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Table 1 Targets of coagulation inhibitors

From: Endothelial cell control of thrombosis

Inhibitor

Principal target(s)

Antithrombin

Thrombin, fXa, fIXa, fXIa, fXIIa

TFPI

fXa, TF/fVIIa

Heparin cofactor II

Thrombin

C1 inhibitor

fXIa, fXIIa, kallikrein

Protein C pathway

Thrombin

  1. Abbreviations: TFPI tissue factor pathway inhibitor