Association between cardiopulmonary bypass time and mortality among patients with acute respiratory distress syndrome after cardiac surgery

Table 5 Multivariable Cox regression analysis for ICU and hospital mortality grouped by CPB category

Variable	Crude		Model 1		Model 2
Variable	HR (95%CIs)	P value	HR (95%CIs)	P value	HR (95%CIs)	P value
ICU mortality
Non-CPB	1 (ref)		1 (ref)		1 (ref)
Short CPB time	3.74 (1.08–12.91)	0.037	3.38 (0.96–11.91)	0.058	15.12 (3.07–74.48)	0.001
Long CPB time	7.17 (2.17–23.69)	0.001	6.49 (1.91–20.09)	0.003	35.29 (6.66-181.71)	< 0.001
Hospital mortality
Non-CPB	1 (ref)		1 (ref)		1 (ref)
Short CPB time	1.48 (0.81–2.71)	0.203	1.27 (0.68–2.38)	0.449	3.21 (1.11–9.32)	0.032
Long CPB time	2.23 (1.25–3.98)	0.006	2.14 (1.17–3.92)	0.014	6.51 (1.97–21.47)	0.002

Short CPB time = 0 < CPB < 173 min, long CPB time = CPB 173 ≥ minutes
Model1: The results were adjusted by age, gender, BMI;
Model2: The results were adjusted by age, gender, BMI, smoking, hypertension, diabetes, cerebrovascular disease, chronic lung disease, coronary heart disease, valve disease, ACEI, β_blocker, CCB, aspirin, statins, preoperative LVEF, NYHA, operation type, aortic clamping time, operation time, blood loss, transfusion of RBCModel1: The results were adjusted by age, gender, BMI;

ISSN: 1471-2261