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  1. The purpose of the Finnish Cardiovascular Study (FINCAVAS) is to construct a risk profile – using genetic, haemodynamic and electrocardiographic (ECG) markers – of individuals at high risk of cardiovascular di...

    Authors: Tuomo Nieminen, Rami Lehtinen, Jari Viik, Terho Lehtimäki, Kari Niemelä, Kjell Nikus, Mari Niemi, Janne Kallio, Tiit Kööbi, Väinö Turjanmaa and Mika Kähönen
    Citation: BMC Cardiovascular Disorders 2006 6:9
  2. Gender influences the cardiac response to prolonged increases in workload, with differences at structural, functional, and molecular levels. However, it is unknown if post-ischemic function or metabolism of fe...

    Authors: Ramesh Saeedi, Richard B Wambolt, Hannah Parsons, Christine Antler, Hon S Leong, Angelica Keller, George A Dunaway, Kirill M Popov and Michael F Allard
    Citation: BMC Cardiovascular Disorders 2006 6:8
  3. A low ankle-brachial index (ABI) is associated with increased risk of coronary heart disease, stroke, and death. Regression model parameter estimates may be biased due to measurement error when the ABI is incl...

    Authors: Beth D Weatherley, Lloyd E Chambless, Gerardo Heiss, Diane J Catellier and Curtis R Ellison
    Citation: BMC Cardiovascular Disorders 2006 6:7
  4. Hyperlipidemia and hypertension are well-established risk factors for recurrent cardiovascular events among patients with ischemic heart disease (IHD). Despite national recommendations, concordance with guidel...

    Authors: P Michael Ho, Allan V Prochazka, David J Magid, Anne E Sales, Gary K Grunwald, Karl E Hammermeister and John S Rumsfeld
    Citation: BMC Cardiovascular Disorders 2006 6:6
  5. I have found an error in the Discussion section of my recent article [1]. While citing a prior work by Okura et al. [2], I incorrectly wrote that their weight-loss participants had "only a 2 percent reduction in ...

    Authors: Henry S Kahn
    Citation: BMC Cardiovascular Disorders 2006 6:5

    The original article was published in BMC Cardiovascular Disorders 2005 5:26

  6. Hypertension is a global problem and it is prevalent in Nigeria. Left ventricular hypertrophy is a major complication of hypertension with risk of sudden death and arrhythmias among others. Abnormal left ventr...

    Authors: Akinyemi Aje, Adewole A Adebiyi, Olulola O Oladapo, Adekola Dada, Okechukwu S Ogah, Dike B Ojji and Ayodele O Falase
    Citation: BMC Cardiovascular Disorders 2006 6:4
  7. Cigarette smoking is a strong risk factor for vascular disease and known to cause dysfunction of the endothelium. However, the molecular mechanisms involved are still not fully understood.

    Authors: Jin-Yan Zhang, Yong-Xiao Cao, Cang-Bao Xu and Lars Edvinsson
    Citation: BMC Cardiovascular Disorders 2006 6:3
  8. Skeletal muscle consists of type-I (slow-twitch) and type-II (fast-twitch) fibers, with proportions highly variable between individuals and mostly determined by genetic factors. Cross-sectional studies have as...

    Authors: Jouko Karjalainen, Heikki Tikkanen, Miika Hernelahti and Urho M Kujala
    Citation: BMC Cardiovascular Disorders 2006 6:2
  9. The occurrence of variations in the spectrum of cardiovascular disease between different regions of the world and ethnic groups have been the subject of great interest. This study report the 24-h variation of ...

    Authors: Carlos E D'Negri, Leonardo Nicola-Siri, Daniel E Vigo, Luis A Girotti and Daniel P Cardinali
    Citation: BMC Cardiovascular Disorders 2006 6:1
  10. Since its first description, Mönckeberg's sclerosis has only been related to arterial media calcification, being listed among the primary diseases of the vessels.

    Authors: Carlos Eduardo Barra Couri, Geruza Alves da Silva, José Antônio Baddini Martinez, Francisco de Assis Pereira and Francisco José Albuquerque de Paula
    Citation: BMC Cardiovascular Disorders 2005 5:34
  11. The increasing burden of cardiovascular diseases (CVD) in the ageing population of industrialized nations requires an intensive search for means of reducing this epidemic. In order to improve prevention, detec...

