Table 3 Baseline characteristics of the included patients according to the GS tertiles
1st tertile ≤ 45 (n = 250) | 2nd tertile 49–85 (n = 246) | 3rd tertile ≥ 85 (n = 241) | t/Z/χ2 | P | |
|---|---|---|---|---|---|
Sex (male/female) | 171/79 | 191/55 | 200/41 | 14.814 | 0.001 |
Age (years) | 55.37 ± 12.26 | 58.23 ± 11.84a | 60.53 ± 12.34ab | 11.111 | < 0.001 |
Hypertension | 106 (42.4) | 111 (45.1) | 114 (47.3) | 1.199 | 0.549 |
Diabetes mellitus | 45 (18.0) | 66 (26.8) | 82 (34.0)ab | 16.381 | < 0.001 |
Diabetes mellitus treatment | 0.846 | 0.932 | |||
Diet only | 2 (4.2) | 3 (6.7) | 3 (4.7) | ||
Oral hypoglycemic drugs | 23 (47.9) | 19 (42.2) | 32 (50.0) | ||
Insulin | 23 (47.9) | 23 (51.1) | 29 (45.3) | ||
Smoking | 9.963 | 0.041 | |||
Never smoker | 134 (53.6) | 119 (48.4) | 104 (43.2) | ||
Former smoker | 16 (6.4) | 13 (5.3) | 8 (3.3) | ||
Current smoker | 100 (40.0) | 114 (46.3) | 129 (53.5) | ||
Alcohol drinking | 1.053 | 0.902 | |||
Never drinking | 147 (58.8) | 153 (63.2) | 146 (60.6) | ||
Former drinking | 41 (16.4) | 36 (14.9) | 39 (16.2) | ||
Current drinking | 62 (24.8) | 53 (21.9) | 56 (23.2) | ||
Family history of CAD | 95 (38.0) | 100 (40.7) | 102 (42.3) | 0.972 | 0.615 |
SBP (mmHg) | 123.72 ± 20.64 | 122.37 ± 18.87 | 121 ± 19.85 | 1.157 | 0.315 |
DBP (mmHg) | 76.86 ± 13.88 | 77.45 ± 13.12 | 75.62 ± 13.3 | 1.174 | 0.310 |
Heart rate | 80.42 ± 14.05 | 81.78 ± 14.26 | 83.68 ± 16.58 | 2.930 | 0.054 |
BMI (kg/m2) | 24.78 ± 5.95 | 24.9 ± 5.05 | 25.11 ± 5.36 | 0.203 | 0.817 |
HDL-C (mmol/l) | 0.96 ± 0.23 | 0.99 ± 0.26 | 1.01 ± 0.28 | 2.152 | 0.117 |
LDL-C (mmol/l) | 2.88 ± 0.85 | 2.94 ± 0.74 | 3.04 ± 1 | 1.434 | 0.239 |
TC (mmol/l) | 4.63 ± 1.23 | 4.57 ± 0.98 | 4.68 ± 1.34 | 0.374 | 0.688 |
TG (mmol/l) | 2.14 ± 2.15 | 2.15 ± 2.13 | 1.98 ± 1.45 | 0.426 | 0.653 |
ApoA1 (g/L) | 1.2 ± 0.26 | 1.23 ± 0.3 | 1.29 ± 0.53 | 2.710 | 0.067 |
ApoB (g/L) | 0.9 ± 0.27 | 0.88 ± 0.23 | 0.96 ± 0.52 | 2.433 | 0.089 |
Lp(a) (g/L) | 234.48 ± 232.84 | 263.47 ± 280.29 | 222 ± 172.39 | 1.505 | 0.223 |
Cr (mmol/L) | 80.9 ± 35.25 | 80.52 ± 42.9 | 78.84 ± 52.29 | 0.150 | 0.860 |
BUN (mmol/l) | 5.71 ± 2.91 | 5.59 ± 2.87 | 5.5 ± 1.95 | 0.394 | 0.674 |
Uric acid (μmol/L) | 326.22 ± 92.64 | 335.89 ± 94.27 | 324.19 ± 92.59 | 1.090 | 0.337 |
WBC | 10.88 ± 3.74 | 10.87 ± 3.71 | 10.64 ± 3.29 | 0.339 | 0.712 |
Neutrophil count | 8.13 ± 3.63 | 8.37 ± 3.58 | 8.11 ± 3.15 | 0.419 | 0.658 |
lymphocyte count | 1.95 ± 1.27 | 1.76 ± 0.96 | 1.81 ± 1.07 | 1.954 | 0.142 |
NLR | 5.24 ± 3.90 | 6.41 ± 5.24 | 7.46 ± 5.51 | 12.506 | < 0.001 |
NLR tertiles | 19.287 | 0.001 | |||
1st tertile | 104 (41.6) | 77 (31.3) | 64 (26.6) | ||
2nd tertile | 84 (33.6) | 84 (34.1) | 77 (32.0) | ||
3rd tertile | 62 (24.8) | 85 (34.6) | 100 (41.5) | ||
Monocyte count | 0.59 ± 0.32 | 0.58 ± 0.32 | 0.57 ± 0.31 | 0.258 | 0.773 |
PLR | 158.09 ± 122.37 | 176.51 ± 159.31 | 166.74 ± 142.57 | 1.042 | 0.353 |
RBC | 4.75 ± 0.70 | 4.74 ± 0.73 | 4.79 ± 0.72 | 0.399 | 0.672 |
HGB | 145.15 ± 24.97 | 142.77 ± 27.85 | 144.62 ± 24.6 | 0.579 | 0.561 |
PLT | 223.74 ± 69.67 | 242.01 ± 203.23 | 224.52 ± 77.66 | 1.508 | 0.222 |
MPV | 10.20 ± 1.29 | 10.16 ± 1.75 | 10.2 ± 1.28 | 0.065 | 0.937 |
PDW | 13.66 ± 3.35 | 13.44 ± 3.78 | 12.98 ± 3.63 | 2.298 | 0.101 |
PCT | 0.24 ± 0.08 | 0.24 ± 0.11 | 0.24 ± 0.10 | 0.239 | 0.788 |
Clinical diagnosis | 1.672 | 0.796 | |||
UA | 38 (15.2) | 32 (13.0) | 30 (12.4) | ||
NSTEMI | 32 (12.8) | 26 (10.6) | 29 (12.0) | ||
STEMI | 180 (72.0) | 188 (76.4) | 182 (75.5) | ||
Aspirin | 18 (7.2) | 23 (9.3) | 33 (13.7) | 5.923 | 0.052 |
Statins | 17 (6.8) | 19 (7.7) | 31 (12.9)ab | 6.029 | 0.043 |
β-Blockers | 15 (6.0) | 12 (4.9) | 17 (7.1) | 1.027 | 0.598 |
ACEI/ARB | 7 (2.8) | 8 (3.3) | 12 (5.0) | 1.828 | 0.401 |
CCB | 32 (12.8) | 34 (13.8) | 36 (14.9) | 0.470 | 0.790 |