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  1. Tinnitus is a common auditory symptom. Dysfunction in the autonomic nervous system (ANS) is an essential part of the etiopathogenesis of tinnitus. ANS regulates heart rate and heart rhythm and can lead to vent...

    Authors: Hakan Kaya, Arif Suner, Mehtap Koparal, S. Cem Yucetas and Safiye Kafadar
    Citation: BMC Cardiovascular Disorders 2021 21:415
  2. This study aimed to investigate the clinical features and prognosis of diabetes and myocardial injury in patients admitted to the emergency department.

    Authors: Gil Bonet, Anna Carrasquer, Óscar M. Peiró, Raul Sanchez-Gimenez, Nisha Lal-Trehan, Victor del-Moral-Ronda, Isabel Fort-Gallifa and Alfredo Bardají
    Citation: BMC Cardiovascular Disorders 2021 21:414
  3. The bicuspid aortic valve (BAV) is prone to ascending aortic dilatation (AAD) involving both the tubular segment and the aortic root. The genetic factor was proposed as one of the most important mechanisms for...

    Authors: Mingjia Ma, Zongzhe Li, Mohamed Abdulkadir Mohamed, Ligang Liu and Xiang Wei
    Citation: BMC Cardiovascular Disorders 2021 21:413
  4. Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain.

    Authors: Ali Sheikhy, Aida Fallahzadeh, Saeed Sadeghian, Khalil Forouzannia, Jamshid Bagheri, Abbas Salehi-Omran, Masih Tajdini, Arash Jalali, Mina Pashang and Kaveh Hosseini
    Citation: BMC Cardiovascular Disorders 2021 21:412
  5. Self-reported health status as measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ) in patients with primary prevention implantable cardioverter defibrillators (ICDs) has mainly been reported from r...

    Authors: Gustav Mattsson, Marita Wallhagen and Peter Magnusson
    Citation: BMC Cardiovascular Disorders 2021 21:411
  6. Rates of recommending percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) vary across clinicians. Whether clinicians agree on preferred treatment options for multivessel coronar...

    Authors: Elizabeth L. Nichols, Glyn Elwyn, Anthony DiScipio, Mandeep S. Sidhu, A. James O’Malley, Daniel D. Matlock, Shama Alam, Cathy S. Ross, Megan Coylewright, David J. Malenka and Jeremiah R. Brown
    Citation: BMC Cardiovascular Disorders 2021 21:410
  7. The number of women with congenital heart disease (CHD) who are of childbearing age is increasing due to advancements in medical management. Nonetheless, data on the outcomes of delivery in women with CHD rema...

    Authors: Manabu Nitta, Sayuri Shimizu, Makoto Kaneko, Kiyohide Fushimi and Shinichiro Ueda
    Citation: BMC Cardiovascular Disorders 2021 21:409
  8. Type A aortic dissection is a very dangerous, fatal, and emergency condition for surgery. Acute aortic dissection is a rare condition, such that many patients will not survive without reconstructive surgery.

    Authors: Masoud Shafiee, Mohsen Shafiee, Noorollah Tahery, Omid Azadbakht, Zeinab Nassari and Reza Baghbani
    Citation: BMC Cardiovascular Disorders 2021 21:408
  9. Pulmonary vein isolation (PVI) is the cornerstone of the interventional treatment of atrial fibrillation (AF). Traditionally, during these procedures the catheters are guided by fluoroscopy, which poses a risk...

    Authors: Tamas Tahin, Adam Riba, Barnabas Nemeth, Ferenc Arvai, Geza Lupkovics, Gabor Szeplaki and Laszlo Geller
    Citation: BMC Cardiovascular Disorders 2021 21:407
  10. The impact of thrombocytopenia on infection in patients with ST-elevation myocardial infarction (STEMI) remains poorly understood.

