Fig. 1From: HAPLN1 knockdown inhibits heart failure development via activating the PKA signaling pathwayThe distribution of DEGs be visualized using the volcano plots. (A) The volcano plot of GSE116250 dataset, including 182 DEGs (130 up-regulated genes and 52 down-regulated genes). (B) The volcano plot of GSE135055 dataset, comprising 171 DEGs (121 up-regulated genes and 50 down-regulated genes). The red dots represent the upregulated DEGs, the blue dots represent the downregulated DEGs, and the black dots represent genes with no significant differences. (C-D). The heatmap displayed the expression levels of the top 30 DEGs identified from the datasets GSE116250 and GSE135055, respectively. The change in color from red to blue indicates a progressive decrease in gene expression in the sample. Each bioinformatics analysis was performed independently three times. Notes DEGs, differently expressed genesBack to article page