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  1. Left atrial (LA) volume (LAV) is one of the recommended key variables for evaluating left ventricular (LV) diastolic function. However, only LA anteroposterior diameter (LAAP) is available in numerous large-sc...

    Authors: Yonghuai Wang, Liang Zhang, Shuang Liu, Guangyuan Li, Fanxin Kong, Cuiting Zhao, Jun Yang and Chunyan Ma

    Citation: BMC Cardiovascular Disorders 2021 21:110

    Content type: Research article

    Published on:

  2. Observational studies suggest that early menopause is associated with increased risk of death and cardiovascular disease (CVD); however, the results of these studies have been inconsistently. We aimed to asses...

    Authors: Yan Li, Dong Zhao, Miao Wang, Jia-yi Sun, Jun Liu, Yue Qi, Yong-chen Hao, Qiu-ju Deng, Jue Liu, Jing Liu and Min Liu

    Citation: BMC Cardiovascular Disorders 2021 21:109

    Content type: Research article

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  3. The natural history of patients with moderate aortic stenosis (AS) is poorly understood. We aimed to determine the long-term outcomes of patients with moderate AS.

    Authors: Yu Du, Mario Gössl, Santiago Garcia, Maurice Enriquez-Sarano, Joao L. Cavalcante, Richard Bae, Go Hashimoto, Miho Fukui, Bernardo Lopes, Aisha Ahmed, Christian Schmidt, Larissa Stanberry, Ross Garberich, Steven M. Bradley, Robert Steffen and Paul Sorajja

    Citation: BMC Cardiovascular Disorders 2021 21:108

    Content type: Research article

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  4. Cardiac magnetic resonance feature tracking (CMR-FT) and speckle tracking echocardiography (STE) are well-established strain imaging modalities. Multilayer strain measurement permits independent assessment of ...

    Authors: Saikrishna Ananthapadmanabhan, Giau Vo, Tuan Nguyen, Hany Dimitri and James Otton

    Citation: BMC Cardiovascular Disorders 2021 21:107

    Content type: Research article

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  5. Conventional risk factors for sudden cardiac death (SCD) justify primary prevention through implantable cardioverter-defibrillator (ICD) implantation in hypertrophic cardiomyopathy (HCM) patients. However, the...

    Authors: Kyoichiro Yazaki, Atsushi Suzuki, Tsuyoshi Shiga, Yuichiro Minami, Kotaro Arai, Kyomi Ashihara, Morio Shoda and Nobuhisa Hagiwara

    Citation: BMC Cardiovascular Disorders 2021 21:106

    Content type: Research article

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  7. Studies have demonstrated that heart failure (HF) patients who receive direct pharmacist input as part of multidisciplinary care have better clinical outcomes. This study evaluated/compared the difference in p...

    Authors: Daya Ram Parajuli, Sepehr Shakib, Joanne Eng-Frost, Ross A. McKinnon, Gillian E. Caughey and Dean Whitehead

    Citation: BMC Cardiovascular Disorders 2021 21:104

    Content type: Research article

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  8. Atrial fibrillation (AF) is the most common cardiac arrhythmia. Type 2 diabetes (T2D) is an independent risk factor for AF. The cardioembolic stroke (CS) risk is increased when both conditions coexist. Whether...

    Authors: Cheng Liu, Jingxian Pei, Yanxian Lai, Tianwang Guan, Abudurexiti Zeyaweiding, Tutiguli Maimaiti, Haiyan Zhao and Yan Shen

    Citation: BMC Cardiovascular Disorders 2021 21:103

    Content type: Research article

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  9. Evidence linking homocysteine (Hcy) with cardiovascular diseases (CVD) or its risk factors are limited in a sub-Saharan black population.

    Authors: Babangida S. Chori, Benjamin Danladi, Bassey A. Inyang, Michael P. Okoh, Maxwell M. Nwegbu, Adewale L. Alli and Augustine N. Odili

    Citation: BMC Cardiovascular Disorders 2021 21:102

    Content type: Research article

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  10. Aerobic exercise improves endothelial function and arterial stiffness after myocardial infarction (MI), but the effects of isometric exercise on cardiovascular parameters are still uncertain. We aimed to asses...

    Authors: Daniel P. Kollet, Ana Beatriz Marenco, Nathan L. Bellé, Eduardo Barbosa, Liliana Boll, Bruna Eibel, Gustavo Waclawovsky and Alexandre Machado Lehnen

    Citation: BMC Cardiovascular Disorders 2021 21:101

    Content type: Research article

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  11. Chronic kidney disease (CKD) are associated with acute myocardial infarction (AMI). High-sensitive cardiac troponin (hs-cTn) has been evidenced to enhance the early diagnostic accuracy of AMI, but hs-cTn level...

