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  1. Although the detrimental effects of advanced chronic kidney disease (CKD) on prognosis in coronary artery disease is known, there are few data on the efficacy and safety of modern interventional therapies and ...

    Authors: Johannes Schmucker, Andreas Fach, Rico Osteresch, Luis Alberto Mata Marin, Tina Retzlaff, Stephan Rühle, Daniela Garstka, Uwe Kuhlmann, Ingo Eitel, Rainer Hambrecht and Harm Wienbergen
    Citation: BMC Cardiovascular Disorders 2022 22:142
  2. Renin–angiotensin–aldosterone-system inhibitors markedly play an active role in the primary prevention of atrial fibrillation (AF), but the impact of angiotensin-converting enzyme inhibitors (ACEIs) or angiote...

    Authors: Wei Xu, Yan-min Yang, Jun Zhu, Shuang Wu, Juan Wang, Han Zhang and Xing-hui Shao
    Citation: BMC Cardiovascular Disorders 2022 22:141
  3. Ideal “cardiovascular health” (CVH)–optimal diet, exercise, nonsmoking, BMI, BP, lipids, and glucose—is associated with healthy longevity in adults. Pediatric heart transplant (HT) patients may be at risk for ...

    Authors: Carmel Bogle, Amanda Marma Perak, Sarah J. Wilkens, Alaa Aljiffry, Karen Rychlik, John M. Costello, Donald M. Lloyd-Jones and Elfriede Pahl
    Citation: BMC Cardiovascular Disorders 2022 22:139
  4. Pulmonary hypertension in left heart disease (PH-LHD), which includes combined post- and precapillary PH (Cpc-PH) and isolated postcapillary PH (Ipc-PH), differs significantly in prognosis. We aimed to assess ...

    Authors: Xiu-Jun Zhong, Rong Jiang, Lu Yang, Ping Yuan, Su-Gang Gong, Qin-Hua Zhao, Ci-Jun Luo, Hong-Ling Qiu, Hui-Ting Li, Rui Zhang, Jing He, Lan Wang, Jie Tang and Jin-Ming Liu
    Citation: BMC Cardiovascular Disorders 2022 22:137
  5. This study evaluates cardiac diseases and prognosis in young adults and adults presenting with ventricular tachyarrhythmias (VTA).

    Authors: Kathrin Weidner, Michael Behnes, Tobias Schupp, Jorge Hoppner, Ibrahim El-Battrawy, Uzair Ansari, Ahmad Saleh, Gabriel Taton, Linda Reiser, Armin Bollow, Thomas Reichelt, Dominik Ellguth, Niko Engelke, Thomas Bertsch, Dirk Große Meininghaus, Ursula Hoffmann…
    Citation: BMC Cardiovascular Disorders 2022 22:136
  6. Conduction disturbances are a common complication after transcatheter aortic valve replacement (TAVR). The aim of this study was to investigate the preprocedural and procedural variables that predict new-onset...

    Authors: Wongsaput Boonyakiatwattana, Adisak Maneesai, Vithaya Chaithiraphan, Decho Jakrapanichakul, Pranya Sakiyalak, Narathip Chunhamaneewat, Worawong Slisatkorn, Chunhakasem Chotinaiwattarakul, Rungtiwa Pongakasira and Nattawut Wongpraparut
    Citation: BMC Cardiovascular Disorders 2022 22:135
  7. Fibrosing mediastinitis (FM) complicated with pulmonary hypertension (PH) has been considered as an important cause of morbidity and mortality. This study was designed to observe the possible effects of abnorm...

    Authors: Xinyuan Zhang, Shu Zhang, Jianfeng Wang, Wei Jiang, Lanlan Sun, Yuanzhi Li, Dichen Guo, Yuanhua Yang, Xiuzhang Lu and Yidan Li
    Citation: BMC Cardiovascular Disorders 2022 22:134
  8. Isoproterenol (ISO), a synthetic on selective β-adrenergic agonist, provides a simple and non-invasive method for inducing myocardial injury with lower mortality and higher reproducibility. Phlegm-damp syndrom...

    Authors: Taohua Lan, Qiaohuang Zeng, Wei Jiang, Tong Liu, Wenjing Xu, Ping Yao and Weihui Lu
    Citation: BMC Cardiovascular Disorders 2022 22:133
  9. High levels of participation in leisure-time and household physical activity lower the risk of cardiovascular disease (CVD), although it is unclear whether the number of activity types is related to new-onset ...

