Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. Burden of valvular heart diseases: a population-based study. Lancet. 2006;368(9540):1005–11.
Article
PubMed
Google Scholar
Iung B, Baron G, Butchart EG, Delahaye F, Gohlke-Barwolf C, Levang OW, Tornos P, Vanoverschelde JL, Vermeer F, Boersma E, et al. A prospective survey of patients with valvular heart disease in Europe: the euro heart survey on valvular heart disease. Eur Heart J. 2003;24(13):1231–43.
Tribouilloy CM, Enriquez-Sarano M, Schaff HV, Orszulak TA, Bailey KR, Tajik AJ, Frye RL. Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation : rationale for optimizing surgical indications. Circulation. 1999;99(3):400–5.
Article
CAS
PubMed
Google Scholar
Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Baron-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, et al. Guidelines on the management of valvular heart disease (version 2012). Eur Heart J. 2012;33(19):2451–96.
Article
PubMed
Google Scholar
Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP 3rd, Guyton RA, O'Gara PT, Ruiz CE, Skubas NJ, Sorajja P, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association task force on practice guidelines. J Am Coll Cardiol. 2014;63(22):e57–185.
Article
PubMed
Google Scholar
Quintana E, Suri RM, Thalji NM, Daly RC, Dearani JA, Burkhart HM, Li Z, Enriquez-Sarano M, Schaff HV. Left ventricular dysfunction after mitral valve repair-the fallacy of “normal” preoperative myocardial function. J Thorac Cardiovasc Surg. 2014;148(6):2752–60.
Article
PubMed
Google Scholar
David TE, Armstrong S, McCrindle BW, Manlhiot C. Late outcomes of mitral valve repair for mitral regurgitation due to degenerative disease. Circulation. 2013;127(14):1485–92.
Article
PubMed
Google Scholar
De Bonis M, Lapenna E, Taramasso M, La Canna G, Buzzatti N, Pappalardo F, Alfieri O. Very long-term durability of the edge-to-edge repair for isolated anterior mitral leaflet prolapse: up to 21 years of clinical and echocardiographic results. J Thorac Cardiovasc Surg. 2014;148(5):2027–32.
Article
PubMed
Google Scholar
Kang DH, Kim JH, Rim JH, Kim MJ, Yun SC, Song JM, Song H, Choi KJ, Song JK, Lee JW. Comparison of early surgery versus conventional treatment in asymptomatic severe mitral regurgitation. Circulation. 2009;119(6):797–804.
Article
PubMed
Google Scholar
Suri RM, Vanoverschelde JL, Grigioni F, Schaff HV, Tribouilloy C, Avierinos JF, Barbieri A, Pasquet A, Huebner M, Rusinaru D, et al. Association between early surgical intervention vs watchful waiting and outcomes for mitral regurgitation due to flail mitral valve leaflets. JAMA. 2013;310(6):609–16.
Rosenhek R, Rader F, Klaar U, Gabriel H, Krejc M, Kalbeck D, Schemper M, Maurer G, Baumgartner H. Outcome of watchful waiting in asymptomatic severe mitral regurgitation. Circulation. 2006;113(18):2238–44.
Article
PubMed
Google Scholar
David TE. Durability of mitral valve repair for mitral regurgitation due to degenerative mitral valve disease. Ann Cardiothorac Surg. 2015;4(5):417–21.
PubMed
PubMed Central
Google Scholar
Gillam LD, Schwartz A. Primum non nocere: the case for watchful waiting in asymptomatic "severe" degenerative mitral regurgitation. Circulation. 2010;121(6):813–21. Discussion 821.
Enriquez-Sarano M, Sundt TM 3rd. Early surgery is recommended for mitral regurgitation. Circulation. 2010;121(6):804–11. Discussion 812.
Agricola E, Galderisi M, Oppizzi M, Schinkel AFL, Maisano F, De Bonis M, Margonato A, Maseri A, Alfieri O. Pulsed tissue Doppler imaging detects early myocardial dysfunction in asymptomatic patients with severe mitral regurgitation. Heart. 2004;90(4):406–10.