    Authors: Daijin Ren, Tianlun Huang, Xin Liu and Gaosi Xu

    Citation: BMC Cardiovascular Disorders 2021 21:100

    Content type: Research article

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  12. We investigated the association between levels of leisure-time physical activity and vascular stiffness in a longitudinal observational study from a representative Swedish population.

    Authors: Gábor Szaló, Margareta Hellgren, Matthew Allison, Lennart Råstam, Ulf Lindblad and Bledar Daka

    Citation: BMC Cardiovascular Disorders 2021 21:99

    Content type: Research article

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  13. Inflammation is involved in the progression of degenerative valvular heart disease (DVHD). microRNA-222 (miR-222) contributes to inflammation-mediated vascular remodeling, but its involvement in DVHD in relati...

    Authors: Hualan Zhou, Sen Lin, Xia Li, Dianxuan Guo, Yun Wang and Youdong Hu

    Citation: BMC Cardiovascular Disorders 2021 21:98

    Content type: Research article

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  14. To investigate the ability of body shape index (ABSI), body roundness index (BRI), waist circumference (WC), body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), and body adiposity in...

    Authors: Jinjian Xu, Liqun Zhang, Qiong Wu, Yaohan Zhou, Ziqi Jin, Zhijian Li and Yimin Zhu

    Citation: BMC Cardiovascular Disorders 2021 21:97

    Content type: Research article

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  15. Sevoflurane postconditioning (SevP) effectively relieves myocardial ischemia/reperfusion (I/R) injury but performs poorly in the diabetic myocardium. Previous studies have revealed the important role of increa...

    Authors: Jing Yu, Jiandong He, Wenqu Yang, Xiang Wang, Gaoxiang Shi, Yinglei Duan, Hui Wang and Chongfang Han

    Citation: BMC Cardiovascular Disorders 2021 21:96

    Content type: Research article

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  16. Thoracic aortic endovascular repair (TEVAR) of uncomplicated type B aortic dissection (uTBAD) has favorable long-term outcomes but higher early adverse events compared with the optimal medical treatment. Recen...

    Authors: Hongqiao Zhu, Lei Zhang, Taiping Liang, Yiming Li, Jian Zhou and Zaiping Jing

    Citation: BMC Cardiovascular Disorders 2021 21:95

    Content type: Research article

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  17. The CHA2DS2-VASc scoring system is correlated with left atrial (LA) reservoir function in patients with atrial fibrillation (AF) rhythm or paroxysmal AF. We assessed the ability of CHA2DS2-VASc to grade LA functi...

    Authors: Marjan Hadadi, Reza Mohseni-Badalabadi and Ali Hosseinsabet

    Citation: BMC Cardiovascular Disorders 2021 21:94

    Content type: Research article

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  18. Both exercise and cold exposure increase blood coagulation potential but their combined effects are not known. The purpose of the present study was to assess blood coagulation factors in response to submaximal...

    Authors: Karri Parkkila, Rasmus I. P. Valtonen, Leena Hiltunen, Heidi E. Hintsala, Jouni J. K. Jaakkola and Tiina M. Ikäheimo

    Citation: BMC Cardiovascular Disorders 2021 21:93

    Content type: Research article

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  19. The impact of reduction in glycemic excursion on coronary plaques remains unknown. This study aimed to elucidate whether a dipeptidyl peptidase 4 inhibitor could reduce the glycemic excursion and stabilize the...

    Authors: Hiroyuki Yamamoto, Akihide Konishi, Toshiro Shinke, Hiromasa Otake, Masaru Kuroda, Tsuyoshi Osue, Takahiro Sawada, Tomofumi Takaya, Hiroya Kawai, Naoko Hashimoto, Takeshi Ohara, Yushi Hirota, Kazuhiko Sakaguchi, Takashi Omori, Wataru Ogawa and Ken-ichi Hirata

    Citation: BMC Cardiovascular Disorders 2021 21:92

    Content type: Research article

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  20. An amendment to this paper has been published and can be accessed via the original article.

    Authors: M. Unverdorben, C. von Heymann, A. Santamaria, M. Saxena, T. Vanassche, J. Jin, P. Laeis, R. Wilkins, C. Chen and P. Colonna

    Citation: BMC Cardiovascular Disorders 2021 21:91

    Content type: Correction

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    The original article was published in BMC Cardiovascular Disorders 2020 20:504

  21. Recent studies have reported the effects of metabolic syndrome (MetS) and its components on atrial fibrillation (AF), but the results remain controversial. Therefore, we performed a meta-analysis to evaluate t...