    Authors: Hiroaki Iwase, Sachiko Tanaka-Mizuno, Naoyuki Takashima, Aya Kadota, Kenji Matsui, Yasuyuki Nakamaura, Katsuyuki Miura, Hirotsugu Ueshima and Yoshikuni Kita
    Citation: BMC Cardiovascular Disorders 2022 22:132
  10. Hypertension is the leading cause of morbi-mortality in our country. Thus, we conducted this national survey on hypertension to analyze the profile of the Tunisian hypertensive patient and to assess the level ...

    Authors: Leila Abid, Rania Hammami, Ikram Chamtouri, Meriam Drissa, Selim Boudiche, MohamedAmine Bahloul, Hedi BenSlima, Khaled Sayahi, Selma Charfeddine, Emna Allouche, Lamia Rais, Badr Kaab, Hassen IbnHadjamor, Lilia BenFatma, Riadh Garbaa, Sabrine Boukhris…
    Citation: BMC Cardiovascular Disorders 2022 22:131
  11. Levosimendan can improve clinical symptoms and the cardiorenal rescue success rate, and stabilize hemodynamic parameters in individuals suffering from acute decompensated heart failure. In addition, Shenfu inj...

    Authors: Miaomiao Li, Yue Zhang, Qianli Wan, Yiou Li, Tianzhen Qu and Fang Yuan
    Citation: BMC Cardiovascular Disorders 2022 22:130
  12. Genetic factors play an important role in susceptibility to hypertension. Herein, the association between acetaldehyde dehydrogenase 2 (ALDH2) and methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms...

    Authors: Heming Wu, Qingyan Huang, Zhikang Yu and Zhixiong Zhong
    Citation: BMC Cardiovascular Disorders 2022 22:128
  13. Various parameters of mechanical dyssynchrony have been proposed to improve patient selection criteria for cardiac resynchronization therapy, but sensitivity and specificity are lacking. However, echocardiogra...

    Authors: Louis S. Fixsen, Philippe C. Wouters, Richard G. P. Lopata and Hareld M. C. Kemps
    Citation: BMC Cardiovascular Disorders 2022 22:127
  14. Myocardial infarction (MI) remains the leading cause of death and disability among cardiovascular diseases worldwide. Studies show that elevated low-density lipid protein cholesterol (LDL-C) levels confer the ...

    Authors: Aiyu Shao, Jikang Shi, Zhuoshuai Liang, Lingfeng Pan, Wenfei Zhu, Sainan Liu, Jiayi Xu, Yanbo Guo, Yi Cheng and Yichun Qiao
    Citation: BMC Cardiovascular Disorders 2022 22:126
  15. Current guidelines indicate we can consider a bridging strategy that uses intravenous, reversible glycoprotein inhibitors for patients that required surgery following recent stent implantation. However, no str...

    Authors: Fan Wu, Kanghua Ma, Rui Xiang, Baoru Han, Jing Chang, Zhong Zuo, Yue Luo and Min Mao
    Citation: BMC Cardiovascular Disorders 2022 22:125
  16. Outpatients seek to visit health care facilities for episodes of tachycardia-related signs and symptoms. The challenge for physicians is to balance a proper initial assessment and avoid overlooking a possible ...

    Authors: Ann-Katrin Nordblom, Gabriella Norberg Boysen, Mia Berglund and Anna Kjellsdotter
    Citation: BMC Cardiovascular Disorders 2022 22:124
  17. The influence of renin–angiotensin–aldosterone system (RAAS) inhibitors on the critically ill COVID-19 patients with pre-existing hypertension remains uncertain. This study examined the impact of previous use ...

    Authors: Kei Sato, Nicole White, Jonathon P. Fanning, Nchafatso Obonyo, Michael H. Yamashita, Vinesh Appadurai, Anna Ciullo, Meryta May, Elliott T. Worku, Leticia Helms, Shinichiro Ohshimo, Dafsah A. Juzar, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser and Rakesh C. Arora
    Citation: BMC Cardiovascular Disorders 2022 22:123
  18. Stem-cell derived in vitro cardiac models have provided profound insights into mechanisms in cardiac development and disease. Efficient differentiation of specific cardiac cell types from human pluripotent ste...

