Impact of liver damage on blood-borne variables and pulmonary hemodynamic responses to hypoxia and hyperoxia in anesthetized rats

Table 2 The comparison of the experimental variables in the CBDL+PPVL versus CBDL models

CBD + PPVL	Effect	CBDL	Effect
Liver damage ↑↑	Liver dysfunction	Liver damage ↑↑	Liver dysfunction
Liver enzymes ↑↑	Liver dysfunction	Liver enzymes ↑↑	Liver dysfunction
WBC ↑↑	Systemic Inflammation	WBC ↑	Systemic inflammation
PLT ↓↓	Vascular thrombosis	PLT ↔	No change
Basal RVSP ↑↑		Basal RVSP ↑
HPV	No response	HPV	No response
ROS ↑	Systemic Inflammation	ROS ↑	Systemic Inflammation
PaO₂ ↓	Impairment of gas exchange	PaO₂ ↓	Little effect
PaO₂/FIO₂ ↓	Impairment of gas exchange	PaO₂/FIO₂ ↓	Little effect
Estradiol ↑		Estradiol ↑↑

ISSN: 1471-2261