Fig. 5

Colchicine inhibits pyroptosis through the AMPK / SIRT1 / NLRP3 signaling pathway. (A-B) The changes of protein expression levels in p-AMPK, AMPK, and SIRT1 for each group (n = 4). The blots in Fig. 5A were from different gels. The original western blot images were provided in the supplementary file. (C) The immunofluorescence images of SIRT1 in rat myocardial tissue for each group (n = 4). ^*p<0.05 versus Sham group; ^&p<0.05 versus CME group; ^#p<0.05 versus CME + COL group