    Authors: Dilip Thomas, Vinicio A. de Jesus Perez and Nazish Sayed
    Citation: BMC Cardiovascular Disorders 2022 22:122
  19. Bleedings are frequent and dreaded complications in heart failure patients with ventricular assist devices (VAD). Serotonin reuptake inhibitor (SRI) antidepressants are widely used to treat depression in these...

    Authors: Bianca Auschra, Markus J. Wilhelm, Claudia Husung, Josef Jenewein, Andreas J. Flammer and Lena Jellestad
    Citation: BMC Cardiovascular Disorders 2022 22:121
  20. Radial artery (RA) atherosclerosis in acute coronary syndrome (ACS) patients has not been systematically observed in vivo. The study aims to characterize plaque morphology and intimal hyperplasia of the RA in ...

    Authors: Zixuan Li, Zhe Tang, Yujie Wang, Zijing Liu, Guozhong Wang, Libin Zhang, Yongxia Wu and Jincheng Guo
    Citation: BMC Cardiovascular Disorders 2022 22:120
  21. Obesity is a well-known modified risk factor for isolated systolic hypertension (ISH), but evidence is lacking regarding whether the combination of anthropometric and lipid indicators could strengthen their co...

    Authors: Jian Dong Qian, Xiao Mei Li, Dong Shui Chen, Jian Qin Zhu and Xing Zhen Liu
    Citation: BMC Cardiovascular Disorders 2022 22:119
  22. Endothelial progenitor cells (EPCs) are circulating angiogenic cells with endothelial features associated with risk for stroke. We aimed to delve into their functional characteristics. EPCs were isolated and c...

    Authors: Francisco Rodríguez-Esparragón, Laura B. Torres-Mata, Juan Carlos López-Fernández, Laura Cappiello, Jesús M. González-Martín, Bernardino Clavo, Jaime A. Serna-Gómez, Lidia Estupiñán-Quintana, Cristina Torres-Ascensión and Jesús Villar
    Citation: BMC Cardiovascular Disorders 2022 22:118
  23. The partial upper sternotomy (PUS) approach is acceptable for aortic valve replacement, and even aortic root operation. However, the efficiency of PUS for extensive arch repair of acute type A aortic dissectio...

    Authors: Zhihuang Qiu, Jun Xiao, Qingsong Wu, Tianci Chai, Li Zhang, Yumei Li and Liangwan Chen
    Citation: BMC Cardiovascular Disorders 2022 22:117
  24. One of the global problems is to control the coronavirus epidemic, and the role of different medicines is still unknown to policymakers. This study was conducted to evaluate the effects of losartan on the mort...

    Authors: Mohammadreza Mirjalili, Moslem Taheri Soodejani, Mehdi Raadabadi, Ali Dehghani and Fateme Salemi
    Citation: BMC Cardiovascular Disorders 2022 22:116
  25. Infective endocarditis (IE) is a complex disease for which the European Society of Cardiology guideline recommends a dedicated multidisciplinary endocarditis team (ET) approach since 2015. It is currently unkn...

    Authors: F. M. A. van den Heuvel, M. Bos, G. S. C. Geuzebroek, E. H. J. G. Aarntzen, I. Maat, H. J. Dieker, M. Verkroost, L. Rodwell, J. ten Oever, R. van Crevel, J. Habets, I. J. E. Kouijzer and R. Nijveldt
    Citation: BMC Cardiovascular Disorders 2022 22:114
  26. No-reflow phenomenon (NRP) is one of the complications that mostly occur during percutaneous coronary intervention (PCI). In this study, we comprehensively examined the relationship between the model for end-s...

    Authors: Xin-Tao Zhang, Zhao-Rong Lin, Lin Zhang, Zi-Wen Zhao and Liang-Long Chen
    Citation: BMC Cardiovascular Disorders 2022 22:113
  27. Studies show inconsistent results regarding the impact of CYP2C19 genotype on the pharmacodynamics (PD) and clinical outcomes of ticagrelor. With the implementation of genotype-guided individualized antiplatelet ...

    Authors: Qiufen Xie, Qian Xiang, Zhiyan Liu, Guangyan Mu, Shuang Zhou, Zhuo Zhang, Lingyue Ma, Yanjun Gong, Jie Jiang and Yimin Cui
    Citation: BMC Cardiovascular Disorders 2022 22:111
  28. Prodromal cardiac symptoms are warning signals preceding cardiac disease. Previous studies have shown some gender differences in prodromal symptoms as well as established risk factors for MI. This study aims t...

