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Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: Colchicine ameliorates myocardial injury induced by coronary microembolization through suppressing pyroptosis via the AMPK/SIRT1/NLRP3 signaling pathway

Fig. 3

Colchicine ameliorates myocardial pyroptosis induced by CME. (A) The changes of mRNA expression levels in NLRP3, ASC, and IL-1β for each group (n = 5). (B) The changes of protein expression levels in NLRP3, GSDMD-N, ASC, IL-18, IL-1β, and caspase 1 p20 for each group. n = 4 for each group. The blots in Fig. 3B were from different gels. The original western blot images were provided in the supplementary file. *p<0.05 versus Sham group; &p<0.05 versus CME group; #p<0.05 versus CME + COL group

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