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Table 2 PIIINP, PINP, PICP, and TGF-β1 blood levels

From: Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl terminal peptide and TGF-β1 levels in serum of patients with atrial fibrillation

  PeAF + VHD (n = 30) PaAF + VHD (n = 30) SR + VHD (n = 30) SR + CHD (n = 10)
PIIINP (ng/ml) 88.03 ± 46.08b,c 72.96 ± 43.30d 52.50 ± 29.32e 14.09 ± 2.732
PINP (ng/ml) 45.41 ± 42.17c 34.82 ± 28.60 18.95 ± 17.34 6.940 ± 3.007
TGF-β1 (pg/ml) 49.01 ± 28.67a,b,c 27.96 ± 13.16d 24.09 ± 14.10 11.43 ± 2.695
PICP (ng/ml) 43.42 ± 3.699a,b,c 36.06 ± 7.710d 29.75 ± 9.241e 12.52 ± 3.033
  1. Data are presented as n or mean ± standard deviation.
  2. CHD, Congenital heart disease; PaAF, Paroxysmal atrial fibrillation; PeAF, Persistent atrial fibrillation; PICP, carboxyl-terminal peptide from pro-collagen I; PINP, N-terminal type I procollagen propeptides; PIIINP, N-terminal type III procollagen propeptides; SR, Sinus rhythm; VHD, Valvular heart disease.
  3. aPeAF + VHD vs. PaAF + VHD; P < 0.05. bPeAF + VHD vs. SR + VHD; P < 0.05. cPeAF + VHD vs. SR + CHD; P < 0.05. dPaAF + VHD vs. SR + CHD; P < 0.05. eSR + VHD vs. SR + CHD; P < 0.05.