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  1. Sub-Saharan Africa (SSA) is experiencing an increasing burden of Cardiovascular Diseases (CVDs). Modifiable risk factors including hypertension, diabetes, obesity, central obesity, sedentary behaviours, smokin...

    Authors: Geofrey Musinguzi, Rawlance Ndejjo, Isaac Ssinabulya, Hilde Bastiaens, Harm van Marwijk and Rhoda K. Wanyenze
    Citation: BMC Cardiovascular Disorders 2020 20:284
  2. Evidence on association between body composition and outcomes of transcatheter aortic valve implantation (TAVI) is limited for Asian patients. This study investigated the prognostic role of body composition pa...

    Authors: Hsiao-Huang Chang, Po-Lin Chen, Hsin-Bang Leu, I-Ming Chen, Nai-Yuan Wu and Ying-Hwa Chen
    Citation: BMC Cardiovascular Disorders 2020 20:283
  3. While the benefit of adherence to statins on clinical outcomes has been proved, this benefit may be heterogeneous among patients who initiated statins for primary or secondary prevention purpose. This study ai...

    Authors: Boya Zhao, Xiaoning He, Jing Wu and Shu Yan
    Citation: BMC Cardiovascular Disorders 2020 20:282
  4. Thromboembolic ischemic stroke (IS) is one of the most feared complications of left ventricular assist device (LVAD) placement and represents a challenge to surgical management because of concomitant anticoagu...

    Authors: Walid Oulehri, Mircea Cristinar, Gharib Ajob, Sandrine Marguerite, Bob Heger, Hélène Cebula, Michel Kindo and Paul Michel Mertes
    Citation: BMC Cardiovascular Disorders 2020 20:281
  5. Data was limited on the rates of in-hospital and 30-days composite outcomes between male and female patients with coronary heart disease (CHD) undergoing percutaneous coronary intervention (PCI).

    Authors: Juan Long, Fanfang Zeng, Lili Wang, Chen Yi, Qiying Chen and Honglei Zhao
    Citation: BMC Cardiovascular Disorders 2020 20:280
  6. The association of rs28362491 polymorphism in NF-κB1 gene and coronary artery disease (CAD) risk was reported in several studies with inconsistent outcomes. This study aimed to comprehensively collect and synthes...

    Authors: Yanwei Wang, Bianwen Wu, Muqing Zhang, Huawei Miao and Jiaan Sun
    Citation: BMC Cardiovascular Disorders 2020 20:278
  7. Most electrocardiogram (ECG) studies still take advantage of traditional statistical functions, and the results are mostly presented in tables, histograms, and curves. Few papers display ECG data by visual mea...

    Authors: Haisen Guo, Weidai Zhang, Chumin Ni, Zhixiong Cai, Songming Chen and Xiansheng Huang
    Citation: BMC Cardiovascular Disorders 2020 20:277
  8. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Daniel Paul Fudulu, Gianni Davide Angelini, Fani Fanoula Papadopoulou, Jonathan Evans, Terrie Walker-Smith, Ido Kema, Martijn Van Faassen, Serban Stoica, Massimo Caputo, Stafford Lightman and Benjamin Gibbison
    Citation: BMC Cardiovascular Disorders 2020 20:276

    The original article was published in BMC Cardiovascular Disorders 2020 20:245

  9. Adverse cardiac remodeling with a myocardial fibrosis as a key pathophysiologic component may be associated to worse survival in aortic stenosis (AS) patients. Therefore, with the application of advanced cardi...

    Authors: Giedrė Balčiūnaitė, Darius Palionis, Edvardas Žurauskas, Viktor Skorniakov, Vilius Janušauskas, Aleksejus Zorinas, Tomas Zaremba, Nomeda Valevičienė, Audrius Aidietis, Pranas Šerpytis, Kęstutis Ručinskas, Peter Sogaard and Sigita Glaveckaitė
    Citation: BMC Cardiovascular Disorders 2020 20:275
  10. Ventricular strain measurements vary depending on cardiac chamber (left ventricle [LV] or right ventricle [RV]), type of strain (longitudinal, circumferential, or radial), ventricular level (basal, mid, or api...

    Authors: Hongmei Xia, Darwin F. Yeung, Cristina Di Stefano, Stephen S. Cha, Patricia A. Pellikka, Zi Ye, Jeremy J. Thaden and Hector R. Villarraga
    Citation: BMC Cardiovascular Disorders 2020 20:274
  11. Trimetazidine is a metabolic anti-ischemic agent, which increases the tolerance of cardiomyocytes to ischemia. However, few studies have explored the effect of trimetazidine on ventricular remodeling in corona...

    Authors: Lili Wu, Yi Luan, Ya Li, Min Wang, Jialin He, Chongying Jin and Wenbin Zhang
    Citation: BMC Cardiovascular Disorders 2020 20:273
  12. Participation in an assessment may change health behavior. This “mere-measurement effect” may be used for prevention purposes. However, little is known about whether individuals’ characteristics moderate the e...