    Authors: Alice Nyström, Susanne Strömberg, Karin Jansson, Åshild Olsen Faresjö and Tomas Faresjö
    Citation: BMC Cardiovascular Disorders 2022 22:110
  29. Familial hypercholesterolemia (FH) due to a founder variant in Apolipoprotein B (ApoBR3500Q) is reported in 12% of the Pennsylvania Amish community. By studying a cohort of ApoBR3500Q heterozygotes and homozygote...

    Authors: Katie B. Williams, Michael Horst, Millie Young, Christine Pascua, Erik G. Puffenberger, Karlla W. Brigatti, Claudia Gonzaga-Jauregui, Alan R. Shuldiner, Samuel Gidding, Kevin A. Strauss and Devyani Chowdhury
    Citation: BMC Cardiovascular Disorders 2022 22:109
  30. Although cardioplegia is used since the ‘70s of the last century, debate on cardioprotection during cardio-surgical procedures is still actual. The selection of a particular method depends mainly on the prefer...

    Authors: Rafał Nowicki, Mikołaj Berezowski, Julita Kulbacka, Katarzyna Bieżuńska-Kusiak, Marek Jasiński and Jolanta Saczko
    Citation: BMC Cardiovascular Disorders 2022 22:108
  31. Although obesity increases the risk of hypertension, the effect of obesity based on metabolic status on the incidence of hypertension is not known. This study aimed to determine the association between obesity...

    Authors: Behrooz Hamzeh, Yahya Pasdar, Shima Moradi, Mitra Darbandi, Negin Rahmani, Ebrahim Shakiba and Farid Najafi
    Citation: BMC Cardiovascular Disorders 2022 22:106
  32. The real-world studies on recurrent venous thromboembolism (VTE) and bleeding events of non-vitamin K antagonist oral anticoagulants (NOACs) in VTE patients have reported conflicting findings. Our study aimed ...

    Authors: Zhi-Yan Liu, Han-Xu Zhang, Ling-Yue Ma, Guang-Yan Mu, Qiu-Fen Xie, Shuang Zhou, Zi-Ning Wang, Zhe Wang, Kun Hu, Qian Xiang and Yi-Min Cui
    Citation: BMC Cardiovascular Disorders 2022 22:105
  33. The left atrium (LA) is a key player in the pathophysiology of systolic and diastolic heart failure (HF). Speckle tracking derived LA reservoir strain (LASr) can be used as a prognostic surrogate for elevated lef...

    Authors: Sjoerd Bouwmeester, Jonna A. van der Stam, Saskia L. M. van Loon, Natal A. W. van Riel, Arjen-Kars Boer, Lukas R. Dekker, Volkher Scharnhorst and Patrick Houthuizen
    Citation: BMC Cardiovascular Disorders 2022 22:104
  34. Calcified plaque is thought to adversely impact outcomes after percutaneous coronary intervention (PCI). This study sought to evaluate the impact of nodular calcification in patients with acute coronary syndro...

    Authors: Abigail Demuyakor, Sining Hu, Ekaterina Koniaeva, Minghao Liu, Ziqian Weng, Chen Zhao, Xue Feng, Luping He, Yishuo Xu, Ming Zeng, Wei Meng, Yanli Sun, Boling Yi, Zhanqun Gao, Yuhan Qin, Haibo Jia…
    Citation: BMC Cardiovascular Disorders 2022 22:103
  35. Evidence suggests that changes in left ventricular systolic and diastolic functions may affect right atrial (RA) phasic functions. We aimed to evaluate RA phasic functions in the presence of anterior ST-elevat...

    Authors: Mokhtar Eisvand, Reza Mohseni-Badalabadi and Ali Hosseinsabet
    Citation: BMC Cardiovascular Disorders 2022 22:102
  36. To investigate the expression of serum S-adenosylhomocysteine (SAH), interleukin-1β (IL-1β), serum homocysteine (Hcy), tumor necrosis factor-α (TNF-α) and brain derived neurotrophic factor (BDNF) in coronary h...

    Authors: You Wu, Lin Wang, Yu Zhan, Zhixin Zhang, Dan Chen, Yang Xiang and Cui Xie
    Citation: BMC Cardiovascular Disorders 2022 22:101
  37. Atrial fibrillation (AF) is an arrhythmia that impacts deployment and retention rates for United States military pilots. This study aims to characterize United States active duty (AD) pilots with AF and review...