    Authors: Ying Zheng, Zengshuo Xie, Jiayong Li, Chen Chen, Wenting Cai, Yugang Dong, Ruicong Xue and Chen Liu

    Citation: BMC Cardiovascular Disorders 2021 21:90

    Content type: Research article

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  22. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Marek J. Jasinski, Karol Miszalski-Jamka, Kinga Kosiorowska, Radoslaw Gocol, Izabella Wenzel-Jasinska, Grzegorz Bielicki, Mikolaj Berezowski, Marceli Lukaszewski, Andrzej Kansy and Marek A. Deja

    Citation: BMC Cardiovascular Disorders 2021 21:89

    Content type: Correction

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    The original article was published in BMC Cardiovascular Disorders 2021 21:13

  23. Necrotizing autoimmune myopathy (NAM) is pathologically characterized by myofiber necrosis and regeneration with paucity or absence of inflammatory cells in muscle biopsy. Two autoantibodies, namely anti-signa...

    Authors: Xue Ma, Li Xu, Yue Li and Bitao Bu

    Citation: BMC Cardiovascular Disorders 2021 21:88

    Content type: Case report

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  24. Hypertension and/or myocardial infarction are common causes of heart failure in Type 2 diabetes. Progression to heart failure is usually preceded by ventricular dysfunction, linked to matrix metalloproteinase ...

    Authors: Chris Watson, J. Paul Spiers, Max Waterstone, Adam Russell-Hallinan, Joseph Gallagher, Kenneth McDonald, Cristin Ryan, John Gilmer and Mark Ledwidge

    Citation: BMC Cardiovascular Disorders 2021 21:87

    Content type: Research article

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  26. There is a paucity of data regarding acute phase (in-hospital and 30-day) major adverse cardiac events (MACE) following ST-segment elevation myocardial infarction (STEMI) in Bangladesh. This study aimed to doc...

    Authors: Zubair Akhtar, Mohammad Abdul Aleem, Probir Kumar Ghosh, A. K. M. Monwarul Islam, Fahmida Chowdhury, C. Raina MacIntyre and Ole Fröbert

    Citation: BMC Cardiovascular Disorders 2021 21:85

    Content type: Research article

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  27. The ablation targets of atrial fibrillation (AF) are adjacent to bronchi and pulmonary arteries (PAs). We used computed tomography (CT) to evaluate the anatomical correlation between left atrium (LA)-pulmonary...

    Authors: Yan-Jing Wang, Huan Sun, Xiao-Fei Fan, Meng-Chao Zhang, Ping Yang, Hong Zeng and Lin Liu

    Citation: BMC Cardiovascular Disorders 2021 21:84

    Content type: Research article

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  28. Resting 12-lead electrocardiography is widely used for the detection of cardiac diseases. Electrocardiogram readings have been reported to be affected by aging and, therefore, can predict patient mortality.

    Authors: Naomi Hirota, Shinya Suzuki, Takuto Arita, Naoharu Yagi, Takayuki Otsuka, Mikio Kishi, Hiroaki Semba, Hiroto Kano, Shunsuke Matsuno, Yuko Kato, Tokuhisa Uejima, Yuji Oikawa, Minoru Matsuhama, Mitsuru Iida, Tatsuya Inoue, Junji Yajima…

    Citation: BMC Cardiovascular Disorders 2021 21:83

    Content type: Research article

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  29. Liver enzymes, including alanine aminotransferase (ALT) and aspartate aminotransferase (AST), are markers of hepatic dysfunction and fatty liver disease. Although ALT and AST have been suggested as risk factor...

    Authors: Jian Li, Zhuo Zhao, Hui Jiang, Minjie Jiang, Ge Yu and Xu Li

    Citation: BMC Cardiovascular Disorders 2021 21:82

    Content type: Research article

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  30. Myocardial iron overload in patients with thalassemia major (TM) is one of the most important complications. The purpose of the study was to identify advanced echocardiography parameters for early identificati...

    Authors: Michael J. Bonios, Epameinontas Fountas, Polyxeni Delaporta, Stamatis Kyrzopoulos, Antonis Kattamis, Stamatis N. Adamopoulos and Dimitris Tsiapras

    Citation: BMC Cardiovascular Disorders 2021 21:81

    Content type: Research article

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  31. In Russia, cardiovascular disease (CVD) mortality is high and the mortality gap between men and women is large. Conventional risk factors cannot explain these phenomena. Ventricular arrhythmia (VA) is an impor...

