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Table 4 Adjusted hazards for ACS re-hospitalization by clopidogrel duration (9, 12, 15 months); DES subgroup

From: Duration of dual antiplatelet therapy following percutaneous coronary intervention on re-hospitalization for acute coronary syndrome

DES-subgroup analysis

Unadjusted hazard ratio

p*

Adjusted hazard ratio

p*

HR (95% CI)

HR (95% CI)

Clopidogrel use for ≥ 9 mo

0.71 (0.47-1.07)

0.10

0.68 (0.44-1.06) *

0.09

Clopidogrel use for ≥ 12 mo

0.58 (0.35-0.98)

0.04

0.52 (0.29-0.92) †

0.02

Clopidogrel use for ≥ 15 mo

0.91 (0.46-1.82)

0.79

0.76 (0.37-1.56) ‡

0.45

  1. *Adjusted for comorbidities (hypertension, DM uncontrolled, myocardial infarction), use of aspirin, NSAID, multivessel PCI, number of stents, total stent length > 45 mm, minimum of stent diameter < 2.5 mm, ostium lesion, bifurcation lesion, LM lesion.
  2. † Adjusted for comorbidities (hypertension, DM uncontrolled, GI bleeding/ulcer, myocardial infarction), use of aspirin, NSAID, cholesterol, multivessel PCI, number of stents, total stent length > 45 mm, minimum of stent diameter < 2.5 mm, ostium lesion, bifurcation lesion, LM lesion.
  3. ‡ Adjusted for comorbidities (hypertension, DM uncontrolled, GI bleeding/ulcer, myocardial infarction), use of NSAID, multivessel PCI, number of stents, total stent length > 45 mm, minimum of stent diameter < 2.5 mm, ostium lesion, bifurcation lesion, LM lesion.