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  1. ST resolution (STR) after AMI is a non-invasive indicator of IRA reperfusion. We investigated whether pre-angiography STR predicted spontaneous IRA reperfusion in STEMI patients.

    Authors: Zongsheng Guo and Xinchun Yang

    Citation: BMC Cardiovascular Disorders 2019 19:264

    Content type: Research article

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  2. High risk of embolic events exists in both patients with chronic atrial fibrillation (AF) and patients in the perioperative period of ablation (effective treatment for AF). Therefore, anticoagulant therapy is ...

    Authors: Jian Yang, Xuan Zhang, Xi-ying Wang, Chi Zhang, Song-zan Chen and Shen-Jiang Hu

    Citation: BMC Cardiovascular Disorders 2019 19:261

    Content type: Research article

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  3. Depression often co-exists with non-cardiovascular morbid conditions. Whether this comorbidity increases the risk of cardiovascular disease has so far not been studied. Thus, the aim of this study was to deter...

    Authors: Aysha Almas, Jette Moller, Romaina Iqbal, Andreas Lundin and Yvonne Forsell

    Citation: BMC Cardiovascular Disorders 2019 19:260

    Content type: Research article

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  4. Cardiovascular disease (CVD) imposes much mortality and morbidity worldwide. The use of “deep learning”, advancements in genomics, metabolomics, proteomics and devices like wearables have the potential to unea...

    Authors: Jonathan Yap, Weng Khong Lim, Anders Sahlén, Calvin Woon-Loong Chin, Kenneth Michael Yun-Chi Chew, Sonia Davila, John Allen, Vera Goh, Swee Yaw Tan, Patrick Tan, Carolyn S. P. Lam, Stuart Alexander Cook and Khung Keong Yeo

    Citation: BMC Cardiovascular Disorders 2019 19:259

    Content type: Study protocol

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  5. The new ACC/AHA hypertension guideline lower the definition of hypertension from 140/90 mmHg to 130/80 mmHg and eliminate the category of prehypertension thus increasing the prevalence of hypertension. A purpo...

    Authors: Yanxia Xie, Mingfeng Ma, Zhao Li, Xiaofan Guo, Guozhe Sun, Zhaoqing Sun, Jia Zheng, Yingxian Sun and Liqiang Zheng

    Citation: BMC Cardiovascular Disorders 2019 19:258

    Content type: Research article

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  6. Increasing evidence has been presented which suggests that left ventricular (LV) diastolic dysfunction may play an important role in the development of atrial fibrillation (AF). However, the potential for LV d...

    Authors: Fengjiao Chen, Qinliang Sun, Hairu Li, Shaohui Qu, Weidong Yu, Shuangquan Jiang and Jiawei Tian

    Citation: BMC Cardiovascular Disorders 2019 19:257

    Content type: Research article

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  7. Depression is associated with increased mortality and poor prognosis in patients with cardiovascular disease (CVD). However, little is known about the patient characteristics associated with new onset post hea...

    Authors: Serdar Sever, Patrick Doherty, Alexander Stephen Harrison and Su Golder

    Citation: BMC Cardiovascular Disorders 2019 19:256

    Content type: Research article

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  8. The risk of sudden cardiac death (SCD) is known to be dynamic. However, the accuracy of a dynamic SCD prediction is unknown. We aimed to measure the dynamic predictive accuracy of ECG biomarkers of SCD and com...

    Authors: Erick A. Perez-Alday, Aron Bender, David German, Srini V. Mukundan, Christopher Hamilton, Jason A. Thomas, Yin Li-Pershing and Larisa G. Tereshchenko

    Citation: BMC Cardiovascular Disorders 2019 19:255

    Content type: Research article

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  9. The PhysioHeart™ is a mature acute platform, based isolated slaughterhouse hearts and able to validate cardiac devices and techniques in working mode. Despite perfusion, myocardial edema and time-dependent fun...

    Authors: Benjamin Kappler, Carlos A. Ledezma, Sjoerd van Tuijl, Veronique Meijborg, Bastiaan J. Boukens, Bülent Ergin, P. J. Tan, Marco Stijnen, Can Ince, Vanessa Díaz-Zuccarini and Bas A. J. M. de Mol

    Citation: BMC Cardiovascular Disorders 2019 19:254

    Content type: Research article

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  10. Individuals with established cardiovascular disease (CVD) and risk factors such as age, smoking, hypertension, and diabetes mellitus are at an increased risk of recurrent cardiovascular events and death. The i...

