Table 1 Inclusion and exclusion criteria

Inclusion criteria

 1. Patients with an indication for PCI due to acute coronary syndrome (including STEMI, NSTEMI, and unstable angina)

 2. All intended target lesion(s) are successfully treated by PCI with only drug-coated balloon(s)

 3. Patients who are able to complete the follow-up and compliant to the prescribed medication

Exclusion criteria

 1. Under the age of 18 or older than 80 years old

 2. Unable to give informed consent

 3. Patient is a woman who is pregnant or nursing

 4. Known contraindications to medications such as heparin, antiplatelet drugs, or contrast

 5. Currently participating in another trial and not yet at its primary endpoint

 6. Planned elective surgery

 7. Concurrent medical condition with a life expectancy of less than 1 years

 8. Previous intracranial hemorrhage

 9. Required long-term oral anticoagulant therapy

 10. Cardiogenic shock

 11. Previous stent implantation within 6 months

 12. In-stent thrombosis

 13. Target lesion located in surgical conduit