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  1. Whipple’s disease is a clinically relevant multi-system disorder that is often undiagnosed given its elusive nature. We present an atypical case of Whipple’s disease involving pan-valvular endocarditis and con...

    Authors: Christina S. Thornton, Yinong Wang, Martin Köebel, Kathryn Bernard, Tamara Burdz, Andrew Maitland, Jose G. Ferraz, Paul L. Beck and Andre Ferland

    Citation: BMC Cardiovascular Disorders 2019 19:312

    Content type: Case report

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  2. The most significant manifestation of heart failure is exercise intolerance. This systematic review and meta-analysis was performed to investigate whether dipeptidyl peptidase-4 (DPP-4) inhibitors or glucagon-lik...

    Authors: Chengcong Chen, Ying Huang, Yongmei Zeng, Xiyan Lu and Guoqing Dong

    Citation: BMC Cardiovascular Disorders 2019 19:311

    Content type: Research article

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  3. Coronary artery disease (CAD) and plasma lipid levels are highly correlated, indicating the presence of common pathways between them. Nevertheless, the molecular pathways underlying the pathogenic comorbiditie...

    Authors: Liuying Chen, Yinghao Yao, Chaolun Jin, Shen Wu, Qiang Liu, Jingjing Li, Yunlong Ma, Yizhou Xu and Yigang Zhong

    Citation: BMC Cardiovascular Disorders 2019 19:310

    Content type: Research article

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  4. Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Due to increased CAD risk factors in Saudi Arabia, research on more feasible and predictive biomarkers is needed. We aimed t...

    Authors: Mohammed Ewid, Hossam Sherif, Syed Muhammad Baqui Billah, Nazmus Saquib, Wael AlEnazy, Omer Ragab, Saed Enabi, Tawfik Rajab, Zaki Awad and Rami Abazid

    Citation: BMC Cardiovascular Disorders 2019 19:309

    Content type: Research article

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  5. The optimal level of heart rate (HR) control in patients with atrial fibrillation (AF) is unknown. To assess the effect of rate control on cardiopulmonary exercise capacity and quality of life (QoL) in permane...

    Authors: Fei She, Yuan Ma, Yi Li, Lei Li, Weixian Xu, Hongyan Wang and Ming Cui

    Citation: BMC Cardiovascular Disorders 2019 19:308

    Content type: Research article

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  6. Resting heart rate (RHR) is an obtainable, inexpensive, non-invasive test, readily available on any medical document. RHR has been established as a risk factor for cardiovascular morbidity, is related to other...

    Authors: Michal Ehrenwald, Asaf Wasserman, Shani Shenhar-Tsarfaty, David Zeltser, Limor Friedensohn, Itzhak Shapira, Shlomo Berliner and Ori Rogowski

    Citation: BMC Cardiovascular Disorders 2019 19:307

    Content type: Research article

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  7. Calcific aortic valve disease (CAVD) is an atheroinflammatory process; finally it leads to progressive calcification of the valve. There is no effective pharmacological treatment for CAVD and many of the under...

    Authors: Jonna Weisell, Pauli Ohukainen, Juha Näpänkangas, Steffen Ohlmeier, Ulrich Bergmann, Tuomas Peltonen, Panu Taskinen, Heikki Ruskoaho and Jaana Rysä

    Citation: BMC Cardiovascular Disorders 2019 19:306

    Content type: Research article

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  8. Coronary artery spasm (CAS) is an underdiagnosed disease especially in heart transplant patients, and in those patients the etiology and pathophysiology remain largely unknown, although it has been associated ...

    Authors: M. Pagnoni, J. Regamey, J. Adjedj, G. Rogati, O. Muller and P. Tozzi

    Citation: BMC Cardiovascular Disorders 2019 19:305

    Content type: Case report

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  9. Adverse childhood experiences (ACEs) are associated with risk of poor adult health, including cardiometabolic diseases. Little is known about the correlates of ACEs for adults who have already developed cardio...

    Authors: Robert G. Maunder, David W. Tannenbaum, Joanne A. Permaul, Melissa Nutik, Cleo Haber, Mira Mitri, Daniela Costantini and Jonathan J. Hunter

    Citation: BMC Cardiovascular Disorders 2019 19:304

    Content type: Research article

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  10. Due to epidemiological transitions, Sub-Saharan Africa is facing a growing burden of non-communicable diseases, including cardiovascular diseases (CVDs). Among their risk factors, hypertension is a major deter...