    Authors: Litao Wang, Weijiang Su, Jinhua Xue, Xiao Gong, Yining Dai, Jiyan Chen, Ling Xue, Pengcheng He, Yuanhui Liu and Ning Tan
    Citation: BMC Cardiovascular Disorders 2021 21:404
  11. Cardiomyocyte metabolism changes before cardiac remodeling, but its role in early cardiac hypertrophy detection remains unclear. This study investigated early changes in plasma metabolomics in a pressure-overl...

    Authors: Jialing Liu, Junhao Hu, Lanlan Tan, Qi Zhou and Xiaojing Wu
    Citation: BMC Cardiovascular Disorders 2021 21:403
  12. In the treatment of coronary heart disease, target vessel revascularization (TVR) has attracted increasing attention as an efficient means of percutaneous coronary intervention (PCI). The purpose of this study...

    Authors: Tiancheng Xu, Beili Feng, Zaixing Zheng, Licheng Li, Weifang Zeng, Dongjuan Wang, Lin Zhang and Hengdong Li
    Citation: BMC Cardiovascular Disorders 2021 21:402
  13. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Changrong Nie, Changsheng Zhu, Qiulan Yang, Minghu Xiao, Yanhai Meng and Shuiyun Wang
    Citation: BMC Cardiovascular Disorders 2021 21:401

    The original article was published in BMC Cardiovascular Disorders 2021 21:382

  14. Elevated plasma carbohydrate antigen-125 (CA-125) levels are strongly associated with new-onset atrial fibrillation (AF) and heart failure, but the relationship between plasma CA-125 level and AF recurrence fo...

    Authors: Qingya Wang, Chengjing Dang, Haoyu Liu and Jie Hui
    Citation: BMC Cardiovascular Disorders 2021 21:400
  15. To evaluate the safety and efficacy of excimer laser coronary atherectomy (ELCA) in patients with in-stent restenosis chronic total occlusions (ISR CTOs).

    Authors: Hui Li, Hu Ai, Le Li, Naixin Zheng, Guodong Tang, Guojian Yang, Ying Zhao, Fucheng Sun and Huiping Zhang
    Citation: BMC Cardiovascular Disorders 2021 21:399
  16. Congenital heart disease (CHD) accounts for nearly a third of all major congenital anomalies. Advances in pediatric cardiology shifted attention from mortality to morbidity and health-related quality of life (...

    Authors: Teresa Grimaldi Capitello, Francesca Bevilacqua, Roberta Vallone, Anna Maria Dall’Oglio, Francesca Santato, Salvatore Giannico, Giulio Calcagni, Simone Piga, Marta Ciofi degli Atti, Simonetta Gentile and Angela Rossi
    Citation: BMC Cardiovascular Disorders 2021 21:398
  17. We sought to identify the electrocardiographic and electrophysiological characteristics of ventricular arrhythmias (VAs), including idiopathic ventricular tachycardia (VT) and premature ventricular contraction...

    Authors: Chengye Di, Konstantinos P. Letsas, Peng Gao, Qun Wang, Yanxi Wu and Wenhua Lin
    Citation: BMC Cardiovascular Disorders 2021 21:397
  18. Inflammation is one of the principal triggering mechanisms for left ventricular fibrosis and remodeling in heart failure, leading to adverse clinical outcomes. Soluble suppression of tumorigenicity 2 (sST2), a...

    Authors: Fuhai Li, Mengying Xu, Mingqiang Fu, Xiaotong Cui, Zhexun Lian, Hui Xin, Jingmin Zhou and Junbo Ge
    Citation: BMC Cardiovascular Disorders 2021 21:396
  19. Knowledge of stenosis in coronary arteries requires an understanding of the cellular and molecular processes that occur throughout the leukocyte rolling process. In this study, the roles of miR-125a-5p and miR...

