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Table 3 Primary and secondary endpoints for the sacubitril valsartan and control groups

From: Effect of sacubitril valsartan on heart failure with mid-range or preserved ejection fraction in patients on maintenance hemodialysis: real-world experience in a single-center, prospective study

Outcome

SV

(n = 59)

Control

(n = 59)

P

Primary Composite Endpoints

   

Total number of hospitalizations for HF and death from cardiovascular causes

19

24

0.1

Total number of hospitalizations for HF

17

20

0.5

Death from cardiovascular causes, number (%)

2 (3.39)

4 (6.78)

0.3

Secondary endpoints

   

Changes in ADQI HF class from baseline to 12 months, number (%)

  

Pearson X2 = 24.191

P < 0.001

 Improved

39 (66.10)

15 (25.42)

--

 Unchanged

19 (32.21)

33 (55.93)

--

 Worsened

1 (1.69)

11 (18.64)

--

Death from all causes, number (%)

3 (5.08)

4 (6.78)

0.5

  1. Values are expressed as n or n (%), unless indicated otherwise
  2. Abbreviations: SV, sacubitril valsartan; HF, heart failure; ADQI, The Acute Dialysis Quality Initiative Workgroup