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Table 2 Univariable analysis of new-onset heart failure

From: Higher fatty liver index is associated with increased risk of new onset heart failure in healthy adults: a nationwide population-based study in Korea

Characteristics

Value

N

HF (%)

HR

95% CI

P-value

Lower

Upper

Total

Total

308,578

2532 (0.8)

    

Sex

Female

156,540

1263 (0.8)

Reference

 

Male

152,038

1269 (0.8)

1.113

1.030

1.204

0.007

Age, year

20–34

99,774

119 (0.1)

Reference

 

35–49

130,099

637 (0.5)

3.908

3.213

4.753

< 0.001

 

50–64

65,907

1067 (1.6)

12.536

10.371

15.153

< 0.001

 

65–74

10,374

497 (4.8)

35.791

29.298

43.722

< 0.001

 

≥75

2424

212 (8.7)

75.652

60.429

94.711

< 0.001

 

Continuous

  

1.087

1.084

1.090

< 0.001

BMI, Kg/m2

< 18.5

16,662

101 (0.6)

1.075

0.870

1.328

0.505

 

18.5–19.9

33,181

177 (0.5)

0.929

0.786

1.098

0.390

 

20–22.4

89,515

625 (0.7)

Reference

 

22.5–24.9

90,961

814 (0.9)

1.115

1.005

1.238

0.041

 

≥25

78,259

815 (1.0)

1.417

1.276

1.573

< 0.001

 

Continuous

  

1.058

1.045

1.072

< 0.001

Smoking

Non-smoker

190,047

1599 (0.8)

Reference

 

Ex-smoker

35,098

320 (0.9)

0.934

0.812

1.074

0.340

 

Current-smoker

83,433

613 (0.7)

1.120

0.997

1.259

0.057

Alcohol consumption, g/week

0

149,779

1557 (1.0)

Reference

 

<=140

110,537

626 (0.6)

0.882

0.798

0.975

0.014

 

> 140

48,262

349 (0.7)

0.991

0.871

1.126

0.890

 

Continuous

  

1.000

1.000

1.000

0.960

SBP, mmHg

< 120

165,193

1019 (0.6)

Reference

 

120–139

143,385

1513 (1.1)

1.295

1.195

1.404

< 0.001

 

Continuous

  

1.013

1.010

1.017

< 0.001

DBP, mmHg

< 80

210,638

1513 (0.7)

Reference

 

80–89

97,940

1019 (1.0)

1.220

1.126

1.322

< 0.001

 

Continuous

  

1.016

1.011

1.022

< 0.001

FBS, mg/dL

<  100

246,415

1876 (0.8)

Reference

 

100–125

62,163

656 (1.1)

1.042

0.953

1.140

0.370

 

Continuous

  

1.003

1.000

1.007

0.058

Activity, MET-min/week

< 500

221,107

1871 (0.8)

    
 

500–999

65,361

453 (0.7)

0.877

0.791

0.972

0.013

 

≥1000

22,110

208 (0.9)

0.890

0.770

1.027

0.110

 

Continuous

  

1.000

0.999

1.000

0.210

Waist circumference, cm

Continuous

  

1.027

1.022

1.032

< 0.001

Total cholesterol, mg/dL

Continuous

  

1.001

1.000

1.002

< 0.001

Triglyceride, mg/dL

Continuous

  

1.001

1.000

1.001

< 0.001

HDL-cholesterol, mg/dL

Continuous

  

0.997

0.995

0.999

0.014

LDL-cholesterol, mg/dL

Continuous

  

1.000

1.000

1.000

0.290

  1. BMI body mass index, CI confidential interval, DBP diastolic blood pressure, FBS fasting blood glucose, HDL high-density lipoprotein, HF heart failure, HR hazard ration, LDL low-density lipoprotein, MET metabolic equivalent of task, SBP systolic blood pressure
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