-Ortiz
    Citation: BMC Cardiovascular Disorders 2012 12:19
    Content type: Research article Published on:

  41. Data on clinical outcomes among patients treated with the zotarolimus-eluting Endeavor™ stent versus the sirolimus-eluting Cypher™ stent favor the sirolimus-eluting stent. However, a separate comparison of cli...

    Authors: Troels Thim, Michael Maeng, Jens Flensted Lassen, Anne Kaltoft, Lisette Okkels Jensen, Jan Ravkilde, Per Thayssen, Søren Galatius, Evald Høj Christiansen, Thomas Engstrøm, Morten Madsen, Leif Thuesen and Hans Henrik Tilsted
    Citation: BMC Cardiovascular Disorders 2012 12:18
    Content type: Research article Published on:

  42. Impact of minimized extracorporeal circulation (MECC) for coronary surgery on mortality remains controversial and gender significantly influence outcome.

    Authors: Michael Ried, Reinhard Kobuch, Leopold Rupprecht, Andreas Keyser, Michael Hilker, Christof Schmid and Claudius Diez
    Citation: BMC Cardiovascular Disorders 2012 12:17
    Content type: Research article Published on:

  43. Elevated serum bilirubin has been associated with reduced risk of cardiovascular disease (CVD). However, serum bilirubin is also related with several potential confounders related to CVD, such as obesity. Mend...

    Authors: Patrick F McArdle, Brian W Whitcomb, Keith Tanner, Braxton D Mitchell, Alan R Shuldiner and Afshin Parsa
    Citation: BMC Cardiovascular Disorders 2012 12:16
    Content type: Research article Published on:

  44. One of the most important risk factors for stroke is hypertension. A number of studies have attempted to identify the most effective anti-hypertensive therapeutic group for stroke prevention. Using an epidemio...

    Authors: Renata Papp, Albert Csaszar, Edit Paulik and Sandor Balogh
    Citation: BMC Cardiovascular Disorders 2012 12:15
    Content type: Research article Published on:

  45. Acute allograft rejection is a major cause of early mortality in the first year after heart transplantation in adults. Although endomyocardial biopsy (EMB) is not a perfect "gold standard" for a correct diagno...

    Authors: Lynn V Doering, Kathleen Hickey, David Pickham, Belinda Chen and Barbara J Drew
    Citation: BMC Cardiovascular Disorders 2012 12:14
    Content type: Study protocol Published on:

  46. Peak first derivative of femoral artery pressure (arterial dP/dtmax) derived from fluid-filled catheter remains questionable to assess left ventricular (LV) contractility during shock. The aim of this study was t...

    Authors: Philippe Morimont, Bernard Lambermont, Thomas Desaive, Nathalie Janssen, Geoffrey Chase and Vincent D'Orio
    Citation: BMC Cardiovascular Disorders 2012 12:13
    Content type: Research article Published on:

  47. In patients with non-valvular atrial fibrillation (NVAF) at high risk for stroke guidelines consistently recommend long-term oral anticoagulation (OAC) with a vitamin K antagonist. However recommendations rema...

    Authors: Bernhard Gerber, Georg Stussi, Thomas Rosemann and Oliver Senn
    Citation: BMC Cardiovascular Disorders 2012 12:12
    Content type: Research article Published on:

  48. Patients with systemic lupus erythematosus (SLE) have increased cardiovascular morbidity and mortality. Although autopsy studies have documented that the heart is affected in most SLE patients, clinical manife...

    Authors: Javad Kojuri, Mohammad ali Nazarinia, Mohammad Ghahartars, Yadollah Mahmoody, Gholam reza Rezaian and Lida Liaghat
    Citation: BMC Cardiovascular Disorders 2012 12:11
    Content type: Research article Published on:

  49. Atrial fibrillation is the most common type of arrhythmia after cardiac surgery. An increasing body of evidence demonstrates that oxidative stress plays a pivotal role in the pathophysiology of atrial fibrilla...

    Authors: Wan-Jie Gu, Zhen-Jie Wu, Peng-Fei Wang, Lynn Htet Htet Aung and Rui-Xing Yin
    Citation: BMC Cardiovascular Disorders 2012 12:10
    Content type: Research article Published on:

  50. Studies on the impact of time to treatment on myocardial infarct size have yielded conflicting results. In this study of ST-Elevation Myocardial Infarction (STEMI) treated with primary percutaneous coronary in...

    Authors: Tim Tödt, Eva Maret, Joakim Alfredsson, Magnus Janzon, Jan Engvall and Eva Swahn
    Citation: BMC Cardiovascular Disorders 2012 12:9
    Content type: Research article Published on:
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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