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Table 1 Shows comparison of the data for patients that gained ROSC vs Non-ROSC patients as well for survivor’s vs Non-survivors

From: Mechanical chest compressions for cardiac arrest in the cath-lab: when is it enough and who should go to extracorporeal cardio pulmonary resuscitation?

 

All

ROSC

NO ROSC

P-value

Survivors

Non- survivors

P-value

(N = 35)

(N = 18 (51%))

(N = 17 (49%))

(N = 9 (26%))

(N = 26 (74%))

Background data (N (%) or Median (25th - 75th quartile))

 Gender (Females)

6 (17%)

3 (17%)

3 (17%)

> 0.99

1 (3%)

5 (19%)

> 0.99

 Age (years)

72 (61–78)

71 (57–75)

76 (62–78)

0.306

74 (55–80)

71 (63–78)

0.806

 AMI

10 (29%)

6 (33%)

4 (24%)

0.711

5 (56%)

5 (19%)

0.081

 Angina pectoris

3 (9%)

3 (17%)

0 (0%)

0.229

0 (0%)

3 (12%)

0.553

 Hypertension

18 (51%)

11 (61%)

7 (41%)

0.318

8 (89%)

10 (39%)

0.018

 Diabetes

7 (20%)

3 (17%)

4 (24%)

0.691

3 (33%)

4 (15%)

0.340

 Treated hypercholesterolemia

6 (17%)

3 (17%)

3 (18%)

> 0.99

2 (22%)

4 (15%)

0.635

 Stroke

5 (14%)

4 (22%)

1 (6%)

0.338

1 (11%)

5 (19%)

> 0.99

 Heart failure

3 (9%)

1 (6%)

2 (12%)

0.603

1 (11%)

2 (8%)

> 0.99

 Asthma

2 (6%)

0 (0%)

2 (12%)

0.229

0 (0%)

2 (8%)

> 0.99

 Renal disease

2 (6%)

1 (6%)

1 (6%)

> 0.99

0 (0%)

2 (8%)

> 0.99

 Valvular disease

2 (6%)

0 (0%)

2 (11%)

0.299

0 (0%)

2 (8%)

> 0.99

 Cancer

1 (3%)

0 (0%)

1 (6%)

0.486

0 (0%)

1 (4%)

> 0.99

 Smoker

7 (20%)

4 (22%)

3 (18%)

> 0.99

2 (22%)

5 (19%)

> 0.99

 X-Smoker

9 (26%)

5 (28%)

4 (24%)

> 0.99

4 (44%)

5 (19%)

0.192

Reason to be admitted to the Cath-lab (N (%))

 Planned Angiography

1 (3%)

1 (6%)

0 (0%)

> 0.99

0 (0%)

1 (4%)

> 0.99

 Planned PCI

1 (3%)

1 (6%)

0 (0%)

> 0.99

0 (0%)

1 (4%)

> 0.99

 N-STEMI

4 (11%)

3 (17%)

1 (6%)

0.603

2 (22%)

2 (8%)

0.268

 STEMI (all)

26 (74%)

10 (56%)

16 (94%)

0.018

5 (55%)

21 (81%)

0.192

 Inferior STEMI

9 (26%)

3 (17%)

6 (35%)

0.264

2 (22%)

7 (27%)

> 0.99

 Anterior STEMI

16 (46%)

6 (33%)

10 (59%)

0.181

3 (33%)

13 (50%)

0.460

 Lateral STEMI

1 (3%)

1 (6%)

0 (0%)

> 0.99

0 (0%)

1 (4%)

> 0.99

 LBBB

1 (3%)

1 (6%)

0 (0%)

> 0.99

0 (0%)

1 (4%)

> 0.99

 Acute stent occlusion.

1 (3%)

1 (6%)

0 (0%)

> 0.99

0 (0%)

1 (4%)

> 0.99

 Tamponade

1 (3%)

0 (0%)

1 (6%)

0.486

0 (0%)

1 (4%)

> 0.99

 Heart failure

1 (3%)

1 (6%)

0 (0%)

> 0.99

1 (11%)

0 (0%)

> 0.99

Culprit lesion (N (%))

 1 vessel

26 (74%)

12 (67%)

14 (82%)

0.433

5 (55%)

22 (85%)

0.162

 2 vessels

7 (20%)

4 (22%)

3 (18%)

> 0.99

4 (44%)

3 (12%)

0.055

 Left Main

12 (34%)

5 (28%)

7 (41%)

0.489

3 (33%)

9 (35%)

> 0.99

 LAD

12 (34%)

