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  1. Pregnancy-associated Venous thromboembolism (VTE) is one of the most common causes of maternal morbidity and mortality in developed countries. In this study, we aimed to systematically review and critical appr...

    Authors: Jie Zheng, Qinchang Chen, Jing Fu, Yanling Lu, Tianjun Han and Ping He

    Citation: BMC Cardiovascular Disorders 2019 19:199

    Content type: Research article

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  2. Premature infants may present with damage to the autonomic nervous system (ANS), which may be related to poorer neurological development. Among the techniques used to evaluate the ANS, heart rate variability (...

    Authors: Luiz Fernando Martins de Souza Filho, Jordana Campos Martins de Oliveira, Mayara Kelly Alves Ribeiro, Marcelo Cozac Moura, Nelson David Fernandes, Rafael Dias de Sousa, Gustavo Rodrigues Pedrino and Ana Cristina Silva Rebelo

    Citation: BMC Cardiovascular Disorders 2019 19:198

    Content type: Research article

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  3. Cardiac pacing is a growing activity in Sub-Saharan Africa. There is little data on the characteristics of this interventional treatment in our regions. The goal was to evaluate the results of cardiac pacing i...

    Authors: Adama Kane, Simon Antoine Sarr, Juliette Valerie Danièle Ndobo, Alioune Tabane, Kana Babaka, Fatou Aw, Malick Bodian, Serigne Mor Beye, Momar Dioum, Aliou Alassane Ngaidé, Mouhamadou Bamba Ndiaye, Alassane Mbaye, Maboury Diao, Abdoul Kane and Serigne Abdou BA

    Citation: BMC Cardiovascular Disorders 2019 19:197

    Content type: Research article

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  4. Left atrial appendage closure is increasingly used. LAA closure procedures can rarely be complicated by device embolization, typically towards the aorta. In this case report, we describe the successful percuta...

    Authors: Manik Chopra, Yam-Hong Wong, Lars Søndergaard and Ole De Backer

    Citation: BMC Cardiovascular Disorders 2019 19:196

    Content type: Case report

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  5. In patients with cardiac resynchronization therapy (CRT), atrial fibrillation (AF) is associated with an unfavorable outcome and may cause loss of biventricular pacing (BivP). An effective delivery of BivP of ...

    Authors: Jonatan Jacobsson, Christian Reitan, Jonas Carlson, Rasmus Borgquist and Pyotr G. Platonov

    Citation: BMC Cardiovascular Disorders 2019 19:195

    Content type: Research article

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  6. Mineralocorticoid receptor antagonists (MRA) are an underutilized therapy for heart failure with a reduced ejection fraction (HFrEF), but the current impact of hospitalization on MRA use is not well characteri...

    Authors: Matthew S. Durstenfeld, Stuart D. Katz, Hannah Park and Saul Blecker

    Citation: BMC Cardiovascular Disorders 2019 19:194

    Content type: Research article

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  7. This study aimed to investigate the effect of long non-coding RNA nuclear enriched abundant transcript 1 (lnc-NEAT1) on cell proliferation and apoptosis in myocardial ischemia/reperfusion (I/R) injury cells, a...

    Authors: Lingyun Ren, Shanshan Chen, Wei Liu, Pan Hou, Wei Sun and Hong Yan

    Citation: BMC Cardiovascular Disorders 2019 19:192

    Content type: Research article

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  8. Swallow or deglutition syncope is an unusual type of neurally-mediated syncope associated with life-threatening bradyarrhythmia and hypotension. It is a difficult condition to diagnose with commonly delayed di...

    Authors: Kelvin Shenq Woei Siew, Maw Pin Tan, Ida Normiha Hilmi and Alexander Loch

    Citation: BMC Cardiovascular Disorders 2019 19:191

    Content type: Case report

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  9. Development of instruments capable of detecting early stage vascular disease has increased interest in employing arterial stiffness (e.g. pulse wave velocity (PWV), augmentation index (AIx)) and endothelial dy...

    Authors: Raissa Perrault, Alexander Omelchenko, Carla G. Taylor and Peter Zahradka

    Citation: BMC Cardiovascular Disorders 2019 19:190

    Content type: Research article

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  10. Coronary artery bypass graft (CABG) surgery is an effective therapeutic strategy for coronary heart disease (CHD). Myocardial longitudinal strain echocardiography with 2D speckle tracking could obtain ventricu...

