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Table 2 Univariable logistic analysis of the risk factors for postoperative cardiovascular complications

From: Association between postoperative nadir platelet count and postoperative cardiovascular complications following septal myectomy in patients with hypertrophic cardiomyopathy: a retrospective cohort study

Variable

Odds ratio (95% confidence interval)

P

Age (years)

1.01 (0.97–1.04)

0.756

Female

1.19 (0.47–3.03)

0.716

Body mass index (kg/m2)

0.97 (0.86–1.1)

0.635

Family history of HCM

2.5 (0.75–8.36)

0.137

Family history of sudden death

1.78 (0.42–7.49)

0.433

History of syncope

0.74 (0.26–2.08)

0.571

Duration of clinical symptoms (years)

0.99 (0.91–1.07)

0.757

Comorbidities

  

Hypertension

1.31 (0.52–3.29)

0.562

Coronary artery disease

1.51 (0.48–4.73)

0.481

Pulmonary arterial hypertension

1.54 (0.37–6.32)

0.551

Diabetes

0 (0–Inf)

0.991

Stoke

1.32 (0.13–13.29)

0.815

Atrial fibrillation

2.76 (0.43–17.59)

0.282

Preoperative medications

  

Aspirin or Clopidogrel

1.51 (0.43–5.27)

0.517

Diuretics

4.35 (0.82–23.17)

0.085

β- blocker

0.97 (0.37–2.53)

0.945

Statin

1.98 (0.17–22.81)

0.585

ACEI or ARB

0.9 (0.27–3)

0.869

Laboratory variables

  

Baseline partial thromboplastin time (s)

0.97 (0.71–1.32)

0.833

Baseline APTT (s)

0.95 (0.86–1.04)

0.256

Baseline INR

0.85 (0.25–2.89)

0.799

Baseline hemoglobin (g/L)

1.01 (0.99–1.04)

0.258

Baseline platelet count (109/L)

1 (0.99–1.01)

0.835

Preoperative echocardiography

  

Left atrium dimension (mm)

1.01 (0.94–1.09)

0.694

Ejection fraction (%)

0.98 (0.91–1.05)

0.549

Maximal septal thickness (mm)

0.99 (0.91–1.07)

0.720

Resting LVOT gradient (mm Hg)

1 (0.99–1.01)

0.870

With systolic anterior motion

1.03 (0.31–3.43)

0.965

Intraoperative parameters

  

Anesthesia time (min)

1 (1–1.01)

0.125

Surgical time (min)

1.01 (1–1.01)

0.105

Cardiopulmonary bypass time (min)

1.01 (1–1.01)

0.122

Cross-clamp time (min)

1 (0.99–1.02)

0.833

Concomitant other procedure

1.18 (0.45–3.11)

0.736

Hypotension time (min)

1.01 (1–1.01)

0.024

Intraoperative fluid management

  

Fluid intake (mL)

1 (1–1)

0.407

Red blood cells (units)

0.9 (0.70–1.16)

0.417

Plasma (mL)

1 (1–1)

0.420

Total output (mL)

1 (1–1)

0.460

Blood loss (mL)

1 (1–1)

0.795

Urine volume (mL)

1 (1–1)

0.609

Blood products within the first 4 days postoperatively

  

Red blood cells (units)

1.4 (1.15–1.71)

0.001

Plasma (mL)

1 (1–1)

< 0.001

Cryoprecipitate

2.16 (0.59–7.92)

0.246

Platelet

6.6 (1.03–42.14)

0.046

Blood loss within first 4 days postoperatively (mL)

1 (1–1)

0.019

  1. Abbreviations: OR odds ratio, CI confidence interval, HCM hypertrophic cardiomyopathy, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, APTT activated partial thromboplastin time, INR international normalized ratio, LVOT left ventricular outflow tract