Table 5 Association according to the recessive model (AA with TA + TT as reference) between the rs2043211 polymorphism in the CARD8 gene encoding C10X truncated variant and expression of 15 proteins studied by Olink proteomics

ADA

-0.041

0.632

-0.042

0.636

0.056

0.456

0.040

0.612

0.049

0.740

0.010

0.951

AXL

0.157

0.027

0.124

0.081

-0.071

0.216

-0.066

0.251

-0.201

0.127

-0.149

0.252

CCL20

-0.166

0.333

-0.205

0.234

0.170

0.227

0.122

0.407

-0.063

0.823

-0.098

0.740

CD40

-0.160

0.058

-0.134

0.112

-0.009

0.917

-0.052

0.535

0.024

0.882

0.014

0.938

CXCL1

-0.195

0.201

-0.151

0.326

0.149

0.213

0.121

0.333

0.387

0.108

0.344

0.162

CXCL6

-0.101

0.519

-0.094

0.544

0.187

0.207

0.131

0.392

-0.010

0.977

-0.092

0.802

IL-6

-0.133

0.283

-0.153

0.213

0.229

0.058

0.163

0.157

0.346

0.172

0.364

0.130

IL-8

-0.039

0.707

-0.047

0.655

0.096

0.279

0.080

0.370

-0.099

0.636

-0.139

0.535

IL-18R1

0.032

0.689

-0.005

0.953

0.149

0.037

0.093

0.186

0.018

0.899

0.015

0.913

MCP-1

0.154

0.016

0.147

0.023

0.033

0.580

0.029

0.631

-0.058

0.656

-0.044

0.749

OPG

0.071

0.207

0.067

0.251

0.037

0.508

0.024

0.673

-0.018

0.897

-0.092

0.506

t-PA

0.243

0.299

0.206

0.375

0.150

0.513

-0.070

0.759

-0.023

0.956

-0.242

0.550

TWEAK

-0.042

0.489

-0.045

0.478

0.006

0.923

-0.003

0.958

0.108

0.493

0.023

0.889

VEGF-A

-0.047

0.499

-0.063

0.355

0.005

0.942

-0.031

0.656

0.036

0.794

0.056

0.700

4E-BP1

-0.127

0.353

-0.152

0.263

0.107

0.401

0.060

0.652

0.314

0.238

0.227

0.422