    Authors: Anna Gozdzik, Krzysztof Letachowicz, Barbara Barteczko Grajek, Tomasz Plonek, Marta Obremska, Marek Jasinski and Waldemar Gozdzik

    Citation: BMC Cardiovascular Disorders 2019 19:189

    Content type: Research article

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  11. Coronary artery aneurysm (CAA) is a rare disease, and there are limited data on prescribing patterns for CAA. The aim of our study was to investigate prescribing patterns for CAA in Taiwan via the National Hea...

    Authors: Chun-Hui Lu, Chih-Wun Fang, Hao-Ming Chen, Yi-Ping Fang, Chein-Tang Fang, Yaw-Bin Huang, Chung-Yu Chen, Kuang-Ming Liao and Shu-Chuan Jennifer Yeh

    Citation: BMC Cardiovascular Disorders 2019 19:188

    Content type: Research article

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  12. It is uncertain whether the coronary lesion with intermediate stenosis is more likely to cause cardiovascular events than a normal or minimal lesion. We conducted a single-center, prospective cohort study to i...

    Authors: Young Hoon Seo, Yong-Kyun Kim, In Geol Song, Ki-Hong Kim, Taek-Geun Kwon and Jang-Ho Bae

    Citation: BMC Cardiovascular Disorders 2019 19:187

    Content type: Research article

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  13. The patient self-management (PSM) is an effective approach for controlling the international normalized ratio, INR, within the therapeutic range. Nevertheless, most of the literature derives from randomized cl...

    Authors: Bárbara Menéndez-Jándula, José Antonio García-Erce, Clara Zazo and Luis Larrad-Mur

    Citation: BMC Cardiovascular Disorders 2019 19:186

    Content type: Research article

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2019 19:263

  14. It has been indicated that Angiotensin-Converting Enzyme Insertion/Deletion (ACE I/D) polymorphism (rs4646994) could be regarded as a genetic factor that raises the risk of CAD through its impact on the activi...

    Authors: Negar Nouryazdan, Glavizh Adibhesami, Mehdi Birjandi, Rouhollah Heydari, Banafsheh Yalameha and Gholamreza Shahsavari

    Citation: BMC Cardiovascular Disorders 2019 19:184

    Content type: Research article

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  15. The development of novel oral anticoagulants (NOACs) has changed the landscape of non-valvular atrial fibrillation (NVAF) management. In this study, the effectiveness and the safety of several NOACs were evalu...

    Authors: Jianchao Zhang, Junnan Tang, Xiaolin Cui, Bo Wang, Mengsen Bu, Yan Bai, Kai Wang, Jiacheng Guo, Deliang Shen and Jinying Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:182

    Content type: Research article

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  16. Considering vital role of renal arteries in many surgical procedures, diameter of renal arteries seems to be an important measure of kidney perfusion. In this study, we analyzed a new parameter, renal-aortic r...

    Authors: Marcin Majos, Michał Polguj, Ludomir Stefańczyk, Magdalena Derlatka-Kochel, Mariusz Wachowski and Agata Majos

    Citation: BMC Cardiovascular Disorders 2019 19:181

    Content type: Research article

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  17. Cardiovascular (CV) diseases including heart failure are the leading causes of morbidity, with age being the primary risk factor. The combination of age-related organic functional impairment and reduced physic...

    Authors: Jonathan Wagner, Raphael Knaier, Denis Infanger, Konstantin Arbeev, Matthias Briel, Thomas Dieterle, Henner Hanssen, Oliver Faude, Ralf Roth, Timo Hinrichs and Arno Schmidt-Trucksäss

    Citation: BMC Cardiovascular Disorders 2019 19:180

    Content type: Study protocol

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  18. Cardiac haemangiomas are exceptionally rare. They are usually solitary growths. Cardiac haemangiomas can be classified as capillary, cavernous, or arteriovenous in nature. They can occur in any chambers of the...

    Authors: Mahmoud Yousef Ibrahim Abuharb, Xiao Ming Bian and Jian He

    Citation: BMC Cardiovascular Disorders 2019 19:179

    Content type: Case report

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  19. Atrial fibrillation (AF) significantly increases the risk of ischemic stroke depending on various risk factors. The CHA2DS2-VASc score is used widely to improve stratification of AF-related stroke to identify for...

    Authors: Chen-Di Cheng, Xiang Gu, Hong-Xiao Li, Ruo-Yu Duan, Lei Sun, Yi Zhang, Zheng-Yu Bao, Jian-Hua Shen, Fu-Kun Chen and Ye Zhu

    Citation: BMC Cardiovascular Disorders 2019 19:178

    Content type: Case report

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  20. With aging of the population, screening and prevention health programs for blood donors will increasingly be a priority. We aimed at: assessing the 10 year-cardiovascular disease (CVD) risk in blood donors, ac...

