Fig. 6

Effect of GDF-15 deficiency on the morphology (cell number, proliferation) of atherosclerotic plaques in the pulmonary trunk (PT). Immunohistomorphometric / histochemical analyses of atherosclerotic lesions in the PT of ApoE^−/− and GDF15^−/−ApoE^−/− mice after 20 weeks of CED. A Cell density and B Ki67 (proliferation). C representative Ki67⁺ immuno-stained cross sections; data are expressed as mean + SEM; scale bar: 100 µm; n = 4–5