Variable | Overall (n = 332) | Group 1 (n = 148) | Group 2 (n = 111) | Group 3 (n = 73) | P value |
---|---|---|---|---|---|
Demographics | |||||
Age, years | 62.9 ± 12.3 | 56.2 ± 10.4 | 65.6 ± 11.1* | 72.1 ± 10.1*§ | < 0.001 |
Male, n (%) | 253 (76.2) | 131 (88.5) | 84 (75.7) * | 38 (52.1) *§ | < 0.001 |
BMI, kg/m2 | 24.9 ± 3.3 | 25.4 ± 2.8 | 24.9 ± 3.3 | 24.0 ± 3.9* | 0.009 |
Risk factors, n (%) | |||||
Hypertension | 198 (59.6) | 74 (50.0) | 74 (66.7) * | 50 (68.5) * | 0.006 |
Dyslipidemia | 174 (52.6) | 78 (52.7) | 62 (56.4) | 34 (46.6) | 0.43 |
Diabetes mellitus | 107 (32.3) | 37 (25.0) | 36 (32.4) * | 34 (46.6) * | 0.006 |
Current smokers | 203 (61.1) | 109 (73.7) | 64 (57.7) * | 30 (41.1) * | < 0.001 |
Family history of premature CHD | 56 (16.9) | 32 (21.6) | 18 (16.4) * | 6 (8.2) * | 0.032 |
Previous MI | 16 (4.8) | 9 (6.1) | 4 (3.6) | 3 (4.1) | 0.63 |
Previous PCI | 34 (10.3) | 17 (11.5) | 11 (10.0) | 6 (8.2) | 0.74 |
Killip classification, n (%) | 0.073 | ||||
I | 243 (73.9) | 117 (80.1) | 81 (73.6) | 45 (61.6) | |
II | 62 (18.8) | 22 (15.1) | 19 (17.3) | 21 (28.8) | |
III | 11 (3.3) | 4 (2.7) | 3 (2.7) | 4 (5.5) | |
VI | 13 (4.0) | 3 (2.1) | 7 (6.4) | 3 (4.1) | |
GRACE risk score | 156.9 ± 32.0 | 143.7 ± 25.8 | 108.9 ± 33.4* | 174.0 ± 30.3*§ | < 0.001 |
Lab results | |||||
TC, mmol/L | 4.2 ± 1.1 | 4.3 ± 1.2 | 4.3 ± 1.0 | 4.2 ± 1.0 | 0.94 |
TG, mmol/L | 1.7 ± 1.4 | 1.8 ± 1.5 | 1.7 ± 1.3 | 1.5 ± 1.1 | 0.18 |
LDL-c, mmol/L | 2.7 ± 0.9 | 2.7 ± 0.9 | 2.7 ± 0.8 | 2.7 ± 0.9 | 0.98 |
HDL-c, mmol/L | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.2 | 0.13 |
FBG, mmol/L | 7.5 ± 3.8 | 7.3 ± 4.5 | 7.8 ± 3.5 | 7.8 ± 2.8 | 0.56 |
HbA1c, % | 7.1 ± 1.7 | 7.4 ± 1.8 | 6.6 ± 1.3 | 7.1 ± 2.0 | 0.18 |
Uric acid, mmol/L | 332.3 ± 97.8 | 341.3 ± 98.1 | 327.4 ± 100.8 | 321.3 ± 92.2 | 0.29 |
Serum creatinine, µmol/L | 72.0 (63.0, 84.0) | 72.0 (63.3, 82.8) | 73.0 (64.0, 87.5) | 71.0 (55.5, 84.5) | 0.26 |
BNP, pg/mL | 205.3 (88.2, 393.8) | 161.0 (72.6, 236.6) | 138.8 (81.7, 693.5) | 375.2 (232.9, 563.3) * | 0.008 |
Echocardiographic data | |||||
LVEDD, mm | 47.7 ± 5.2 | 48.4 ± 5.3 | 47.2 ± 5.2 | 46.9 ± 4.8 | 0.069 |
LAD, mm | 36.3 ± 4.3 | 36.1 ± 4.0 | 36.4 ± 4.8 | 36.7 ± 3.9 | 0.6 |
LVEF, % | 50.1 ± 12.2 | 50.9 ± 1.0 | 49.4 ± 1.2 | 49.5 ± 1.4 | 0.55 |
Vascular and valvular calcifications | |||||
Coronary artery calcification, n (%) | |||||
Left anterior descending branch | 170 (51.2) | 18 (12.2) | 79 (71.2) * | 73 (100) *§ | < 0.001 |
Left circumflex artery | 84 (25.3) | 0 (0) | 20 (18.0) * | 64 (87.7) *§ | < 0.001 |
Right coronary artery | 105 (31.6) | 6 (4.0) | 33 (29.7) * | 66 (90.4) *§ | < 0.001 |
Thoracic aorta calcification, n (%) | 135 (40.7) | 18 (12.2) | 63 (56.8) * | 54 (74.0) * | < 0.001 |
Aortic valve calcification, n (%) | 191 (57.5) | 43 (29.0) | 81 (73.0) * | 67 (91.8) *§ | < 0.001 |
Calcification score | 2.0 ± 1.6 | 0.6 ± 0.5 | 2.5 ± 0.5* | 4.4 ± 0.5*§ | < 0.001 |