| Whole population n = 506 | ObstrCAD-NO n = 258 | ObstrCAD-YES n = 178 | p-value | InducibleMI-NO n = 160 | InducibleMI-YES n = 165 | p-value |
---|---|---|---|---|---|---|---|
Clinical characteristics | |||||||
 Age, years | 62.0 ± 9.2 | 60.3 ± 8.4 | 64.6 ± 8.6 |  < 0.0001 | 60.5 ± 9.9 | 63.9 ± 9.3 | 0.0006 |
 Male gender | 62 | 52 | 81 |  < 0.0001 | 54 | 68 | 0.01 |
 Family history of CAD | 49 | 51 | 42 | ns | 57 | 46 | ns |
 LVEF | 60.7 ± 5.1 | 61.9 ± 4.9 | 59.5 ± 5.1 | 0.0001 | 61.1 ± 4.9 | 60.4 ± 5.2 | ns |
Symptoms | |||||||
 Typical Angina | 40 | 33 | 53 |  < 0.0001 | 41 | 51 | ns |
Medications | |||||||
 Antihypertensives and Anti-ischemics | 69 | 69 | 70 | ns | 68 | 65 | ns |
 Aspirin | 44 | 46 | 43 | ns | 48 | 48 | ns |
 Statins | 38 | 39 | 37 | ns | 26 | 28 | ns |
 Anti diabetic therapy | 16 | 18 | 16 | ns | 16 | 19 | ns |
Modifiable Risk factors | |||||||
 High SBPa | 64 | 63 | 69 | ns | 62 | 70 | ns |
 High LDL-C | 48 | 51 | 43 | ns | 61 | 48 | 0.02 |
 Smoking | 20 | 17 | 24 | ns | 19 | 22 | ns |
 High BMIa | 20 | 23 | 16 | ns | 25 | 11 | 0.0009 |
 High FPGa | 55 | 51 | 60 | ns | 56 | 50 | ns |
 Low HDL-Ca | 28 | 22 | 40 |  < 0.0001 | 18 | 28 | 0.01 |
 High TGa | 25 | 22 | 29 | ns | 24 | 28 | ns |
 Metabolic Syndrome | 30 | 26 | 36 | 0.04 | 30 | 27 | ns |
Laboratory clinical-chemistry data | |||||||
 Total-C, mg/dL | 190.0 ± 48.1 | 196.7 ± 48.5 | 177.1 ± 47.5 |  < 0.0001 | 204.8 ± 43.5 | 190.5 ± 44.5 | 0.003 |
 LDL-C, mg/dL | 113 ± 39 | 117 ± 40 | 107 ± 38 | 0.0009 | 124 ± 35 | 114 ± 41 | 0.007 |
 HDL-C, mg/dL | 52.9 ± 16.9 | 57.5 ± 18.2 | 45.4 ± 13.3 |  < 0.0001 | 56.9 ± 16.7 | 53.0 ± 18.1 | 0.009 |
 TG, mg/dL | 118.0 ± 64.0 | 112.3 ± 57.5 | 123.2 ± 65.4 | ns | 119.5 ± 66.8 | 122.3 ± 67.0 | ns |
 ApoA1, mg/dL | 132 ± 41 | 142 ± 44 | 139 ± 37 |  < 0.0001 | 134 ± 41 | 132 ± 42 | ns |
 TG/HDL-C | 2.6 ± .1.8 | 2.3 ± 1.7 | 3.0 ± 1.9 |  < 0.0001 | 2.4 ± 1.7 | 2.7 ± 1.9 | ns |
 Glucose, mg/dL | 105.0 ± 29.1 | 103.7 ± 24.8 | 107.3 ± 32.0 | ns | 108.8 ± 31.3 | 103.7 ± 33.7 | ns |
 Insulin, μUI/mL | 9.8 ± 9.7 | 9.6 ± 8.2 | 10.5 ± 11.0 | ns | 10.4 ± 10.0 | 9.4 ± 8.9 | 0.05 |
 HOMA Index | 2.8 ± 3.8 | 2.6 ± 2.4 | 2.8 ± 3.6 | ns | 3.1 ± 4.4 | 2.6 ± 2.8 | 0.02 |
Genotype distribution | |||||||
 Glu/Glu | 50 | 48 | 50 | ns | 59 | 42 | 0.01 |
 Glu/Asp | 41 | 43 | 39 | 33 | 48 | ||
 Asp/Asp | 9 | 9 | 11 | 8 | 10 | ||
 Glu/Glu | 50 | 47 | 50 | ns | 59 | 42 | 0.003 |
 Asp | 50 | 53 | 50 | 41 | 58 |