    Authors: Romona D. Govender, Saif Al-Shamsi, Elpidoforos S. Soteriades and Dybesh Regmi

    Citation: BMC Cardiovascular Disorders 2019 19:253

    Content type: Research article

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  11. To assess the value of D-dimer and its combination with The Global Registry of Acute Coronary Events (GRACE) score in predicting in-hospital mortality in patients with acute coronary syndrome (ACS) undergoing ...

    Authors: Tongtong Yu, Yundi Jiao, Jia Song, Dongxu He, Jiake Wu, Zhijun Sun and Zhaoqing Sun

    Citation: BMC Cardiovascular Disorders 2019 19:252

    Content type: Research article

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  12. Heart failure (HF) is a major public health problem with increasing prevalence worldwide. It is associated with high mortality and poor quality of life due to recurrent and costly hospital admissions. Several ...

    Authors: Luciana Gioli-Pereira, Fabiana G. Marcondes-Braga, Sabrina Bernardez-Pereira, Fernando Bacal, Fábio Fernandes, Alfredo J. Mansur, Alexandre C. Pereira and José E. Krieger

    Citation: BMC Cardiovascular Disorders 2019 19:251

    Content type: Research article

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  13. Pulmonary embolism (PE) is associated to high mortality rate worldwide. However, the diagnosis of PE often results inaccurate. Many cases of PE are incorrectly diagnosed or missed and they are often associated...

    Authors: Gelsomina Mansueto, Dario Costa, Emanuele Capasso, Federica Varavallo, Giuseppina Brunitto, Rosanna Caserta, Salvatore Esposito, Massimo Niola, Celestino Sardu, Raffaele Marfella, Claudio Napoli and Mariano Paternoster

    Citation: BMC Cardiovascular Disorders 2019 19:250

    Content type: Research article

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  14. Conventional pharmacologic therapies aim to reduce fluid overload in advanced heart failure (HF) represented by intravenous (IV) loop diuretics (LDs) have sometimes not so efficacious and been reported to have...

    Authors: Ying Yang, Chao Shen, Jiangting Lu, Fen Xu, Jinshan Tong, Jiangfen Jiang and Guosheng Fu

    Citation: BMC Cardiovascular Disorders 2019 19:249

    Content type: Study protocol

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  15. There is a controversy about the association between vitamin D and cardiovascular diseases (CVDs). The effect of serum 25-OH-vitD on the risk of CVDs was evaluated.

    Authors: Fatemeh Gholami, Ghobad Moradi, Bushra Zareei, Mohammad Aziz Rasouli, Bahram Nikkhoo, Daem Roshani and Ebrahim Ghaderi

    Citation: BMC Cardiovascular Disorders 2019 19:248

    Content type: Research article

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  17. Normal findings of cardiac scintigraphy predict good outcomes. However, a paucity of the data exists for elderly patients 85 years or older. In the present study, we aimed to demonstrate the association betwee...

    Authors: Takao Kato, Mitsumasa Okano, Yoshizumi Haruna and Moriaki Inoko

    Citation: BMC Cardiovascular Disorders 2019 19:246

    Content type: Research article

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  18. The leading cause of mortality of thalassemia major patients is iron overload cardiomyopathy. Early diagnosis with searching for left ventricular diastolic dysfunction before the systolic dysfunction ensued mi...

    Authors: Benjaporn Chinprateep, Nithima Ratanasit, Yodying Kaolawanich, Khemajira Karaketklang, Pairash Saiviroonporn, Vip Viprakasit and Rungroj Krittayaphong

    Citation: BMC Cardiovascular Disorders 2019 19:245

    Content type: Research article

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  19. The independent association of neck circumference (NC) on elevated blood pressure is still uncertain in adults of China. The aim of this study is to explore such association and investigate the predictive valu...

    Authors: Huijing He, Li Pan, Feng Liu, Jingang Ma, Li Wang, Zhiping Hu, Yajun Li and Guangliang Shan

    Citation: BMC Cardiovascular Disorders 2019 19:244

    Content type: Research article

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  20. Secondary prevention after an acute myocardial infarction (AMI) reduces morbidity and mortality, but suboptimal secondary prevention of cardiovascular disease is common. Therefore, the present study aimed to i...

    Authors: Maria Sakalaki, Salim Barywani, Annika Rosengren, Lena Björck and Michael Fu

    Citation: BMC Cardiovascular Disorders 2019 19:243

    Content type: Research article

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  21. Cardiac rehabilitation (CR) programs provide significant benefit for people with cardiovascular disease. Despite these benefits, such services are not universally available. We designed and evaluated a nationa...