    Authors: Andrea N. Keithler, Andrew S. Wilson, Alexander Yuan, Jose M. Sosa and Kelvin N. V. Bush
    Citation: BMC Cardiovascular Disorders 2022 22:100
  38. The role of the dysfunction of left atrium in the occurrence and development of cardiovascular disease has been gradually recognized. We aim to compare the impact on left atrial (LA) function between patients ...

    Authors: Di Zhou, Wenjing Yang, Yingxia Yang, Gang Yin, Shuang Li, Baiyan Zhuang, Jing Xu, Jian He, Weichun Wu, Yong Jiang, Xiaoxin Sun, Yining Wang, Arlene Sirajuddin, Shihua Zhao and Minjie Lu
    Citation: BMC Cardiovascular Disorders 2022 22:99
  39. The aim of this study was to evaluate the safety and efficacy of zero-fluoroscopy (ZF) catheter ablation (CA) for supraventricular tachycardias (SVT).

    Authors: Tine Prolič Kalinšek, Jernej Šorli, Matevž Jan, Matjaž Šinkovec, Bor Antolič, Luka Klemen, David Žižek and Andrej Pernat
    Citation: BMC Cardiovascular Disorders 2022 22:98
  40. The aim of the present study was to investigate the efficacy of recombinant human endostatin (ES) (rh-ES) combined with radiation on rat cardiomyocyte apoptosis and the regulatory mechanism of transforming gro...

    Authors: Weiwei Ouyang, Shimei Fu, Xing Zhao, Shengfa Su, Jun Zhang, Daxian Luo, Lina Liu, Wenjin Ding, Dongdong Cao, Likun Liu, Zhixu He and Bing Lu
    Citation: BMC Cardiovascular Disorders 2022 22:97
  41. It is unclear whether genetic variants identified from single nucleotide polymorphisms (SNPs) strongly associated with coronary heart disease (CHD) in genome-wide association studies (GWAS), or a genetic risk ...

    Authors: P. L. Thompson, J. Hui, J. Beilby, L. J. Palmer, G. F. Watts, M. J. West, A. Kirby, S. Marschner, R. J. Simes, D. R. Sullivan, H. D. White, R. Stewart and A. M. Tonkin
    Citation: BMC Cardiovascular Disorders 2022 22:96
  42. Mesenchymal stem cell-derived exosomes (MSC-EXO) have emerged as novel therapeutic strategies for myocardial infarction (MI). However, many questions remain untouched and unanswered regarding their roles in my...

    Authors: Wei Jiao, Jie Hao, Yanan Xie, Mingjie Meng and Weinian Gao
    Citation: BMC Cardiovascular Disorders 2022 22:95
  43. Despite surgical advances, acute type A aortic dissection remains a life-threatening disease with high mortality and morbidity. Tracheostomy is usually used for patients who need prolonged mechanical ventilati...

    Authors: Dashuai Wang, Su Wang, Yu Song, Hongfei Wang, Anchen Zhang, Long Wu, Xiaofan Huang, Ping Ye and Xinling Du
    Citation: BMC Cardiovascular Disorders 2022 22:94
  44. Severe acute respiratory coronavirus-2 (SARS-Co-2) is the causative agent of coronavirus disease-2019 (COVID-19). COVID-19 is a disease with highly variable phenotypes, being asymptomatic in most patients. In ...

    Authors: Ismaheel O. Lawal, Mankgopo M. Kgatle, Kgomotso Mokoala, Abubakar Farate and Mike M. Sathekge
    Citation: BMC Cardiovascular Disorders 2022 22:93
  45. Genetic factors along with inadequate lifestyle habits are associated with the development of cardiometabolic alterations. Thus, the present study aimed to examine the role of sedentary behavior on the relatio...

    Authors: Ana Paula Sehn, Caroline Brand, João Francisco de Castro Silveira, Lars Bo Andersen, Anelise Reis Gaya, Pâmela Ferreira Todendi, Andréia Rosane de Moura Valim and Cézane Priscila Reuter
    Citation: BMC Cardiovascular Disorders 2022 22:92
  46. The purpose of this study was to investigate the variables that significantly associated with the quality of life in people with heart failure, and particularly, to identify the association between self-manage...

    Authors: Eui-Young Choi, Jin-Sun Park, Deulle Min, Hye Sun Lee and Jeong-Ah Ahn
    Citation: BMC Cardiovascular Disorders 2022 22:90

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