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Table 3 Cox regression with the outcome having at least one hospital admission during the study period of one year adjusted for HF-subgroups, kidney function and NT-proBNP levels

From: Factors affecting hospitalization and mortality in a retrospective study of elderly patients with heart failure

 

HR

95.0% CI for HR

p-value

Lower

Upper

HF-subgroups

   

0.01

HFpEF

Reference

   

HFmrEF

1.07

0.93

1.22

 

HFrEF

1.10

0.97

1.26

 

HF-ndEF

1.21

1.08

1.35

 

Kidney function

   

< 0.001

> 60 ml/min

Reference

   

30–60 ml/min

0.97

0.88

1.06

 

< 30 ml/min

1.39

1.21

1.60

 

NT-proBNP levels

   

< 0.001

HF unlikely

Reference

   

Grey zone

1.23

1.02

1.49

 

HF likely

1.71

1.42

2.06

 

Comorbidities

    

Cardiovascular disease

1.15

1.06

1.26

0.001

Diabetes

1.14

1.03

1.26

0.01

COPD

1.19

1.06

1.34

0.003

Pharmacotherapy

    

BB and RAASi

0.80

0.73

0.88

< 0.001

Healthcare utilization

    

Primary care physician

0.35

0.31

0.40

< 0.001

  1. Note NT-proBNP = natriuretic terminal pro brain natriuretic peptide, HF = Heart failure, HR = Hazard ratio, CI = confidence interval, HFrEF = heart failure with reduced ejection fraction, HFmrEF = heart failure with mildly reduced ejection fraction, HFpEF = heart failure with preserved ejection fraction, HFndEF = heart failure with no defined ejection fraction, COPD = chronic obstructive pulmonary disease, BB = betablockers, RAASi = renin-angiotensin-aldosterone-system inhibition (includes Angiotensin-converting-enzyme inhibitors, Angiotensin receptor blockers and Angiotensin receptor neprilysin)