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Table 1 The baseline characteristics of elderly patients with AMI.

From: The association between serum uric acid / serum creatinine ratio and in-hospital outcomes in elderly patients with acute myocardial infarction

Variable

Overall

(n = 330)

MACEs

(n = 68)

Non-MACEs

(n = 262)

P-Value

Death

(n = 44)

Survival

(n = 286)

P-Value

Age (years)

80.0 (77.0, 83.0)

81.0 (78.0, 84.0)

80.0 (77.0, 83.0)

0.193

81.0 (79.0, 83.0)

80.0 (77.0, 83.0)

0.162

 ≥ 80 (n, %)

180 (54.5)

40 (58.9)

140 (54.2)

0.427

28 (63.6)

152 (53.1)

0.193

Male (n, %)

217 (65.8)

47 (69.2)

170 (64.8)

0.512

30 (68.2)

187 (65.4)

0.716

Medical history (n, %)

       

 Hypertension

223 (67.6)

48 (70.6)

175 (66.8)

0.551

31 (70.5)

192 (67.1)

0.661

 Diabetes

100 (30.3)

25 (36.8)

75 (28.6)

0.193

15 (34.1)

85 (29.7)

0.557

 Prior MI

46 (13.9)

11 (16.2)

35 (13.4)

0.550

8 (18.2)

38 (13.3)

0.383

 Prior PCI or CABG

49 (14.8)

10 (14.7)

39 (14.9)

0.970

6 (13.6)

43 (15.0)

0.808

 Prior stroke

45 (13.6)

8 (11.8)

37 (14.1)

0.614

3 (6.8)

42 (14.7)

0.157

Medication history (n, %)

       

 Diuretics

57 (17.2)

21 (30.9)

36 (13.7)

0.001*

17 (38.6)

40 (14.0)

< 0.001*

 Dapagliflozin

11 (3.3)

1 (1.5)

10 (3.8)

0.561

0 (0)

11 (3.8)

0.371

 Allopurinol

5 (1.5)

2 (2.9)

3 (1.1)

0.601

2 (4.5)

3 (1.0)

0.269

 Febuxostat

4 (1.2)

1 (1.5)

3 (1.1)

1.000

0 (0)

4 (1.4)

1.000

 ARB

70 (21.2)

21 (30.9)

49 (18.7)

0.029*

13 (29.5)

57 (19.9)

0.146

Cardiac arrest before admission

23 (7.0)

5 (7.4)

18 (6.9)

0.889

4 (9.1)

19 (6.6)

0.553

Current smoking

59 (17.9)

10 (14.7)

49 (18.7)

0.443

5 (11.4)

54 (18.9)

0.226

Clinical characteristics (n, %)

       

 STEMI

235 (71.2)

51 (75.0)

184 (70.2)

0.439

32 (72.7)

203 (71.0)

0.812

 TIMI risk score

4.0 (3.0, 6.0)

5.0 (4.0, 7.8)

4.0 (3.0, 5.0)

< 0.001*

5.5 (4.0, 8.0)

4.0 (3.0, 5.0)

< 0.001*

Revascularization details (n, %)

       

 Multi-vessel disease

238 (72.1)

49 (72.1)

189 (72.1)

0.990

31 (70.5)

207 (72.4)

0.791

 Symptom-onset-to-balloon time within 12 h

170 (51.5)

27 (39.7)

143 (54.6)

0.029*

16 (36.4)

154 (53.8)

0.031*

 PCI or not

291 (88.2)

52 (76.5)

239 (91.2)

0.001*

33 (75.0)

258 (90.2)

0.004*

 Complete revascularization

208 (63.0)

39 (57.4)

169 (64.5)

0.276

25 (56.8)

183 (64.0)

0.359

Medication during hospitalization (n, %)

       

 Diuretics

186 (55.8)

49 (72.1)

137 (52.3)

0.002*

33 (75.0)

153 (53.5)

0.006*

 Dapagliflozin

3 (0.9)

1 (1.5)

