Comprehensive microRNA profiling reveals potential augmentation of the IL1 pathway in rheumatic heart valve disease

Lu, Qiyu; Sun, Yi; Duan, Yuyin; Li, Bin; Xia, Jianming; Yu, Songhua; Zhang, Guimin

doi:10.1186/s12872-018-0788-2

Table 1 Coordinately regulated miRNAs in RHD patients with mitral valve stenosis and their fold of change

From: Comprehensive microRNA profiling reveals potential augmentation of the IL1 pathway in rheumatic heart valve disease

miRNA Name	log2Ratio(LM1/NC)	log2Ratio(LM2/NC)	log2Ratio(S1/NC)	log2Ratio(S2/NC)
hsa-miR-15b-3p	−2.3981	−1.1215	− 1.6477	− 11.3676
hsa-miR-29b-3p	− 11.0347	− 1.2671	−2.0974	− 11.0347
hsa-miR-29b-1-5p	− 10.2868	− 1.2696	− 2.1042	− 11.0238
hsa-miR-15b-5p	− 2.4033	−1.1285	− 1.6580	−10.9747
hsa-miR-374a-5p	− 6.7934	− 2.6911	−2.1515	− 10.9111
hsa-miR-29b-2-5p	−10.2882	− 1.2743	− 2.1146	− 10.4946
hsa-miR-374a-3p	− 6.7395	− 2.6759	−2.1522	− 9.9063
hsa-miR-3613-3p	− 9.1652	−1.2656	− 3.0141	− 9.9022
hsa-miR-3613-5p	− 9.8992	−1.2626	− 3.0677	− 9.8992
hsa-miR-219a-5p	− 9.2885	− 9.2885	−2.7493	− 9.2885
hsa-miR-219a-1-3p	− 9.2862	− 9.2862	−2.7713	−9.2862
hsa-miR-29c-5p	−9.1384	− 6.8165	− 1.0305	− 9.1384
hsa-miR-29c-3p	−8.3756	− 7.5276	− 1.0688	− 9.1126
hsa-miR-199b-5p	− 6.5267	− 2.1762	− 2.5637	−8.7706
hsa-miR-769-5p	− 6.8790	−1.1259	−8.0854	− 8.6159
hsa-miR-769-3p	−8.5862	−1.0881	− 8.5862	− 8.5862
hsa-miR-3177-5p	− 8.5175	− 8.5175	−1.2611	−8.5175
hsa-miR-3177-3p	−8.5016	−8.5016	−1.2172	− 8.5016
hsa-miR-1260a	−8.9245	−1.3404	−1.8813	− 8.3940
hsa-miR-1260b	−8.2931	− 8.2931	−8.2931	− 8.2931
hsa-miR-514a-3p	−8.2368	− 8.2368	−8.2368	− 8.2368
hsa-miR-1323	−8.1384	− 8.1384	−8.1384	− 8.1384
hsa-miR-3150a-3p	− 7.8704	− 7.8704	−1.0774	− 7.8704
hsa-miR-3150b-5p	− 7.8642	− 7.8642	− 1.0712	− 7.8642
hsa-miR-3150b-3p	− 7.8580	− 7.8580	−1.0265	− 7.8580
hsa-miR-3150a-5p	− 7.8517	− 7.8517	−1.0007	− 7.8517
hsa-miR-514a-5p	−8.2416	− 8.2416	− 8.2416	− 7.7111
hsa-miR-4454	−7.5715	− 7.5715	− 7.5715	−7.5715
hsa-miR-3908	−7.4197	−7.4197	− 7.4197	−7.4197
hsa-miR-6805-5p	−7.4113	−7.4113	− 7.4113	−7.4113
hsa-miR-6805-3p	−7.3856	−7.3856	− 7.3856	−7.3856
hsa-miR-205-5p	−7.3249	−7.3249	− 7.3249	−7.3249
hsa-miR-329-3p	−7.3068	−7.3068	− 7.3068	−7.3068
hsa-miR-205-3p	−7.2977	−7.2977	− 7.2977	−7.2977
hsa-miR-329-5p	−5.5607	−7.2977	−7.2977	− 7.2977
hsa-miR-181d-5p	−7.1832	− 7.1832	− 6.6527	−7.1832
hsa-miR-181d-3p	−7.1733	−7.1733	− 7.1733	−7.1733
hsa-miR-3940-3p	−7.1733	−7.1733	− 7.1733	−7.1733
hsa-miR-136-3p	−7.1632	−7.1632	− 7.1632	−7.1632
hsa-miR-3940-5p	−7.1632	−7.1632	− 7.1632	−7.1632
hsa-miR-642a-3p	−7.1632	−7.1632	− 7.1632	− 7.1632
hsa-miR-136-5p	− 7.1531	−7.1531	− 7.1531	−7.1531
hsa-miR-581	−7.1531	−7.1531	− 7.1531	−7.1531
hsa-miR-642b-3p	−7.1531	−7.1531	− 7.1531	−7.1531
hsa-miR-642b-5p	−6.4162	−7.1531	−7.1531	− 7.1531
