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Table 2 Statistical analysis of diagnostic biomarkers: discovery phase

From: Analysis of differential metabolites in serum metabolomics of patients with aortic dissection

Metabolites

log2(FC)

Retention time (min)

VIP

P-value

adj.P-value

FC

Dolichyl b-D-glucosyl phosphate

1.2323

4.9621

2.5299

0.000213

0.00424

2.3505

LysoPC(20:1(11Z))

-0.5924

12.3464

2.1241

8.21E-05

0.0024

0.66333

LysoPC(24:1(15Z))

0.2348

12.5863

1.2708

0.00223

0.01696

1.1768

PC(20:4(5Z,8Z,11Z,14Z)/15:0)

0.9031

14.104

2.4255

0.000332

0.005473

1.8701

SM(d18:0/16:1(9Z))

-0.9505

13.0766

19.0271

3.86E-05

0.001593

0.5174

Sphingosine 1-phosphate

-0.5039

10.3455

1.0297

4.92E-06

0.000451

0.7052

Taurine

-1.0405

0.68757

1.1709

5.74E-07

0.000128

0.4862

Ursocholic acid

-2.2665

9.5403

1.0286

0.01302

0.05564

0.2078

N2-gamma-Glutamylglutamine

-1.4247

0.6876

1.5007

3.49E-06

0.000364

0.3725

L-Norleucine

0.23482

1.3388

3.6752

0.04904

0.137118

1.1768

Propionylcarnitine

1.2261

1.3976

2.3843

0.000976

0.010334

2.3394

2-Tetradecanone

0.3418

8.8515

1.4916

0.00018

0.00387

1.2671

Tryptophyl-Phenylalanine

-1.4872

5.4163

1.0591

2.42E-07

7.86E-05

0.3567