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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: Technical advance in silico and in vitro development of a new bipolar radiofrequency ablation device for renal denervation

Fig. 4

A Computer simulation of the isothermal ablation zone for a 500 kHz input signal with an amplitude of 60 Vp-p at 60 s of ablation. The computer model predicted an ablation zone of 4 mm × 10 mm × 4 mm (length × width × height) over the bipolar electrodes. B Thermochromic tissue phantom (TCP) after an ablation signal (500 kHz, 60 Vp-p) was applied for 60 s. The dark pink color change corresponds to the area where the temperature exceeded 60 °C. Note the similarities with the computer model in A. C Ablation zone comparison between computer model (A) and TCP tissue experiment (B). The ablation zone was 3 mm × 8.5 mm × 3.5 mm. Note the very close correlation between the experimental and simulated ablation volumes. D ImageJ processing of C illustrating the thresholding and measurement of the ablated zone

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