    Authors: Francesco Vadini, Francesca Santilli, Giuseppe Casalini, Mario dell’Isola, Ornella Iuliani, Damiano D’Ardes, Luisa Lattanzio, Marta Di Nicola, Giancarlo Di Iorio and Patrizia Accorsi

    Citation: BMC Cardiovascular Disorders 2019 19:177

    Content type: Research article

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  21. It is well known that the genotype of ALDH2 is associated with coronary artery disease (CAD), and in-stent restenosis (ISR) is a primary complication of percutaneous coronary intervention (PCI), a primary recomme...

    Authors: Lizhi Lv, Weijie Ye, Peiyuan Song, Yubin Chen, Jing Yang, Congmin Zhang, Xiaoping Chen and Fanyan Luo

    Citation: BMC Cardiovascular Disorders 2019 19:176

    Content type: Research article

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  22. In-stent restenosis remains an unresolved issue. Inflammation plays a pivotal role in the process of in-stent restenosis. Significant and positive associations were found between red blood cell distribution width...

    Authors: Ning Geng, Guangsheng Su, Shaojun Wang, Deling Zou, Wenyue Pang and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2019 19:175

    Content type: Research article

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  23. We aimed to determine the mutation yield and clinical applicability of “molecular autopsy” following sudden arrhythmic death syndrome (SADS) by validating and utilizing low-cost high-throughput technologies: F...

    Authors: Hariharan Raju, James S. Ware, Jonathan R. Skinner, Paula L. Hedley, Gavin Arno, Donald R. Love, Christian van der Werf, Jacob Tfelt-Hansen, Bo Gregers Winkel, Marta C. Cohen, Xinzhong Li, Shibu John, Sanjay Sharma, Steve Jeffery, Arthur A. M. Wilde, Michael Christiansen…

    Citation: BMC Cardiovascular Disorders 2019 19:174

    Content type: Research article

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  24. An estimated 55% of older adults in Africa have systemic hypertension, a major risk factor for stroke, heart failure and dementia in the region. The risk factors associated with hypertension in this population...

    Authors: William Kofi Bosu, Justice Moses Kwaku Aheto, Eugenio Zucchelli and Siobhan Theresa Reilly

    Citation: BMC Cardiovascular Disorders 2019 19:173

    Content type: Research article

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  25. To evaluate the outcomes of transcatheter aortic valve implantation (TAVI) without balloon aortic valvuloplasty (BAV) in a real-world setting through a patient-level meta-analysis.

    Authors: Jannik Ole Ashauer, Nikolaos Bonaros, Markus Kofler, Gerhard Schymik, Christian Butter, Mauro Romano, Vinayak Bapat, Justus Strauch, Holger Schröfel, Andreas Busjahn, Cornelia Deutsch, Peter Bramlage, Jana Kurucova, Martin Thoenes, Stephan Baldus and Tanja K. Rudolph

    Citation: BMC Cardiovascular Disorders 2019 19:172

    Content type: Research article

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  26. Improving clinical practice aimed at controlling hypertension is a pending issue in health systems. One of the methods currently used for this purpose is self blood pressure measurement (SBPM) whose use increa...

    Authors: Arleen De León-Robert, Juan José Gascón-Cánovas, José Joaquín Antón-Botella, Isabel María Hidalgo-García, Carmen López-Alegría, Yoalys Dilvani Pérez-Cabrera and Heidy Merari Campusano-Castellanos

    Citation: BMC Cardiovascular Disorders 2019 19:171

    Content type: Research article

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  27. Aneurysmal subarachnoid hemorrhage is a life- threatening condition with high rate of disability and mortality. Apolipoprotein E (APOE) and Factor XIIIA (F13A) genes are involved in the pathogenetic mechanism of ...

    Authors: S. Arati, G. K. Chetan, M. K. Sibin, Dhananjaya I. Bhat, Vikas Vazhayil and K. V. L. Narasingarao

    Citation: BMC Cardiovascular Disorders 2019 19:170

    Content type: Research article

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  28. Anthracyclines are highly effective anticancer medication prescribed for the treatment of breast cancer. Nevertheless, the use of anthracyclines as chemotherapeutic agents involves a risk for development of ca...

    Authors: Jock Chichaco Kuruc, Armando A. Durant-Archibold, Jorge Motta, K. S. Rao, Barry Trachtenberg, Carlos Ramos, Hongyu Wang, David Gorenstein, Fredrik Vannberg and King Jordan

    Citation: BMC Cardiovascular Disorders 2019 19:169

    Content type: Case report

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  29. The prognostic implication of statin in tolerance (SI) in those with stable CAD remains unclear. We hypothesized that SI is of higher prognostic significance in stable CAD patients with elevated high-sensitive...

