Table 3 Endpoint events at 12 months after covariate adjustment of Cox proportional hazards models

MACCE

17 (2.9%)

34 (5.7%)

0.540 (0.294–0.991)

0.047

 Cardiac death

5 (0.9%)

12 (2%)

0.422 (0.143–1.247)

0.118

 MI

11(1.9%)

14 (2.4%)

0.814 (0.356–1.863)

0.627

 Ischemic stroke

1 (0.2%)

8 (1.3%)

0.175 (0.021–1.462)

0.107

Bleeding(BARC2,3,5)

19(3.3%)

8(1.3%)

3.322 (1.397–7.898)

0.007

 BARC 2

15 (2.6%)

4 (0.7%)

-

0.011

 BARC 3

2 (0.3%)

4 (0.7%)

-

0.907

 BARC 5

2 (0.3%)

0

-

0.967

CAG-guided subgroup events

Ticagrelor (N = 384)

Clopidogrel (N = 390)

HR(95% CI)

p-value

MACCE

12 (3.1%)

25 (6.4%)

0.449 (0.219–0.919)

0.029

 Cardiac death

3 (0.8%)

9 (2.3%)

0.267 (0.069–1.028)

0.055

 MI

9 (2.3%)

12 (3.1%)

0.778 (0.314–1.928)

0.588

 Ishemic stroke

0

4(1%)

-

0.956

IVUS-guided subgroup events

Ticagrelor (N = 197)

Clopidogrel (N = 203)

HR(95% CI)

p-value

MACCE

5 (2.5%)

9 (4.4%)

0.811 (0.244–2.689)

0.732

 Cardiac death

2 (1%)

3 (1.5%)

0.801 (0.082–7.850)

0.849

 MI

2 (1%)

2 (1%)

1.028 (0.123–8.567)

0.980

 Ischemic stroke

1 (0.5%)

4 (2%)

0.536 (0.050–5.804)

0.608