6 (33%)

6 (35%)

> 0.99

3 (33%)

9 (35%)

> 0.99

 M

2 (6%)

2 (11%)

0 (0%)

0.489

2 (22%)

0 (0%)

0.061

 CX

4 (11%)

2 (11%)

2 (12%)

> 0.99

1 (11%)

3 (12%)

> 0.99

 RCA

7 (6%)

1 (0%)

6 (12%)

0.229

1 (0%)

6 (8%)

> 0.99

 Post lateral

1 (3%)

0 (0%)

1 (6%)

0.486

0 (0%)

1 (4%)

> 0.99

 LIMA

2 (6%)

1 (6%)

1 (6%)

> 0.99

1 (11%)

1 (4%)

0.454

Rhythm causing the arrest (N (%))

 VF/VT

7 (20%)

4 (11%)

3 (9%)

> 0.99

2 (6%)

5 (14%)

> 0.99

 PEA

17 (49%)

8 (23%)

9 (26%)

0.505

3 (9%)

14 (40%)

0.460

 Asystole

4 (11%)

3 (9%)

1 (3%)

0.603

2 (6%)

2 (6%)

0.268

 Bradycardia

7 (20%)

3 (9%)

4 (11%)

0.691

2 (6%)

5 (14%)

0.268

Drugs used during resuscitation efforts (N (%) or Median (25th - 75th quartile))

 Epinephrine injection (1 mg)

23 (66%)

9 (50%)

14 (82%)

0.075

2 (22%)

21 (81%)

0.003

 Dose of Epinephrine

1 (0–3)

0 (0–1)

2 (2–5)

0.004

0 (0–0.5)

2 (1–4)

0.008

 Nor-Adrenaline

24 (69%)

11 (61%)

13 (76%)

0.471

4 (11%)

20 (77%)

0.103

 Atropine

11 (31%)

2 (11%)

9 (53%)

0.012

3 (33%)

8 (31%)

> 0.99

 Amiodarone

1 (3%)

0 (0%)

1 (6%)

0.486

0 (0%)

1 (4%)

> 0.99

 Dobutamine

11 (31%)

6 (33%)

5 (29%)

> 0.99

0 (0%)

11 (42%)

0.033

 Levosimendan

1 (3%)

1 (6%)

0 (0%)

> 0.99

0 (0%)

1 (4%)

> 0.99

 Isoprenaline

1 (3%)

0 (0%)

1 (6%)

0.486

0 (0%)

1 (4%)

> 0.99

 Buffer

1 (3%)

0 (0%)

1 (6%)

0.486

0 (0%)

1 (4%)

> 0.99

 Adenosine

1 (3%)

0 (0%)

1 (6%)

0.486

0 (0%)

1 (4%)

> 0.99

Anti-coagulants during PCI (N (%))

 Bivalirudin

19 (54%)

9 (50%)

10 (59%)

0.738

5 (55%)

14 (54%)

> 0.99

 Klopidogrel

18 (51%)

10 (56%)

8 (47%)

0.740

5 (55%)

13 (50%)

> 0.99

 Prasugrel

2 (6%)

2 (11%)

0 (0%)

0.489

2 (22%)

0 (0%)

0.061

 Heparin

29 (83%)

15 (83%)

14 (82%)

> 0.99

8 (89%)

21 (81%)

> 0.99

 Abciximab

3 (9%)

2 (11%)

1 (6%)

> 0.99

1 (11%)

2 (8%)

> 0.99

 ASA

21 (60%)

11 (61%)

10 (56%)

0.733

6 (67%)

15 (58%)

0.712

 Eptifibatide

1 (3%)

1 (6%)

0 (0%)

> 0.99

0 (0%)

1 (4%)

> 0.99

 Fondaparinux

1 (3%)

1 (6%)

0 (0%)

> 0.99

0 (0%)

1 (4%)

> 0.99

 Ticagrelor

4 (11%)

1 (6%)

3 (18%)

0.338

0 (0%)

4 (15%)

0.553

 Warfarin

3 (9%)

2 (11%)

1 (6%)

0.658

1 (11%)

2 (8%)

> 0.99

PCI results (TIMI flow) (N (%))

 3

27 (77%)

14 (78%)

13 (72%)

> 0.99

7 (78%)

20 (77%)

> 0.99

 2

1 (3%)

0 (0%)

1 (6%)

0.486

0 (0%)

1 (4%)

> 0.99

 0

4 (11%)

1 (6%)

3 (17%)

0.338

1 (11%)

0 (0%)