    Authors: Jo-Jo Hai, Yuen-Kwun Wong, Chun-Ka Wong, Ka-Chun Un, Pak-Hei Chan, Chung-Wah Siu, Kai-Hang Yiu, Chu-Pak Lau and Hung-Fat Tse

    Citation: BMC Cardiovascular Disorders 2019 19:168

    Content type: Research article

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  30. Autoimmune diseases, such as systemic lupus erythematosus (SLE), are associated with thrombosis and atherosclerosis. Presence of lupus anticoagulant is an independent risk factor for atherosclerotic diseases.

    Authors: Kota Murai, Kenji Sakata, Tadatsugu Gamou, Yoji Nagata, Hayato Tada, Masaya Shimojima, Hirofumi Okada, Kenshi Hayashi and Masa-aki Kawashiri

    Citation: BMC Cardiovascular Disorders 2019 19:167

    Content type: Case report

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  31. Despite of the established effectiveness, the acceptance and adherence of cardiac rehabilitation (CR) remains sub-optimal. Mobile technologies are increasingly used in promoting CR without any firm evidence of...

    Authors: Linqi Xu, Feng Li, Changli Zhou, Jinwei Li, Chengcheng Hong and Qian Tong

    Citation: BMC Cardiovascular Disorders 2019 19:166

    Content type: Research article

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  32. Non-vitamin K antagonist (VKA) oral anticoagulants (NOACs) have substantially improved anticoagulation therapy for prevention of stroke and systemic embolism in patients with atrial fibrillation (AF). The avai...

    Authors: Raffaele De Caterina, Peter Kelly, Pedro Monteiro, Jean Claude Deharo, Carlo de Asmundis, Esteban López-de-Sá, Thomas W. Weiss, Johannes Waltenberger, Jan Steffel, Joris R. de Groot, Pierre Levy, Ameet Bakhai, Wolfgang Zierhut, Petra Laeis, Michael Kerschnitzki, Paul-Egbert Reimitz…

    Citation: BMC Cardiovascular Disorders 2019 19:165

    Content type: Research article

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  33. Microparticles are procoagulant membrane vesicles that play role in endothelium dysfunction pathogenesis and are increased in hypertension, acute/chronic vascular pathological events. Here; we aimed to compare...

    Authors: Hanife Usta Atmaca, Feray Akbas and Hale Aral

    Citation: BMC Cardiovascular Disorders 2019 19:164

    Content type: Research article

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  34. Patients with acute myocardial infarction (AMI) often accompanied by admission hyperglycemia, which usually predicts a poor clinical outcomes for non-diabetes mellitus. Appropriate cut-point to identify high r...

    Authors: Xiao Song Ding, Shan Shan Wu, Hui Chen, Xue Qiao Zhao and Hong Wei Li

    Citation: BMC Cardiovascular Disorders 2019 19:163

    Content type: Research article

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  35. Massive hemoptysis is a life-threatening condition. Massive hemoptysis caused by pulmonary vein stenosis (PVS) after radiofrequency catheter ablation for atrial fibrillation (AF) is rare. However, bilateral lu...

    Authors: Dong Yu, Bing Jie, Ling-Ling Li and Sen Jiang

    Citation: BMC Cardiovascular Disorders 2019 19:162

    Content type: Case report

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  36. Infarct evolution rate and response to acute reperfusion therapy may differ between patients, which is important to consider for accurate management and treatment of patients with ST-elevation myocardial infar...

    Authors: David Nordlund, Henrik Engblom, Jean-Louis Bonnet, Henrik Steen Hansen, Dan Atar, David Erlinge, Ulf Ekelund, Einar Heiberg, Marcus Carlsson and Håkan Arheden

    Citation: BMC Cardiovascular Disorders 2019 19:161

    Content type: Research article

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  37. Contrast-induced nephropathy (CIN) is one of major and serious complications in patients undergoing percutaneous coronary intervention (PCI). It is unknown whether increased urinary adiponectin (UAPN), a sensi...

    Authors: Jun-yi Zhang, Qiong Wang, Ru-tao Wang, Fei Li, He-xiang Cheng, Kun Lian, Yi Liu and Ling Tao

    Citation: BMC Cardiovascular Disorders 2019 19:160

    Content type: Research article

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  38. Non-traumatic chest pain (NTCP) is a common reason for emergency department (ED) attendance in high-income countries, with the primary concern focused on life threatening cardiovascular diseases. There is gene...

