Table 2 Basic characteristics of the Lifestyle, Biomarkers and Atherosclerosis (LBA) cohort based on genotypes in the rs2043211 polymorphism in the CARD8 gene
Total | TT | TA | AA | |
|---|---|---|---|---|
Men ( n = 233) a | ||||
Age (years) | 22.0 (2.0) | 21.9 (2.0) | 22.0 (2.1) | 22.8 (1.6) |
Height (cm) | 181.7 (6.7) | 181.6 (6.3) | 181.5 (7.1) | 182.4 (7.0) |
Weight (kg) | 77.7 (11.5) | 77.0 (10.7) | 78.1 (12.8) | 79.2 (9.0) |
BMI (kg/m2) | 23.5 (3.1) | 23.3 (3.0) | 23.7 (3.4) | 23.8 (2.4) |
LDL (mmol/L) | 2.3 (0.7) | 2.2 (0.6) | 2.4 (0.8) | 2.5 (0.6) |
Triglycerides (mmol/L) | 0.8 (0.4) | 0.8 (0.3) | 0.8 (0.4) | 0.9 (0.3) |
Systolic blood pressure (mm Hg) | 124.9 (11.9) | 123.9 (12.5) | 126.2 (11.9) | 123.5 (9.5) |
Insulin (mU/L) | 6.8 (4.9, 9.1) | 6.8 (5.0, 9.4) | 7.0 (4.9, 9.1) | 6.7 (4.3, 8.8) |
CRP (mg/L) | 0.5 (0.3, 1.1) | 0.4 (0.3, 1.0) | 0.6 (0.2, 1.5) | 0.6 (0.2, 1.0) |
Non-estrogen using women ( n = 383) a | ||||
Age (years) | 21.9 (2.0) | 22.1 (1.9) | 21.7 (2.0) | 21.8 (2.0) |
Height (cm) | 168.6 (6.6) | 168.3 (6.1) | 168.9 (7.1) | 168.8 (6.3) |
Weight (kg) | 63.7 (11.1) | 64.2 (10.5) | 63.1 (11.8) | 63.9 (11.0) |
BMI (kg/m2) | 22.4 (3.5) | 22.6 (3.4) | 22.1 (3.5) | 22.4 (3.7) |
LDL (mmol/L) | 2.2 (0.6) | 2.2 (0.7) | 2.2 (0.6) | 2.2 (0.6) |
Triglycerides (mmol/L) | 0.7 (0.3) | 0.7 (0.3) | 0.7 (0.3) | 0.9 (0.5) |
Systolic blood pressure (mm Hg) | 109.8 (8.8) | 110.3 (9.1) | 109.2 (8.2) | 110.5 (10.1) |
Insulin (mU/L) | 7.0 (5.1, 9.8) | 7.0 (5.1, 9.7) | 6.8 (5.1, 9.6) | 8.4 (6.7, 10.5) |
CRP (mg/L) | 0.6 (0.3, 1.1) | 0.5 (0.3, 1.1) | 0.5 (0.3, 1.0) | 0.7 (0.4, 1.1) |
Estrogen-using women ( n = 128) a | ||||
Age (years) | 21.7 (1.8) | 21.7 (1.8) | 21.8 (1.9) | 21.6 (1.4) |
Height (cm) | 168.6 (5.8) | 168.0 (6.2) | 169.5 (5.3) | 168.0 (5.6) |
Weight (kg) | 63.2 (10.6) | 62.3 (8.5) | 64.8 (13.3) | 60.3 (5.5) |
BMI (kg/m2) | 22.2 (3.1) | 22.0 (2.5) | 22.5 (3.9) | 21.4 (1.8) |
LDL (mmol/L) | 2.6 (0.8) | 2.6 (0.9) | 2.5 (0.7) | 3.1 (0.9) |
Triglycerides (mmol/L) | 1.0 (0.4) | 1.0 (0.4) | 1.0 (0.4) | 1.0 (0.6) |
Systolic blood pressure (mm Hg) | 112.8 (8.9) | 112.1 (8.6) | 114.2 (9.1) | 109.6 (9.8) |
Insulin (mU/L) | 7.1 (4.9, 10.1) | 6.8 (4.4, 10.1) | 7.0 (5.6, 9.9) | 9.0 (7.5, 10.3) |
CRP (mg/L) | 1.6 (0.7, 3.1) | 1.9 (0.9, 3.1) | 1.0 (0.6, 3.0) | 2.3 (0.5, 3.9) |