Article
CAS
PubMed
PubMed Central
Google Scholar
Magne J, Mahjoub H, Pierard LA, O'Connor K, Pirlet C, Pibarot P, Lancellotti P. Prognostic importance of brain natriuretic peptide and left ventricular longitudinal function in asymptomatic degenerative mitral regurgitation. Heart. 2012;98(7):584–91.
Article
CAS
PubMed
Google Scholar
Le Tourneau T, Messika-Zeitoun D, Russo A, Detaint D, Topilsky Y, Mahoney DW, Suri R, Enriquez-Sarano M. Impact of left atrial volume on clinical outcome in organic mitral regurgitation. J Am Coll Cardiol. 2010;56(7):570–8.
Article
PubMed
Google Scholar
Le Tourneau T, Deswarte G, Lamblin N, Foucher-Hossein C, Fayad G, Richardson M, Polge AS, Vannesson C, Topilsky Y, Juthier F, et al. Right ventricular systolic function in organic mitral regurgitation: impact of biventricular impairment. Circulation. 2013;127(15):1597–608.
Article
PubMed
Google Scholar
Song Y, Lee S, Kwak YL, Shim CY, Chang BC, Shim JK. Tissue Doppler imaging predicts left ventricular reverse remodeling after surgery for mitral regurgitation. Annals of Thoracic Surgery. 2013;96(6):2109–15.
Article
PubMed
Google Scholar
Mewton N, Liu CY, Croisille P, Bluemke D, Lima JAC. Assessment of myocardial fibrosis with cardiovascular magnetic resonance. J Am Coll Cardiol. 2011;57(8):891–903.
Article
PubMed
Google Scholar
Fuster V, Danielson MA, Robb RA, Broadbent JC, Brown AL, Elveback LR. Quantitation of left ventricular myocardial fiber hypertrophy and interstitial tissue in human hearts with chronically increased volume and pressure overload. Circulation. 1977;55(3):504–8.
Article
CAS
PubMed
Google Scholar
Edwards NC, Moody WE, Yuan MS, Weale P, Neal D, Townend JN, Steeds RP. Quantification of left ventricular interstitial fibrosis in asymptomatic chronic primary degenerative mitral regurgitation. Circ-Cardiovasc Imaging. 2014;7(6):946–53.
Article
PubMed
Google Scholar
White SK, Sado DM, Fontana M, Banypersad SM, Maestrini V, Flett AS, Piechnik SK, Robson MD, Hausenloy DJ, Sheikh AM, et al. T1 mapping for myocardial extracellular volume measurement by CMR: bolus only versus primed infusion technique. JACC Cardiovascular Imaging. 2013;6(9):955–62.
Iles LM, Ellims AH, Llewellyn H, Hare JL, Kaye DM, McLean CA, Taylor AJ. Histological validation of cardiac magnetic resonance analysis of regional and diffuse interstitial myocardial fibrosis. European heart journal cardiovascular Imaging. 2015;16(1):14–22.
Article
PubMed
Google Scholar
Kammerlander AA, Marzluf BA, Zotter-Tufaro C, Aschauer S, Duca F, Bachmann A, Knechtelsdorfer K, Wiesinger M, Pfaffenberger S, Greiser A, et al. T1 mapping by CMR imaging from histological validation to clinical implication. JACC Cardiovascular Imaging. 2016;9(1):14–23.
Wong TC, Piehler K, Meier CG, Testa SM, Klock AM, Aneizi AA, Shakesprere J, Kellman P, Shroff SG, Schwartzman DS, et al. Association between extracellular matrix expansion quantified by cardiovascular magnetic resonance and short-term mortality. Circulation. 2012;126(10):1206–16.
Article
PubMed
PubMed Central
Google Scholar
Schelbert EB, Piehler KM, Zareba KM, Moon JC, Ugander M, Messroghli DR, Valeti US, Chang CCH, Shroff SG, Diez J, et al. Myocardial fibrosis quantified by extracellular volume is associated with subsequent hospitalization for heart failure, Death, or both across the Spectrum of ejection fraction and heart failure stage. J Am Heart Assoc. 2015;4(12)
Miller CA, Naish JH, Bishop P, Coutts G, Clark D, Zhao S, Ray SG, Yonan N, Williams SG, Flett AS, et al. Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume. Circ Cardiovasc Imaging. 2013;6(3):373–83.