    Authors: Ileana Desormais, Salimanou Ariyoh Amidou, Yessito Corine Houehanou, Stephan Dismand Houinato, Gwladys Nadia Gbagouidi, Pierre Marie Preux, Victor Aboyans and Philippe Lacroix

    Citation: BMC Cardiovascular Disorders 2019 19:303

    Content type: Research article

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  11. Endomyocardial fibrosis (EMF) represents the most common cause of restrictive cardiomyopathy worldwide. Despite a high prevalence in tropical regions, it occasionally occurs in patients who have never visited ...

    Authors: Gernot Wagner, Markus Haumer, Gerhard Poelzl, Dominik Wiedemann, Andreas Kliegel, Robert Ullrich, Gerald Gartlehner, Andreas Zuckermann, Ludwig Müller, Harald Mayr and Deddo Moertl

    Citation: BMC Cardiovascular Disorders 2019 19:302

    Content type: Case report

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  12. Cardiovascular disease has become a serious public health problem in recent years in China. The aim of the study was to examine sex differences in cardiovascular risk factors and 10-year ischemic cardiovascula...

    Authors: Lihong Yang, Anne F. Fish, Yuanyuan Zhu, Xiaodan Yuan, Jianing Li, Xiaoyun Wang, Li Yuan, Zhumin Jia, Chao Liu, Yunchen Xu and Qingqing Lou

    Citation: BMC Cardiovascular Disorders 2019 19:301

    Content type: Research article

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  13. Most coronary spastic angina patients are responsive to coronary vasodilators therapy, and stent implantation is not recommended for regular use. We reported the angiographic and intravascular ultrasound (IVUS...

    Authors: Haoran Wang, Geng Peng, Yancai Dong and Dongliang Liu

    Citation: BMC Cardiovascular Disorders 2019 19:300

    Content type: Case report

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  14. The optimal dosage for cryoablation of atrial fibrillation (Cryo-AF) is still unknown. To evaluate the efficacy of an individualized freeze duration, we compared the clinical outcome of patients treated with a...

    Authors: Jun Ding, Jing Xu, Wei Ma, Bingwei Chen, Peigen Yang, Yu Qi, Shan Sun and Aijuan Cheng

    Citation: BMC Cardiovascular Disorders 2019 19:299

    Content type: Research article

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  15. Patients with some mutations in the lamin A/C (LMNA) gene are characterized by the presence of dilated cardiomyopathy (DCM), conduction abnormalities, ventricular tachyarrhythmias (VT), and sudden cardiac death (...

    Authors: Tetsuro Yokokawa, Shohei Ichimura, Naoko Hijioka, Takashi Kaneshiro, Akiomi Yoshihisa, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Osamu Suzuki, Seiko Ohno, Takeshi Aiba, Hiroshi Ohtani and Yasuchika Takeishi

    Citation: BMC Cardiovascular Disorders 2019 19:298

    Content type: Case report

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  16. Blood glucose (BG) is a risk factor of adverse prognosis in non-diabetic patients in several conditions. However, a limited number of studies were performed to explore the relationship between postoperative BG...

    Authors: Wan-zi Hong, Yu Wang, Hongjiao Yu, Xue-biao Wei, Danqing Yu, Chun-xiang Zhang, Ning Tan and Lei Jiang

    Citation: BMC Cardiovascular Disorders 2019 19:297

    Content type: Research article

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  17. Coronary artery ectasia (CAE) is an uncommon finding in patients undergoing coronary angiography and acute myocardial infarction is an extremely uncommon condition in the presence of coronary artery ectasia. T...

    Authors: Mohammad Rafi Noori, Bo Zhang and Lifei Pan

    Citation: BMC Cardiovascular Disorders 2019 19:296

    Content type: Case report

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  18. Late gadolinium enhancement (LGE) using cardiac magnetic resonance (CMR) characterizes myocardial disease and predicts an adverse cardiovascular (CV) prognosis. Myocardial abnormalities, are present in early c...

    Authors: Anna M. Price, Manvir K. Hayer, Ravi Vijapurapu, Saad A. Fyyaz, William E. Moody, Charles J. Ferro, Jonathan N. Townend, Richard P. Steeds and Nicola C. Edwards

    Citation: BMC Cardiovascular Disorders 2019 19:295

    Content type: Research article

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  19. Postoperative atrial fibrillation occurs in up to 30% of patients after coronary artery bypass graft (CABG) and its cause is unknown. The aim of the study was to evaluate whether concentration of resistin in s...