    Authors: Lisa Voigt, Antje Ullrich, Sophie Baumann, Marcus Dörr, Ulrich John and Sabina Ulbricht
    Citation: BMC Cardiovascular Disorders 2020 20:272
  13. Visfatin is an adipokine that related with the inflammation in atherosclerosis and the destabilization of atherosclerotic plaque. The aim of this study was to observe the relationship between visfatin and majo...

    Authors: Meifan Zheng, Nan Lu, Meixia Ren and Haifeng Chen
    Citation: BMC Cardiovascular Disorders 2020 20:271
  14. Underweight or obese status influences the prognosis of atrial fibrillation (AF). However, the association between stratification of body mass index (BMI) and in-hospital outcomes in patients with AF, remains ...

    Authors: Fuxue Deng, Yan Zhang, Qiang Zhao, Yangyang Deng, Shanshan Gao, Lisha Zhang, Mengya Dong, Zuyi Yuan and Xinjun Lei
    Citation: BMC Cardiovascular Disorders 2020 20:270
  15. Peripartum cardiomyopathy (PPCM) is life-threatening heart disease. However, the causes and pathogenesis of PPCM remain unclear. Previous studies found that β1 adrenoceptor antibodies (β1AA) had possible invol...

    Authors: Linying Shi, Jia Liu, Yuan Zhang, Mulei Chen and Jiamei Liu
    Citation: BMC Cardiovascular Disorders 2020 20:269
  16. To mitigate the risk of stent thrombosis, patients treated by percutaneous coronary intervention (PCI) are administered dual anti-platelet therapy comprising aspirin and a platelet P2Y12 receptor inhibitor. Clopi...

    Authors: Abdullah M. Al-Rubaish, Fahad A. Al-Muhanna, Abdullah M. Alshehri, Mohammed A. Al-Mansori, Rudaynah A. Alali, Rania M. Khalil, Khalid A. Al Faraidy, Cyril Cyrus, Mohammed M. Sulieman, Chittibabu Vatte, Daniel M. F. Claassens, Jurriën M. ten Berg, Folkert W. Asselbergs and Amein K. Al-Ali
    Citation: BMC Cardiovascular Disorders 2020 20:268
  17. Parameters that mark the timing of left ventricular (LV) reverse remodeling following transcatheter aortic valve replacement (TAVR) are incompletely defined. This study aims to identify the dynamics of LV stra...

    Authors: Fadi Al-Rashid, Matthias Totzeck, Nadine Saur, Rolf Alexander Jánosi, Alexander Lind, Amir A. Mahabadi, Tienush Rassaf and Raluca-Ileana Mincu
    Citation: BMC Cardiovascular Disorders 2020 20:267
  18. Preventive intra-aortic balloon pump (IABP) for high-risk patients with stable hemodynamics is controversial, and its definition of high-risk is still unclear. This study aimed to investigate the effect of pro...

    Authors: Ju-Bing Zheng, Kun Hua, Kui Zhang, Shao-You Zhou, Shi-Jun Xu, Juan-Juan Sheng and Ran Dong
    Citation: BMC Cardiovascular Disorders 2020 20:266
  19. To evaluate the association between apolipoprotein B gene polymorphism and coronary heart disease in some populations at home and abroad by means of meta-analysis.

    Authors: Ya Yun Feng, Lu Yang Chen, Yang Liu, Meng Luo, Tian Tian Yang, Yu Hao Hu, Jing Chang and Min Mao
    Citation: BMC Cardiovascular Disorders 2020 20:265
  20. Cardiovascular disease is second only to cancer recurrence as a determinant of lifespan in cancer survivors, and cancer therapy-related cardiac dysfunction is a clinically important risk factor. We aim to inve...

    Authors: Yoo Jin Hong, Gun Min Kim, Kyunghwa Han, Pan Ki Kim, Su An Lee, Eunkyung An, Ji Yeon Lee, Hye-Jeong Lee, Jin Hur, Young Jin Kim, Min Jung Kim and Byoung Wook Choi
    Citation: BMC Cardiovascular Disorders 2020 20:264
  21. The benefit of combining aspirin and direct oral anticoagulants on the reduction of cardiovascular events in atrial fibrillation or flutter is not well studied. We aimed to assess whether concurrent aspirin an...

    Authors: Ahmad Said, Scott Keeney, Marsel Matka, Adam Hafeez, Julie George and Alexandra Halalau
    Citation: BMC Cardiovascular Disorders 2020 20:263
  22. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a potential biomarker for monitoring the status of heart failure. However, the optimal monitoring interval of NT-proBNP is unknown. This study sought to...

