Table 4 Associations between polymorphisms and risk of essential hypertension
SNPs | Cases, n (%) 180 (100%) | Controls, n (%) 200 (100%) | OR | CI (95%) | p values | |
|---|---|---|---|---|---|---|
rs2681472 | GG versus AG + AA, n (%) | 4 (2.2) | 4 (2.0) | 1.11 | 0.27–4.51 | 1.00 |
GG + AG versus AA, n (%) | 31 (17.2) | 38 (19.0) | 0.88 | 0.52–1.49 | 0.69 | |
A (%) | 90.3 | 89.5 | – | – | – | |
G (%) | 9.7 | 10.5 | 0.91 | 0.57–1.47 | 0.80 | |
rs17249754 | AA versus AG + GG, n (%) | 4 (2.2) | 6 (3.0) | 0.73 | 0.20–2.64 | 0.75 |
AA + AG versus GG, n (%) | 44 (24.4) | 80 (40.0) | 0.48 | 0.31–0.75 | 0.001∗ | |
G (%) | 86.7 | 78.5 | – | – | – | |
A (%) | 13.3 | 21.5 | 0.56 | 0.38–0.82 | 0.003∗ | |
rs3754777 | TT versus TC + CC, n (%) | 4 (2.0) | 4 (2.0) | 1.11 | 0.27–4.51 | 1.00 |
TT + TC versus CC, n (%) | 50 (28.0) | 54 (27.0) | 1.03 | 0.66–1.63 | 0.90 | |
C (%) | 85.0 | 85.5 | – | – | – | |
T (%) | 15.0 | 14.5 | 1.04 | 0.69–1.55 | 0.90 | |