Table 4 Characteristics of the study sample, categorized by rSS tertiles

Variable

1st rSS Tertile (≤4)

(n = 51)

2nd rSS Tertile (4 – 12)

(n = 55)

3rd rSS Tertile (> 12)

(n = 43)

P value

Age^a

55.41 (±11.17)

58 (47 – 64)

60.62 (±10.34)

61 (55 – 66)

65.07 (±12.25)

64 (55 – 71)

0.002*

Sex^b

Male: 38 (74.5%)

Male: 36 (65.5%)

Male: 28 (65.1%)

0.5

BMI^b

28.18 (±4.85)

27.7 (24.43 – 30.75)

28 (±3.86)

27.7 (25.7 – 29.4)

27.2 (±4.69)

26.7 (23.4 – 29.4)

0.6

Dyslipidemia^$

25 (49%)

33 (60%)

25 (58.1%)

0.5

Smoking^c

26 (51%)

25 (45.5%)

16 (37.2%)

0.5

Hypertension^c

22 (43.1%)

25 (45.5%)

20 (46.5%)

0.9

Diabetes^c

20 (39.2%)

20 (36.4%)

12 (27.9%)

0.5

Pain to Presentation Time (Hours) ^b

7.12 (± 5.71)

6 (3.5 – 10)

7.32 (± 6.68)

6 (2 – 10)

6.56 (± 5.77)

5 (3 – 8)

0.8

STEMI/NSTEMI^c

35 (68.6%)/16 (31.4%)

43 (78.2%)/12 (21.8%)

39 (90.7%)/4 (9.3%)

0.034*

KILLIP Classification^c

Class I: 45 (88.2%)

Class II: 3 (5.9%)

Class III: 1 (2%)

Class IV: 2 (3.9%)

Class I: 42 (76.4%)

Class II: 11 (20%)

Class III: 1 (1.8%)

Class IV: 1 (1.8%)

Class I: 38 (88.4%)

Class II: 1 (2.3%)

Class IV: 4 (9.3%)

0.024*

ST Resolution^c

(n = 117)

N/A: 2 (5.7%)

< 30%: 1 (2.9%)

30-70%: 23 (65.7%)

> 70%: 9 (25.7%)

(n = 35)

< 30%: 7 (16.3%)

30-70%: 22 (51.2%)

> 70%: 14 (32.6%)

(n = 43)

N/A: 5 (12.8%)

< 30%: 2 (5.1%)

30-70%: 25 (64.1%)

> 70%: 7 (17.9%)

(n = 39)

0.037*

Significant ST Resolution^c (n = 117)

39 (90.7%)

37 (84.1%)

24 (80%)

0.4

Ejection Fraction %^a

52.47 (± 10.31)

53 (44 – 60)

52.64 (± 10.64)

54 (44 – 63)

50.13 (± 11.95)

50 (41 – 62)

0.5

Myocardial Wall Motion Score Index^b

1.43 (± 0.37)

1.63 (1.13 – 1.63)

1.39 (± 0.29)

1.375 (1.12 – 1.63)

1.463 (± 0.57)

1.38 (1.25 – 1.69)

0.7

In-Hospital GRACE Score^b

137.45 (± 22.42)

136 (123 – 154)

151.82 (± 27.81)

148 (133 – 168)

161.79 (± 35.44)

156 (139 – 177)

0.001*

Post-Discharge GRACE Score^b

105.14 (± 21.19)

106 (90.5 – 121.5)

120.15 (± 22.72)

119 (103 - 131)

126.67 (± 27.78)

123 (105 – 151)

< 0.001*

Total CK on Admission^b

1395 (± 1930.71)

559 (148 – 1866)

1344.89 (± 1673.4)

548 (203 – 1717)

1419.44 (± 1887.02)

964 (359.25 – 1816.5)

0.4

Peak CK value^b

1768.09 (± 2070.53)

879 (258 – 2446)

1797.66 (± 2066.65)

1079 (330 – 1986)

1835.5 (± 1898.92)

1252.5 (619 – 2783)

0.4

CK-MB on Admission^b

168.75 (± 203.47)

80.50 (36.25 – 241.75)

143.18 (± 150.74)

71.5 (38 – 199.75)

256.46 (± 411.99)

135 (46 – 269)

0.2

Peak CK-MB value^b

195.58 (± 204.91)

116.50 (53.25 – 286.25)

182.18 (± 186.42)

112 (52 – 247.75)

301.89 (± 407.24)

193 (93 – 325)

0.4

Troponin^b

7.55 (± 12.77)

1.59 (0.35 – 10.8)

14.57 (± 31.04)

2.9 (0.66 – 12.83)

22.001 (± 25.2)

7.11 (2.35 – 50)

0.2

S. Urea on Admission^b

5.8 (± 2.9)

5 (4 – 7)

6.289 (± 2.75)