    Authors: Adeleh Poursaleh, Farnaz Sadegh Beigee, Golnaz Esfandiari and Mohammad Najafi
    Citation: BMC Cardiovascular Disorders 2021 21:395
  20. The development of metabolic syndrome (MS) augments risk for atherosclerotic cardiovascular disease (CVD), but pathophysiological mechanisms of this relation are still under discussion. Overlapping CVD risk fa...

    Authors: Egidija Rinkūnienė, Vilma Dženkevičiūtė, Žaneta Petrulionienė, Eglė Majauskienė, Ligita Ryliškytė, Roma Puronaitė, Jolita Badarienė, Rokas Navickas and Aleksandras Laucevičius
    Citation: BMC Cardiovascular Disorders 2021 21:393
  21. To investigate the clinical features of patients with Stanford type A acute aortic dissection (AAD) and analyze the risk factors affecting postoperative in-hospital mortality rate.

    Authors: Chen Ke, Hao Wu, Min Xi, Wei Shi, Qihong Huang and Guirong Lu
    Citation: BMC Cardiovascular Disorders 2021 21:392
  22. Acute coronary syndrome (ACS) has become a vital disease with high mortality in the Uygur populations. Clopidogrel plays an important role in reducing the risk of recurrent cardiovascular events after ACS; how...

    Authors: Luhai Yu, Tingting Wang, Huidong Bai, Weijiang Zhu, Yanju Li, Jianhua Wu, Wenli Liu, Li Sun, Aiping Yu and Hongjian Li
    Citation: BMC Cardiovascular Disorders 2021 21:391
  23. Atrial fibrillation (AF) is a common arrhythmia in patients with hypertension. ELABELA, which has cardioprotective effects, is decreased in the plasma of patients with hypertension and might be associated with...

    Authors: Zheng Ma, Lei Zhao, Ye-ping Zhang, Jiu-chang Zhong and Xin-chun Yang
    Citation: BMC Cardiovascular Disorders 2021 21:390
  24. We report a rare case of left ventricular inflow obstruction from a branch of the left circumflex coronary artery to the right atrium caused by a coronary arteriovenous fistula (CAVF) in a young Japanese male ...

    Authors: Ayako Chida-Nagai, Hirokuni Yamazawa, Takao Tsujioka, Kota Taniguchi, Osamu Sasaki, Gaku Izumi, Nobuyasu Kato and Atsuhito Takeda
    Citation: BMC Cardiovascular Disorders 2021 21:389
  25. Catheter-based renal denervation (RDN) has been introduced to treat resistant hypertension. Although the technology of RDN has been largely improved, denervation of tortuous renal arteries remains challenging.

    Authors: Peijiang Wang, Jindong Wan, Jixin Hou, Sen Liu and Fei Ran
    Citation: BMC Cardiovascular Disorders 2021 21:388
  26. Transmural lesion creation is essential for effective atrial fibrillation (AF) ablation. Lesion characteristics between conventional energy and high-power short-duration (HPSD) setting in contact force-guided ...

    Authors: Chun-Chao Chen, Po-Tseng Lee, Vu Van Ba, Chieh-Mao Chuang, Yenn-Jiang Lin, Li-Wei Lo, Yu-Feng Hu, Fa-Po Chung, Chin-Yu Lin, Ting-Yung Chang, Jennifer Jeanne Vicera, Ting-Chun Huang, Chih-Min Liu, Cheng-I Wu, Isaiah C. Lugtu, Ankit Jain…
    Citation: BMC Cardiovascular Disorders 2021 21:387
  27. Comparative studies regarding the long-term clinical outcomes of statin intensity between acute myocardial infarction (AMI) patients with prediabetes and those with type 2 diabetes mellitus (T2DM), after succe...

    Authors: Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong and Yangsoo Jang
    Citation: BMC Cardiovascular Disorders 2021 21:386
  28. Essential hypertension is a complex disease determined by the interaction of genetic and environmental factors, eNOS is considered to be one of the susceptible genes for hypertension. Our study aimed to evaluate ...