hsa-miR-642a-5p	−7.1441	− 7.1441	−7.1441	− 7.1441
hsa-miR-4999-5p	−7.1339	− 7.1339	−7.1339	− 7.1339
hsa-miR-4999-3p	−7.1132	− 7.1132	−7.1132	− 7.1132
hsa-miR-590-5p	−6.9937	− 6.9937	− 6.9937	− 6.9937
hsa-miR-3122	− 7.5096	− 7.5096	− 7.5096	−6.9790
hsa-miR-3164	−6.9242	−6.9242	− 6.9242	−6.9242
hsa-miR-590-3p	−6.9002	−6.9002	− 6.9002	−6.9002
hsa-miR-6884-3p	−6.9002	−6.9002	− 6.9002	−6.9002
hsa-miR-6884-5p	−6.8881	−6.8881	− 6.8881	−6.8881
hsa-miR-1270	−6.7755	−6.7755	− 6.7755	−6.7755
hsa-miR-4676-5p	−6.4374	−6.4374	− 6.4374	−6.4374
hsa-miR-4511	−6.4207	−6.4207	− 6.4207	−6.4207
hsa-miR-4676-3p	−6.4207	−6.4207	− 6.4207	−6.4207
hsa-miR-6516-5p	−6.4037	−6.4037	− 6.4037	−6.4037
hsa-miR-199b-3p	−5.9433	−2.1902	− 2.6096	−6.3637
hsa-miR-1538	−6.3517	−6.3517	− 6.3517	−6.3517
hsa-miR-6516-3p	−6.3517	−6.3517	− 6.3517	−6.3517
hsa-miR-548ar-5p	−6.3159	−6.3159	− 6.3159	−6.3159
hsa-miR-548ar-3p	−6.2977	−6.2977	− 6.2977	−6.2977
hsa-miR-641	−5.9255	−5.9255	− 5.9255	− 5.9255
hsa-miR-3675-3p	− 5.7489	−5.7489	−3.5969	− 5.7489
hsa-miR-3675-5p	−5.7219	− 5.7219	−4.1369	−5.7219
hsa-miR-3200-3p	−5.5783	−5.5783	− 5.5783	−5.5783
hsa-miR-3200-5p	−5.5478	−5.5478	− 5.5478	−5.5478
hsa-miR-4523	−4.9015	−4.9015	− 4.9015	−4.9015
hsa-miR-203a-5p	−3.2221	−4.5280	−1.0208	−4.8728
hsa-miR-141-5p	−4.8613	−5.1832	−5.5983	−4.7093
hsa-miR-203a-3p	−2.9480	−5.1373	− 1.1112	−4.6747
hsa-miR-3909	−4.3847	−4.3847	− 4.3847	−4.3847
hsa-miR-203b-3p	−2.7659	−3.8329	−1.0359	−4.3682
hsa-miR-141-3p	−3.6781	−7.2224	−5.0704	−4.1635
hsa-miR-95-5p	−3.4150	−4.3479	−3.0525	−4.1520
hsa-miR-95-3p	−3.1872	−4.0941	−3.3392	− 3.8653
hsa-miR-532-3p	−1.5264	− 1.8552	− 1.1227	−2.7619
hsa-miR-532-5p	−1.5236	− 1.8643	−1.1235	−2.7513
hsa-miR-206	−1.0095	−1.9317	− 1.3186	−2.2835
hsa-miR-181b-3p	−9.8486	−2.0724	−1.7331	−2.2504
hsa-miR-181b-5p	−9.8549	−2.0786	−1.7469	−2.2459
hsa-miR-4508	−9.2885	−2.4291	−2.0458	− 2.2236
hsa-miR-215-5p	−1.8820	−2.5874	−1.5617	− 1.9192
hsa-miR-215-3p	−1.8845	−2.5652	− 1.5671	−1.9189
hsa-miR-6130	−7.1027	−3.6288	− 3.5177	−1.6216
hsa-miR-142-5p	−1.7941	−1.4349	− 1.0817	−1.4517
hsa-miR-142-3p	−1.7973	−1.4265	− 1.0828	−1.3575
hsa-miR-766-3p	−8.8234	−8.8234	−1.8474	−1.2351
hsa-miR-766-5p	−8.8202	− 8.8202	−1.8442	− 1.2319
hsa-miR-7110-5p	2.9310	1.8419	1.7966	2.4297
hsa-miR-7110-3p	2.9666	1.2266	1.8382	2.4615
hsa-miR-1-5p	5.6517	4.2842	3.9360	2.6203
hsa-miR-1-3p	5.6585	4.3807	3.8186	2.6229
hsa-miR-1246	2.0377	1.9982	2.5022	2.6648
hsa-miR-1290	1.4055	1.5543	1.9796	2.7608
hsa-miR-122-5p	1.5321	2.5392	2.5282	3.4902
hsa-miR-122-3p	1.5323	2.5394	2.5284	3.4904
hsa-miR-3591-3p	1.5433	2.5394	2.5567	3.4941
hsa-miR-3591-5p	1.5425	2.5393	2.5575	3.4942
hsa-miR-224-5p	2.1725	5.9816	6.0851	6.9059
hsa-miR-134-5p	10.0779	8.6974	7.3389	8.7835
hsa-miR-134-3p	10.0734	8.7008	7.3259	8.7969

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