    Authors: Karin H Greiser, Alexander Kluttig, Barbara Schumann, Jan A Kors, Cees A Swenne, Oliver Kuss, Karl Werdan and Johannes Haerting
    Citation: BMC Cardiovascular Disorders 2005 5:33
  12. Microsomal transfer protein inhibitors (MTPi) have the potential to be used as a drug to lower plasma lipids, mainly plasma triglycerides (TG). However, studies with animal models have indicated that MTPi trea...

    Authors: Dimple Aggarwal, Kristy L West, Tosca L Zern, Sudeep Shrestha, Marcela Vergara-Jimenez and Maria Luz Fernandez
    Citation: BMC Cardiovascular Disorders 2005 5:30
  13. Accurate measurement of the QT interval is very important from a clinical and pharmaceutical drug safety screening perspective. Expert manual measurement is both imprecise and imperfectly reproducible, yet it ...

    Authors: Anthony Charles Hunt
    Citation: BMC Cardiovascular Disorders 2005 5:29
  14. Experimental studies support an important role for endothelial nitric oxide synthase (eNOS) in the regulation of angiogenesis. In humans, a common polymorphism exists in the eNOS gene that results in the conve...

    Authors: Nicolas Lamblin, François J Cuilleret, Nicole Helbecque, Jean Dallongeville, Jean-Marc Lablanche, Philippe Amouyel, Christophe Bauters and Eric Van Belle
    Citation: BMC Cardiovascular Disorders 2005 5:27
  15. Body mass index (BMI, kg/m2) may not be the best marker for estimating the risk of obesity-related disease. Consistent with physiologic observations, an alternative index uses waist circumference (WC) and fasting...

    Authors: Henry S Kahn
    Citation: BMC Cardiovascular Disorders 2005 5:26

    The Erratum to this article has been published in BMC Cardiovascular Disorders 2006 6:5

  16. The protective role of high-density lipoprotein (HDL) in the cardiovascular system is related to its role in the reverse transport of cholesterol from the arterial wall to the liver for subsequent excretion vi...

    Authors: Per-Arne Svensson, Mikael CO Englund, Magnus SC Snäckestrand, Daniel A Hägg, Bertil G Ohlsson, Veronika Stemme, Lillemor Mattsson-Hulten, Dag S Thelle, Björn Fagerberg, Olov Wiklund, Lena MS Carlsson and Björn Carlsson
    Citation: BMC Cardiovascular Disorders 2005 5:25
  17. In patients with acute stroke, increased body temperature is associated with large lesion volumes, high case fatality, and poor functional outcome. A 1°C increase in body temperature may double the odds of poo...

    Authors: Eric J van Breda, H Bart van der Worp, H Maarten A van Gemert, Ale Algra, L Jaap Kappelle, Jan van Gijn, Peter J Koudstaal and Diederik WJ Dippel
    Citation: BMC Cardiovascular Disorders 2005 5:24

    The Erratum to this article has been published in BMC Cardiovascular Disorders 2008 8:29

  18. Sirolimus-eluting stents (CYPHER stents) demonstrated remarkable efficacy in reducing restenosis rates in patients with coronary artery disease. There is a concern of sub-acute and late stent thrombosis. Tissu...

    Authors: Shengsi Zhu, Hema Viswambharan, Thusitha Gajanayake, Xiu-Fen Ming and Zhihong Yang
    Citation: BMC Cardiovascular Disorders 2005 5:22
  19. Regional disparities in medical care and outcomes with patients suffering from an acute coronary syndrome (ACS) have been reported and raise the need to a better understanding of links between treatment, care ...

    Authors: Alain Vanasse, Théophile Niyonsenga, Josiane Courteau, Jean-Pierre Grégoire, Abbas Hemiari, Julie Loslier and Goze Bénié
    Citation: BMC Cardiovascular Disorders 2005 5:21
  20. Natural history of paroxysmal atrial fibrillation (AF) is not very well documented. Clinical experience suggests that paroxysmal AF could progress to chronic AF with estimates ranging between 15 and 30% over a...