    Authors: Maria A. Shkolnikova, Rukijat A. Ildarova, Dmitri A. Jdanov, Svetlana A. Shalnova and Vladimir M. Shkolnikov

    Citation: BMC Cardiovascular Disorders 2021 21:80

    Content type: Research article

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  32. Coronary artery disease (CAD) remains one of the leading causes of mortality and morbidity worldwide. As oxygen and nutrient supply to the myocardium significantly decrease during ischemic periods, important c...

    Authors: Efstratios Karagiannidis, Georgios Sofidis, Andreas S. Papazoglou, Olga Deda, Eleftherios Panteris, Dimitrios V. Moysidis, Nikolaos Stalikas, Anastasios Kartas, Anastasios Papadopoulos, Leandros Stefanopoulos, Haralambos Karvounis, Helen Gika, Georgios Theodoridis and Georgios Sianos

    Citation: BMC Cardiovascular Disorders 2021 21:79

    Content type: Study protocol

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  33. ATP-binding cassette transporter A1 (ABCA1) plays a major role in high-density lipoprotein (HDL) metabolism and reverse cholesterol transport (RCT) and exerts anti-inflammatory effects. Increased ABCA1 promoter m...

    Authors: Fang An, Chao Liu, Xiujuan Wang, Tan Li, Hao Fu, Buhe Bao, Hongliang Cong and Jihong Zhao

    Citation: BMC Cardiovascular Disorders 2021 21:78

    Content type: Research article

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  34. Patients who receive percutaneous coronary intervention (PCI) have different chances of developing in-stent restenosis (ISR). To date, no predictable biomarker can be applied in the clinic. MicroRNAs (miRNAs o...

    Authors: Chun-Hsu Pan, Shu-Chen Chien, Chang-Jui Chen, Chun-Ming Shih, Ming-Hsiung Hsieh, Chun-Yao Huang, Wei-Fung Bi, Chao-Shun Chan, Yung-Ta Kao, Cheng-Yi Hsiao, Shuo-Ju Chiang, Kuang-Hsing Chiang, Jen-Hung Huang, Yun-Ru Liu, Ji-Dung Luo, Hui-Yu Huang…

    Citation: BMC Cardiovascular Disorders 2021 21:77

    Content type: Research article

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  35. This study aimed to determine the left ventricular (LV) systolic function in patients on maintenance hemodialysis (MHD) using the myocardial work (MW) technique and investigate the clinical value of the MW tec...

    Authors: Chang Liu, Yi-Ping Feng, Zi-Ning Yan, Li Fan, Yi-Fei Rui and Ling Cui

    Citation: BMC Cardiovascular Disorders 2021 21:76

    Content type: Research article

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  36. Proton pump inhibitors (PPIs) are frequently prescribed to patients with coronary heart disease (CHD) under antiplatelet therapy to prevent gastrointestinal (GI) bleeding. However, its clinical impact is still...

    Authors: Wanbing He, Xiaorong Shu, Enyi Zhu, Bingqing Deng, Yongqing Lin, Xiaoying Wu, Zenan Zhou, Jingfeng Wang and Ruqiong Nie

    Citation: BMC Cardiovascular Disorders 2021 21:75

    Content type: Research article

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  37. Serum microRNAs (miRNAs) have been used as novel biomarkers for various diseases, including acute coronary syndrome (ACS). This study aimed to investigate the expression and clinical significance of microRNA-3...

    Authors: Wenqing Zhang, Guannan Chang, Liya Cao and Gang Ding

    Citation: BMC Cardiovascular Disorders 2021 21:74

    Content type: Research article

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  38. There is an individual variation in response to antihypertensive effect of the angiotensin II receptor antagonist. This study aimed to determine the allele and genotype frequencies of CYP2C9 and AGTR1 genetic pol...

    Authors: Keping Chen, Peng Xiao, Guochun Li, Chunling Wang and Chuankun Yang

    Citation: BMC Cardiovascular Disorders 2021 21:73

    Content type: Research article

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  39. Left ventricular negative remodelling after ST-segment elevation myocardial infarction (STEMI) is considered as the major cause for the poor prognosis. But the predisposing factors and potential mechanisms of ...

    Authors: Shuai Meng, Yong Zhu, Kesen Liu, Ruofei Jia, Jing Nan, Maolin Chen, Xuan Lei, Kaiyuan Zou and Zening Jin

    Citation: BMC Cardiovascular Disorders 2021 21:72

    Content type: Research article

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  40. This study aimed to examine the relationship between oral health status and hygiene behavior among adults and elderly with preceding chronic disease or coronary artery disease history.