    Authors: Jikang Shi, Siyu Liu, Yanbo Guo, Sainan Liu, Jiayi Xu, Lingfeng Pan, Yueyang Hu, Yawen Liu and Yi Cheng
    Citation: BMC Cardiovascular Disorders 2021 21:385
  29. This study assessed the sociodemographic, functional, and clinical determinants of antithrombotic treatment in patients with nonvalvular atrial fibrillation (NVAF) attended in the internal medicine setting.

    Authors: Jose María Mostaza, Carmen Suarez, Jose María Cepeda, Luis Manzano and Demetrio Sánchez
    Citation: BMC Cardiovascular Disorders 2021 21:384
  30. Patients with acute coronary syndromes often experience non-specific (generic) pain after hospital discharge. However, evidence about the association between post-discharge non-specific pain and rehospitalizat...

    Authors: Jinying Chen, Catarina I. Kiefe, Marc Gagnier, Darleen Lessard, David McManus, Bo Wang and Thomas K. Houston
    Citation: BMC Cardiovascular Disorders 2021 21:383
  31. Myocardial bridging (MB) is associated with various forms of arrhythmia. However, whether MB is a risk factor for atrial fibrillation (AF) in patients with hypertrophic obstructive cardiomyopathy (HOCM) remain...

    Authors: Changrong Nie, Changsheng Zhu, Qiulan Yang, Minghu Xiao, Yanhai Meng and Shuiyun Wang
    Citation: BMC Cardiovascular Disorders 2021 21:382

    The Correction to this article has been published in BMC Cardiovascular Disorders 2021 21:401

  32. It has been suggested that patent foramen ovale (PFO) contributes to the majority of cryptogenic stroke cases in young people, however, the direct link is still undetermined. Here we analyzed the correlation b...

    Authors: Gang Liu, Zhao Feng, Fan Feng, Changju Xue, Fei Liu and Xiaoting Xie
    Citation: BMC Cardiovascular Disorders 2021 21:381
  33. Anti-Ku is a rare antibody which can be positive in some rheumatic diseases and it might be related to cardiac involvement. Polymyositis is an inflammatory myopathy, and its cardiac involvement seldom presents...

    Authors: Weiping Tan, Bin Dong, Jincui Gu, Yang Peng and Ruicong Xue
    Citation: BMC Cardiovascular Disorders 2021 21:380
  34. Chronic heart failure (CHF) comorbid with atrial fibrillation (AF) is a serious threat to human health and has become a major clinical burden. This prospective cohort study was performed to design a risk strat...

    Authors: Chu Zheng, Jing Tian, Ke Wang, Linai Han, Hong Yang, Jia Ren, Chenhao Li, Qing Zhang, Qinghua Han and Yanbo Zhang
    Citation: BMC Cardiovascular Disorders 2021 21:379
  35. Toll-like receptor 4 (TLR4) and matrix metalloproteinase 9 (MMP9) have been investigated to play significant roles in the formation of abdominal aortic aneurysm (AAA). But the reports on the expression pattern...

    Authors: Tan Li, Xintong Li, Xiaozheng Liu, Jun Yang and Chunyan Ma
    Citation: BMC Cardiovascular Disorders 2021 21:378
  36. Patients with both double orifice mitral valve (DOMV) and bicuspid aortic valve (BAV) malformation are rare. Although DOMV or BAV can be detected in some genetic syndromes, it has not been reported to simultan...

    Authors: Feifei Sun, Xueying Tan, Aijiao Sun, Xintong Zhang, Yanxiao Liang and Weidong Ren
    Citation: BMC Cardiovascular Disorders 2021 21:377
  37. H type hypertension is defined as homocysteine (Hcy) ≥ 10 μmol/L in combination with primary hypertension. Studies demonstrated that the existence of hyperhomocysteine (HHcy) in hypertensive exacerbates the po...