    Authors: Ana Ruigómez, Saga Johansson, Mari-Ann Wallander and Luis Alberto García Rodríguez
    Citation: BMC Cardiovascular Disorders 2005 5:20
  21. Aprotinin has been shown to be effective in reducing peri-operative blood loss and the need for re-operation due to continued bleeding in cardiac surgery. The lysine analogues tranexamic acid (TXA) and epsilon...

    Authors: Paul A Carless, Annette J Moxey, Barrie J Stokes and David A Henry
    Citation: BMC Cardiovascular Disorders 2005 5:19
  22. Increasing evidence suggests that ABPM more closely predicts target organ damage than does clinic measurement. Future guidelines may suggest ABPM as routine in the diagnosis and monitoring of hypertension. Thi...

    Authors: Linda Beckett and Marshall Godwin
    Citation: BMC Cardiovascular Disorders 2005 5:18
  23. Although much has been written about the influence of local opinion leaders on clinical practice, there have been few controlled studies of their effect, and almost none have attempted to change prescribing in...

    Authors: Sumit R Majumdar, Finlay A McAlister and Ross T Tsuyuki
    Citation: BMC Cardiovascular Disorders 2005 5:17
  24. Prior literature has shown that racial/ethnic minorities with hypertension may receive less aggressive treatment for their high blood pressure. However, to date there are few data available regarding the confo...

    Authors: LeRoi S Hicks, Shimon Shaykevich, David W Bates and John Z Ayanian
    Citation: BMC Cardiovascular Disorders 2005 5:16
  25. Awareness of the significance of peripheral arterial disease is increasing, but quantitative estimates of the ensuing burden and the impact of other risk factors remains limited. The objective of this study wa...

    Authors: Jaime Caro, Kristen Migliaccio-Walle, Khajak J Ishak and Irina Proskorovsky
    Citation: BMC Cardiovascular Disorders 2005 5:14
  26. Persistence is a key factor for long-term blood pressure control, which is of high prognostic importance for patients at increased cardiovascular risk. Here we present the results of a post-marketing survey in...

    Authors: Michel Burnier, Bernhard Hess, Peter Greminger and Bernard Waeber
    Citation: BMC Cardiovascular Disorders 2005 5:13
  27. Chronic inflammatory stimuli such as cytomegalovirus (CMV) infection and various genetic polymorphisms determining the inflammatory response are assumed to be important risk factors in atherosclerosis. We inve...

    Authors: Dietrich Rothenbacher, Hermann Brenner, Thomas Mertens, Michael M Hoffmann, Albrecht Hoffmeister and Wolfgang Koenig
    Citation: BMC Cardiovascular Disorders 2005 5:10
  28. Mycophenolate mofetil (MMF), the prodrug of mycophenolic acid (MPA), is a rationally designed immunosuppressive drug. The current study investigates the effect of MMF on key pattern of restenosis in a cascade ...

    Authors: Rainer Voisard, Sandra Viola, Verena Kaspar, Christian M Weber, Lutz von Müller, Regine Baur, Iris Gastrock-Balitsch and Vinzenz Hombach
    Citation: BMC Cardiovascular Disorders 2005 5:9
  29. The same mechanisms by which ultrasound enhances thrombolysis are described in connection with non-beneficial effects of ultrasound. The present safety study was therefore designed to explore effects of benefi...

    Authors: Göran K Olivecrona, Bjarne Madsen Härdig, Anders Roijer, Mattias Block, Edgars Grins, Hans W Persson, Leif Johansson and Bertil Olsson
    Citation: BMC Cardiovascular Disorders 2005 5:8
  30. Essential hypertension is a major public health concern worldwide where its prevalence accounts for various cerebrovascular diseases. A common molecular variant of angiotensinogen (AGT), the precursor of poten...

    Authors: Yee-How Say, King-Hwa Ling, Gnanasothie Duraisamy, Suzanne Isaac and Rozita Rosli
    Citation: BMC Cardiovascular Disorders 2005 5:7
  31. Acute myocardial infarction (MI) following anaphylaxis is rare, especially in subjects with normal coronary arteries. The exact pathogenetic mechanism of MI in anaphylaxis remains unclear.

    Authors: Aristofanis Gikas, George Lazaros and Kalliopi Kontou-Fili
    Citation: BMC Cardiovascular Disorders 2005 5:6
  32. Shorter time to treatment is associated with lower mortality in acute coronary syndromes (ACS). A previous (1994) survey showed substantial delays for acute myocardial infarction (AMI) in Ireland. The present ...