    Authors: Sun Kyung Lee and Seon Young Hwang

    Citation: BMC Cardiovascular Disorders 2021 21:71

    Content type: Research article

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  41. Risk stratification of patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) is an important clinical method, but long-term studies on patients subjected to all-treatment strategies are lacking. Th...

    Authors: Ivica Kristić, Nikola Crnčević, Frane Runjić, Vesna Čapkun, Ozren Polašek, Andrija Matetic and Mislav Vrsalovic

    Citation: BMC Cardiovascular Disorders 2021 21:70

    Content type: Research article

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  42. This meta-analysis based on prospective cohort studies aimed to evaluate the associations of lipid profiles with the risk of major adverse cardiovascular outcomes in patients with coronary heart disease (CHD).

    Authors: Xiangmei Zhao, Dongying Wang and Lijie Qin

    Citation: BMC Cardiovascular Disorders 2021 21:69

    Content type: Research article

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  43. Coronary artery disease (CAD) is characterized by narrowing/ blockade of coronary arteries that is mainly caused by atherosclerotic plaques. Considering the involvement of platelet abnormalities, such as defec...

    Authors: Farideh Malakootikhah, Hossein Naghavi, Negar Firouzabadi, Mohsen Maadani, Massoumeh Shafiei and Nader Tajik

    Citation: BMC Cardiovascular Disorders 2021 21:68

    Content type: Research article

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  44. Radial artery occlusion is a common complication after coronary angiography and percutaneous coronary intervention via the transradial access. In recent years, coronary angiography and percutaneous coronary in...

    Authors: Feng Li, Gan-Wei Shi, Bi-Feng Zhang, Xiao-Long Yu, Hao-Min Huang, Jian-Qiang Xiao and Gao-Jun Cai

    Citation: BMC Cardiovascular Disorders 2021 21:67

    Content type: Case report

    Published on:

  45. To evaluate the predictive value of the index of microcirculatory resistance (IMR) for long-term cardiac systolic function after primary percutaneous coronary intervention (pPCI) in patients with acute anterio...

    Authors: Yu Qi, Rong Gu, Jiamin Xu, Lina Kang, Yihai Liu, Lian Wang, Jianzhou Chen, Jingmei Zhang and Kun Wang

    Citation: BMC Cardiovascular Disorders 2021 21:66

    Content type: Research article

    Published on:

  46. Ischaemic heart disease (IHD) often develops after decades of preceding subclinical coronary atherosclerosis. Biomarkers are useful prognostic predictors of IHD, but their long-term predictive value in a gener...

    Authors: Maria Sakalaki, Per-Olof Hansson, Annika Rosengren, Erik Thunström, Aldina Pivodic and Michael Fu

    Citation: BMC Cardiovascular Disorders 2021 21:65

    Content type: Research article

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2021 21:111

  47. This study examines the association between socioeconomic and lifestyle factors and the prevalence of hypertension among elderly individuals in rural Southwest China.

    Authors: Li Xiao, Cai Le, Gui-Yi Wang, Lu-Ming Fan, Wen-Long Cui, Ying-Nan Liu, Jing-Rong Shen and Allison Rabkin Golden

    Citation: BMC Cardiovascular Disorders 2021 21:64

    Content type: Research article

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  48. Hypertriglyceridemic waist (HTGW), which incorporates measures of waist circumference and levels of triglyceride in blood, could act as an early-stage predictor to identify the individuals at high-risk for sub...

    Authors: Peyman Namdarimoghaddam, Adeleke Fowokan, Karin H. Humphries, G. B. John Mancini and Scott Lear

    Citation: BMC Cardiovascular Disorders 2021 21:63

    Content type: Research article

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  49. Previous studies have reported a high prevalence of hypertension in Iranian students, especially in rural areas. The aim of this study was to investigate the daily intake of salt in students and its associatio...

    Authors: Mohammad Hassan Emamian, Hossein Ebrahimi, Hassan Hashemi and Akbar Fotouhi

    Citation: BMC Cardiovascular Disorders 2021 21:62

    Content type: Research article

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  50. Atherosclerosis (AS) is a chronic inflammatory disorder. The aim of our study was to explore the role of circular RNA (circRNA) transmembrane 7 superfamily member 3 (circTM7SF3) in AS progression.

    Authors: Xiaojuan Wang and Ming Bai

    Citation: BMC Cardiovascular Disorders 2021 21:51

    Content type: Research article

    Published on:

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