    Authors: Maciej Rachwalik, Marta Obremska, Dorota Zyśko, Małgorzata Matusiewicz, Krzysztof Ściborski and Marek Jasiński

    Citation: BMC Cardiovascular Disorders 2019 19:294

    Content type: Research article

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  20. Coronary heart disease (CHD) is the most common cause of mortality globally, yet mitochondrial genetic mutations associated with CHD development remain incompletely understood.

    Authors: Zhenxiao Zhang, Mingyang Liu, Jianshuai He, Xiaotian Zhang, Yuehua Chen and Hui Li

    Citation: BMC Cardiovascular Disorders 2019 19:293

    Content type: Research article

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  21. Recent scientific reports have brought into light a new concept of goal-directed perfusion (GDP) that aims to recreate physiological conditions in which the risk of end-organ malperfusion is minimalized. The a...

    Authors: Marceli Lukaszewski, Rafal Lukaszewski, Kinga Kosiorowska and Marek Jasinski

    Citation: BMC Cardiovascular Disorders 2019 19:292

    Content type: Research article

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  22. Congenital heart diseases (CHD) are among the most common congenital malformations. It is estimated that the incidence of CHD is constant worldwide, but data are rare for most African countries including Tanza...

    Authors: Antke Zuechner, Tumaini Mhada, Naizihijwa G. Majani, Godwin G. Sharau, William Mahalu and Matthias W. Freund

    Citation: BMC Cardiovascular Disorders 2019 19:291

    Content type: Research article

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  23. Psychological factors, such as self-efficacy, are important in understanding the progress and management of coronary heart disease (CHD), and how patients make lifestyle modifications to compensate for the dis...

    Authors: Aya Barham, Reem Ibraheem and Sa’ed H. Zyoud

    Citation: BMC Cardiovascular Disorders 2019 19:290

    Content type: Research article

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  24. Coronary slow flow phenomenon (CSFP) is an angiographic entity characterized by delayed coronary opacification in absence of evident obstructive lesion in the epicardial coronary artery. However, whether patie...

    Authors: Yonghuai Wang, Jinyang Li, Shuang Liu, Lixin Mu, Guangyuan Li, Hang Yu, Jun Yang and Chunyan Ma

    Citation: BMC Cardiovascular Disorders 2019 19:288

    Content type: Research article

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  25. Hepatocellular carcinoma (HCC) with right ventricle metastasis without inferior vena cava and right atrium involvement is very rare and the prognosis of HCC with RV metastasis is generally poor. The mass in th...

    Authors: Xin-tong Zhang, Ying Li, Si-hua Ren, Wei-dong Ren, Guang Song, Yang-jie Xiao, Fei-fei Sun, Lu Sun, Xiang-hong Yang and Xue-ying Tan

    Citation: BMC Cardiovascular Disorders 2019 19:287

    Content type: Case report

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  26. Patients after aortic coarctation (CoA) repair show impaired aortic bioelasticity and altered left ventricular (LV) mechanics, predisposing diastolic dysfunction. Our purpose was to assess aortic bioelasticity...

    Authors: Theresa Pieper, Heiner Latus, Dietmar Schranz, Joachim Kreuder, Bettina Reich, Kerstin Gummel, Helge Hudel and Inga Voges

    Citation: BMC Cardiovascular Disorders 2019 19:286

    Content type: Research article

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  27. Complete and simplified Selvester QRS score have been proposed as valuable clinical tool for estimating myocardial damage in patients with ST-elevation myocardial infarction (STEMI). We sought to comprehensive...

    Authors: Christina Tiller, Martin Reindl, Sebastian Johannes Reinstadler, Magdalena Holzknecht, Michael Schreinlechner, Alexander Peherstorfer, Nicolas Hein, Ivan Lechner, Agnes Mayr, Gert Klug and Bernhard Metzler

    Citation: BMC Cardiovascular Disorders 2019 19:285

    Content type: Research article

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  28. AAA is a disease affecting predominantly male patients ≥65 years and its dreaded complications such as rupture led to population-based screening programs as preventive measure. Nonetheless, the supposed preval...