    Authors: Bonnie J. Wakefield, Kariann Drwal, Monica Paez, Sara Grover, Carrie Franciscus, Heather Schacht Reisinger, Peter J. Kaboli and Ramzi El Accaoui

    Citation: BMC Cardiovascular Disorders 2019 19:242

    Content type: Research article

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  22. Hypertension (HTN) is major public health challenge. Data on HTN prevalence and associated risk factors is necessary to better control it. This study aimed at estimating the prevalence of HTN and associated an...

    Authors: Biniem Hassen and Hassen Mamo

    Citation: BMC Cardiovascular Disorders 2019 19:241

    Content type: Research article

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  23. We characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9.

    Authors: Amand F. Schmidt, Michael V. Holmes, David Preiss, Daniel I. Swerdlow, Spiros Denaxas, Ghazaleh Fatemifar, Rupert Faraway, Chris Finan, Dennis Valentine, Zammy Fairhurst-Hunter, Fernando Pires Hartwig, Bernardo Lessa Horta, Elina Hypponen, Christine Power, Max Moldovan, Erik van Iperen…

    Citation: BMC Cardiovascular Disorders 2019 19:240

    Content type: Research article

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  24. Identifying variables predictive of acute myocardial infarction (AMI) in women is important. The use of the ratio of total cholesterol-to-high density lipoprotein cholesterol (TC/HDL-C) is often overlooked. Th...

    Authors: Susanna Calling, Sven-Erik Johansson, Moa Wolff, Jan Sundquist and Kristina Sundquist

    Citation: BMC Cardiovascular Disorders 2019 19:239

    Content type: Research article

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  25. Measures of abdominal adiposity are strongly associated with all-cause mortality and cardiovascular disease (CVD). However, data are limited and conflicting regarding the consequences of changes in body fat di...

    Authors: Angela A. Mulligan, Marleen A. H. Lentjes, Robert N. Luben, Nicholas J. Wareham and Kay-Tee Khaw

    Citation: BMC Cardiovascular Disorders 2019 19:238

    Content type: Research article

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  26. Cardiac catheterization is performed for both therapeutic and diagnostic reasons, in which the outcome may vary from only medical treatment to the need of percutaneous coronary intervention and ending with cor...

    Authors: Abdulsalam Alkaiyat, Reham Abumadi, Shuruq Atari, Wasef Sayeh, Hamzeh Al Zabadi, Zaid Sarawan, Fekri Bisharat and Nizar Shakhshir

    Citation: BMC Cardiovascular Disorders 2019 19:237

    Content type: Research article

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  28. Care coordination between general practitioners (GPs) and cardiovascular specialists is expected to play a key role in establishing appropriate oral anticoagulant (OAC) treatment in atrial fibrillation (AF) pa...

    Authors: Fumiko Ono, Sayako Akiyama, Akifumi Suzuki, Yoshinobu Ikeda, Akira Takahashi, Hitoshi Matsuoka, Masahiro Sasaki, Tomonori Okamura and Nariaki Yoshihara

    Citation: BMC Cardiovascular Disorders 2019 19:235

    Content type: Research article

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  29. The risk of peripheral artery disease (PAD) in patients with diabetes mellitus (DM) and coronary artery disease (CAD) is an important and inadequately addressed issue. Our aim is to examine the impact of DM on...

    Authors: Sadaf Kamil, Thomas S. G. Sehested, Nicholas Carlson, Kim Houlind, Jens F. Lassen, Casper N. Bang, Helena Dominguez, Christian T. Pedersen and Gunnar H. Gislason

    Citation: BMC Cardiovascular Disorders 2019 19:234

    Content type: Research article

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  30. Ventricular arrhythmias (VAs) arising from the origin above pulmonary valve lack comprehensive investigation. This study aimed to disclose the characteristics and radiofrequency catheter ablation (RFCA) outcom...

    Authors: Jin Li, Cheng Zheng, Zhi-Rui Liu, Jun Ma, Ge Jin, Wei-Qian Lin, Yao-Yao Wang and Jia-Feng Lin

    Citation: BMC Cardiovascular Disorders 2019 19:233

    Content type: Research article

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  31. Acute myocarditis (AM) can be defined as an inflammatory disease of the myocardium and characterized by large heterogeneity of clinical presentation. Myocarditis is becoming increasingly recognized as a contri...

    Authors: Fatih Mehmet Ucar, Cihan Ozturk and Mustafa Adem Yılmaztepe

    Citation: BMC Cardiovascular Disorders 2019 19:232

    Content type: Research article

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  32. Hypertension management in rural, resource-poor settings is difficult. Detailed understanding of patient, clinician and logistic factors which pose barriers to effective blood pressure control could enable str...