    Authors: Zhehao Dai, Taku Asano, Osamu Takahashi, Nobuyuki Komiyama and Sachiko Ohde
    Citation: BMC Cardiovascular Disorders 2020 20:262
  23. One out of seven patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) may be affected by transthyretin cardiac amyloidosis (ATTR-CA), mostly presenting with low-fl...

    Authors: Guglielmo Gallone, Federico Landra, Fabrizio D’Ascenzo, Federico Conrotto, Roberta Casoni, Francesco Bruno, Pierluigi Omedè, Gianluca Alunni, Alessandro Andreis, Alessandro Vairo, Mauro Giorgi, Antonella Fava and Gaetano Maria De Ferrari
    Citation: BMC Cardiovascular Disorders 2020 20:261
  24. Isolated coronary Takayasu arteritis is a rare form of ischemic heart disease that typically appears as an aorto-ostial lesion. Although several vascular imaging modalities including ultrasonography, computed ...

    Authors: Takeshi Shimizu, Akihiko Sato, Keiji Sakamoto, Yoshitane Seino, Mikihiro Kijima, Toshiharu Matsumoto and Yasuchika Takeishi
    Citation: BMC Cardiovascular Disorders 2020 20:260
  25. Right ventricular (RV) function is a major determinant of outcome in patients with pulmonary hypertension. Cardiac magnetic resonance (CMR) is gold standard to assess RV ejection fraction (RVEFCMR), however this ...

    Authors: Anna Werther Evaldsson, Anthony Lindholm, Raluca Jumatate, Annika Ingvarsson, Gustav Jan Smith, Johan Waktare, Göran Rådegran, Anders Roijer, Carl Meurling and Ellen Ostenfeld
    Citation: BMC Cardiovascular Disorders 2020 20:259
  26. BMI has been implicated as a risk factor for heart disease as a whole in multiple studies. Heart attack is one of the common complications of this disease. The aim of this study is to explore if elevated level...

    Authors: Benjamin Adams, Lauren Jacocks and Hui Guo
    Citation: BMC Cardiovascular Disorders 2020 20:258
  27. Reported effects of obesity on the extent of angiographic coronary artery disease(CAD) have been inconsistent. The present study aimed to investigate the relationships between the indices of obesity and other ...

    Authors: Maryam Nabati, Mahmood Moosazadeh, Ehsan Soroosh, Hanieh Shiraj, Mahnaneh Gholami and Ali Ghaemian
    Citation: BMC Cardiovascular Disorders 2020 20:257
  28. Spontaneous isolated superior mesenteric artery dissection (SISMAD) is a rare vascular disorder, and the treatment strategies remain controversial. This study aimed to compare outcomes of conservative and endo...

    Authors: Leyin Xu, Jiang Shao, Daming Zhang, Chenyang Qiu, Jingjing Wang, Kang Li, Lijing Fang, Xin Zhang, Jinsong Lei, Zhichao Lai, Jiangyu Ma, Yanying Yu, Xiaoxi Yu, Fenghe Du, Wanting Qi, Junye Chen…
    Citation: BMC Cardiovascular Disorders 2020 20:256
  29. Most of the studies of obesity and postoperative outcome have looked predominantly at coronary artery bypass grafting with fewer focused on valvular disease. The purpose of this study was to compare the outcom...

    Authors: Keir Forgie, Sabin J. Bozso, Yongzhe Hong, Colleen M. Norris, Abdullah Ishaque, Richdeep S. Gill, Darren H. Freed, Michael C. Moon, Jayan Nagendran and Jeevan Nagendran
    Citation: BMC Cardiovascular Disorders 2020 20:255
  30. The growing population of cancer survivors and their high frequency of cardiovascular disease have resulted in a dramatic increase in cancer patients requiring cardiovascular intervention. However, there is a ...

    Authors: Alexandra C. Murphy, Anoop N. Koshy and Matias B. Yudi
    Citation: BMC Cardiovascular Disorders 2020 20:254
  31. Peripherally inserted central catheters (PICCs) are widely used in cancer patients for administering chemotherapy drugs, antibiotics, and nutrients. PICC-related thrombi are not uncommon and may result in pulm...

    Authors: Yu Lan Luo, Jinmei Zhang and Menglin Tang
    Citation: BMC Cardiovascular Disorders 2020 20:252
  32. Heart failure is one of leading cause of death worldwide. However, the transcriptional profiling of heart failure is unclear. Moreover, the signaling pathways and transcription factors involving the heart fail...

    Authors: Haiwei Wang, Xinrui Wang, Liangpu Xu and Hua Cao
    Citation: BMC Cardiovascular Disorders 2020 20:250
  33. Coronary slow flow (CSF) is characterized by delayed opacification of distal epicardial coronary arteries without significant coronary stenosis. In addition, The changes of lipoprotein-associated phospholipase...

