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Table 2 In-hospital outcomes of patients undergoing TAVR in the United States from 2016 to 2020

From: In-hospital outcomes of transcatheter aortic valve replacement in patients with chronic and end-stage renal disease: a nationwide database study

 

All patients n = 279,195

Normal renal function

n = 187,325

CKD

n = 81,640

ESRD

n = 10,230

CKD

ESRD

aOR (95%CI)

p value

aOR

(95% CI)

p value

 

In-hospital mortality

3710 (1.3%)

2145 (1.1%)

1295 (1.6%)

270 (2.6%)

1.4 (1.2–1.7)

< 0.001

2.4 (1.8–3.3)

< 0.001

 

LOS, days (SEM)

3.8 (0.04)

3.3 (0.03)

4.6 (0.06)

6.9 (0.22)

N/A

< 0.001

N/A

< 0.001

 

Cardiovascular complications

 

Cardiac arrest

620 (0.2)

340 (0.2)

230 (0.3)

50 (0.5)

1.5 (1.0-2.1)

0.058

2.4 (1.2–4.9)

0.015

 

Cardiogenic shock

4010 (1.4)

2415 (1.3)

1305 (1.6)

290 (2.8)

1.2 (1.1–1.4)

0.009

2.0 (1.5–2.7)

< 0.001

 

Impella

880 (0.3)

450 (0.2)

355 (0.4)

75 (0.7)

1.8 (1.3–2.5)

< 0.001

1.9 (1.0-3.4)

0.035

 

Intraaortic balloon

1195 (0.4)

675 (0.4)

385 (0.5)

135 (1.3)

1.3 (0.9–1.7)

0.126

2.1 (1.3–3.3)

0.002

 

Procedural AMI

8655 (3.1)

5445 (2.9)

2645 (3.2)

565 (5.5)

1.1 (0.9–1.2)

0.329

1.7 (1.4–2.1)

< 0.001

 

Vascular access complications

10,235 (3.7)

6465 (3.5)

3300 (4.0)

470 (4.6)

1.2 (1.1–1.3)

0.003

1.3 (1.0-1.6)

0.043

 

Conversion to open heart surgery

960 (0.3)

675 (0.4)

240 (0.3)

45 (0.4)

0.9 (0.6–1.2)

0.384

1.3 (0.6–2.6)

0.479

 

Other complications

 

Post-operative infection

2350 (0.8)

1175 (0.6)

885 (1.1)

290 (2.8)

1.8 (1.5–2.2)

< 0.001

3.0 (2.2–4.1)

< 0.001

 

Respiratory complications

18,905 (6.8)

10,355 (5.5)

7010 (8.6)

1540 (15.1)

1.5 (1.4–1.6)

< 0.001

2.3 (2.0-2.6)

< 0.001

 

AKI

26,770 (9.6)

9340 (5.0)

17,340 (21.2)

N/A

5.0 (4.7–5.3)

< 0.001

N/A

N/A

 
  1. Abbreviations: AKI acute kidney injury, AMI acute myocardial infarction, aOR adjusted odds ratio, CI confidence interval, CKD chronic kidney disease, ESRD end stage renal disease, LOS length of stay, TAVR transcatheter aortic valve replacement, SEM standard error of the mean.