Article
PubMed
Google Scholar
Edwards NC, Yuan M, Good IK, Moody WE, Steeds RP. Optimum management of asymptomatic moderate-severe degenerative mitral regurgitation: a role for T1 mapping in risk stratification? Journal of Cardiovascular Magnetic Resonance Imaging. 2014;16(S1):238.
Goldstein D, Moskowitz AJ, Gelijns AC, Ailawadi G, Parides MK, Perrault LP, Hung JW, Voisine P, Dagenais F, Gillinov AM, et al. Two-Year outcomes of surgical treatment of severe ischemic mitral regurgitation. N Engl J Med. 2016;374(4):344–53.
Article
CAS
PubMed
Google Scholar
Maceira AM, Prasad SK, Khan M, Pennell DJ. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2006;8(3):417–26.
Article
CAS
PubMed
Google Scholar
Moon JC, Messroghli DR, Kellman P, Piechnik SK, Robson MD, Ugander M, Gatehouse PD, Arai AE, Friedrich MG, Neubauer S, et al. Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR working Group of the European Society of Cardiology consensus statement. J Cardiovasc Magn Reson. 2013;15:92
Kehr E, Sono M, Chugh SS, Jerosch-Herold M. Gadolinium-enhanced magnetic resonance imaging for detection and quantification of fibrosis in human myocardium in vitro. The international journal of cardiovascular imaging. 2008;24(1):61–8.
Article
PubMed
Google Scholar
Ross RM. ATS/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med. 2003;167(10):1451. author reply 1451
Article
PubMed
Google Scholar
Beaver WL, Wasserman K, Whipp BJ. A new method for detecting anaerobic threshold by gas-exchange. J Appl Physiol. 1986;60(6):2020–7.
CAS
PubMed
Google Scholar
Wharton G, Steeds R, Allen J, Phillips H, Jones R, Kanagala P, Lloyd G, Masani N, Mathew T, Oxborough D, et al. A minimum dataset for a standard adult transthoracic echocardiogram: a guideline protocol from the British society of echocardiography. Echo Res Pract. 2015;2(1):G9–G24.
Borg AN, Harrison JL, Argyle RA, Ray SG. Left ventricular torsion in primary chronic mitral regurgitation. Heart. 2008;94(5):597–603.
Article
CAS
PubMed
Google Scholar
Liu B, Edwards NC, Ray S, Steeds RP. Timing surgery in mitral regurgitation: defining risk and optimising intervention using stress echocardiography. Echo Res Pract. 2016;3(4):R45–55.
Zoghbi WA, Adams D, Bonow RO, Enriquez-Sarano M, Foster E, Grayburn PA, Hahn RT, Han Y, Hung J, Lang RM, et al. Recommendations for noninvasive evaluation of native Valvular regurgitation: a report from the American Society of Echocardiography developed in collaboration with the Society for Cardiovascular Magnetic Resonance. J Am Soc Echocardiogr. 2017;30(4):303–71.
Article
PubMed
Google Scholar
Algra A, Tijssen JGP, Roelandt J, Pool J, Lubsen J. QT interval variables from 24-hour electrocardiography and the 2-Year risk of sudden-Death. Br Heart J. 1993;70(1):43–8.
Hansen L, Winkel S, Kuhr J, Bader R, Bleese N, Riess FC. Factors influencing survival and postoperative quality of life after mitral valve reconstruction. Eur J Cardiothorac Surg. 2010;37(3):635–44.
Article
PubMed
Google Scholar
Schiros CG, Dell'Italia LJ, Gladden JD, Clark D, Aban I, Gupta H, Lloyd SG, McGiffin DC, Perry G, Denney TS et al: Magnetic resonance imaging with 3-dimensional analysis of left ventricular remodeling in isolated mitral regurgitation implications beyond dimensions. Circulation 2012; 125(19):2334-42.
Enriquez-Sarano M, Suri RM, Clavel MA, Mantovani F, Michelena HI, Pislaru S, Mahoney DW, Schaff HV. Is there an outcome penalty linked to guideline-based indications for valvular surgery? Early and long-term analysis of patients with organic mitral regurgitation. J Thorac Cardiovasc Surg. 2015;150(1):50–8.
Article
PubMed
Google Scholar