    Authors: Yao-dong Ding, Yu-qiang Pei, Rui Wang, Jia-xing Yang, Yin-xin Zhao, Xiao-li Liu, Hua Shen, Qian Ma, Shuo Zhang and Hai-long Ge
    Citation: BMC Cardiovascular Disorders 2020 20:248
  34. Cortisol is the main stress hormone mobilised during surgery to establish homeostasis. Our current understanding of the hypothalamic-pituitary-adrenal axis physiology in children undergoing cardiopulmonary byp...

    Authors: Daniel Paul Fudulu, Gianni Davide Angelini, Fani Fanoula Papadopoulou, Jonathan Evans, Terrie Walker-Smith, Ido Kema, Martijn van Faassen, Serban Stoica, Massimo Caputo, Stafford Lightman and Benjamin Gibbison
    Citation: BMC Cardiovascular Disorders 2020 20:245

    The Correction to this article has been published in BMC Cardiovascular Disorders 2020 20:276

  35. Although timely coronary intervention can result in markedly improved clinical outcomes of patients with acute coronary syndrome (ACS), non-ST-elevation (NSTE)-ACS is sometimes difficult to accurately diagnose.

    Authors: Tetsuya Nomura, Satoshi Tasaka, Kenshi Ono, Yu Sakaue, Naotoshi Wada, Natsuya Keira and Tetsuya Tatsumi
    Citation: BMC Cardiovascular Disorders 2020 20:244
  36. Ischemic heart disease (IHD) is the leading cause of premature death which poses public health challenges worldwide. Previous studies focused on the overall population in China. However, variations in temporal...

    Authors: Chenran Wang, Chunping Wang, Mi Liu, Zhe Chen and Shiwei Liu
    Citation: BMC Cardiovascular Disorders 2020 20:243
  37. Cardiac fibroblasts, regarded as the immunomodulatory hub of the heart, have been thought to play an important role during sepsis-induced cardiomyopathy (SIC). However, the detailed molecular mechanism and tar...

    Authors: Jingjing Ji, Zhifeng Liu, Xinxin Hong, Zheying Liu, Jinghua Gao and Jinghua Liu
    Citation: BMC Cardiovascular Disorders 2020 20:242
  38. Mean platelet volume (MPV) has been identified as an individual risk factor for stroke and thrombosis. Concurrently, ischaemic stroke caused by nonvalvular atrial fibrillation (AF) has attracted increasing att...

    Authors: Meifang Zheng, Shean Chen, Ye Zhu and Xiang Gu
    Citation: BMC Cardiovascular Disorders 2020 20:241
  39. This study aimed to investigate the regulatory effect of rno-microRNA-30c-5p (rno-miR-30c-5p) on myocardial ischemia reperfusion (IR) injury in rats and the underlying molecular mechanisms.

    Authors: Jianfeng Chen, Mingming Zhang, Shouyan Zhang, Junlong Wu and Shufeng Xue
    Citation: BMC Cardiovascular Disorders 2020 20:240
  40. Prevalence of coronary heart disease (CHD) risk factors are increasing in developing countries. The present study aimed to assess the prevalence of self-reported CHD and evaluate the role of various risk facto...

    Authors: Ali Ghaemian, Maryam Nabati, Majid Saeedi, Motahareh Kheradmand and Mahmood Moosazadeh
    Citation: BMC Cardiovascular Disorders 2020 20:238
  41. The current analysis was performed to estimate the percentage and number of Chinese adults with hypertension and the percentage and number of Chinese adults recommended to receive pharmacological antihypertens...

    Authors: Yundi Jiao, Zhaoqing Sun, Yanxia Xie, Jia Zheng, Zhao Li, Xiaofan Guo, Yue Dai, Liqiang Zheng and Yingxian Sun
    Citation: BMC Cardiovascular Disorders 2020 20:237
  42. Atrial fibrillation (AF) is the most common supra ventricular cardiac arrhythmia, which presents with variety of clinical symptoms. Hypertension increases risk of developing Atrial fibrillation by 1.5 fold. To...

    Authors: Smita Bhalia, Pedro Pallangyo, Abuu Dalidali, Saada Salum, Richard Kawajika, Edna Kajuna, Happiness Kusiima, Engerasiya Kifai, Peter Kisenge, Tatizo Waane and Mohamed Janabi
    Citation: BMC Cardiovascular Disorders 2020 20:235
  43. May-Thurner syndrome (MTS) or Cockett’s syndrome is a rare clinical syndrome, which refers to the compression of the left common iliac vein (LCIV) by right common iliac artery and vertebral body. Complications...

    Authors: Yan Meng, Hao Qin, Qiang Ma, Junbo Zhang, Bo Zhang, Honggang Pang, Qian Yin and Hongyan Tian
    Citation: BMC Cardiovascular Disorders 2020 20:233

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