6 (4.5 – 7)

6.3 (± 3.1)

6 (5 – 7)

0.3

S. Creatinine on Admission^b

0.88 (± 0.26)

0.9 (0.7 – 1)

0.9369 (±0.28)

0.9 (0.8 – 1.1)

1.119 (± 0.76)

1 (0.7 – 1.3)

0.1

Creatinine Clearance^a

105.67 (± 28.43)

100 (84 – 128)

100.24 (± 31.23)

104 (75.5 – 122.75)

81.03 (± 36.7)

84 (47 – 110.5)

0.018*

Dominance^c

Right: 47 (92.2%)

Left: 4 (7.8%)

Right: 48 (87.3%)

Left: 7 (12.7%)

Right: 41 (95.3%)

Left: 2 (4.7%)

0.4

Number of Initial Lesions^b

2.27 (± 0.49)

3.22 (± 1.12)

3.91 (± 1.62)

< 0.001*

Number of Residual Lesions^b

0.55 (± 0.54)

2.05 (± 0.91)

3.19 (± 1.62)

< 0.001*

Culprit Vessel^c

RCA: 10 (19.6%)

LMCA: 1 (2%)

LAD: 32 (62.7%)

LCx: 8 (15.7%)

RCA: 18 (32.7%)

LM: 0 (0%)

LAD: 28 (50.9%)

LCx: 9 (16.4%)

RCA: 24 (55.8%)

LM: 1 (2.3%)

LAD: 12 (27.9%)

LCx: 6 (14%)

0.009*

Baseline Culprit TIMI Flow^c

0-1: 26 (51%)

2-3: 25 (49%)

0-1: 37 (67.3%)

2-3: 18 (32.7%)

0-1: 32 (74.4%)

2-3: 11 (25.6%)

0.049*

Post-procedural Culprit TIMI Flow^c

0-1: 0 (0%)

2-3: 51 (100%)

0-1: 0 (0%)

2-3: 55 (100%)

0-1: 4 (9.3%)

2-3: 39 (90.7%)

0.007*

Cases with LMCA Lesions^c

1 (2%)

0 (0%)

8 (18.6%)

< 0.001*

Proximal RCA^c

13 (25.5%)

19 (34.5%)

23 (53.5%)

0.018*

Proximal LAD^c

22 (43.1%)

21 (38.2%)

26 (60.5%)

0.08

Proximal LCx^c

11 (21.6%)

19 (34.5%)

27 (62.8%)

< 0.001*

Staged PCI^c

15 (29.4%)

12 (21.8%)

3 (7%)

0.024*

Interval Between PCI Sessions in Months^b

4.3 (± 3.3)

3 (3 – 5)

6.25 (± 3.72)

6 (3 – 10)

3.33 (± 0.58)

3 (N/A)

0.3

bSS^b

17.333 (± 6.07)

18 (12 – 22)

22.191 (± 7.19)

22 (16 – 27)

32.884 (± 11.96)

29.5 (24.5 – 39)

< 0.001*

SRI %^b

91.34% (± 10.67)

94.44% (84.62 – 100)

57.429% (± 18.96)

59.09% (50 – 71.43)

28.93% (± 16.7)

29.73 (16.87 – 43.48)

< 0.001*

Number of Stents Used^b

2.02 (± 0.91)

2.02 (± 1.03)

1.42 (± 0.82)

0.021*

In-Hospital Composite MACE^c

4 (7.8%)

10 (18.2%)

8 (18.6%)

0.2

In-Hospital Heart Failure^c

1 (2%)

10 (18.2%)

2 (4.7%)

0.005*

In-Hospital Re-Infarction^c

0 (0%)

0 (0%)

1 (2.3%)

0.3

In-Hospital TLR^c

0 (0%)

0 (0%)

1 (2.3%)

0.3

In-Hospital Death^c

2 (3.9%)

0 (0%)

5 (11.6%)

0.024*

In-Hospital Bleeding^c

1 (2%)

0 (0%)

0 (0%)

0.6

Acute Kidney Injury^c

3 (6.1%)

5 (9.1%)

3 (7.7%)

0.9

Variable

1st rSS Tertile (≤4)

(n = 35)

2nd rSS Tertile (4 – 12)

(n = 42)

3rd rSS Tertile (> 12)

(n = 37)

P value

Follow-Up Cumulative MACE^c

7 (20%)

14 (33.3%)

18 (48.6%)

0.037*

Death^c

4 (12.1%)

3 (8.8%)

16 (43.2%)

< 0.001*

Heart Failure^c

1 (2.9%)

10 (23.8%)

2 (5.4%)

0.006*

Non-Fatal MI^c

1 (2.9%)

1 (2.4%)

6 (16.2%)

0.029*

TLR^c

4 (11.4%)

4 (9.5%)

2 (5.4%)

0.7