    Authors: J. P. Sibomana, R. L. McNamara and T. D. Walker

    Citation: BMC Cardiovascular Disorders 2019 19:231

    Content type: Research article

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  33. Because of previous ventricular arrhythmia (VA) episodes, patients with implantable cardioverter-defibrillator (ICD) for secondary prevention (SP) are generally considered to have a higher burden of VAs than p...

    Authors: You Zhou, Shuang Zhao, Keping Chen, Wei Hua, Yangang Su, Silin Chen, Zhaoguang Liang, Wei Xu and Shu Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:230

    Content type: Research article

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  34. Acute Coronary Syndrome (ACS) is one of the leading causes of death worldwide and studies have shown higher mortality rates and premature death in South Asian countries. The occurrence and effect of risk facto...

    Authors: Udaya Ralapanawa, Pallegoda Vithanage Ranjith Kumarasiri, Kushalee Poornima Jayawickreme, Prabashini Kumarihamy, Yapa Wijeratne, Madhushanka Ekanayake and Chandira Dissanayake

    Citation: BMC Cardiovascular Disorders 2019 19:229

    Content type: Research article

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  35. Large animal models are important in atrial fibrillation (AF) research, as they can be used to study the pathophysiology of AF and new therapeutic approaches. Unlike other animal models, horses spontaneously d...

    Authors: Eva Zander Hesselkilde, Helena Carstensen, Mette Flethøj, Merle Fenner, Ditte Dybvald Kruse, Stefan M. Sattler, Jacob Tfelt-Hansen, Steen Pehrson, Thomas Hartig Braunstein, Jonas Carlson, Pyotr G. Platonov, Thomas Jespersen and Rikke Buhl

    Citation: BMC Cardiovascular Disorders 2019 19:228

    Content type: Research article

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  36. After publication of the original article [1], we were notified that an author’s name is not complete.

    Authors: Leon L. Lutschinger, Angelos G. Rigopoulos, Peter Schlattmann, Marios Matiakis, Daniel Sedding, Paul Christian Schulze and Michel Noutsias

    Citation: BMC Cardiovascular Disorders 2019 19:227

    Content type: Correction

    Published on:

    The original article was published in BMC Cardiovascular Disorders 2019 19:207

  37. The new generation thinner-strut silicon carbide (SiC) coated cobalt chromium (CoCr) bare-metal stents (BMS) are designed to accelerate rapid endothelialisation and reduce thrombogenicity when implanted in cor...

    Authors: Kim Wadt Hansen, Raban Jeger, Rikke Sørensen, Christoph Kaiser, Matthias Pfisterer, Tor Biering-Sørensen, Louise Hougesen Bjerking and Søren Galatius

    Citation: BMC Cardiovascular Disorders 2019 19:226

    Content type: Research article

    Published on:

  38. In odontology, panoramic radiographs (PRs) are regularly performed. PRs depict the teeth and jaws as well as carotid artery calcifications (CACs). Patients with CACs on PRs have an increased risk of vascular e...

    Authors: Maria Garoff, Jan Ahlqvist, Linda-Tereza Edin, Sofia Jensen, Eva Levring Jäghagen, Fredrik Petäjäniemi, Per Wester and Elias Johansson

    Citation: BMC Cardiovascular Disorders 2019 19:225

    Content type: Research article

    Published on:

  39. Cardiovascular disease (CVD) is one of the most significant health challenges facing women today. Abuse is a serious gendered issue also affecting the health of women. Despite beginning evidence that abuse may...

    Authors: Kelly A. Scott-Storey, Marilyn Hodgins and Judith Wuest

    Citation: BMC Cardiovascular Disorders 2019 19:224

    Content type: Research article

    Published on:

  40. Coronary heart disease (CHD) is a complex disease caused by multi-factors and a major threat to human health. Circular RNAs (circRNAs) have critical roles in various biological processes and diseases. This stu...

    Authors: Yi Sun, Rong Chen, Shaowei Lin, Xiaoxu Xie, Hailing Ye, Fuli Zheng, Jie Lin, Qing Huang, Shuna Huang, Qishuang Ruan, Tingxing Zhang, Huangyuan Li and Siying Wu

    Citation: BMC Cardiovascular Disorders 2019 19:223

    Content type: Research article

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  41. Transcatheter closure of perimembranous ventricular septal defects is one of the greatest challenges in interventional cardiology. Short- and midium-term follow-up data for large samples are limited. This repo...

