Table 3 Multivariable-adjusted Cox models for MACE in females

Clinical predictor + CT-FFR ≤ 0.80

(model 1)

25.79

0.633

-

-

-

-

-

Diabetes mellitus

1.517 (1.005–2.289)

0.047

CT-FFR ≤ 0.80

2.512 (1.667–3.786)

0.000

model 1 + FAI[LAD] ≥ 70.1 (model 2)

30.72

0.643

0.054 (vs. model 1)

0.041 (-0.141-0.187)

0.189 (vs. model 1)

0.005 (-0.002-0.031)

0.259 (vs. model 1)

Diabetes mellitus

1.502 (0.995–2.267)

0.053

CT-FFR ≤ 0.80

2.486 (1.649–3.748)

0.000

FAI[LAD] ≥ −70.1

2.101 (1.055–4.182)

0.035

model 1 + FAI[LCX] ≥ 70.1 (model 3)

52.08

0.669

< 0.001 (vs. model 1)

0.161 (0.073–0.260)

< 0.001 (vs. model 1)

0.036 (0.008–0.090)

= 0.010 (vs. model 1)

Diabetes mellitus

1.461 (0.968–2.207)

0.071

CT-FFR ≤ 0.80

2.442 (1.619–3.683)

0.000

FAI[LCX] ≥ −70.1

3.230 (1.982–5.265)

0.000