2 (7.6)

1.000

1 (2.3)

2 (0.7)

0.865

 Allopurinol

1 (0.3)

0 (0)

1 (3.8)

1.000

0 (0)

1 (0.3)

1.000

 Febuxostat

1 (0.3)

1 (1.5)

0 (0)

0.467

0 (0)

1 (0.3)

1.000

 ARB

40 (12.1)

12 (17.6)

28 (10.7)

< 0.001*

8 (18.2)

32 (11.2)

0.186

 Dual anti-platelet therapy

330 (100)

68 (100)

262 (100)

1.000

44 (100)

286 (100)

1.000

 Statins

328 (99.4)

67 (98.5)

261 (99.6)

0.212

43 (97.7)

285 (99.7)

0.626

Biochemical variables

       

 Peak CK-MB

138.5

(60.4, 276.4)

172.5

(61.7, 307.7)

134.0

(59.9, 270.1)

0.229

200.3

(77.3, 341.7)

132.6

(58.6, 270.0)

0.063

 Hemoglobin (g/L)

127.0

(113.0, 137.0)

122.0

(104.3, 136.8)

127.5

(115.0, 138.0)

0.117

124.0

(103.3, 135.9)

127.0

(114.4, 138.0)

0.305

 Total bilirubin (mmol/L)

14.9 (10.8, 19.8)

17.6 (12.0,21.9)

14.7 (10.7, 18.6)

0.068

17.9 (12.2, 21.9)

14.8 (10.7,19.2)

0.077

 Total cholesterol (mmol/L)

4.5 (3.8, 5.2)

4.2 (3.7, 5.1)

4.5 (3.9, 5.2)

0.112

4.2 (3.6, 5.2)

4.5 (3.9, 5.2)

0.076

 HDL-c (mmol/L)

1.0 (0.9, 1.2)

1.0 (0.9, 1.3)

1.0 (0.9, 1.2)

0.907

1.1 (0.9, 1.3)

1.0 (0.9, 1.2)

0.223

 LDL-c (mmol/L)

2.8 (2.3, 3.4)

2.6 (2.1, 3.1)

2.9 (2.4, 3.5)

0.008*

2.5 (2.0, 2.9)

2.9 (2.4, 3.5)

0.005*

 Uric acid (µmol/L)

419.1

(342.8, 515.1)

419.1

(360.5, 555.8)

419.5

(341.8, 504.9)

0.337

414.1

(377.1, 551.0)

419.1

(341.5, 512.0)

0.307

 Creatinine (µmol/L)

98.0

(78.0, 126.9)

122.3

(98.1, 147.8)

92.6

(75.8, 121.0)

< 0.001*

125.9

(98.5, 149.5)

94.0

(76.1, 123.0)

< 0.001*

 SUA/Scr

4.2 (3.0, 5.8)

3.5 (2.6, 4.8)

4.5 (3.2, 5.9)

0.001*

3.4 (2.6, 4.9)

4.4 (3.1, 5.9)

0.016*

 NT-pro BNP (pg/ml)

4202.5

(1680.5, 8605.0)

4455.5

(2905.5, 9025.3)

4069.0

(1468.3, 8443.5)

0.078

4175.5

(2820.3, 8618.8)

4200.0

(1535.0, 8595.0)

0.327

LVEF (%)

47.0 (38.0, 58.0)

38.0 (33.0, 47.8)

49.0 (40.0, 59.3)

< 0.001*

37.5 (32.0, 46.0)

48.0 (40.0, 59.0)

< 0.001*

  1. ARB, angiotensin receptor antagonist; STEMI, ST-segment elevation MI; PCI, percutaneous coronary intervention; CK-MB, creatine kinase myocardial band; HDL-c, high density lipoprotein cholesterol; LDL-c, low density lipoprotein cholesterol; SUA/Scr, serum uric acid/ serum creatinine; NT-pro BNP, N-terminal pro-brain natriuretic peptide; LVEF, left ventricular ejection fraction. * P < 0.05