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Table 1 Baseline clinical characteristics

From: Serum free fatty acids are associated with severe coronary artery calcification, especially in diabetes: a retrospective study

Variable

Total (n = 426)

Non-SCAC (n = 320)

SCAC (n = 106)

P value

Age, years

67.14 ± 10.29

65.62 ± 10.11

71.74 ± 9.44

 < 0.001

Male sex, %

281 (66.0)

213 (66.6)

68 (64.2)

0.650

BMI, kg/m2

24.40 ± 2.84

24.44 ± 2.80

24.29 ± 2.98

0.653

Smoking, %

221 (51.9)

170 (53.1)

51 (48.1)

0.371

Family history, %

103 (24.2)

75 (23.4)

28 (26.4)

0.535

Hypertension, %

303 (71.1)

221 (69.1)

82 (77.4)

0.102

Diabetes, %

124 (29.1)

84 (26.2)

40 (37.7)

0.024

Prior MI, %

42 (9.9)

30 (9.4)

12 (11.3)

0.560

Prior PCI %

90 (21.1)

62 (19.4)

28 (26.4)

0.124

Clinical presentation

   

0.980

SCAD

354 (83.1)

266 (83.1)

88 (83.0)

 

ACS

72 (16.9)

54 (16.9)

18 (17.0)

 

eGFR, ml/min/1.73m2

80.89 ± 20.79

82.51 ± 20.64

76.00 ± 20.56

0.005

HbA1c, %

6.34 ± 1.38

6.26 ± 1.33

6.59 ± 1.48

0.031

TG, mmol/L

1.63 ± 0.89

1.66 ± 0.87

1.54 ± 0.94

0.204

TC, mmol/L

4.17 ± 1.01

4.14 ± 0.97

4.24 ± 1.14

0.381

HDL, mmol /L

1.06 ± 0.26

1.05 ± 0.26

1.07 ± 0.28

0.465

LDL, mmol/L

2.66 ± 0.85

2.63 ± 0.82

2.74 ± 0.94

0.230

Serum FFAs, mmol/dl

5.51 ± 1.96

5.13 ± 1.73

6.62 ± 2.17

 < 0.001

SBP, mmHg

131.50 ± 17.02

130.03 ± 16.03

135.93 ± 19.10

0.002

DBP, mmHg

75.01 ± 10.52

75.48 ± 10.38

73.62 ± 10.89

0.116

PP, mmHg

56.51 ± 13.63

54.55 ± 12.55

62.41 ± 15.07

 < 0.001

Prior medical treatment

    

Anti-platelet drugs (n/%)

119 (28.0)

84 (26.3)

35 (33.0)

0.184

Statins (n/%)

99 (23.2)

73 (22.8)

26 (24.5)

0.717

ACEI/ARB (n/%)

194 (45.5)

139 (43.4)

55 (51.9)

0.130

β-blockers (n/%)

81 (19.0)

55 (17.2)

26 (24.5)

0.095

CCB (n/%)

144 (33.8)

102 (31.9)

42 (39.6)

0.144

Insulin (n/%)

32 (7.5)

21 (6.6)

11 (10.4)

0.197

  1. Data are expressed as the mean ± SD. BMI, body mass index; MI, myocardial infarction; PCI, percutaneous coronary intervention; SCAD, stable coronary artery disease; ACS, acute coronary syndrome; eGFR, estimated glomerular filtration rate; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; ACEI/ARB, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers; CCB, calcium channel blockers