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Table 2 The comparison of the experimental variables in the CBDL+PPVL versus CBDL models

From: Impact of liver damage on blood-borne variables and pulmonary hemodynamic responses to hypoxia and hyperoxia in anesthetized rats

CBD + PPVL Effect CBDL Effect
Liver damage ↑↑ Liver dysfunction Liver damage ↑↑ Liver dysfunction
Liver enzymes ↑↑ Liver dysfunction Liver enzymes ↑↑ Liver dysfunction
WBC ↑↑ Systemic Inflammation WBC ↑ Systemic inflammation
PLT ↓↓ Vascular thrombosis PLT ↔ No change
Basal RVSP ↑↑   Basal RVSP ↑  
HPV No response HPV No response
ROS ↑ Systemic Inflammation ROS ↑ Systemic Inflammation
PaO2 Impairment of gas exchange PaO2 Little effect
PaO2/FIO2 Impairment of gas exchange PaO2/FIO2 Little effect
Estradiol ↑   Estradiol ↑↑