    Authors: Anna Hohneck, Michael Keese, Gerhard Ruemenapf, Klaus Amendt, Hannelore Muertz, Katharina Janda, Ibrahim Akin, Martin Borggrefe and Martin Sigl

    Citation: BMC Cardiovascular Disorders 2019 19:284

    Content type: Research article

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  29. Acute aortic dissection (AAD) is a life-threatening disorder in vascular surgery with a high early mortality. Serum amyloid A (SAA) is a kind of acute-phase protein with a rapid diagnostic value in other disea...

    Authors: Yuchen He, Changcheng Ma, Jia Xing, Shiyue Wang, Chao Ji, Yanshuo Han and Jian Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:282

    Content type: Research article

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  30. Advanced echocardiography techniques such as speckle tracking imaging are sensitive diagnostic tools frequently used in various clinical and scientific scenarios. Importantly, imperfect reproducibility and dep...

    Authors: Kai O. Hensel

    Citation: BMC Cardiovascular Disorders 2019 19:281

    Content type: Commentary

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  31. In spite of the important role of Apolipoprotein-M (ApoM) and Sphingosine-1-Phosphate (S1P) played in atherosclerosis (AS), there was few related research reporting ApoM and S1P complex (ApoM-S1P) on biologica...

    Authors: Yang Liu and Li Tie

    Citation: BMC Cardiovascular Disorders 2019 19:279

    Content type: Research article

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  32. Diabetes mellitus (DM) has been demonstrated to be a strong risk factor for development and perpetuation of atrial fibrillation (AF). However, how DM and glycemic control affect the pathogenesis of AF has not ...

    Authors: Qing Wang, Jing Wang, Pei Wang, Liaoyuan Wang, Lanting Jia, Xinyu Ling, Wang Xi, Jie Min, Hua Shen, Jian Xiao, Jinxiang Yuan and Zhinong Wang

    Citation: BMC Cardiovascular Disorders 2019 19:278

    Content type: Research article

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  33. Evidences regarding the associations between maternal upper respiratory tract infection/influenza during pregnancy and the risk of congenital heart disease (CHD) is still controversial. This study was specific...

    Authors: Y. Q. Xia, K. N. Zhao, A. D. Zhao, J. Z. Zhu, H. F. Hong, Y. L. Wang and S. H. Li

    Citation: BMC Cardiovascular Disorders 2019 19:277

    Content type: Research article

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  34. Corrected QT (QTc) interval has been correlated with total and CVD mortality. Although much is known about the relation between prolonged QTc interval and clinical outcome, there is no information on the preva...

    Authors: Qun Ma, Zhao Li, Xiaofan Guo, Liang Guo, Shasha Yu, Hongmei Yang, Lu Zou, Liqiang Zheng, Guowei Pan, Yonghong Zhang and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2019 19:276

    Content type: Research article

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  35. Korea has seen a rapid increase in the use of percutaneous coronary intervention (PCI) with the ratio of PCI to coronary artery bypass graft (CABG) the highest in the world. This study was performed to examine...

    Authors: Agnus M. Kim, Jong Heon Park, Seongcheol Cho, Sungchan Kang, Tae Ho Yoon and Yoon Kim

    Citation: BMC Cardiovascular Disorders 2019 19:275

    Content type: Research article

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  36. Cardiac rehabilitation (CR) uptake and adherence remain sub-optimal despite the apparent health benefits of modifying healthy behavior and slowing disease progression. eHealth is the use of information and com...

    Authors: Jing Jing Su and Doris Sau Fung Yu

    Citation: BMC Cardiovascular Disorders 2019 19:274

    Content type: Study protocol

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  37. The interventional treatment of chronic total occlusion (CTO) with stent fracture as well as severe calcification was extremely difficult and no effective technique has been reported.

    Authors: Yajun Xue, Boda Zhou, Weimin Wang, Guobin Miao, Ou Zhang, Jie Zhou, Yu Geng, Yanlong Zhai, Chunhui Ren and Ping Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:273

    Content type: Case report

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  38. Coronary heart disease is related to sudden death caused by multi-factors and a major threat to human health.This study explores the role of OX40L and ICAM-1 in the stability of coronary plaques and their rela...

    Authors: Yu Wang, Xiaoyu Sun, Bing Xia, Cuiyun Le, Zhu Li, Jie Wang, Jiang Huang, Jiawen Wang and Changwu Wan

    Citation: BMC Cardiovascular Disorders 2019 19:272

    Content type: Research article

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  39. Cardiovascular disease including ST elevation myocardial infarction (STEMI) is increasing and the leading cause of death in China. There has been limited data available to characterize STEMI management and out...