    Authors: Hao Li, Youyang Shi, Songyue Zhang, Yue Ren, Xing Rong, Zhenquan Wang, Tianhe Xia, Tingting Wu, Haitang Xu, Yaoyao Yan, Yi Zhan, Maoping Chu and Rongzhou Wu

    Citation: BMC Cardiovascular Disorders 2019 19:222

    Content type: Research article

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  42. Neutrophil extracellular traps (NETs) have recently been identified as mediators in atherothrombosis. Although NETosis in general has been suggested to be glucose dependent, the transferability to patients wit...

    Authors: Ragnhild Helseth, Eva Cecilie Knudsen, Jan Eritsland, Trine Baur Opstad, Harald Arnesen, Geir Øystein Andersen and Ingebjørg Seljeflot

    Citation: BMC Cardiovascular Disorders 2019 19:221

    Content type: Research article

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  43. Patients with reduced ejection fraction have high rates of mortality and readmission after hospitalization for heart failure. In Taiwan, heart failure disease management programs (HFDMPs) have proven effective...

    Authors: Shyh-Ming Chen, Yen-Nan Fang, Lin-Yi Wang, Ming-Kung Wu, Po-Jui Wu, Tsung-Hsun Yang, Yung-Lung Chen and Chi-Ling Hang

    Citation: BMC Cardiovascular Disorders 2019 19:220

    Content type: Research article

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  44. Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function. Cardiac fibroblasts surely influence this process. Besides, macrophage plays an essential role in cardiac r...

    Authors: Yan Che, Di-Fei Shen, Zhao-Peng Wang, Ya-Ge Jin, Qing-Qing Wu, Sha-Sha Wang and Yuan Yuan

    Citation: BMC Cardiovascular Disorders 2019 19:219

    Content type: Research article

    Published on:

  45. Cardiovascular disease (CVD) is the leading cause of death worldwide. Some studies have suggested anassociation between serum uric acid levels and cardiovascular mortality; however, the results have not been s...

    Authors: Fatemeh Rahimi-Sakak, Mahsa Maroofi, Jamal Rahmani, Nick Bellissimo and Azita Hekmatdoost

    Citation: BMC Cardiovascular Disorders 2019 19:218

    Content type: Research article

    Published on:

  46. Cardiac power output (CPO), derived from the product of cardiac output and mean aortic pressure, is an important yet underexploited parameter for hemodynamic monitoring of critically ill patients in the intens...

    Authors: Dawud Abawi, Alessandro Faragli, Michael Schwarzl, Martin Manninger, David Zweiker, Karl-Patrik Kresoja, Jochen Verderber, Birgit Zirngast, Heinrich Maechler, Paul Steendijk, Burkert Pieske, Heiner Post and Alessio Alogna

    Citation: BMC Cardiovascular Disorders 2019 19:217

    Content type: Research article

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  47. Infantile hepatic hemangioma (IHH) is a rare endothelial cell neoplasm, which may be concurrent with severe complications and result in poor outcomes. Moreover, the coexistence of IHH and congenial heart disea...

    Authors: Xin-tong Zhang, Wei-dong Ren, Guang Song, Yang-jie Xiao, Fei-fei Sun and Nan Wang

    Citation: BMC Cardiovascular Disorders 2019 19:216

    Content type: Case report

    Published on:

  48. There is limited information regarding left atrial (LA) mechanics in aortic valve stenosis (AS). We assessed LA mechanics in AS through speckle-tracking echocardiography (STE) according to severity and prognosis.

    Authors: Patrícia Marques-Alves, Ana Vera Marinho, Rogério Teixeira, Rui Baptista, Graça Castro, Rui Martins and Lino Gonçalves

    Citation: BMC Cardiovascular Disorders 2019 19:215

    Content type: Research article

    Published on:

  49. First-degree atrioventricular block (AVB) has traditionally been regarded as a benign condition but recent studies have challenged this conception. Prevalence of 1–2% have been reported in developed countries ...

    Authors: Zhi Du, Liying Xing, Min Lin, Yuanmeng Tian, Li Jing, Han Yan, Boqiang Zhang, Shuang Liu, Shiwen Yu and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2019 19:214

    Content type: Research article

    Published on:

  50. The role of apolipoprotein E gene (APOE) in lipid metabolism has been well established, and APOE is associated with the risk of cardiovascular disease (CVD) and diabetes mellitus (DM). However, the relationshi...

    Authors: Sudong Liu, Jing Liu, Ruiqiang Weng, Xiaodong Gu and Zhixiong Zhong

    Citation: BMC Cardiovascular Disorders 2019 19:213

    Content type: Research article

    Published on:

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