> 0.99

CPR data (N (%))Median (25th - 75th quartile)

 CPR prior to arrival

13 (37%)

4 (22%)

9 (53%)

0.086

0 (0%)

13 (50%)

0.001

 CPR during angiography

13 (37%)

5 (28%)

8 (47%)

0.305

3 (33%)

10 (38%)

> 0.99

 CPR during PCI

26 (74%)

12 (67%)

14 (78%)

0.443

5 (55%)

21 (81%)

0.192

 CPR time in the cath-lab

35 (12–52)

18 (10–41)

50 (33–60)

0.007

10 (8–25)

45 (30–60)

0.001

Post ROSC treatments (N (%) Median (25th - 75th quartile))

 Cooling

6 (17%)

6 (33%)

0 (0%)

0.019

1 (11%)

5 (19%)

> 0.99

 Heartmate

1 (3%)

1 (6%)

0 (0%)

> 0.99

1 (11%)

0 (0%)

> 0.99

 CABG

3 (9%)

3 (17%)

0 (0%)

0.229

1 (11%)

2 (8%)

> 0.99

 Pacing

2 (6%)

0 (0%)

2 (12%)

0.229

0 (0%)

2 (8%)

> 0.99

 IABP

12 (34%)

9 (50%)

3 (17%)

0.075

4 (44%)

8 (31%)

0.685

 Heart transplantation

1 (3%)

1 (6%)

0 (0%)

> 0.99

1 (11%)

0 (0%)

> 0.99

Physiologic parameters during CA (Median (25th - 75th quartile))

 Arterial Systolic (mmHg)

85 (71–103)

85 (80–96)

84 (48–103)a

0.593

86 (77–98)

84 (70–103)h

0.494

 Arterial Early Diastolic (mmHg)

24 (18–35)

30 (22–40)

19 (14–28)b

0.012

34 (23–40)

20 (14–30)i

0.050

 Arterial End Diastolic (mmHg)

30 (21–44)

40 (24–46)

26 (18–29)c

0.071

41 (30–43)

27 (19–44)j

0.121

 Arterial Mean (mmHg)

51 (41–58)

53 (48–59)

45 (32–58)d

0.074

54 (50–58)

46 (37–58)k

0.270

 SpO2 (mmHg)

81 (74–86)

81 (73–82)

83 (74–89)e

0.599

77 (76–81)

82 (74–87)l

0.549

 ETCO2 (mmHg)

21 (13–23)

21 (16–26)

21 (8–23)f

0.415

21 (15–26)

21 (13–23)m

0.653

 LSCOt (%)

50 (44–56)

44 (44–44)

53 (45–57)g

NA

NA

48 (44–56)n

NA

 RScot (%)

55 (49–58)

38 (38–38)

58 (55–59) g

NA

NA

52 (49–58) n

NA

 AScot (%)

54 (48–57)

41 (41–41)

56 (54–57) g

NA

NA

51 (48–57) n

NA

  1. AMI acute myocardial infarction, PCI percutaneous coronary intervention, N-STEMI non ST-elevation myocardial infarction, STEMI ST-elevation myocardial infarction, LBBB left bundle branch block, LAD left anterior descendent artery, M marginal branch, Cx circumflex artery, RCA right coronary artery, LIMA left internal mammary artery, VF ventricular fibrillation, VT ventricular tachycardia, PEA pulseless electrical activity, SR sinus rhythm, ASA acetyl salicylic acid, CPR cardio-pulmonary resuscitation, CABG coronary artery by-pass grafting, IABP intra aortic balloon counter pulsation,, SpO2 Index finger saturation, ETCO2 end tidal carbon dioxide, LSctO2 left cerebral tissue oximetry, RSctO2 left cerebral tissue oximetry, ASctO2 Average of left and right cerebral tissue oximetry and NA Not Applicable
  2. a(ROSC N = 18 and No ROSC N = 16), b (ROSC N = 18 and No ROSC N = 15), c(ROSC N = 18 and No ROSC N = 15), d (ROSC N = 14 and No ROSC N = 8), e (ROSC N = 18 and No ROSC N = 15), f (ROSC N = 7 and No ROSC N = 11), g (ROSC N = 1 and No ROSC N = 5), h (Survivors N = 9 and Dead N = 25), i (Survivors N = 7 and Dead N = 24), j (Survivors N = 7 and Dead N = 15), k (Survivors N = 8 and Dead N = 22), l (Survivors N = 7 and Dead N = 15), m (Survivors N = 4 and Dead N = 15) and n (Survivors N = 0 and Dead N = 6)
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