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Table 1 Comparison of clinical and laboratory parameters between the non-HF group and HF group

From: Association of serum Asprosin concentrations with heart failure

Variables

non-HF (N = 103)

HF (N = 103)

P

Gender (M/F)

49/54

64/39

0.069

Age (years)

68.17 ± 5.58

70.39 ± 10.66

0.063

BMI (kg/m2)

23.60 ± 3.52

24.35 ± 3.74

0.141

SBP (mmHg)

124.83 ± 18.17

127.83 ± 16.37

0.215

DBP (mmHg)

72.85 ± 14.35

74.8 ± 10.89

0.275

TC (mmol/L)

4.79 ± 1.00

3.69 ± 1.03*

0.000

TG (mmol/L)

1.26(0.96,1.90)

0.91(0.74,1.31)*

0.000

HDL-C (mmol/L)

1.18 ± 0.27

0.97 ± 0.25*

0.000

LDL-C (mmol/L)

2.79 ± 0.69

2.18 ± 0.74*

0.000

Apo A1 (g/L)

1.35 ± 0.20

1.08 ± 0.24*

0.000

Apo B (g/L)

0.97 ± 0.24

0.84 ± 0.34*

0.001

ALT (U/L)

14.74(11.93,22.3)

18.09(15.37,20.45)

0.717

AST (U/L)

14.81(10.23,27.00)

20.87(16.91,26.35)*

0.000

Cr (µmol/L)

66.42 ± 11.98

82.07 ± 18.17*

0.000

BUN (mmol/L)

6.58 ± 1.81

7.07 ± 2.32

0.069

FBG (mmol/L)

5.24 ± 0.98

6.24 ± 2.07*

0.000

HbA1C (%)

5.82 ± 1.36

6.57 ± 1.48*

0.000

NT-ProBNP (ng/L)

63.87(30,102.5)

1239.16(518,3535)*

0.000

IVS (mm)

8.54 ± 1.11

9.53 ± 1.58*

0.000

LVPW (mm)

8.46 ± 1.07

9.17 ± 1.1*

0.000

LAD (mm)

34.49 ± 3.87

44.48 ± 7.72*

0.000

LVEDD (mm)

45.21 ± 3.90

52.55 ± 8.63*

0.000

E/A

0.99 ± 0.34

1.15 ± 0.71

0.058

E/e′

8(7, 10)

13(11, 18)*

0.000

LVEF (%)

61.09 ± 2.51

43.5 ± 13.35*

0.000

Prevalence of DM

12(11.7%)

42(40.8%)*

0.036

Prevalence of HBP

35(34%)

83(80.6%)*

0.000

Prevalence of CAD

6(5.8%)

86(83.5%)*

0.000

Dapagliflozin

7(6.8%)

29(28.2%)*

0.000

Antiplatelet class

6(5.8%)

43(41.7%)*

0.000

Statins

28(27.2%)

82(79.6%)*

0.000

ACEI/ARB/ARNI

20(19.4%)

74(71.8%)*

0.000

β-blockers

13(12.6%)

82(79.6%)*

0.000

CCB

11(0.7%)

26(25.2%)*

0.006

Diuretics

2(1.9%)

93(90.3%)*

0.000

Nitrates

1(1%)

35(34%)*

0.000

  1. BMI: mean body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoA1: apolipoprotein A1; Apo B: apolipoprotein B; ALT: alanine aminotransferase; AST: aspartate aminotransferase; Cr: creatinine; BUN: urea nitrogen; FBG: fasting blood glucose; HbA1C: glycosylated hemoglobin; NT-proBNP: amino-terminal brain natriuretic peptide; IVS: interventricular septum; LVPW: left ventricular posterior wall; LAD: left atrial diameter; LVEDD: left ventricular end-diastolic internal diameter; LVEF: left ventricular ejection fraction; DM: diabetes; HBP: hypertension; CAD: coronary heart disease; CCB: Ca2+-blockers
  2. *For comparison with the non-HF group, P < 0.05