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Table 1 Baseline Characteristics

From: Coronary calcium density in relation to coronary heart disease and cardiovascular disease in adults with diabetes or metabolic syndrome: the Multi-ethnic Study of Atherosclerosis (MESA)

 

DM

(n = 668)

MetS

(n = 1122)

Neither DM/MetS

(n = 2028)

p value

Age, years

66.4 ± 9.0

65.7 ± 9.5

66.0 ± 9.7

0.14

Male

389 (58.2%)

543 (48.4%)

1217 (60.0%)

< 0.01

Race/ethnicity

Caucasian

157 (23.5%)

499 (44.5%)

991 (48.9%)

< 0.01

African American

239 (35.8%)

251 (22.4%)

467 (23.0%)

< 0.01

Chinese

81 (12.1%)

108 (9.6%)

251 (12.4%)

0.06

Hispanic

191 (28.6%)

264 (23.5%)

319 (15.7%)

< 0.01

Current smokers

81 (12.1%)

135 (12.0%)

267 (13.2%)

0.59

BMI, kg/m2

30.5 ± 6.0

30.7 ± 5.0

26.6 ± 4.6%

< 0.01

SBP, mmHg

134.0 ± 22.8

134.8 ± 20.9

126.2 ± 21.0

< 0.01

Cholesterol, mmol/L [mg/dL]

4.9 ± 1.1

[188.8 ± 40.7]

5.1 ± 1.0

[195.6 ± 38.1]

5.1 ± 0.9

[195.4 ± 34.6]

0.0001

HDL-C, mmol/L [mg/dL]

1.2 ± 0.3

[45.9 ± 13.1]

1.1 ± 0.3

[42.8 ± 10.5]

1.4 ± 0.4

[54.6 ± 14.8]

< 0.01

10-year ASCVD score, %

30.5 ± 18.0

17.0 ± 12.2

15.0 ± 11.9

< 0.01

Hypertension treatment

435 (65.1%)

645 (57.5%)

678 (33.4%)

< 0.01

Statin treatment

217 (32.5%)

254 (22.6%)

376 (18.5%)

< 0.01

CAC Agatston score

345.9 ± 645.3

241.1 ± 494.4

237.4 ± 485.4

< 0.01

CAC volume score, mm3

307.8 ± 545.2

213.9 ± 410.4

208.5 ± 402.1

< 0.01

CAC density

2.59 ± 0.76

2.53 ± 0.75

2.60 ± 0.76

0.03

  1. Continuous variables were presented as means (SD) and categorical variables as frequency (percentage)
  2. ASCVD  atherosclerotic cardiovascular disease, BMI  Body mass index, CAC  Coronary artery calcium, DM  Diabetes mellitus, HDL-C  High density lipoprotein-cholesterol, MetS = metabolic syndrome, SBP  Systolic blood pressure