    Authors: Xiao-lin Qian, Hong Cao, Jun Zhang, Zhi-hui Gu, Wei-qin Tang, Lei Shen, Jia-lu Hu, Zhi-feng Yao, Lei Zhang, Min-na Tang, Xu-cheng Lv, Jun Zhou, Xue-juan Jin, Bin Hong, Zhao-qiang Cui and Jun-bo Ge
    Citation: BMC Cardiovascular Disorders 2021 21:376
  38. Half of U.S. adults have received at least one dose of the COVID-19 vaccines produced by either Pfizer, Moderna, or Johnson and Johnson, which represents a major milestone in the ongoing pandemic. Given the em...

    Authors: Ammar A. Hasnie, Usman A. Hasnie, Nirav Patel, Muhammad U. Aziz, Min Xie, Steven G. Lloyd and Sumanth D. Prabhu
    Citation: BMC Cardiovascular Disorders 2021 21:375
  39. As the burden of cardiovascular disease increases in sub-Saharan Africa, there is a growing need for low-cost interventions to mitigate its impact. Providing self-care health education to patients with chronic...

    Authors: Getenet Dessie, Sahai Burrowes, Henok Mulugeta, Dessalegn Haile, Ayenew Negess, Dubie Jara, Girma Alem, Bekele Tesfaye, Haymanot Zeleke, Tenaw Gualu, Temsgen Getaneh, Getiye Dejenu Kibret, Desalegne Amare, Endalkachew Worku Mengesha, Fasil Wagnew and Rasheda Khanam
    Citation: BMC Cardiovascular Disorders 2021 21:374
  40. The aim of the present study is to evaluate the short-term efficacy and feasibility of radiofrequency ablation in the treatment of complex diffuse arteriovenous (AV) malformations.

    Authors: Chun-Xiao Ge, Mao-Zhong Tai, Tao Chen, Ke-Lei Li, Zhen-Guo Xu and Zhong-Ping Qin
    Citation: BMC Cardiovascular Disorders 2021 21:373
  41. Complete atrioventricular block (AVB) is a life-threatening condition that usually occurs in elderly people with organic heart disease. We herein describe a rare case of complete AVB in a young man with hypert...

    Authors: Shu Fang, Lan Gao, Fan Yang and Yan-jun Gong
    Citation: BMC Cardiovascular Disorders 2021 21:372
  42. Among changes in demographics, aging is the most relevant cardiovascular risk factor. The prevalence of peripheral artery disease (PAD) is high in elderly patients and is associated with a worse prognosis. Des...

    Authors: Christos Rammos, Aristotelis Kontogiannis, Amir A. Mahabadi, Martin Steinmetz, Daniel Messiha, Julia Lortz and Tienush Rassaf
    Citation: BMC Cardiovascular Disorders 2021 21:370
  43. Age-associated inflammation and immune system dysfunction have been implicated as mechanisms that increase risk for adverse long-term procedural outcomes in older adults. The purpose of this study was to inves...

    Authors: Deena S. Goldwater, Mei Leng, Arun Karlamangla, Teresa Seeman, David Elashoff, Jonathan M. Wanagat, David B. Reuben, Brian R. Lindman and Steve Cole
    Citation: BMC Cardiovascular Disorders 2021 21:368
  44. In the treatment of coronary heart disease, secondary prevention goals are still often unmet and poor adherence to prescribed drugs has been suggested as one of the reasons. We aimed to investigate whether pha...

    Authors: Malin Johansson Östbring, Tommy Eriksson, Göran Petersson and Lina Hellström
    Citation: BMC Cardiovascular Disorders 2021 21:367
  45. An electrocardiogram (ECG) is a mandatory test for anyone presenting with loss of consciousness. Many referrals to the first seizure clinic (FSC) are caused by syncope. We assessed the sensitivity of neurologi...

    Authors: Xuya Huang, N. Malek, J. Simpson, D. Kalladka, F. G. Dunn and J. P. Leach
    Citation: BMC Cardiovascular Disorders 2021 21:364

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