    Authors: Amour S. Mohamed, Hendry R. Sawe, Biita Muhanuzi, Nafsa R. Marombwa, Kilalo Mjema and Ellen J. Weber

    Citation: BMC Cardiovascular Disorders 2019 19:158

    Content type: Research article

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  39. Atrial fibrillation (AF) and related atrial tachyarrhythmias (AT), including type I atrial flutter (AFL) are frequently observed in patients with pulmonary hypertension (PH). Their relationship to hemodynamic ...

    Authors: Zdenka Fingrova, Stepan Havranek, David Ambroz, Pavel Jansa and Ales Linhart

    Citation: BMC Cardiovascular Disorders 2019 19:157

    Content type: Research article

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  40. Familial hypercholesterolemia (FH) can lead to premature coronary heart disease. Anticardiolipin antibody may be a contributor for thrombosis. Here, we report an adult with possible FH suffered from premature ...

    Authors: Xin Su, Aqian Wang, Hai Zhu, Hongling Su, Yichao Duan, Shanlian Wu, Min Zhang, Yan Huang, Xing Zhou and Yunshan Cao

    Citation: BMC Cardiovascular Disorders 2019 19:156

    Content type: Case report

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  41. Genetic and environment play a significant role in the etiology of essential hypertension (EH). Recently STK39 rs3754777, ATP2B1 rs2681472 and rs17249754 have been associated with BP variation and hypertension. I...

    Authors: Herman Karim Sombié, Jonas Koudougou Kologo, Daméhan Tchelougou, Serge Yannick Ouédraogo, Abdoul Karim Ouattara, Tegwindé Rebecca Compaoré, Bolni Marius Nagalo, Abel Pegdwendé Sorgho, Issoufou Nagabila, Serge Théophile Soubeïga, Florencia Wendkuuni Djigma, Albert Théophane Yonli, Patrice Zabsonré, Hassanata Millogo and Jacques Simporé

    Citation: BMC Cardiovascular Disorders 2019 19:155

    Content type: Research article

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  42. We investigated changes of cortical thickness and its association with cognitive performance in patients with high-grade carotid artery stenosis without ischemic brain lesions.

    Authors: Alina Nickel, Simon Kessner, Andreas Niebuhr, Julian Schröder, Caroline Malherbe, Felix Fischer, Marlene Heinze, Bastian Cheng, Jens Fiehler, Hans Pinnschmidt, Axel Larena-Avellaneda, Christian Gerloff and Götz Thomalla

    Citation: BMC Cardiovascular Disorders 2019 19:154

    Content type: Research article

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  43. Fatty acid-binding protein 4 (FABP4) (also known as adipocyte FABP or adipocyte P2) is expressed in adipocytes, macrophages, and capillary endothelial cells. Previous studies have shown associations among plas...

    Authors: Chao-Ping Wang, Chia-Chang Hsu, Wei-Chin Hung, Teng-Hung Yu, Cheng-Ching Wu, I-Ting Tsai, Wei-Hua Tang, Fu-Mei Chung, Jer-Yiing Houng, Yau-Jiunn Lee and Yung-Chuan Lu

    Citation: BMC Cardiovascular Disorders 2019 19:153

    Content type: Research article

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  44. Contrast-induced nephropathy (CIN) is common after percutaneous coronary intervention (PCI) and always leads to a poor prognosis. Compared with conventional detection methods, either high-sensitivity C-reactiv...

    Authors: Guoqiang Gu, Xuechao Yuan, Yaqing Zhou, Demin Liu and Wei Cui

    Citation: BMC Cardiovascular Disorders 2019 19:152

    Content type: Research article

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  45. Continuous-flow left ventricular assist devices (LVADs) improve survival and morbidity in patients with stage D heart failure. Management of LVADs for longer durations is necessary in some clinical settings, a...

    Authors: Chie Bujo, Eisuke Amiya, Masaru Hatano, Masaki Tsuji, Hisataka Maki, Yumiko Hosoya, Emi Fujii, Tatsuya Kamon, Toshiya Kojima, Kan Nawata, Osamu Kinoshita, Mitsutoshi Kimura, Minoru Ono and Issei Komuro

    Citation: BMC Cardiovascular Disorders 2019 19:151

    Content type: Case report

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  46. The aim of this study was to investigate the relationship between Talin-1 and stability of carotid atherosclerosis plaque and also find out the role of miRNA, as an upstream regulator, in regulating the expres...

    Authors: Xiaolong Wei, Yudong Sun, Tonglei Han, Jiang Zhu, Yongfu Xie, Shiying Wang, Yani Wu, Yinxing Fan, Xiuli Sun, Jian Zhou, Zhiqing Zhao and Zaiping Jing

    Citation: BMC Cardiovascular Disorders 2019 19:149

    Content type: Research article

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