    Authors: Frank Doyle, Davida De La Harpe, Hannah McGee, Emer Shelley and Ronán Conroy
    Citation: BMC Cardiovascular Disorders 2005 5:5
  33. Lack of antihypertensive use among hypertensive individuals is a major public health problem. It remains unclear as to how much of this lack of treatment is because of failure to diagnose hypertension or failu...

    Authors: Nadia A Khan, Dennis Wardman and Norman RC Campbell
    Citation: BMC Cardiovascular Disorders 2005 5:4
  34. Persistent atrial fibrillation (AF) is difficult to treat. In the absence of class I or III antiarrhythmic drugs sinus rhythm is maintained in only 30% of patients during the first year after electrical cardio...

    Authors: Trudeke Van Noord, Harry JGM Crijns, Maarten P van den Berg, Dirk J Van Veldhuisen and Isabelle C Van Gelder
    Citation: BMC Cardiovascular Disorders 2005 5:3
  35. Although current evidence suggests that the spatial T wave axis captures important information about ventricular repolarization abnormalities, there are only a few and discordant epidemiologic studies addressi...

    Authors: Georgeta D Vaidean, Pentti M Rautaharju, Ronald J Prineas, Eric A Whitsel, Lloyd E Chambless, Aaron R Folsom, Wayne D Rosamond, Zhu-Ming Zhang, Richard S Crow and Gerardo Heiss
    Citation: BMC Cardiovascular Disorders 2005 5:2
  36. Despite heavy recent emphasis on blood pressure (BP) control, many patients fail to meet widely accepted goals. While access and adherence to therapy certainly play a role, another potential explanation is poo...

    Authors: Steven M Asch, Elizabeth A McGlynn, Liisa Hiatt, John Adams, Jennifer Hicks, Alison DeCristofaro, Roland Chen, Pablo LaPuerta and Eve A Kerr
    Citation: BMC Cardiovascular Disorders 2005 5:1
  37. To evaluate current treatment patterns for coronary artery revascularization in Canada and explore the potential impact of drug eluting stents (DES) on these treatment patterns.

    Authors: Michael T Halpern, Michael Lacey, Mary Ann Clark and Miguel A Valentin
    Citation: BMC Cardiovascular Disorders 2004 4:23
  38. Intra-aortic balloon counterpulsation (IABC) has an established role in the treatment of patients presenting with critical cardiac illnesses, including cardiogenic shock, refractory ischemia and for prophylaxi...

    Authors: Fahim H Jafary, Sohail A Khan, Haresh Kumar, Numaan F Malik, Khawar A Kazmi, Sajid Dhakam, Azam Shafquat, Aamir Hameed, Javed Tai and Najaf Nadeem
    Citation: BMC Cardiovascular Disorders 2004 4:22
  39. Coronary artery calcium score incrementally improves coronary risk prediction beyond that provided by conventional risk factors. Limited information is available regarding rates of progression of coronary calc...

    Authors: Judith Hsia, Afifa Klouj, Anjana Prasad, Jeremy Burt, Lucile L Adams-Campbell and Barbara V Howard
    Citation: BMC Cardiovascular Disorders 2004 4:21
  40. Certain conditions characterised by blood vessel occlusion or vascular spasm have been found to cluster together in epidemiological studies. However the biological causes for these associations remain controve...

    Authors: Frances MK Williams, Lynn F Cherkas, Tim D Spector and Alex J MacGregor
    Citation: BMC Cardiovascular Disorders 2004 4:20
  41. Warfarin therapy is effective for the prevention of stroke in patients with atrial fibrillation. However, warfarin therapy is underutilized even among ideal anticoagulation candidates. The purpose of this stud...

    Authors: Dawn M Bravata, Karen Rosenbeck, Sue Kancir and Lawrence M Brass
    Citation: BMC Cardiovascular Disorders 2004 4:18
  42. Plasma levels of tumor necrosis factor (TNF)-α and of C-reactive protein (CRP) are elevated in smokers. Previous studies failed to show an association between the G-308A polymorphism in the promoter region of ...

    Authors: Marie-Louise Gander, Joachim E Fischer, Friedrich E Maly and Roland von Känel
    Citation: BMC Cardiovascular Disorders 2004 4:17

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