    Authors: You Zhang, Shan Wang, Shuyan Yang, Shanshan Yin, Qianqian Cheng, Muwei Li, Datun Qi, Xianpei Wang, Zhongyu Zhu, Luosha Zhao, Dayi Hu and Chuanyu Gao

    Citation: BMC Cardiovascular Disorders 2019 19:271

    Content type: Study protocol

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  40. To estimate the prevalence of elevated blood glucose level (EBG, including type 2 diabetes mellitus and impaired fasting glucose), and its association with non-valvular atrial fibrillation (NVAF) in Guangzhou,...

    Authors: Lu Fu, Hai Deng, Wei-dong Lin, Shang-fei He, Fang-zhou Liu, Yang Liu, Xian-zhang Zhan, Xian-hong Fang, Hong-tao Liao, Wei Wei, Zi-li Liao, Li-hong Tang, Zu-yi Fu, Mu-rui Zheng, Shu-lin Wu and Yu-mei Xue

    Citation: BMC Cardiovascular Disorders 2019 19:270

    Content type: Research article

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  41. Several studies have reported on atrial fibrillation (AF) outcomes, including thromboembolism in patients with paroxysmal and non-paroxysmal AF; however the findings still remain controversial on whether risks...

    Authors: Ying Wang, Chang-Sheng Ma, Xin Du, Liu He, Jie Li, Guo-Hong Wang, Dan Wen, Jian-Zeng Dong, Jian-Hong Pan and Gregory Y. H. Lip

    Citation: BMC Cardiovascular Disorders 2019 19:283

    Content type: Research article

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  42. Hypertension and arterial vasculopathy may be mutual causes and effects. It is unknown whether carotid intima-media thickness (cIMT) is reliably predictive of the presence of newly developed hypertension in th...

    Authors: Long Zhang, Fangfang Fan, Litong Qi, Jia Jia, Ying Yang, Jianping Li and Yan Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:269

    Content type: Research article

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  43. Cardiovascular disease (CVD) is the primary cause of death worldwide, accounting for 31.0% of all deaths and more than 18 million deaths annually. The 2008 World Health Report indicated that 144 (35%) of the 4...

    Authors: Ranya A. Ghamri, Nada S. Alzahrani, Amal M. Alharthi, Hana J. Gadah, Bayan G. Badoghaish and Azzah A. Alzahrani

    Citation: BMC Cardiovascular Disorders 2019 19:268

    Content type: Research article

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  44. Left ventricular global longitudinal strain (GLS) with cardiovascular magnetic resonance (CMR) is an important prognostic biomarker. Its everyday clinical use is limited due to methodological and postprocessin...

    Authors: Robert Heinke, Faraz Pathan, Melanie Le, Tommaso D’Angelo, Lea Winau, Christophe Arendt, Thomas J. Vogl, Andreas Zeiher, Eike Nagel and Valentina O. Puntmann

    Citation: BMC Cardiovascular Disorders 2019 19:267

    Content type: Research article

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  45. Although perioperative care during heart surgery has improved considerably, the rate of postoperative complications has remained stable. It has not been concluded how to better apply grip strength to clinical,...

    Authors: Liyuan Fu, Yuanyuan Zhang, Bohan Shao, Xiangjing Liu, Bo Yuan, Zhengqing Wang, Tienan Chen, Zhigang Liu, Xiaocheng Liu and Qi Guo

    Citation: BMC Cardiovascular Disorders 2019 19:266

    Content type: Research article

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  46. Coronary artery disease (CAD), including acute myocardial infarction (AMI), is a common complex disease. Although a great number of genetic loci and variants for CAD have been identified, genetic causes and un...

    Authors: Shuai Wang, Jie Zhang, Xiaohui He, Yexin Zhang, Jing Chen, Qiang Su, Shuchao Pang, Shufang Zhang, Yinghua Cui and Bo Yan

    Citation: BMC Cardiovascular Disorders 2019 19:265

    Content type: Research article

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  47. After publication of the original article [1], we were notified that the name of the software mentioned in the Background section is TAONET and not Tao Net.

    Authors: Bárbara Menéndez-Jándula, José Antonio García-Erce, Clara Zazo and Luis Larrad-Mur

    Citation: BMC Cardiovascular Disorders 2019 19:263

    Content type: Correction

    Published on:

    The original article was published in BMC Cardiovascular Disorders 2019 19:186